Abstract:
:The ultrastructure of a case of intravascular papillary endothelial hyperplasia is presented. The papillae and septa within the lesion showed a similar organization. The surface was lined by a nonstratified layer of plump endothelial cells. Immediately beneath lay cells and processes of pericytes rich in thin filaments with fusiform densities, resembling smooth muscle cells. Primitive mesenchymal cells were observed to lie among the pericytes. The stroma beyond the subendothelial layer was collagenous and contained fibroblasts. The ultrastructure of the cells and their organization closely resembles human granulation tissue.
journal_name
Cancerjournal_title
Cancerauthors
Kreutner A Jr,Smith RM,Trefny FAdoi
10.1002/1097-0142(197811)42:5<2304::aid-cncr282042subject
Has Abstractpub_date
1978-11-01 00:00:00pages
2304-10issue
5eissn
0008-543Xissn
1097-0142journal_volume
42pub_type
杂志文章相关文献
CANCER文献大全abstract::A humoral microcytotoxicity assay has been used to study the immune response to human malignant astrocytic tumors. Two series are described. When the assay was performed under uniform, ideal conditions, the sera from 36 of 45 patients with these tumors (80%) produced significant cytotoxicity against allogeneic astrocy...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(197901)43:1<86::aid-cncr28204301
更新日期:1979-01-01 00:00:00
abstract:BACKGROUND:This study analyzed whether proliferative activity and expression of P-glycoprotein 170 (P-170) or glutathione S-transferase-pi (GST-pi) in human non-small cell lung carcinomas (NSCLC) represent independent factors in resistance to doxorubicin or whether an association exists between these factors. METHODS:...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19920815)70:4<764::aid-cncr28207
更新日期:1992-08-15 00:00:00
abstract:BACKGROUND:Crizotinib is a tyrosine kinase inhibitor active against ALK, MET, and ROS1. We previously reported that crizotinib decreases testosterone in male patients. The detailed etiology of the effect, its symptomatic significance, and the effectiveness of subsequent testosterone replacement have not been previously...
journal_title:Cancer
pub_type: 杂志文章,多中心研究
doi:10.1002/cncr.28089
更新日期:2013-07-01 00:00:00
abstract::We have demonstrated by tissue assay and immunohistochemical techniques that tumor cells appear to be the source of the increased histaminase activity found in 60% of ascitic fluids from patients with ovarian carcinoma. The histaminase activity in 64% of tumor tissues studied was greater than 100 U/g of tissue, a valu...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19800515)45:10<2568::aid-cncr282
更新日期:1980-05-15 00:00:00
abstract::In a study conducted by the Eastern Cooperative Oncology Group, 51 evaluable women with advanced ovarian carcinoma were randomized to either abdominal radiation therapy alone, chlorambucil alone, or to a combination of radiation therapy and chlorambucil by members of the Eastern Cooperative Oncology Group. Provision w...
journal_title:Cancer
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1002/1097-0142(197511)36:5<1625::aid-cncr282036
更新日期:1975-11-01 00:00:00
abstract:BACKGROUND:A phase 2 trial was carried out to assess the antineoplastic activity of 2 courses of cyclophosphamide-etoposide in relapsed osteosarcoma patients. METHODS:Twenty-six relapsed osteosarcoma patients with a median age of 18.5 years (8.3-47.1) were enrolled. Seven patients were in first relapse (27%), 11 in se...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.24368
更新日期:2009-07-01 00:00:00
abstract:BACKGROUND:Although >70% of younger women with nonmetastatic breast cancer (BC) received adjuvant chemotherapy, only approximately 15% to 20% of elderly women with BC received chemotherapy. The decision to treat may be associated with nonmedical factors, such as patient, physician, or practice characteristics. In the c...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.24448
更新日期:2009-09-01 00:00:00
abstract::Forty-three patients with evaluable metastatic breast cancer refractory to hormonal agents and extensive combination chemotherapy including doxorubicin were treated with mitomycin, 20 mg/m2 intravenously every 6 weeks. There were five partial responses (12%) and three minor responses (7%), with a mean time to progress...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19851115)56:10<2381::aid-cncr282
更新日期:1985-11-15 00:00:00
abstract:BACKGROUND:Cetuximab in combination with docetaxel was examined in chemotherapy-refractory/resistant patients with advanced nonsmall-cell lung cancer (NSCLC) to determine response rate, survival, safety, and pharmacokinetics (PK). METHODS:Patients had evidence of epidermal growth factor receptor (EGFR) expression (> o...
