Mixed-phenotype acute leukemia: A cohort and consensus research strategy from the Children's Oncology Group Acute Leukemia of Ambiguous Lineage Task Force.

abstract：BACKGROUND:Ethnic disparities in colorectal cancer (CRC) mortality are observed in the United States. The authors studied this among minority New Yorkers with CRC. METHODS:In a study of CRC patients in a New York City teaching hospital, 5-year data on demographics and clinical features were reviewed. Adjusted cancer-r...

journal_title：Cancer

authors： Kanna B,Narang TK,Atwal T,Paul D,Azeez S

更新日期：2009-12-01 00:00:00

abstract：BACKGROUND:Karyotypic abnormalities in sporadic Burkitt lymphoma (BL) have been described extensively. However, to the authors' knowledge, very limited studies have focused on the secondary chromosomal abnormalities in pediatric BL as compared with those of adult BL and on their prognostic impact. METHODS:A retrospect...

journal_title：Cancer

authors： Onciu M,Schlette E,Zhou Y,Raimondi SC,Giles FJ,Kantarjian HM,Medeiros LJ,Ribeiro RC,Pui CH,Sandlund JT

更新日期：2006-09-01 00:00:00

abstract：:Two human Burkitt's lymphoma cell lines (HBL-4 and HBL-5) were established individually from two patients with small noncleaved cell lymphoma (Burkitt's type). The HBL-4 cell line is Epstein-Barr virus (EBV)-negative, and the HBL-5 cell line is EBV-positive. Cytogenetically, both cell lines had the same chromosomal tr...

journal_title：Cancer

authors： Abe M,Tasaki K,Tominaga K,Fukuhara S,Imai S,Osato T,Wakasa H

更新日期：1992-02-01 00:00:00

abstract：:Patients with ER positive primary tumors usually have initial metastases at the more favorable sites. Twelve out of 14 patients with ER positive had first site of metastases in either bone or soft tissue. In contrast, 13 of 17 patients with negative ER developed first metastases in viscera. ER positive patients respon...

journal_title：Cancer

authors： Singhakowinta A,Saunders DE,Brooks SC,Samal B,Vaitkevicius VK

更新日期：1980-12-15 00:00:00

abstract：:Since June 1978, 57 patients with primary osteogenic sarcoma of an extremity were treated with high-dose methotrexate (HDMTX) and citrovorum factor rescue (CFR), Adriamycin, and the combination of bleomycin, cyclophosphamide and dactinomycin (BCD) given for 4-16 weeks prior to definitive surgery. Histologic examinatio...

journal_title：Cancer

authors： Rosen G,Caparros B,Huvos AG,Kosloff C,Nirenberg A,Cacavio A,Marcove RC,Lane JM,Mehta B,Urban C

更新日期：1982-03-15 00:00:00

abstract：BACKGROUND:Patients with testicular cancer can be cured by cisplatin-based chemotherapy in many cases. Thus, concern about possible late toxicities of treatment is warranted. METHODS:In this investigation, the absolute number of natural killer (NK) cells according to their CD56+ phenotype, NK cell activity, and antibo...

journal_title：Cancer

authors： Krainer M,Wolf H,Michl I,Wiltschke C,Budinsky A,Kaider A,Kratzik C,Eibl MM,Zielinski CC

更新日期：1995-01-15 00:00:00

abstract：:Immunoblastic sarcoma is a malignancy of transformed lymphocytes with a high association of occurrence in patients with immune disorders. The youngest previously reported case occurred in a 6-year-old child with immunoblastic lymphadenopathy. The authors report the finding of immunoblastic sarcoma of B-cells in a prev...

journal_title：Cancer

authors： Larson T,Katz DA,Mailliard JA

更新日期：1984-11-01 00:00:00

abstract：BACKGROUND:The authors attempted to obtain shared proteins among lung carcinoma cells by column chromatographies. A glycoprotein with approximately 500 kDa isolated from QG56 cells showed an identical amino acid sequence to 90K/Mac-2 binding protein (M2BP). This protein has been reported to be highly expressed and to m...

journal_title：Cancer

authors： Ozaki Y,Kontani K,Hanaoka J,Chano T,Teramoto K,Tezuka N,Sawai S,Fujino S,Yoshiki T,Okabe H,Ohkubo I

更新日期：2002-11-01 00:00:00

abstract：:The Nb rat prostatic adenocarcinoma is a well-characterized, hormonally induced family of tumors that are all readily transplantable into congenitally athymic (nude) mice. Because of this versatile heterotransplantation model, multiple replicate copies of individual tumors can be studied "in rodent." We have extended ...

journal_title：Cancer

authors： Drago JR,Maurer RE,Gershwin ME,Eckels D,Palmer JM

更新日期：1979-08-01 00:00:00

abstract：BACKGROUND:It has been suggested that tissue factor (TF) plays an important role in tumor metastasis. Its expression in sarcoma cells was reported to up-regulate the vascular endothelial growth factor (VEGF) gene and thereby enhance tumor angiogenesis, which is essential to tumor metastasis. Although many malignant tum...

