Phase 2 trial of two courses of cyclophosphamide and etoposide for relapsed high-risk osteosarcoma patients.

abstract：:A spontaneous complete remission of 34 months' duration was observed in an adult patient with acute myeloblastic leukemia. The remission occurred after a severe febrile pneumonia, which was treated with leukocyte transfusions. At relapse, chromosomal abnormalities reappeared slowly. Such spontaneous complete remission...

journal_title：Cancer

authors： Ifrah N,James JM,Viguie F,Marie JP,Zittoun R

更新日期：1985-09-01 00:00:00

abstract：:In malignant melanoma, using Sephadex G-200 chromatography and polyacrylamide gel electrophoresis (PAGE), it has been possible to separate two types of skin reactive antigens. The first, found in Sephadex fraction II and PAGE region a appears specific for melanoma. Allogeneic extracts have produced positive reactions ...

journal_title：Cancer

authors： Hollinshead AC

更新日期：1975-10-01 00:00:00

abstract：BACKGROUND:We previously reported that a single prostate-specific antigen (PSA) measured at ages 44-50 was highly predictive of subsequent prostate cancer diagnosis in an unscreened population. Here we report an additional 7 years of follow-up. This provides replication using an independent data set and allows estimate...

journal_title：Cancer

authors： Lilja H,Cronin AM,Dahlin A,Manjer J,Nilsson PM,Eastham JA,Bjartell AS,Scardino PT,Ulmert D,Vickers AJ

更新日期：2011-03-15 00:00:00

abstract：:Between 1968 and 1985, 28 patients with recurrent gestational trophoblastic disease (GTD) were treated at the Southeastern Regional Trophoblastic Disease Center. Sixteen patients received primary therapy at this center and had recurrence diagnosed by re-elevation of human chorionic gonadotropin (hCG) levels after thre...

journal_title：Cancer

authors： Mutch DG,Soper JT,Babcock CJ,Clarke-Pearson DL,Hammond CB

更新日期：1990-09-01 00:00:00

abstract：BACKGROUND:The clinical relevance of DNA image cytometry (ICM) and flow cytometry (FCM) remains under investigation in breast carcinoma. The objective of the current work was to study the prognostic value of DNA ICM and FCM in a series of patients randomized in a control trial. A multivariate analysis has been performe...

journal_title：Cancer

authors： Mandard AM,Denoux Y,Herlin P,Duigou F,van De Vijver MJ,Clahsen PC,van Den Broek L,Sahmoud TM,Henry-Amar M,van De Velde CJ

更新日期：2000-10-15 00:00:00

abstract：BACKGROUND:Angiogenesis in individuals with various solid tumors has provided useful information on tumor progression and prognosis, and many examples of mast cell (MC) accumulation coupled with angiogenesis can be found in the literature. METHODS:Utilizing monoclonal antibodies for tryptase that are specific markers ...

journal_title：Cancer

authors： Takanami I,Takeuchi K,Naruke M

更新日期：2000-06-15 00:00:00

abstract：BACKGROUND:The antitumor activity of the chemical conjugate and recombinant forms of the mitotoxin basic fibroblast growth factor (bFGF) saporin (SAP) and the bFGF receptor-directed immunotoxin 11A8-SAP against human ovarian teratocarcinoma PA-1 was examined in athymic nude mice. Alternative administration schedules to...

journal_title：Cancer

authors： Davol P,Beitz JG,Mohler M,Ying W,Cook J,Lappi DA,Frackelton AR Jr

更新日期：1995-07-01 00:00:00

abstract：BACKGROUND:Tyrosine kinase inhibitors (TKIs) have improved the outcome of patients with gastrointestinal stromal tumors (GISTs), but most patients eventually develop resistance and progress. Dasatinib is a potent inhibitor of BCR-ABL, KIT, and SRC family kinases as well as imatinib-resistant cells. In GISTs, response e...

journal_title：Cancer

authors： Montemurro M,Cioffi A,Dômont J,Rutkowski P,Roth AD,von Moos R,Inauen R,Toulmonde M,Burkhard RO,Knuesli C,Bauer S,Cassier P,Schwarb H,Le Cesne A,Koeberle D,Bärtschi D,Dietrich D,Biaggi C,Prior J,Leyvraz S

更新日期：2018-04-01 00:00:00

abstract：BACKGROUND:Immediate or early postmastectomy breast reconstruction is performed infrequently. To the authors' knowledge, little is known regarding surgeon or patient perspectives on reconstruction treatment decisions. The purpose of the current study was to identify patient attitudes and preferences associated with bre...

journal_title：Cancer

authors： Morrow M,Mujahid M,Lantz PM,Janz NK,Fagerlin A,Schwartz K,Liu L,Deapen D,Salem B,Lakhani I,Katz SJ

更新日期：2005-12-01 00:00:00

abstract：BACKGROUND:Colorectal cancer (CRC) is the third most common cause of cancer deaths; however, rates of regular screening for this cancer are low. A quality improvement (QI) program to increase CRC screening was developed for use in a managed care health plan. METHODS:Thirty-six provider organizations (POs) contracting ...

