Scar carcinomas of the lung in a histoplasmosis endemic area.

Abstract:

:Seventeen cases of pulmonary scar carcinomas were found in 112 surgically resected pulmonary carcinomas from 1985 through 1988 in a hospital situated in a histoplasmosis endemic area. These carcinomas can be divided into two types: Type I, mucinous; and Type II, non-mucinous (Clara cell). Each type of carcinoma constitutes a discrete group in reference to gross features, histologic and ultrastructural cell types, and the nature of the scar. The scar in Type I carcinomas appears mostly desmoplastic. The majority of Type II carcinomas appear to have arisen around a preexisting histoplasmosis granuloma which contains yeast organisms on microscopic examination. Pulmonary scar carcinoma is not a single discrete clinicopathologic entity. It appears that peripheral carcinomas of different histogenesis are incorporated in this category.

journal_name

Cancer

journal_title

Cancer

authors

Yoneda K

doi

10.1002/1097-0142(19900101)65:1<164::aid-cncr28206

subject

Has Abstract

pub_date

1990-01-01 00:00:00

pages

164-8

issue

1

eissn

0008-543X

issn

1097-0142

journal_volume

65

pub_type

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