journal_title：Cancer

authors： Seto S,Onodera H,Kaido T,Yoshikawa A,Ishigami S,Arii S,Imamura M

更新日期：2000-01-15 00:00:00

abstract：:Results of 567 thin-needle aspiration biopsies of head and neck lesions are reviewed. Cases included lymph nodes, salivary glands, thyroid, soft tissue and bone lesions. For the entire series, 17 patients had unsatisfactory aspirations. There were 12 false negative reports and 4 false positive reports, rates of 2.1% a...

journal_title：Cancer

authors： Frable WJ,Frable MA

更新日期：1979-04-01 00:00:00

abstract：BACKGROUND:The antiviral, proapoptotic, antiproliferative gene 2'-5' oligoadenylate synthetase (2-5OAS1) converts adenosine triphosphate into a series of 2'-5' oligoadenylates (2-5A). In turn, 2-5A activates latent ribonuclease (RNaseL), a candidate hereditary prostate cancer gene. OAS1 polymorphism (reference single n...

journal_title：Cancer

authors： Mandal S,Abebe F,Chaudhary J

更新日期：2011-12-15 00:00:00

abstract：BACKGROUND:The objective of this study was to evaluate changes in clinical and pathologic characteristics of prostate cancer in patients who underwent surgery at a large tertiary care center in the context of increased use of active surveillance (AS) and minimally invasive surgery (MIS). METHODS:The authors retrospect...

journal_title：Cancer

authors： Silberstein JL,Vickers AJ,Power NE,Fine SW,Scardino PT,Eastham JA,Laudone VP

更新日期：2011-11-01 00:00:00

abstract：:There were no significant differences between the mean blood plasma (leukocyte-free) RNAase activity among 128 healthy women volunteers age 13-70 and 49 women with benign gynecological tumors. Exceptions to this finding were three apparently healthy women volunteers who had plasma enzyme activity which was higher than...

journal_title：Cancer

authors： Sheid B,Lu T,Pedrinan L,Nelson JH Jr

更新日期：1977-05-01 00:00:00

abstract：BACKGROUND:Patients with gastric cancer have a poor prognosis and can be cured by surgery only if the cancer is detected in an early stage. Extended surgery, down staging with chemotherapy before operation, and new postoperative treatments are recent approaches to increase survival rates. Categorizing patients' prognos...

journal_title：Cancer

authors： Ganesh S,Sier CF,Heerding MM,van Krieken JH,Griffioen G,Welvaart K,van de Velde CJ,Verheijen JH,Lamers CB,Verspaget HW

更新日期：1996-03-15 00:00:00

abstract：:A humoral microcytotoxicity assay has been used to study the immune response to human malignant astrocytic tumors. Two series are described. When the assay was performed under uniform, ideal conditions, the sera from 36 of 45 patients with these tumors (80%) produced significant cytotoxicity against allogeneic astrocy...

journal_title：Cancer

authors： Wood WC,Kornblith PL,Quindlen EA,Pollock LA

更新日期：1979-01-01 00:00:00

abstract：:Patients with ulcerative colitis are at increased risk of developing adenocarcinoma of the colon. The authors describe a patient whose colonic neoplasm demonstrated histologic characteristics of both an adenocarcinoma and a carcinoid tumor and which was pathologically identical to a appendiceal adenocarcinoid. Because...

journal_title：Cancer

authors： Lyss AP,Thompson JJ,Glick JH

更新日期：1981-08-01 00:00:00

abstract：BACKGROUND:Vascular endothelial growth factor (VEGF) signaling is a target for antiangiogenic cancer therapy. The authors have previously observed that up to 40% of vessels in colorectal carcinoma (CRC) tumors are negative for VEGF receptor 2 (VEGFR2) expression. Differential activity of transforming growth factor beta...

journal_title：Cancer

authors： Kuczynski EA,Viloria-Petit AM,Coomber BL

更新日期：2011-12-15 00:00:00

abstract：BACKGROUND:A high cure rate may be attained for locally advanced, undifferentiated nasopharyngeal carcinoma (NPC) in children, provided that a combined modality of treatment is employed. Both local and systemic therapies are necessary. Results at a single pediatric institution were analyzed. METHODS:From November 1988...

journal_title：Cancer

authors： Zubizarreta PA,D'Antonio G,Raslawski E,Gallo G,Preciado MV,Casak SJ,Scopinaro M,Morales G,Sackmann-Muriel F

更新日期：2000-08-01 00:00:00

abstract：BACKGROUND:LAMP3 is a newly described hypoxia regulated gene of potential interest in hypoxia-induced therapy resistance and metastasis. The prognostic value of LAMP3 in breast cancer was investigated. METHODS:Expression levels of LAMP3 in breast cancer cell lines and patient tissues were determined by real-time polym...