journal_title：Cancer

authors： Ganz PA,Farmer MM,Belman MJ,Garcia CA,Streja L,Dietrich AJ,Winchell C,Bastani R,Kahn KL

更新日期：2005-11-15 00:00:00

abstract：:Methionine-depleting total parenteral nutrition (methionine-depleting TPN), which infuses an amino acid solution devoid of L-methionine and L-cysteine as the sole protein source, showed enhancement of the effect of several anti-cancer agents. In this study, the combined effect of the methionine-depleting TPN with the ...

journal_title：Cancer

authors： Goseki N,Yamazaki S,Endo M,Onodera T,Kosaki G,Hibino Y,Kuwahata T

更新日期：1992-04-01 00:00:00

abstract：:Primary malignant lymphomas of the breast (PBL) are uncommon. The authors report the clinical, histologic, and immunoperoxidase findings on 20 cases recorded at the Alberta Cancer Registry over the last 23 years. These cases were then added to material on 257 cases abstracted from the literature and analyzed. It was f...

journal_title：Cancer

authors： Hugh JC,Jackson FI,Hanson J,Poppema S

更新日期：1990-12-15 00:00:00

abstract：BACKGROUND:Cancer cell expression of costimulatory molecule B7-H1 has been implicated as a potent inhibitor of T-cell-mediated antitumoral immunity. The authors recently reported that B7-H1 is aberrantly expressed in primary renal cell carcinoma (RCC). Blockade of B7-H1, as demonstrated in several murine cancer models,...

journal_title：Cancer

authors： Thompson RH,Gillett MD,Cheville JC,Lohse CM,Dong H,Webster WS,Chen L,Zincke H,Blute ML,Leibovich BC,Kwon ED

更新日期：2005-11-15 00:00:00

abstract：:The concept of second-look surgery was introduced by Wangensteen 25 years ago, and 17% of patients were reported to be converted to a cancer-free state. Instead of an arbitrary time interval for reoperation, serial CEA values were used as the indicator of colon cancer recurrence and second-look operation. Twenty-two r...

journal_title：Cancer

authors： Minton JP,Martin EW Jr

更新日期：1978-09-01 00:00:00

abstract：:The current classification of cutaneous malignant lymphomas (ML) into low-grade and high-grade lymphomas was found to be of limited reproducibility and permitted only a rough prediction about outcome. With this in mind, the relationship between nuclear DNA content and both prognosis and histologic grading according to...

journal_title：Cancer

authors： Vogt T,Stolz W,Braun-Falco O,Kaudewitz P,Eckert F,Abmayr W,Dummer R,Burg G

更新日期：1991-09-01 00:00:00

abstract：BACKGROUND:Patients undergoing allogeneic hematopoietic stem cell transplantation (HSCT) for chronic myeloid leukemia (CML) are increasingly likely to have received a novel tyrosine kinase inhibitor (NTKI) after failing imatinib mesylate. It is unknown whether the use of these NTKIs before HSCT increases transplant-rel...

journal_title：Cancer

authors： Jabbour E,Cortes J,Kantarjian H,Giralt S,Andersson BS,Giles F,Shpall E,Kebriaei P,Champlin R,de Lima M

更新日期：2007-07-15 00:00:00

abstract：BACKGROUND:Atypical and anaplastic meningiomas tend to recur and to invade adjacent brain, bone, and skin. They also can metastasize to extracranial organs such as the lung, liver, or bone, causing death. Recent reports have indicated that allelic deletion of chromosome 1p is associated with malignant progression of me...

journal_title：Cancer

authors： Ishino S,Hashimoto N,Fushiki S,Date K,Mori T,Fujimoto M,Nakagawa Y,Ueda S,Abe T,Inazawa J

更新日期：1998-07-15 00:00:00

abstract：BACKGROUND:Although caspase recruitment domain (CARD) membrane-associated guanylate kinase (MAGUK) protein 1 (CARMA1) and CARD9 play important roles in lymphocyte activation, the significance of CARMA1 and CARD9 in the pathogenesis of gastric mucosa-associated lymphoid tissue (MALT) lymphoma remains to be elucidated. ...

journal_title：Cancer

authors： Nakamura S,Nakamura S,Matsumoto T,Yada S,Hirahashi M,Suekane H,Yao T,Goda K,Iida M

更新日期：2005-11-01 00:00:00

abstract：:The first three well-documented cases of pure, extraskeletal telangiectatic osteosarcoma of the soft tissues are presented in this article. The distinctive gross features were a predominance of large, blood-filled spaces, which, on histologic examination, were large blood-filled cavities in association with cyst-like ...

journal_title：Cancer

authors： Mirra JM,Fain JS,Ward WG,Eckardt JJ,Eilber F,Rosen G

更新日期：1993-05-15 00:00:00

abstract：BACKGROUND:Idarubicin, a new anthracycline analogue, is available in an oral preparation, and responses have been observed using relatively aggressive therapy in patients with myelodysplastic syndromes (MDS). The authors studied whether a chronic low-dose schedule would be effective but less myelotoxic. METHODS:Forty-...

