Prediction of significant prostate cancer diagnosed 20 to 30 years later with a single measure of prostate-specific antigen at or before age 50.

abstract：:Despite the fact that expression of Fas ligand (FasL) in cytotoxic T lymphocytes (CTLs) and in natural killer (NK) cells plays an important role in Fas-mediated tumor killing, During tumor progression FasL-expressing tumor cells are involved in counterattacking to kill tumor-infiltrating lymphocytes (TILs). Soluble Fa...

journal_title：Cancer

authors： Kim R,Emi M,Tanabe K,Uchida Y,Toge T

更新日期：2004-06-01 00:00:00

abstract：BACKGROUND:The ThinPrep Pap Test (TP), a liquid-based cervical cytology preparation, was approved for use in the U.S. in 1996. The purpose of this study was to compare TP performance and biopsy follow-up studies with a similar population of high risk patients sampled by conventional Papanicolaou (Pap) smear (CS). METH...

journal_title：Cancer

authors： Carpenter AB,Davey DD

更新日期：1999-06-25 00:00:00

abstract：BACKGROUND:Helicobacter pylori recently was identified as a risk factor for gastric cancer. Its association with preneoplastic conditions of the stomach, however, is undocumented. METHODS:Gastric biopsy specimens from 245 symptomatic patients were examined for neoplastic and preneoplastic lesions and for gastric H. py...

journal_title：Cancer

authors： Guarner J,Mohar A,Parsonnet J,Halperin D

更新日期：1993-01-15 00:00:00

abstract：BACKGROUND:Traditional single-marker and multimarker molecular profiling approaches in bladder cancer do not account for major risk factors and their influence on clinical outcome. This study examined the prognostic value of molecular alterations across all disease stages after accounting for clinicopathological factor...

journal_title：Cancer

authors： Mitra AP,Castelao JE,Hawes D,Tsao-Wei DD,Jiang X,Shi SR,Datar RH,Skinner EC,Stein JP,Groshen S,Yu MC,Ross RK,Skinner DG,Cortessis VK,Cote RJ

更新日期：2013-02-15 00:00:00

abstract：:A study of the effects of local tumor radiation alone (1500R) and cyclophosphamide alone (150 mg/kg) on the experimental solid tumor rat hepatoma 3924A has been completed. Cyclophosphamide was more effective in controlling tumor growth than either radiation or 5-fluorouracil (5-FU) (150 mg/kg) previously reported. Par...

journal_title：Cancer

authors： Looney WB,Hopkins HA,Grover WH,Macleod MS,Ritenour ER,Hobson AS

更新日期：1980-06-01 00:00:00

abstract：:Responding to growing concerns regarding the safety, quality, and efficacy of cancer care in the United States, the Institute of Medicine (IOM) of the National Academy of Sciences commissioned a comprehensive review of cancer care delivery in the US health care system in the late 1990s. The National Cancer Policy Boar...

journal_title：Cancer

authors： Spinks T,Albright HW,Feeley TW,Walters R,Burke TW,Aloia T,Bruera E,Buzdar A,Foxhall L,Hui D,Summers B,Rodriguez A,Dubois R,Shine KI

更新日期：2012-05-15 00:00:00

abstract：BACKGROUND:Several studies have demonstrated that abnormal levels of nuclear matrix protein 22 (NMP22) are associated with bladder cancer and have led to the approval of NMP22 as a urinary biomarker by the US Food and Drug Administration. Nonetheless, the clinical significance of NMP22 remains unclear. The objective of...

journal_title：Cancer

authors： Shariat SF,Savage C,Chromecki TF,Sun M,Scherr DS,Lee RK,Lughezzani G,Remzi M,Marberger MJ,Karakiewicz PI,Vickers AJ

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND:The purpose of this study was to assess prostate carcinoma detection and discrimination of benign from malignant prostate tissue with contrast-enhanced ultrasonography. METHODS:In all, 301 subjects referred for prostate biopsy were evaluated with contrast-enhanced sonography using continuous harmonic imagin...

journal_title：Cancer

authors： Halpern EJ,Ramey JR,Strup SE,Frauscher F,McCue P,Gomella LG

更新日期：2005-12-01 00:00:00

abstract：BACKGROUND:Prostate carcinoma metastasizes frequently to the skeleton, causing significant morbidity, particularly severe bone pain. Metastatic lesions typically are osteosclerotic, but there is experimental, histologic, and biochemical evidence of increased bone resorption. Furthermore, bone resorption rates appear to...

journal_title：Cancer

authors： Papapoulos SE,Hamdy NA,van der Pluijm G

更新日期：2000-06-15 00:00:00

abstract：:The combination of conservation surgery and radiation therapy for early breast cancer is gaining acceptance as an alternative to radical mastectomy. This article reviews the results of randomized trials showing that there is no advantage to a radical mastectomy in patients with early breast cancer. In addition, the ar...