journal_title：Cancer

authors： Nagelkerke A,Mujcic H,Bussink J,Wouters BG,van Laarhoven HW,Sweep FC,Span PN

更新日期：2011-08-15 00:00:00

abstract：BACKGROUND:Malignant cells exhibit increased glycolytic metabolism, and in many cases increased glucose transporter gene expression. The authors hypothesized that GLUT1 glucose transporter expression is increased in colorectal carcinoma, and that the degree of expression might have prognostic significance. METHODS:GLU...

journal_title：Cancer

authors： Haber RS,Rathan A,Weiser KR,Pritsker A,Itzkowitz SH,Bodian C,Slater G,Weiss A,Burstein DE

更新日期：1998-07-01 00:00:00

abstract：:In three cases of the spontaneous rupture of hepatocellular carcinoma, emergent transcatheter hepatic arterial embolization was performed for controlling the intraperitoneal hemorrhage. No more transfusions were required after embolization. Operation was carried out on the 10th, 5th, and 5th day, respectively, after l...

journal_title：Cancer

authors： Chen MF,Jan YY,Lee TY

更新日期：1986-07-15 00:00:00

abstract：:External-beam irradiation of prostatic cancer was introduced at Stanford in 1956. The program has sought to determine the following: whether prostatic carcinoma can be cured by external beam radiation therapy, with what frequency this can be accomplished, which patients are best suited for irradiation, and what techni...

journal_title：Cancer

authors： Bagshaw MA,Ray GR,Cox RS

更新日期：1987-08-01 00:00:00

abstract：BACKGROUND:Inactivation of the PTEN suppressor gene has been shown to occur in the majority of endometrial cancer cases. Somatic PTEN inactivation by deletion and/or mutation, the first detectible change of endometrial carcinogenesis, has been reported to occur at a high frequency in the endometrium of normal premenopa...

journal_title：Cancer

authors： Lin MC,Burkholder KA,Viswanathan AN,Neuberg D,Mutter GL

更新日期：2009-05-15 00:00:00

abstract：BACKGROUND:Older women are less likely than younger women to receive definitive care for a new diagnosis of breast cancer, but the reasons are not well understood. Although coordination of referral among specialists is an important component of quality of care, it has not been studied as a factor that contributes to ob...

journal_title：Cancer

authors： Thwin SS,Fink AK,Lash TL,Silliman RA

更新日期：2005-09-01 00:00:00

abstract：:Models play a fundamental role in all sciences. Scientific theories can be understood as "intellectual models" of the relations and interrelations between the elements of the science. Such relational models consider the scientific topics as "systems," and may therefore be called "system models." The basic elements of ...

journal_title：Cancer

authors： Brock N,Schneider B

更新日期：1984-09-15 00:00:00

abstract：:A retrospective analysis of 74 cases of transitional cell carcinoma of the renal pelvis and ureter treated at this institution over the past 30 years is presented. When nephrectomy alone or incomplete nephroureterectomy was performed, subsequent transitional cell carcinoma developed in 30% of the ureteral stumps. Subs...

journal_title：Cancer

authors： Strong DW,Pearse HD

更新日期：1976-11-01 00:00:00

abstract：BACKGROUND:A phase 1 trial was used to evaluate a combination of cisplatin, gemcitabine, and escalating doses of veliparib in patients with untreated advanced pancreatic ductal adenocarcinoma (PDAC) in 2 cohorts: a germline BRCA1/2-mutated (BRCA+) cohort and a wild-type BRCA (BRCA-) cohort. The aims were to determine t...

journal_title：Cancer

authors： O'Reilly EM,Lee JW,Lowery MA,Capanu M,Stadler ZK,Moore MJ,Dhani N,Kindler HL,Estrella H,Maynard H,Golan T,Segal A,Salo-Mullen EE,Yu KH,Epstein AS,Segal M,Brenner R,Do RK,Chen AP,Tang LH,Kelsen DP

更新日期：2018-04-01 00:00:00

abstract：BACKGROUND:Serum alpha-L-fucosidase activity is considered a marker of hepatocellular carcinoma. To the authors' knowledge, its clinical usefulness in the early detection of hepatocellular carcinoma in the follow-up of cirrhotic patients has not been reported previously. METHODS:The authors prospectively studied serum...

journal_title：Cancer

authors： Giardina MG,Matarazzo M,Morante R,Lucariello A,Varriale A,Guardasole V,De Marco G

更新日期：1998-12-15 00:00:00

abstract：:The individual medical histories in the files of the Oxford Record Linkage Study for the years 1963 to 1967 were analyzed to ascertain any previously unsuspected associations between cancers of the large bowel and other diseases in individuals, and to quantify the relative risks of disorders already known to be associ...

journal_title：Cancer

authors： Adelstein P,Baldwin JA,Fedrich J

更新日期：1979-06-01 00:00:00