B-cell lymphoma in severe combined immunodeficiency not associated with the Epstein-Barr virus.

abstract：BACKGROUND:In spite of many reports, it remains unclear whether the presence of tumor cells in circulating blood flow predicts a poor prognosis. METHODS:Competitive seminested reverse transcriptase-polymerase chain reaction (RT-PCR), a technique for the quantitative detection of tumor cells, was applied to detect the ...

journal_title：Cancer

authors： Sadahiro S,Suzuki T,Tokunaga N,Yurimoto S,Yasuda S,Tajima T,Makuuchi H,Murayama C,Matsuda K

更新日期：2001-09-01 00:00:00

abstract：:Chemokines are chemoattractant cytokines that regulate the trafficking and activation of leukocytes and other cell types under a variety of inflammatory and noninflammatory conditions. Over the past few years, studies have increasingly shown that chemokines play an important role in several aspects of tumor progressio...

journal_title：Cancer

authors： Ruffini PA,Morandi P,Cabioglu N,Altundag K,Cristofanilli M

更新日期：2007-06-15 00:00:00

abstract：BACKGROUND:The Akt/mammalian target of rapamycin (mTOR) pathway mediates cell survival and proliferation and contributes to tumor progression. Soft tissue leiomyosarcoma continues to show poor prognosis, and little is known about its mechanisms of tumor progression. Here the authors investigated the significance of act...

journal_title：Cancer

authors： Setsu N,Yamamoto H,Kohashi K,Endo M,Matsuda S,Yokoyama R,Nishiyama K,Iwamoto Y,Dobashi Y,Oda Y

更新日期：2012-03-15 00:00:00

abstract：:Blood was obtained on 36 occasions from 12 healthy adult volunteers and the polymorphonuclear leukocytes (PMNL) were separated. PMNL hexose monophosphate shunt activity of whole blood and ability of separated cells to phagocytize and kill E. coli were evaluated when the PMNL were incubated with normal pooled sera and ...

journal_title：Cancer

authors： Pickering LK,Ericsson CD,Kohl S

更新日期：1978-10-01 00:00:00

abstract：:The records of 52 patients younger than 40 years of age who had bronchogenic carcinoma diagnosed between 1965 and 1985 were reviewed. The preponderance of adenocarcinoma (54%), the lower male-female ratio in this age group compared with patients age 40 or older (2:1), the importance of cigarette smoking as a causative...

journal_title：Cancer

authors： Jubelirer SJ,Wilson RA

更新日期：1991-03-01 00:00:00

abstract：:A patient developed widely metastatic adenoid cystic carcinoma of the parotid gland after several local recurrences. A complete regression of pleural, pulmonary parenchymal, cutaneous, and bone metastases was seen following therapy with 5-fluorouracil, Adriamycin, and mitomycin C. This is the second complete response ...

journal_title：Cancer

authors： Budd GT,Groppe CW

更新日期：1983-02-15 00:00:00

abstract：BACKGROUND:Patients with prostate cancer receiving androgen deprivation therapy (ADT) are at risk of sleep disturbance; however, to the authors' knowledge, the mechanisms by which ADT may affect sleep are not well understood. The current study compared objective and subjective sleep disturbance in ADT recipients and co...

journal_title：Cancer

authors： Gonzalez BD,Small BJ,Cases MG,Williams NL,Fishman MN,Jacobsen PB,Jim HSL

更新日期：2018-02-01 00:00:00

abstract：BACKGROUND:Breast carcinoma is one of the leading causes of excess mortality rates in Harlem, an inner-city neighborhood with the highest mortality rates and worst life expectancy in New York City. This study reports the results of a breast carcinoma screening and diagnostic program in Harlem. METHODS:Retrospective re...

journal_title：Cancer

authors： Liberman L,Freeman HP,Chandra S,Stein AL,McCord C,Godfrey D,Dershaw DD

更新日期：2002-07-01 00:00:00

abstract：BACKGROUND:Complementary medicine has become an important aspect of palliative cancer care. This overview is primarily aimed at providing guidance to clinicians regarding some commonly used complementary therapies. METHODS:Several complementary therapies were identified as particularly relevant to palliative cancer ca...

journal_title：Cancer

authors： Ernst E

更新日期：2001-06-01 00:00:00

abstract：BACKGROUND:The quality of randomized radiotherapy studies investigating the palliation of painful bone metastases has been questioned, with some authors recognizing the potential impact of bias on result interpretation. However, there has been no published comprehensive evaluation of quality assessment. The goals of th...

