Overexpression of caldesmon is associated with lymph node metastasis and poorer prognosis in patients with oral cavity squamous cell carcinoma.

abstract：:Both image and flow DNA cytometry were performed in isolated nuclei from paraffin-embedded tumor tissue of patients with small cell carcinoma of the lung (SCCL). In 14 patients tissue was obtained by surgery from the primary tumor. From 14 patients tissue was taken by autopsy. From two patients tissue obtained by both...

journal_title：Cancer

authors： Oud PS,Pahlplatz MM,Beck JL,Wiersma-Van Tilburg A,Wagenaar SJ,Vooijs GP

更新日期：1989-09-15 00:00:00

abstract：BACKGROUND:Total body irradiation (TBI) is commonly used with autologous bone marrow transplantation (BMT) for treatment of hematologic malignancies. Pulmonary complications of TBI can cause long-term morbidity and mortality. The authors have compared the pulmonary toxicity and efficacy of two different TBI fractionati...

journal_title：Cancer

authors： Gopal R,Ha CS,Tucker SL,Khouri IF,Giralt SA,Gajewski JL,Andersson BS,Cox JD,Champlin RE

更新日期：2001-10-01 00:00:00

abstract：:Fifty-one patients with confirmed bladder cancer have enrolled in a prospective evaluation of BCG immunotherapy. Following resection of existing tumors, patients were stratified according to tumor grade and number of previous recurrences and randomly assigned to control or BCG treatment groups. Immunotherapy consisted...

journal_title：Cancer

authors： Lamm DL,Thor DE,Winters WD,Stogdill VD,Radwin HM

更新日期：1981-07-01 00:00:00

abstract：:The prognostic significance of histologic tumor grade has been evaluated in 1537 women entered into the Ludwig Trials I-IV of adjuvant therapy for node-positive breast cancer. Tumor grade was determined on histologic review of primary tumor sections by two central review pathologists using a modification of the Bloom ...

journal_title：Cancer

authors： Davis BW,Gelber RD,Goldhirsch A,Hartmann WH,Locher GW,Reed R,Golouh R,Säve-Söderbergh J,Holloway L,Russell I

更新日期：1986-12-15 00:00:00

abstract：BACKGROUND:The objective of the current study was to investigate the effects and the morbidities of single-fraction stereotactic radiation therapy (SRT) for lung tumors. METHODS:A Microtron device was modified to deliver stereotactic irradiation under respiratory gating. Between August 1998 and December 2004, 59 malig...

journal_title：Cancer

authors： Hara R,Itami J,Kondo T,Aruga T,Uno T,Sasano N,Ohnishi K,Kiyozuka M,Fuse M,Ito M,Naoi K,Kohno Y

更新日期：2006-03-15 00:00:00

abstract：BACKGROUND:Despite the well-defined role of minimal residual disease (MRD) monitoring by real-time quantitative polymerase chain reaction (RT-PCR) for RUNX1/RUNX1T1 and CBFB-MYH11 transcripts in core binding factor (CBF) acute myeloid leukemia (AML) after intensive chemotherapy, there has been a paucity of data assessi...

journal_title：Cancer

authors： Yalniz FF,Patel KP,Bashir Q,Marin D,Ahmed S,Alousi AM,Chen J,Ciurea SO,Rezvani K,Popat UR,Shpall EJ,Champlin RE,Oran B

更新日期：2020-05-15 00:00:00

abstract：BACKGROUND:The authors hypothesized that the outcomes for young patients who present with primary osteosarcoma of flat bones or secondary osteosarcoma after other primary malignancies are similar because the sites of these tumors rarely makes them amenable to complete surgical resection. METHODS:The authors reviewed t...

journal_title：Cancer

authors： Pratt CB,Meyer WH,Rao BN,Pappo AS,Fleming ID,Luo X,Cain A,Kaste SC,Shearer PD,Jenkins JJ 3rd

更新日期：1997-09-15 00:00:00

abstract：:Two human Burkitt's lymphoma cell lines (HBL-4 and HBL-5) were established individually from two patients with small noncleaved cell lymphoma (Burkitt's type). The HBL-4 cell line is Epstein-Barr virus (EBV)-negative, and the HBL-5 cell line is EBV-positive. Cytogenetically, both cell lines had the same chromosomal tr...

journal_title：Cancer

authors： Abe M,Tasaki K,Tominaga K,Fukuhara S,Imai S,Osato T,Wakasa H

更新日期：1992-02-01 00:00:00

abstract：BACKGROUND:The purpose of the current study was to determine the prevalence of low bone mineral density (BMD) (ie, osteopenia) and identify factors associated with low BMD in young adult survivors of childhood acute lymphoblastic leukemia (ALL). METHODS:Dual energy x-ray absorptiometry was used to evaluate BMD in 74 r...

journal_title：Cancer

authors： Thomas IH,Donohue JE,Ness KK,Dengel DR,Baker KS,Gurney JG

更新日期：2008-12-01 00:00:00

abstract：BACKGROUND:Parathyroid hormone-related protein (PTHrP) has been shown to be the principal cause of humoral hypercalcemia associated with renal cell carcinoma (RCC). Recent studies have demonstrated that the amino-terminal region of PTHrP has growth factor-like activities, suggesting it may play a role in the developmen...

