Hypoxic regulation and prognostic value of LAMP3 expression in breast cancer.

abstract：BACKGROUND:Men who receive androgen-deprivation therapy (ADT) for prostate cancer experience several side effects from this treatment. A few recent studies have examined the cognitive implications of ADT and how they impact a patient's treatment decision-making, occupational pursuits, and quality of life. For this repo...

journal_title：Cancer

authors： Nelson CJ,Lee JS,Gamboa MC,Roth AJ

更新日期：2008-09-01 00:00:00

abstract：:Retrospective immunocytochemical study of prolactin, growth hormone, ACTH, TSH and gonadotropins was performed on 150 pituitary adenomas from 142 patients and the results were correlated with clinical manifestations. There were 60 prolactin-positive tumors, 13 growth hormone-positive tumors, nine ACTH-positive tumors ...

journal_title：Cancer

authors： Mukai K

更新日期：1983-08-15 00:00:00

abstract：:The observation, in 1980, of a rapid increase in platelet counts as a result of administration of intravenous immunoglobulin (IVIG) in a patient with immune thrombocytopenic purpura (ITP) was followed by clinical studies confirming the efficacy of this new treatment alternative in ITP. Simultaneously, new sensitive as...

journal_title：Cancer

authors： Imbach P

更新日期：1991-09-15 00:00:00

abstract：BACKGROUND:The objective of this study was to characterize chronic disease, health-related quality of life (HRQOL), emotional distress, and social attainment among long-term survivors of neuroblastoma. METHODS:Chronic health conditions among 136 ≥10-year neuroblastoma survivors (median age, 31.9 years; range, 20.2-54....

journal_title：Cancer

authors： Wilson CL,Brinkman TM,Cook C,Huang S,Hyun G,Green DM,Furman WL,Bhakta N,Ehrhardt MJ,Krasin MJ,Robison LL,Ness KK,Hudson MM

更新日期：2020-03-15 00:00:00

abstract：BACKGROUND:Previous studies in the literature have suggested that radiolabeled F(ab')2 fragments might be superior to whole immunoglobulin G (IgG) for imaging and therapy of cancer because of their greater penetration in tumors. To test this hypothesis, the authors compared tumor and normal tissue uptake along with pla...

journal_title：Cancer

authors： Murray JL,Rosenblum MG,Zhang HZ,Podoloff DA,Kasi LP,Curley SA,Chan JC,Roh M,Hohn DC,Brewer H

更新日期：1994-02-01 00:00:00

abstract：BACKGROUND:Adenosquamous/squamous cell carcinoma of the gallbladder generally has been considered a lethal disease. The objective of this study was to clarify the effectiveness of resection for patients with adenosquamous/squamous cell carcinoma of the gallbladder. METHODS:Twenty-nine patients who underwent resection ...

journal_title：Cancer

authors： Oohashi Y,Shirai Y,Wakai T,Nagakura S,Watanabe H,Hatakeyama K

更新日期：2002-06-01 00:00:00

abstract：BACKGROUND:New biologic prognostic factors are needed to guide the treatment of patients with colorectal cancer. The prognostic value of the altered expression of the cell surface glycoprotein gp78, which has been implicated in tumor-cell invasion and metastasis as an autocrine motility factor (AMF) receptor, was evalu...

journal_title：Cancer

authors： Nakamori S,Watanabe H,Kameyama M,Imaoka S,Furukawa H,Ishikawa O,Sasaki Y,Kabuto T,Raz A

更新日期：1994-10-01 00:00:00

abstract：BACKGROUND:Breast cancer is the most common cancer and the second leading cause of cancer death among women in the United States; annual breast cancer deaths are exceeded only by those for lung cancer. METHODS:Data from the Surveillance, Epidemiology, and End Results (SEER) program registry of the National Cancer Inst...

journal_title：Cancer

authors： Berg JW,Hutter RV

更新日期：1995-01-01 00:00:00

abstract：BACKGROUND:The objective of this study was to define the effects of socioeconomic status (SES) and other demographic variables on outcomes for patients with pancreatic adenocarcinoma. METHODS:Florida cancer registry and inpatient hospital data were queried for pancreatic adenocarcinoma diagnosed from 1998 to 2002. RE...

journal_title：Cancer

authors： Cheung MC,Yang R,Byrne MM,Solorzano CC,Nakeeb A,Koniaris LG

更新日期：2010-02-01 00:00:00

abstract：:Most patients with colorectal carcinoma undergo attempts at curative surgery. However, some present with metastatic disease and many others ultimately relapse. Most recurrences of colorectal cancer are not resectable and require nonsurgical approaches such as chemotherapy and radiation therapy directed against local r...

journal_title：Cancer

authors： Vaughn DJ,Haller DG

更新日期：1993-06-15 00:00:00

abstract：BACKGROUND:To the authors' knowledge, little is known to date regarding the prognostic relevance of measuring serum levels of vascular endothelial growth factor (VEGF), a potent stimulator of angiogenesis, in patients with colon carcinoma who undergo surgery. METHODS:Preoperative and postoperative VEGF serum levels we...