journal_title：Cancer

authors： Montague ED,Ames FC,Schell SR,Romsdahl MM

更新日期：1984-12-01 00:00:00

abstract：BACKGROUND:To evaluate the hearing preservation rate and to determine its prognostic factors after gamma knife (GK) stereotactic radiosurgery (SRS) in patients with vestibular schwannoma, the authors used a prospective study design to analyze these patients. METHODS:Between December 1997 and January 2002, 25 patients ...

journal_title：Cancer

authors： Paek SH,Chung HT,Jeong SS,Park CK,Kim CY,Kim JE,Kim DG,Jung HW

更新日期：2005-08-01 00:00:00

abstract：:The cases of three patients with primary carcinoid tumor of the testis were reported. The patients were 41, 44, and 83 years of age. At initial examination, all three had testicular masses with or without associated pain, and none had the carcinoid syndrome. The tumors measured 4.3 cm, 3.0 cm, and 6.5 cm in dimension....

journal_title：Cancer

authors： Zavala-Pompa A,Ro JY,el-Naggar A,Ordóñez NG,Amin MB,Pierce PD,Ayala AG

更新日期：1993-09-01 00:00:00

abstract：BACKGROUND:The psychological adaptation to a cancer diagnosis is characterized by significant distress. Although distress levels in cancer patients have been reported to be the highest shortly after diagnosis and before treatment, few attempts have been made to study emotional adjustment during the diagnostic period of...

journal_title：Cancer

authors： Perczek RE,Burke MA,Carver CS,Krongrad A,Terris MK

更新日期：2002-06-01 00:00:00

abstract：:Available information suggests that individuals with breast cancer gain weight during adjuvant treatment and that this weight gain may be associated with poor prognosis. Exploration of the factors which affect weight gain may aid in developing weight control interventions for these patients. To determine the factors w...

journal_title：Cancer

authors： Levine EG,Raczynski JM,Carpenter JT

更新日期：1991-04-01 00:00:00

abstract：:Preclinical and clinical studies suggest interferons and interferon inducers have antitumor activity for breast carcinoma. Observations include inhibition of growth of freshly derived and continuously passaged breast carcinoma cells in vitro, decreased tumor size and increased survival in spontaneous mouse mammary car...

journal_title：Cancer

authors： Borden EC,Balkwill FR

更新日期：1984-02-01 00:00:00

abstract：:Human papillomavirus (HPV) causes greater than 5% of cancers worldwide, including all cervical cancers and an alarmingly increasing proportion of oropharyngeal cancers (OPCs). Despite markedly reduced cervical cancer incidence in industrialized nations with organized screening programs, cervical cancer remains the sec...

journal_title：Cancer

authors： Berman TA,Schiller JT

更新日期：2017-06-15 00:00:00

abstract：BACKGROUND:Cancer rates in immigrant populations are frequently found to be intermediate between the country of origin and the adopted country. Such observations play an important role in establishing the environmental origin of cancer. Chinese now constitute the third largest group immigrating to New York City. METHO...

journal_title：Cancer

authors： Stellman SD,Wang QS

更新日期：1994-02-15 00:00:00

abstract：:The multiple classifications of histiocytic disorders, and the lack of specificity in their application, have degraded the utility of such diagnostic terms as "Letterer-Siwe Disease" and "Malignant Histiocytosis". A case is presented of a systemic histiocytic proliferation with erythrophagocytosis and giant-cell forma...

journal_title：Cancer

authors： Wolfson WL,Gossett T,Pagani J

更新日期：1976-12-01 00:00:00

abstract：BACKGROUND:CD133 is a specific surface marker for bone marrow-derived circulating endothelial progenitors, which are vital in postnatal physiologic and pathologic (eg, tumor) angiogenesis. In this study, the authors examined whether increased levels of expression of CD133 messenger RNA (mRNA) in peripheral blood predic...

journal_title：Cancer

authors： Lin EH,Hassan M,Li Y,Zhao H,Nooka A,Sorenson E,Xie K,Champlin R,Wu X,Li D

更新日期：2007-08-01 00:00:00

abstract：BACKGROUND:A residual mediastinal mass after treatment represents a common diagnostic problem in the management of patients with Hodgkin lymphoma (HD). Conventional diagnostic radiology, computed tomography (CT), or ultrasonography (US) do not adequately reflect changes as fibrosis or necrosis. Gallium-67 (67Ga) imagin...

journal_title：Cancer

authors： Gasparini MD,Balzarini L,Castellani MR,Tesoro Tess JD,Maffioli LS,Petrillo R,Ceglia E,Musumeci R,Buraggi GL