journal_title：Cancer

authors： Shakespeare TP,Thiagarajan A,Gebski V

更新日期：2005-05-01 00:00:00

abstract：BACKGROUND:The presence of tumor at the inked margins (IMs) of breast specimens is associated with an increased risk of local recurrence after breast-conserving therapy for invasive breast carcinoma and ductal carcinoma in situ (DCIS). Given the importance of margin status, some have advocated the use of shaved margins...

journal_title：Cancer

authors： Guidi AJ,Connolly JL,Harris JR,Schnitt SJ

更新日期：1997-04-15 00:00:00

abstract：:Four cases of childhood hepatic angiosarcoma (HAS), representing the malignant form of infantile hemangioendothelioma, are described. The morphologic appearance of childhood HAS differs from the adult form in the following features: the associated presence of benign infantile hemangioendothelioma; the presence of dyso...

journal_title：Cancer

authors： Falk H,Herbert JT,Edmonds L,Heath CW Jr,Thomas LB,Popper H

更新日期：1981-01-15 00:00:00

abstract：BACKGROUND:Wild-type p53 protein activates the WAF1/CIP-1 (p21) gene, leading to G1 arrest after DNA damage. The authors investigated the relation of p21 and p53 expression in pancreatic adenocarcinomas to disease stage, overall patient survival, and survival when chemotherapy or radiation therapy was given. METHODS:P...

journal_title：Cancer

authors： Dergham ST,Dugan MC,Joshi US,Chen YC,Du W,Smith DW,Arlauskas P,Crissman JD,Vaitkevicius VK,Sarkar FH

更新日期：1997-08-01 00:00:00

abstract：BACKGROUND:Fas (CD95/APO-1) and Fas ligand (FasL) play key roles in immunologic homeostasis and immune privilege and may regulate normal cell turnover. Earlier studies had suggested that FasL-positive pancreatic carcinoma cell lines can induce apoptosis in T cells, thereby evading host immune surveillance. In the curre...

journal_title：Cancer

authors： Bernstorff WV,Glickman JN,Odze RD,Farraye FA,Joo HG,Goedegebuure PS,Eberlein TJ

更新日期：2002-05-15 00:00:00

abstract：BACKGROUND:Clinical trials established the value of breast-conserving treatment (BCT) including the macroscopic removal of the tumor followed by local radiation therapy (RT) for Stage I and II invasive carcinomas. The occurrence of local tumor recurrence is related to the extent and multifocality of the tumor. Various ...

journal_title：Cancer

authors： Faverly DR,Hendriks JH,Holland R

更新日期：2001-02-15 00:00:00

abstract：:Recent follow-up studies of patients with mammary carcinoma treated with breast-conserving primary radiotherapy identified a triad of pathologic features significantly associated with local treatment failure. These unfavorable characteristics of the primary tumor were: poor or undifferentiated nuclear grade; intraduct...

journal_title：Cancer

authors： Rosen PP,Kinne DW,Lesser M,Hellman S

更新日期：1986-04-01 00:00:00

abstract：:The difficulties encountered in establishing a diagnosis of a malignant peritoneal mesothelioma are emphasized in a patient who developed the lesion 16 years after radiation therapy for a seminoma of the testis. Historically, histologically, electron microscopically, and by microincineration, there was no evidence of ...

journal_title：Cancer

authors： Stock RJ,Fu YS,Carter JR

更新日期：1979-09-01 00:00:00

abstract：BACKGROUND:Well differentiated (WD) and dedifferentiated (DD) retroperitoneal liposarcoma (RPLS) have distinct biologic behaviors. Consequently, the therapeutic approaches for these tumors differ and mandate an accurate preoperative diagnosis. The authors of this report evaluated whether computed tomography (CT) can be...

journal_title：Cancer

authors： Lahat G,Madewell JE,Anaya DA,Qiao W,Tuvin D,Benjamin RS,Lev DC,Pollock RE

更新日期：2009-03-01 00:00:00

abstract：:Over the years, there has been a continuous increase in clinically relevant driver mutations in patients with non-small cell lung cancer (NSCLC). Among these, dysregulated activation of the MET tyrosine kinase receptor has gained importance due to the recent development of quite effective treatments. MET dysregulation...

journal_title：Cancer

authors： Friedlaender A,Drilon A,Banna GL,Peters S,Addeo A

更新日期：2020-11-15 00:00:00

abstract：BACKGROUND:Many studies have tried to identify prognostic factors to guide the selection of patients at high risk for metastases in penile carcinoma. The authors evaluated human papillomavirus (HPV) status with respect to clinical features, incidence of metastases, and prognosis of penile carcinoma. METHODS:Human papi...