journal_title：Cancer

authors： Iwamura M,Wu W,Muramoto M,Ohori M,Egawa S,Uchida T,Baba S

更新日期：1999-09-15 00:00:00

abstract：:In a randomized series of 70 patients with with colo rectal adenocarcinoma, a comparison of systemic 5-fluorouracil chemotherapy administered as a continuous 120-hours infusion vs. intravenous bolus injection daily for 5 days demonstrated superiority of prolonged intravenous infusion. The most striking advantage of pr...

journal_title：Cancer

authors： Seifert P,Baker LH,Reed ML,Vaitkevicius VK

更新日期：1975-07-01 00:00:00

abstract：:A large lipoma and a large angiomyolipoma of the liver, one case each, are described. In the first case, a 24 X 14-cm homogeneous mass demonstrated a fatty density (-96H) on computed tomography (CT), echogenicity on sonography, and fine neovascular vessels on angiography in the right lobe of the liver. Histopathologic...

journal_title：Cancer

authors： Takayasu K,Shima Y,Muramatsu Y,Moriyama N,Yamada T,Makuuchi M,Hirohashi S

更新日期：1987-03-01 00:00:00

abstract：:Malignant lymphomas with multilobated nuclei are rare, recently recognized neoplasms of the immune system initially thought to be of T-cell type. Reported is a case of large cell lymphoma with multilobated nuclei in which immunologic marker studies demonstrated that the neoplastic cells had characteristics of B-lympho...

journal_title：Cancer

authors： Parfrey NA,Mann RB,Selonick SE,Beschorner WE

更新日期：1985-05-01 00:00:00

abstract：BACKGROUND:Clear cell tumors of the thyroid gland in general are uncommon. Metastatic renal cell carcinoma (RCC) to the thyroid gland is a rare occurrence but must be considered in the differential diagnosis of a thyroid gland clear cell neoplasm to prevent misclassification, potentially resulting in inappropriate clin...

journal_title：Cancer

authors： Heffess CS,Wenig BM,Thompson LD

更新日期：2002-11-01 00:00:00

abstract：:To investigate the utility of thallium 201 (Tl-201) thyroid scintigraphy for the detection of thyroid malignancies, early and delayed Tl-201 scintigraphy was done in 70 consecutive patients with a clinically solitary cold (Iodine 123 [I-123]) nodule. Early Tl-201 scintigraphy had a sensitivity of 100% and a specificit...

journal_title：Cancer

authors： Bleichrodt RP,Vermey A,Piers DA,de Langen ZJ

更新日期：1987-12-01 00:00:00

abstract：BACKGROUND:Microsatellite instability (MIN) appears to be a novel molecular mechanism in carcinogenesis and is believed to reflect multiple replication errors. The authors analyzed MIN in de novo acute leukemia and its association with expression of the human MSH3 (hMSH3) gene and point mutations of the N-ras gene. The...

journal_title：Cancer

authors： Tanosaki S,Inokuchi K,Shimada T,Dan K

更新日期：1998-08-01 00:00:00

abstract：:Thirty-seven lymphomas of bone were studied, including 33 diffuse large cell lymphomas, three undifferentiated (small noncleaved cell) lymphomas, and one well-differentiated (small) lymphocytic lymphoma. The large cell lymphomas were subclassified as large cleaved, large noncleaved, multilobated cell, and immunoblasti...

journal_title：Cancer

authors： Clayton F,Butler JJ,Ayala AG,Ro JY,Zornoza J

更新日期：1987-11-15 00:00:00

abstract：BACKGROUND:Both genetic and epigenetic changes in nonsmall cell lung cancer (NSCLC) are known to be a common event. METHODS:Mutations in the epidermal growth factor receptor gene (EGFR), HER-2, and KRAS and the methylation profile of 9 genes for NSCLC were analyzed and correlated with clinical and histologic data. RE...

journal_title：Cancer

authors： Suzuki M,Shigematsu H,Iizasa T,Hiroshima K,Nakatani Y,Minna JD,Gazdar AF,Fujisawa T

更新日期：2006-05-15 00:00:00

abstract：BACKGROUND:Optimal chemotherapy for treating mixed-phenotype acute leukemia (MPAL) and the role of hematopoietic stem cell transplantation (HSCT) remain uncertain. Major limitations in interpreting available data are MPAL's rarity and the use of definitions other than the currently widely accepted criteria: the World H...

journal_title：Cancer

authors： Orgel E,Alexander TB,Wood BL,Kahwash SB,Devidas M,Dai Y,Alonzo TA,Mullighan CG,Inaba H,Hunger SP,Raetz EA,Gamis AS,Rabin KR,Carroll AJ 3rd,Heerema NA,Berman JN,Woods WG,Loh ML,Zweidler-McKay PA,Horan JT,Children's