journal_title：Cancer

authors： Greenberg BR,Reynolds RD,Charron CB,Squillace KM,Lessin LS,Case DC Jr,Gams RA

更新日期：1993-03-15 00:00:00

abstract：:A case of transfusion-induced graft-versus-host disease (GVHD) occurring in a 31-year-old female with Hodgkin's disease in complete remission is reported. Clinical features are similar to 19 other reported cases of transfusion-induced GVHD associated with malignant lymphoma. The lack of relationship with underlying hi...

journal_title：Cancer

authors： Spitzer TR,Cahill R,Cottler-Fox M,Treat J,Sacher R,Deeg HJ

更新日期：1990-12-01 00:00:00

abstract：BACKGROUND:Although Kaposi sarcoma (KS) initially was described over a century ago, its biology remains enigmatic and conflicting. Whereas the classic type occurs mainly in older men of Mediterranean or Eastern European backgrounds and is not linked to impairment of the host immune response, iatrogenic and human immuno...

journal_title：Cancer

authors： Iscovich J,Boffetta P,Franceschi S,Azizi E,Sarid R

更新日期：2000-02-01 00:00:00

abstract：BACKGROUND:Radiation recall is a recurrence of acute toxicity within a previously quiescent radiation field that occurs with subsequent administration of chemotherapy. METHODS:A patient with acquired immune deficiency syndrome (AIDS)-related Kaposi sarcoma (KS) who had radiation recall is reported. The patient was par...

journal_title：Cancer

authors： Stelzer KJ,Griffin TW,Koh WJ

更新日期：1993-02-15 00:00:00

abstract：BACKGROUND:Despite the widespread use of Papanicolaou (Pap) smear screening, substantial morbidity and mortality from cervical carcinoma continue in the U.S. Although access to screening is a major barrier to use of the Pap smear, invasive cervical carcinoma (ICC) still is observed in health plan members who have compr...

journal_title：Cancer

authors： Sung HY,Kearney KA,Miller M,Kinney W,Sawaya GF,Hiatt RA

更新日期：2000-05-15 00:00:00

abstract：:Twenty-eight peritoneovenous shunts were placed to relieve ascites in 26 patients with a variety of underlying malignancies. Nine of the patients had documented liver metastases and hyperbilirubinemia. Severe thrombocytopenia with laboratory evidence of disseminated intravascular coagulation (DIC) occurred in four of ...

journal_title：Cancer

authors： Tempero MA,Davis RB,Reed E,Edney J

更新日期：1985-06-01 00:00:00

abstract：BACKGROUND:Radiotherapy (RT) plays a major role in the management of hemangiopericytomas (HAP). The present analysis evaluates the role of precision RT in the management of HAP of the central nervous system (CNS) and represents one of the largest series of HAP treated with RT that can be found in the literature. METHO...

journal_title：Cancer

authors： Combs SE,Thilmann C,Debus J,Schulz-Ertner D

更新日期：2005-12-01 00:00:00

abstract：:Five hundred forty three adult patients with acute leukemia were entered on the study designed to: (1) test efficacy of vincristine and prednisone used as primary drug therapy in patients with good prognosis as judged by a circulating blast cell count less than 30,000 cm2; (2) investigate the use of either simultaneou...

journal_title：Cancer

authors： McCredie KB,Gehan EA,Freireich EJ,Hewlett JS,Coltman CA Jr,Hussein KK,Balcerzak SP,Chen TT

更新日期：1983-09-15 00:00:00

abstract：:Forty-three patients with widely metastatic melanoma were studied. Visceral metastases were present in 79% of the patient group, including five patients with brain metastases. No patients were excluded because of "early death," etc., from analysis. All 43 patients received 24-hour DTIC infusions. Dosages for individua...

journal_title：Cancer

authors： Thatcher N,Anderson H,James R,Davenport P,Craig P

更新日期：1986-06-01 00:00:00

abstract：BACKGROUND:The authors hypothesized that the outcomes for young patients who present with primary osteosarcoma of flat bones or secondary osteosarcoma after other primary malignancies are similar because the sites of these tumors rarely makes them amenable to complete surgical resection. METHODS:The authors reviewed t...

journal_title：Cancer

authors： Pratt CB,Meyer WH,Rao BN,Pappo AS,Fleming ID,Luo X,Cain A,Kaste SC,Shearer PD,Jenkins JJ 3rd

更新日期：1997-09-15 00:00:00

abstract：BACKGROUND:Sixty cases of axillary metastases from clinically occult breast cancer were analyzed. All cases had histologic evidence of metastatic nodes compatible with breast carcinoma. METHODS:Thirty-three patients underwent breast surgery at the time of histologic diagnosis of the axillary metastases, 6 patients wer...

journal_title：Cancer

authors： Merson M,Andreola S,Galimberti V,Bufalino R,Marchini S,Veronesi U

更新日期：1992-07-15 00:00:00