journal_title:Cancer
pub_type: 杂志文章,多中心研究
doi:10.1002/cncr.24148
更新日期:2009-04-15 00:00:00
abstract::A leukocyte migration procedure was utilized to test cellular hypersensitivity of breast cancer patients' leukocytes to autologous and homologous breast cancer tissues and to murine milk containing murine mammary tumor virus (MuMTV). The in vitro responsiveness of the leukocytes and the antigenicity of breast cancer t...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(197501)35:1<121::aid-cncr2820350
更新日期:1975-01-01 00:00:00
abstract:BACKGROUND:The balance among cell proliferation, cell differentiation, and cell death determines the cell number in a population as well as the size or even the stage of a tumor. Thus, to improve our understanding of the pathogenesis of neoplasms, it is important to investigate the regulation of both cell proliferation...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/(sici)1097-0142(19980615)82:12<2373::aid-c
更新日期:1998-06-15 00:00:00
abstract:BACKGROUND:A review of the literature indicated variable underestimation rates for breast core-needle biopsy (CNB) based on generally small series. In this article, the authors present precise estimates for overall underestimation and for categories of histologic underestimates (including categories that reflect contem...
journal_title:Cancer
pub_type: 杂志文章,meta分析
doi:10.1002/cncr.22435
更新日期:2007-02-01 00:00:00
abstract::Nuclear DNA content of paraffin-embedded tissue from 48 adrenocortical neoplasms, 18 histologically normal control adrenal glands, and five hyperplastic adrenal glands was analyzed retrospectively using flow cytometry. Aneuploidy was compared with morphologic criteria as a predictor of recurrence. All 18 controls, fiv...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19870615)59:12<2091::aid-cncr282
更新日期:1987-06-15 00:00:00
abstract:BACKGROUND:Controlled-release (CR) morphine tablets have become routine therapy in the management of cancer pain. Compared with immediate-release (IR) morphine, this formulation provides the benefit of dosing every 12 hours. METHODS:This study reviewed the 10 published, well controlled, repeated-dose, comparative stud...
journal_title:Cancer
pub_type: 杂志文章,评审
doi:10.1002/(sici)1097-0142(19980615)82:12<2299::aid-c
更新日期:1998-06-15 00:00:00
abstract::Conjugal tumors are rarely reported; but nevertheless, raise important questions of possible etiologic factors. In this report, the presentation of grade 2 gemistocytic astrocytomas in an unrelated married couple in their early thirties within 18 months of each other is described. In both cases the left frontal region...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19850215)55:4<864::aid-cncr28205
更新日期:1985-02-15 00:00:00
abstract:BACKGROUND:Forty-eight patients with resected Stages IIA and IIB melanoma were immunized with two tumor antigen epitope peptides derived from gp100(209-217) (210M) (IMDQVPSFV) and tyrosinase(368-376) (370D) (YMDGTMSQV) emulsified with incomplete Freund's adjuvant (IFA). Patients were assigned randomly to receive either...