更新日期：2020-02-01 00:00:00

abstract：BACKGROUND:Cancer rates in immigrant populations are frequently found to be intermediate between the country of origin and the adopted country. Such observations play an important role in establishing the environmental origin of cancer. Chinese now constitute the third largest group immigrating to New York City. METHO...

journal_title：Cancer

authors： Stellman SD,Wang QS

更新日期：1994-02-15 00:00:00

abstract：BACKGROUND:Most patients with cutaneous squamous cell carcinoma (cSCC) of the head and neck (HN) are at low-risk (<5%) of developing metastatic SCC to regional lymph nodes. However, patients with unfavorable clinicopathologic factors often are under appreciated by clinicians but remain at higher risk for developing met...

journal_title：Cancer

authors： Veness MJ,Palme CE,Morgan GJ

更新日期：2006-06-01 00:00:00

abstract：:Seventeen patients with cancer or aplastic anemia received demeclocycline as treatment for hyponatremia. Prior to demeclocycline therapy no patients showed clinical signs of fluid overload or saline depletion. In all patients inappropriately concentrated urine (mean urine osmolality = 548 mOSM/kg H2O) or increased uri...

journal_title：Cancer

authors： Trump DL

更新日期：1981-06-15 00:00:00

abstract：BACKGROUND:Although there have been several reports of cytologic features for salivary duct carcinoma (SDC), it still can be difficult to diagnose patients with these tumor accurately at the time of fine-needle aspiration (FNA). Review of the literature indicates that, immunohistochemically, SDC expresses androgen rece...

journal_title：Cancer

authors： Moriki T,Ueta S,Takahashi T,Mitani M,Ichien M

更新日期：2001-10-25 00:00:00

abstract：:Seventy-seven patients with relapsed or refractory acute leukemia and three with acute blastic chronic myeloid leukemia (CML) were treated in an open Phase II study using mitoxantrone 12 mg/m2 intravenously daily X 5 days. Complete remission (CR) was achieved in 32 of 80 (40%), including 23/45 (52%) with relapsed acut...

journal_title：Cancer

authors： Bezwoda WR,Bernasconi C,Hutchinson RM,Winfield DA,de Bock R,Mandelli F

更新日期：1990-08-01 00:00:00

abstract：BACKGROUND:Cancer and its treatment lead to increased financial distress for patients. To the authors' knowledge, to date, no standardized patient-reported outcome measure has been validated to assess this distress. METHODS:Patients with AJCC Stage IV solid tumors receiving chemotherapy for at least 2 months were recr...

journal_title：Cancer

authors： de Souza JA,Yap BJ,Wroblewski K,Blinder V,Araújo FS,Hlubocky FJ,Nicholas LH,O'Connor JM,Brockstein B,Ratain MJ,Daugherty CK,Cella D

更新日期：2017-02-01 00:00:00

abstract：:High dose methotrexate followed by citrovorum factor reversal has been utilized in twenty-six patients with advanced cancer. Four of 10 patients with head and neck cancer had an objective response. One of 7 patients with metastatic osteosarcoma to the lungs had stabilization with twenty treatments over 23 months. One ...

journal_title：Cancer

authors： Ambinder EP,Perloff M,Ohnuma T,Biller HF,Holland JF

更新日期：1979-04-01 00:00:00

abstract：BACKGROUND:Infection with oncogenic-type human papillomavirus (HPV) and consecutive cytologic abnormalities of the uterine cervix precede the evolution of carcinoma. However, the specificity of both changes is too low to predict the true malignant potential of the change in a given time point, because the majority of t...

journal_title：Cancer

authors： Bollmann R,Méhes G,Speich N,Schmitt C,Bollmann M

更新日期：2005-04-25 00:00:00

abstract：BACKGROUND:Aberrant DNA methylation, which results in leukemogenesis, is frequent in patients with myelodysplastic syndromes (MDS) and is a potential target for pharmacologic therapy. Decitabine indirectly depletes methylcytosine and causes hypomethylation of target gene promoters. METHODS:A total of 170 patients with...

journal_title：Cancer

authors： Kantarjian H,Issa JP,Rosenfeld CS,Bennett JM,Albitar M,DiPersio J,Klimek V,Slack J,de Castro C,Ravandi F,Helmer R 3rd,Shen L,Nimer SD,Leavitt R,Raza A,Saba H

更新日期：2006-04-15 00:00:00

abstract：:Seventeen patients with carcinoma confined to the pancreas and the peripancreatic area received preoperative radiation therapy in an attempt to increase the resectability rate and to reduce the incidence of recurrence. The tumors were considered either unresectable or of borderline resectability. The radiation dose ra...

journal_title：Cancer

authors： Pilepich MV,Miller HH

更新日期：1980-11-01 00:00:00

abstract：:Thirty-eight metastatic breast cancer patients were treated with aminoglutethimide. All patients had progressive metastatic disease following initial response to Tamoxifen therapy. Thirty-two patients were evaluable for response, of these, two patients (6%) had complete remission, 13 patients (41%) had partial respons...

journal_title：Cancer

authors： Buzdar AU,Powell KC,Legha SS,Blumenschein GR

更新日期：1982-11-01 00:00:00