journal_title：Cancer

authors： De Vita F,Orditura M,Lieto E,Infusino S,Morgillo F,Martinelli E,Castellano P,Romano C,Ciardiello F,Catalano G,Pignatelli C,Galizia G

更新日期：2004-01-15 00:00:00

abstract：BACKGROUND:Optimal treatments for vulvar and vaginal melanomas (VVMs) have not been identified. Herein, the authors compare molecular profiles between VVM and nongynecologic melanoma (NGM) subtypes with the objective of identifying novel, targetable biomarkers. METHODS:In total, 2304 samples of malignant melanoma that...

journal_title：Cancer

authors： Hou JY,Baptiste C,Hombalegowda RB,Tergas AI,Feldman R,Jones NL,Chatterjee-Paer S,Bus-Kwolfski A,Wright JD,Burke WM

更新日期：2017-04-15 00:00:00

abstract：BACKGROUND:Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is the only treatment with a curative potential for myelodysplastic syndrome (MDS) patients. Allo-HSCT has substantial risks, particularly in the elderly, and its role for older MDS patients has yet to be defined. METHODS:We analyzed 88 MDS pati...

journal_title：Cancer

authors： Yucel OK,Saliba RM,Rondon G,Ahmed S,Alousi A,Bashir Q,Ciurea SO,Popat U,Khouri I,Marin D,Rezvani K,Kebriaei P,Shpall EJ,Champlin RE,Oran B

更新日期：2017-07-15 00:00:00

abstract：:An autopsy case of prostaglandin E-producing hepatocellular carcinoma with hypercalcemia is presented in this article. A 72-year-old man showed high serum calcium levels (14.2 to 17.3 mg/100 ml) and hypophosphatemia. The plasma level of immunoreactive parathyroid hormone was below the normal range. Administration of o...

journal_title：Cancer

authors： Ikeda T,Tozuka S,Hasumura Y,Takeuchi J

更新日期：1988-05-01 00:00:00

abstract：BACKGROUND:The 5-year survival rate of patients with submucosal (sm) esophageal carcinoma continues to be much worse than that with intramucosal (m) lesions. The reasons are unclear, but matrix metalloproteinases (MMPs) and membrane type matrix metalloproteinases (MT-MMPs) are known to be involved in degradation of ext...

journal_title：Cancer

authors： Ohashi K,Nemoto T,Nakamura K,Nemori R

更新日期：2000-05-15 00:00:00

abstract：BACKGROUND:The objective of the current study was to correlate pretreatment computed tomography and magnetic resonance imaging studies with outcomes for patients with squamous or basal cell carcinoma of the skin and clinical perineural invasion. METHODS:Between 1986 and 2002, 45 patients were treated with radiotherapy...

journal_title：Cancer

authors： Galloway TJ,Morris CG,Mancuso AA,Amdur RJ,Mendenhall WM

更新日期：2005-03-15 00:00:00

abstract：:A system for staging the clinical status of patients with soft tissue sarcomas is presented, based on the clinical characteristics of the primary tumor (size, extension), the involvement of lymph nodes, the presence of metastases, and the grade of the tumor. This represents the TNM system with grade of tumor (G) added...

journal_title：Cancer

authors： Russell WO,Cohen J,Enzinger F,Hajdu SI,Heise H,Martin RG,Meissner W,Miller WT,Schmitz RL,Suit HD

更新日期：1977-10-01 00:00:00

abstract：BACKGROUND:The current study was conducted to assess the efficacy and toxicity of sorafenib as front-line therapy in patients with stage IIIB (pleural effusion) or IV nonsmall cell lung cancer (NSCLC). METHODS:Patients received sorafenib 400 mg twice daily by mouth continuously, and were evaluated every 2 weeks during...

journal_title：Cancer

authors： Dy GK,Hillman SL,Rowland KM Jr,Molina JR,Steen PD,Wender DB,Nair S,Mandrekar S,Schild SE,Adjei AA,North Central Cancer Treatment Group Study N0326.

更新日期：2010-12-15 00:00:00

abstract：BACKGROUND:The relationship between serum levels of matrix metalloproteinase-2 (MMP-2) and MMP-3 and recurrence in patients with urothelial carcinoma after complete resection was studied to determine whether the enzymes could be a new predictor of recurrence. METHODS:Serum levels of MMP-2 and MMP-3 in 146 healthy cont...

journal_title：Cancer

authors： Gohji K,Fujimoto N,Komiyama T,Fujii A,Ohkawa J,Kamidono S,Nakajima M

更新日期：1996-12-01 00:00:00

abstract：BACKGROUND:Radiofrequency (RF)-induced tissue coagulation represents a new approach for the thermal destruction of tumors within the liver. The purpose of the current study was to 1) assess technique safety; 2) determine the extent and evolution of induced cellular damage; and 3) correlate the observed pathologic effec...