journal_title：Cancer

authors： Bezerra AL,Lopes A,Santiago GH,Ribeiro KC,Latorre MR,Villa LL

更新日期：2001-06-15 00:00:00

abstract：:Higher serum iron and ferritin levels noted in hepatitis B antigen (HBAg) carriers than in noncarriers suggests that virus might actively replicate in hepatocytes, stimulate ferritin synthesis, and result in increased liver iron stores. A comparative semiquantitative study of immunohistochemical ferritin (0-12) and he...

journal_title：Cancer

authors： Cohen C,Berson SD,Shulman G,Budgeon LR

更新日期：1985-11-01 00:00:00

abstract：BACKGROUND:The development of novel therapeutic approaches for cancer therapy is important, especially for tumors that have poor response or develop resistance to standard chemotherapy and radiation. We discovered that noninvasive radiofrequency (RF) fields can affect cancer cells but not normal cells, inhibit progress...

journal_title：Cancer

authors： Curley SA,Palalon F,Lu X,Koshkina NV

更新日期：2014-11-01 00:00:00

abstract：:The possibility that urinary pepsinogen I is a tumor marker of stomach cancer after total gastrectomy was examined. To decide the cutoff level of urinary pepsinogen I after total gastrectomy, urine samples from 15 patients who had undergone total gastrectomy for stomach cancer in the early or advanced stages and had b...

journal_title：Cancer

authors： Yamaguchi T,Takahashi T,Yokota T,Kitamura K,Noguchi A,Kamiguchi M,Doi M,Ahn T,Sawai K,Yamane T

更新日期：1991-08-15 00:00:00

abstract：BACKGROUND:Although K-ras is the most frequently mutated protooncogene in colorectal carcinoma, the specific role and timing of K-ras mutations in colorectal carcinogenesis remains controversial. In the current study, the authors investigated associations with K-ras mutation in incident sporadic colorectal adenomas tha...

journal_title：Cancer

authors： Barry EL,Baron JA,Grau MV,Wallace K,Haile RW

更新日期：2006-03-01 00:00:00

abstract：:Carcinoembryonic antigen is only a tumor assoicated antigen and is less clinically useful than the original report suggested. However, the CEA assays in clinical use utilize reagents operationally defined by old criteria. There is now abundant evidence that "CEA" consists of a heterogenous family of related glycoprote...

journal_title：Cancer

authors： Alpert E

更新日期：1978-09-01 00:00:00

abstract：BACKGROUND:The objective of this study was to evaluate the efficacy and toxicity of a high-dose 5-fluorouracil and actinomycin D regimen (the FA regimen) as salvage chemotherapy for patients with high-risk gestational trophoblastic tumors (GTTs). METHODS:From 1985 to 1997, 10 patients with refractory, high-risk GTTs w...

journal_title：Cancer

authors： Matsui H,Suzuka K,Iitsuka Y,Yamazawa K,Tanaka N,Mitsuhashi A,Seki K,Sekiya S

更新日期：2002-09-01 00:00:00

abstract：BACKGROUND:Human epidermal growth factor receptor 2 (HER2) is a therapeutic target in patients with esophageal adenocarcinoma (EAC), with gene amplification used as a selection criterion for treatment, although to the authors' knowledge the concordance between amplification and HER2 protein expression remains undefined...

journal_title：Cancer

authors： Yoon HH,Sukov WR,Shi Q,Sattler CA,Wiktor AE,Diasio RB,Wu TT,Jenkins RB,Sinicrope FA

更新日期：2014-02-01 00:00:00

abstract：BACKGROUND:There is controversy regarding the optimal management of thyroid cancer. The proportion of patients with low-risk thyroid cancer who received radioactive iodine (RAI) treatment increased over the last 20 years, and little is known about the role played by clinicians in hospital-level RAI use for low-risk dis...

journal_title：Cancer

authors： Haymart MR,Banerjee M,Yang D,Stewart AK,Koenig RJ,Griggs JJ

更新日期：2013-01-15 00:00:00

abstract：:A bronchogenic tumor was removed from a 12-year-old girl. Histology showed a clear cell lesion with electron microscope features compatible with serous acinic cell origin. ...

journal_title：Cancer

authors： Katz DR,Bubis JJ

更新日期：1976-08-01 00:00:00

abstract：:The clinicopathologic features and response to therapy of 28 patients with non-Ewing's flat bone sarcoma treated at St. Jude Children's Research Hospital, Memphis, Tennessee, over a 25-year period were reviewed. Twenty-two patients had osteosarcoma, four malignant fibrous histiocytoma, one chondrosarcoma, and one fibr...

journal_title：Cancer

authors： Kellie SJ,Pratt CB,Parham DM,Fleming ID,Meyer WH,Rao BN

更新日期：1990-02-15 00:00:00