journal_title:Cancer
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1002/cncr.11045
更新日期:2003-01-01 00:00:00
abstract::This presentation will focus on the issues of access to care, insurance, and personpower in pediatric oncology. The invitation to participate in this workshop was addressed to me as former Chairman of the Section of Hematology/Oncology of the American Academy of Pediatrics and current Chairman of the sub-board of Pedi...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19930515)71:10+<3290::aid-cncr28
更新日期:1993-05-15 00:00:00
abstract:BACKGROUND:It remains controversial whether modified radical neck dissection (MRND) for patients with papillary thyroid carcinoma improves prognosis. However, it is highly probable that the incidence of local recurrence is reduced by lymph node dissection. Sentinel lymph node (SLN) biopsy (SLNB) for patients with melan...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(20011201)92:11<2868::aid-cncr101
更新日期:2001-12-01 00:00:00
abstract::Acute non-lymphocytic leukemia occurred in eight women following long-term treatment with Treosulfan (= dihydroxybusulfan) for ovarian carcinoma. The leukemia developed from 21 to 58 months (median 50 months) after the institution of chemotherapy. At the time when the leukemia appeared seven of the patients were in co...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19800101)45:1<19::aid-cncr282045
更新日期:1980-01-01 00:00:00
abstract::Twenty-two patients with cancer of the colon and rectum were studied: preoperative and postoperative cell-mediated and humoral immune factors were assessed, and local concentration of immunoglobulins in tumor tissue and in normal mucosa were measured. Lymphocyte function was found to be reduced in 50% of stage A and B...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19800815)46:4<700::aid-cncr28204
更新日期:1980-08-15 00:00:00
abstract::The clinical, morphologic, and immunohistochemical features of 5 cases of peripheral T-cell lymphoma with lymph node and skin involvement are reported. All patients were male and presented with generalized lymphadenopathy and skin lesions. Lymph node biopsy specimens showed a diffusely growing, pleomorphic, atypical l...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19850415)55:8<1714::aid-cncr2820
更新日期:1985-04-15 00:00:00
abstract::Twenty-eight peritoneovenous shunts were placed to relieve ascites in 26 patients with a variety of underlying malignancies. Nine of the patients had documented liver metastases and hyperbilirubinemia. Severe thrombocytopenia with laboratory evidence of disseminated intravascular coagulation (DIC) occurred in four of ...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19850601)55:11<2718::aid-cncr282
更新日期:1985-06-01 00:00:00
abstract::This study examines the interrelationships of depth of penetration, tumor size, and the number of positive nodes in Dukes C colorectal cancer. The results indicated that depth of tumor penetration was related to both tumor size and the number of positive regional lymph nodes. Tumors with positive nodes which failed to...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19840615)53:12<2707::aid-cncr282
更新日期:1984-06-15 00:00:00
abstract::Cases of systemic lupus erythematosus, systemic sclerosis, periarteritis nodosa, and dermato- and polymyositis autopsied in Japan during a recent, 7-year period (1972-1978) were studied to assess the incidence of cancer as a complication. In comparison with the other three groups, cases of dermato- and polymyositis (D...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19841101)54:9<1841::aid-cncr2820
更新日期:1984-11-01 00:00:00
abstract:BACKGROUND:Clinical practice guidelines for the management of breast carcinoma were introduced in Australia in October, 1995. This article describes the management of early-stage breast carcinoma both before and after the introduction of these guidelines. METHODS:All cases of early breast carcinoma that were diagnosed...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.20401
更新日期:2004-08-01 00:00:00
abstract:BACKGROUND:Cognitive dysfunction experienced by individuals with cancer represents an important survivorship issue because of its potential to affect occupational, scholastic, and social activities. Whereas early efforts to characterize cognitive dysfunction primarily focused on the effects of chemotherapy, more recent...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.25298
更新日期:2011-01-01 00:00:00
abstract::The role of amsacrine in inducing remission in patients with cardiac disease and acute leukemia was evaluated. There were 17 patients with acute myelogenous leukemia (AML), six with acute lymphocytic leukemia (ALL), and one with biphenotypic leukemia. In this series of 24 patients whose disease had relapsed and who ha...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19910915)68:6<1198::aid-cncr2820
更新日期:1991-09-15 00:00:00
abstract:BACKGROUND:Genomic testing is increasingly performed in oncology, but concerns remain regarding the clinician's ability to interpret results. In the current study, the authors sought to determine the agreement between physicians and genomic annotators from the Precision Oncology Decision Support (PODS) team at The Univ...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.31112
更新日期:2018-03-01 00:00:00
abstract:BACKGROUND:Current salvage therapy for recurrent high-risk neuroblastoma is rarely curative. Assessment of the effectiveness of new, primarily cytostatic agents requires the redefinition of study endpoints to reflect disease stabilization rather than tumor response or regression. The intervals of disease control in the...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.23507
更新日期:2008-06-15 00:00:00
abstract::Sixty-two patients with breast cancer treated with Adriamycin-containing adjuvant chemotherapy developed recurrent disease. Four patients refused to take any form of systemic therapy at the time of relapse. Fifty-eight patients were managed with various treatment modalities, and of these 33 (57%) achieved on objective...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19810615)47:12<2798::aid-cncr282
更新日期:1981-06-15 00:00:00