journal_title：Cancer

authors： Goldberg SN,Gazelle GS,Compton CC,Mueller PR,Tanabe KK

更新日期：2000-06-01 00:00:00

abstract：BACKGROUND:It has been reported that MUC1 is an important prognostic factor in several cancers. This study investigated the importance of MUC1 as a prognostic factor in mass-forming intrahepatic cholangiocarcinoma (m-ICC). METHODS:In 50 patients with m-ICC who had undergone hepatectomy, expression of MUC1 was investig...

journal_title：Cancer

authors： Matsumura N,Yamamoto M,Aruga A,Takasaki K,Nakano M

更新日期：2002-03-15 00:00:00

abstract：BACKGROUND:English and Chinese are two of the most widely used primary languages in the world. Patients in many cancer centers have a variety of ethnic backgrounds and primary languages. The comparability of version 4 of the English and Chinese versions of the Functional Assessment of Cancer Therapy-General (FACT-G) an...

journal_title：Cancer

authors： Cheung YB,Thumboo J,Goh C,Khoo KS,Che W,Wee J

更新日期：2004-12-15 00:00:00

abstract：:Ninety-five patients with non-oat cell lung cancer underwent resection of all apparent disease and were followed for a minimum of 36 months. Incidence of recurrence was 34% in 47 patients with N0 disease, 65% in 32 patients with N1 disease, and 81.3% in 16 patients with N2 disease (P less than 0.02 and P less than 0.0...

journal_title：Cancer

authors： Iascone C,DeMeester TR,Albertucci M,Little AG,Golomb HM

更新日期：1986-02-01 00:00:00

abstract：BACKGROUND:Leptomeningeal disease (LMD) involves the spread of malignant cells from solid tumors to the cerebrospinal fluid or to the leptomeninges. LMD has a very poor prognosis and it is difficult to diagnose and follow with traditional diagnostic tools. The purposes of this study were to characterize cognitive funct...

journal_title：Cancer

authors： Sherman AM,Jaeckle K,Meyers CA

更新日期：2002-09-15 00:00:00

abstract：:Over the last 20 to 30 years, a recognition and general acceptance of the entity of malignant fibrous histiocytoma and monophasic synovial sarcoma has occurred. The introduction of these diagnostic categories among the generic group of spindle cell sarcomas now requires a reevaluation of the more traditional and histo...

journal_title：Cancer

authors： Scott SM,Reiman HM,Pritchard DJ,Ilstrup DM

更新日期：1989-08-15 00:00:00

abstract：BACKGROUND AND METHODS:The antiemetic activity of ondansetron (Zofran, Glaxo Pharmaceuticals, Research Triangle Park, NC) was evaluated in 25 patients with recurrent melanoma who were treated sequentially with dacarbazine (DTIC), vinblastine, and cisplatin. The antiemetic regimen included ondansetron alone in 11 patien...

journal_title：Cancer

authors： Legha SS,Hodges C,Ring S

更新日期：1992-10-01 00:00:00

abstract：:The survival of cervical carcinoma patients with paraaortic/high common iliac nodal metastases was evaluated by retrospective chart review during a 13-year interval. Thirty-three patients with cervical carcinoma and surgically documented nodal metastases received primary, extended-field radiation therapy. Overall 2-ye...

journal_title：Cancer

authors： Podczaski E,Stryker JA,Kaminski P,Ndubisi B,Larson J,DeGeest K,Sorosky J,Mortel R

更新日期：1990-07-15 00:00:00

abstract：:Malignant lymphomas with multilobated nuclei are rare, recently recognized neoplasms of the immune system initially thought to be of T-cell type. Reported is a case of large cell lymphoma with multilobated nuclei in which immunologic marker studies demonstrated that the neoplastic cells had characteristics of B-lympho...

journal_title：Cancer

authors： Parfrey NA,Mann RB,Selonick SE,Beschorner WE

更新日期：1985-05-01 00:00:00

abstract：BACKGROUND:Ductal carcinoma in situ (DCIS) of the male breast is an uncommon disease, accounting for approximately 7% of all male breast carcinomas. Compared with invasive carcinomas of the breast, the prognosis associated with DCIS in men is excellent; however, clinical features, pathology, and treatment of this disea...

journal_title：Cancer

authors： Camus MG,Joshi MG,Mackarem G,Lee AK,Rossi RL,Munson JL,Buyske J,Barbarisi LJ,Sanders LE,Hughes KS

更新日期：1994-08-15 00:00:00

abstract：:Adrenal cortical carcinoma is an uncommon neoplasm in children. Only a handful of congenital adrenal cortical carcinoma cases have been described. A newborn who had metastatic adrenal cortical carcinoma (skin metastases and cerebral lesions) is described. This patient underwent surgical resection of the right adrenal ...

journal_title：Cancer

authors： Saracco S,Abramowsky C,Taylor S,Silverman RA,Berman BW

更新日期：1988-08-01 00:00:00