更新日期：1993-07-15 00:00:00

abstract：BACKGROUND:Central nervous system (CNS) recurrence is almost invariably fatal in patients with aggressive non-Hodgkin lymphoma (NHL). Although some protocols are intended to prevent CNS disease, the value of CNS prophylaxis in patients with aggressive NHL remains to be determined. METHODS:We retrospectively analyzed a...

journal_title：Cancer

authors： Tomita N,Kodama F,Kanamori H,Motomura S,Ishigatsubo Y

更新日期：2002-08-01 00:00:00

abstract：:Between March 1973, and December 1976, 22 patients who developed disease progression during or after MOPP therapy were treated with a new combination, B-CAVe (Bleomycin 5 mg/m2 iv days 1, 28, 35; CCNU 100 mg/m2 po day 1; adriamycin 60 mg/m2 iv day 1; and vinblastine 5 mg/m2 iv day 1). Objective responses were achieved...

journal_title：Cancer

authors： Porzig KJ,Portlock CS,Robertson A,Rosenberg SA

更新日期：1978-05-01 00:00:00

abstract：BACKGROUND:Proliferating cell nuclear antigen (PCNA) is an intranuclear protein that is linked closely to the cell cycle. An immunohistochemical study was performed on the expression of PCNA in various sized hepatocellular carcinomas (HCCs) to determine the relation between the proliferative activity of cancer cells an...

journal_title：Cancer

authors： Suehiro T,Matsumata T,Itasaka H,Yamamoto K,Kawahara N,Sugimachi K

更新日期：1995-08-01 00:00:00

abstract：BACKGROUND:The purpose of this article was to evaluate the utility of a pharmacokinetically modeled measure of regional contrast access, based on dynamic contrast-enhanced magnetic resonance imaging (MRI) studies after preoperative chemotherapy, as a predictor of disease free survival in osteosarcoma. METHODS:The kine...

journal_title：Cancer

authors： Reddick WE,Wang S,Xiong X,Glass JO,Wu S,Kaste SC,Pratt CB,Meyer WH,Fletcher BD

更新日期：2001-06-15 00:00:00

abstract：:To investigate the utility of thallium 201 (Tl-201) thyroid scintigraphy for the detection of thyroid malignancies, early and delayed Tl-201 scintigraphy was done in 70 consecutive patients with a clinically solitary cold (Iodine 123 [I-123]) nodule. Early Tl-201 scintigraphy had a sensitivity of 100% and a specificit...

journal_title：Cancer

authors： Bleichrodt RP,Vermey A,Piers DA,de Langen ZJ

更新日期：1987-12-01 00:00:00

abstract：BACKGROUND:The effects of relaxin (RLX) on the human breast adenocarcinoma cell line MCF-7 have been evaluated. METHODS:The cells were maintained in culture with Dulbecco's modified Eagle's medium with 1% and 10% fetal calf serum. Highly purified porcine RLX was added at concentrations ranging between 10(-11) and 10(-...

journal_title：Cancer

authors： Bigazzi M,Brandi ML,Bani G,Sacchi TB

更新日期：1992-08-01 00:00:00

abstract：:During the past eight years, 137 patients with mycosis fungoides were given total skin electron beam therapy (TSEB) using 2.5 to 4 MeV electrons. A single treatment delivers 400 rads to the entire skin surface, and patients are treated once a week for six to eight consecutive weeks. All have been followed for a median...

journal_title：Cancer

authors： Nisce LZ,Safai B,Kim JH

更新日期：1981-03-01 00:00:00

abstract：BACKGROUND:Skin cancer affects more Americans than any other type of cancer. Children are prime targets for prevention education, because sun overexposure in early childhood may affect the development of skin cancer later in life. Preventive behaviors adopted early in life may be less resistant to change than those acq...

journal_title：Cancer

authors： Loescher LJ,Buller MK,Buller DB,Emerson J,Taylor AM

更新日期：1995-01-15 00:00:00

abstract：:The clinical experience and technologic improvements of the past 40 years are briefly summarized in terms of their contributions to the present optimistic and aggressive approach to the treatment of malignant lymphoma. The reasoning behind the large-field moderately high-dose technique that has evolved is reviewed and...

journal_title：Cancer

authors： Nobler MP

更新日期：1968-10-01 00:00:00

abstract：BACKGROUND:Colonoscopy is the most widely used colorectal cancer (CRC) screening test in the United States. Through the detection and removal of potentially precancerous polyps, it can prevent CRC. However, CRC screening remains low among adults who are recommended for screening. The New Hampshire Colorectal Cancer Scr...

journal_title：Cancer

authors： Rice K,Sharma K,Li C,Butterly L,Gersten J,DeGroff A

更新日期：2019-02-15 00:00:00