Conservation surgery and irradiation as an alternative to mastectomy in the treatment of clinically favorable breast cancer.

abstract：BACKGROUND:The outcome of surgical treatment for early gastric cancer (EGC) generally is considered to be satisfactory. Although a small percentage of patients experience disease recurrence, the absolute number of such instances is too small for assessment of risk factors. METHODS:The authors investigated the follow-u...

journal_title：Cancer

authors： Sano T,Sasako M,Kinoshita T,Maruyama K

更新日期：1993-12-01 00:00:00

abstract：BACKGROUND:The aim of this study was to examine p16(INK4a) protein expression in ThinPrep (Cytyc Corporation, Marlborough, Mass) cervical specimens by using the CINtec p16(INK4a) Cytology Kit (Dako, Glostrup, Denmark). The ability of this assay to accurately identify underlying high-grade lesions was assessed by using ...

journal_title：Cancer

authors： Meyer JL,Hanlon DW,Andersen BT,Rasmussen OF,Bisgaard K

更新日期：2007-04-25 00:00:00

abstract：BACKGROUND:The polyamine system is a promising target for anticancer therapy. Ideally, an antineoplastic compound affecting this system should inhibit both ornithine decarboxylase and the polyamine transporter, and toxicity should be mild. Agmatine, decarboxylated L-arginine, appears to be such a compound. METHODS:Ade...

journal_title：Cancer

authors： Molderings GJ,Kribben B,Heinen A,Schröder D,Brüss M,Göthert M

更新日期：2004-08-15 00:00:00

abstract：:The clinical findings in 262 patients with melanoma were correlated with an assessment of their cellular-mediated immunity by delayed-type hypersensitivity (DTH) skin tests, by lymphocyte blastogenesis, and by leukocyte enumerations. Patients with systemic metastases (stage IV) and those with evidence of tumor burden ...

journal_title：Cancer

authors： Pritchard DJ,Ritts RE Jr,Taylor WF,Miller GC

更新日期：1978-06-01 00:00:00

abstract：:Acquired myeloperoxidase deficiency has been reported in several hematological malignancies. The clinical course of a patient with acute myelomonocytic leukemia is described which was characterized by staphylococcal infections prior to therapy and again during a period of relapse. Neutropenia was not a feature of thes...

journal_title：Cancer

authors： Kitahara M,Kushner JP

更新日期：1979-12-01 00:00:00

abstract：BACKGROUND AND METHODS:Predictors of distant relapse following conservative surgery for breast cancer were studied in a review of 425 women. Five steps of breast cancer patient management were defined in which increasing amounts of information, potentially relevant to prognosis for metastasis-free survival (MFS), were ...

journal_title：Cancer

authors： Tubiana-Hulin M,Le Doussal V,Hacene K,Rouëssé J,Brunet M

更新日期：1993-08-15 00:00:00

abstract：:A retrospective study is reported of 120 consecutive cases of patients presenting with brain metastases as the primary sign of their malignancy. Primary site was found in 62 patients (53 while alive and 9 at postmortem examination) and remained unknown in 58. Lung was the most frequent primary site (45% of known sites...

journal_title：Cancer

authors： Le Chevalier T,Smith FP,Caille P,Constans JP,Rouesse JG

更新日期：1985-08-15 00:00:00

abstract：BACKGROUND:The authors recently reported on the role of cyclin E in differentiating ovarian/primary peritoneal carcinoma from malignant peritoneal mesothelioma using gene expression arrays. In the current study, they analyzed the expression of low-molecular weight (LMW) forms of cyclin E in ovarian carcinoma, malignant...

journal_title：Cancer

authors： Davidson B,Skrede M,Silins I,Shih IeM,Trope CG,Flørenes VA

更新日期：2007-09-15 00:00:00

abstract：:Seventy-three women with metastatic breast cancer were treated with aminoglutethimide and dexamethasone. No complete responses occurred. Ten patients (16%) achieved partial responses (mean duration, 12 months). The proportions of patients responding by disease site were breast (50%), nodes (33%), skin (23%), bone (16%...

journal_title：Cancer

authors： Asbury RF,Bakemeier RF,Fölsch E,McCune CS,Savlov E,Bennett JM

更新日期：1981-04-15 00:00:00

abstract：BACKGROUND:A feasibility study examining the effects of supervised aerobic exercise training on cardiopulmonary and quality of life (QOL) endpoints among postsurgical nonsmall cell lung cancer (NSCLC) patients was conducted. METHODS:Using a single-group design, 20 patients with stage I-IIIB NSCLC performed 3 aerobic c...

journal_title：Cancer

authors： Jones LW,Eves ND,Peterson BL,Garst J,Crawford J,West MJ,Mabe S,Harpole D,Kraus WE,Douglas PS

更新日期：2008-12-15 00:00:00

abstract：:The authors reviewed the liver histopathology and the clinical features of eight patients with liver metastases from colorectal cancer who were treated by hepatic arterial infusion chemotherapy (HAIC) via an implantable pump (Infusaid). Before HAIC, these patients had no evidence of hepatitis, and results of liver bio...

journal_title：Cancer

authors： Doria MI Jr,Shepard KV,Levin B,Riddell RH

更新日期：1986-08-15 00:00:00

abstract：:A study of pneumococcal bacteremia in 56 patients with neoplastic disease from January 1, 1972 to June 30, 1980 is presented and compared to an earlier study between 1955 and 1971. Patients at highest risk were those with Hodgkin's disease who had been splenectomized, multiple myeloma and chronic lymphocytic leukemia ...

journal_title：Cancer

authors： Chou MY,Brown AE,Blevins A,Armstrong D

更新日期：1983-04-15 00:00:00

abstract：:A case of an acute myocardial infarction occurring in a 19-year-old woman, 27 months after mantle radiotherapy for Stage II-A Hodgkin's disease is described. The coronary arteriogram demonstrated patent and normal coronary arteries, but the echocardiogram revealed pericarditis. The clinical course was further complica...

journal_title：Cancer

authors： Yahalom J,Hasin Y,Fuks Z

更新日期：1983-08-15 00:00:00

abstract：:Bladder cancer is one of the malignancies for which considerable information is available regarding molecular pathogenesis and genetic predictors of natural history, as well as response to treatment. Loss of heterozygosity of chromosome 9 appears to be essential to the genesis of superficial bladder cancer, and mutati...

journal_title：Cancer

authors： Raghavan D

更新日期：2003-04-15 00:00:00

abstract：:The National Breast and Cervical Cancer Early Detection Program (NBCCEDP) of the Centers for Disease Control and Prevention (CDC) is implemented through cooperative agreements with state health departments, US territories, and tribal health organizations (grantees). Grantees typically contract with clinicians and othe...

journal_title：Cancer

authors： Yancy B,Royalty JE,Marroulis S,Mattingly C,Benard VB,DeGroff A

更新日期：2014-08-15 00:00:00

abstract：BACKGROUND:Children with average-risk acute lymphoblastic leukemia (AR-ALL) face many challenges that can adversely affect their quality of life (QOL). However, to the authors' knowledge, patterns and predictors of QOL impairment during therapy have not been well characterized to date. METHODS:Patients with AR-ALL who...

journal_title：Cancer

authors： Zheng DJ,Lu X,Schore RJ,Balsamo L,Devidas M,Winick NJ,Raetz EA,Loh ML,Carroll WL,Sung L,Hunger SP,Angiolillo AL,Kadan-Lottick NS

更新日期：2018-02-01 00:00:00

abstract：:The concentrations of sex hormone binding globulin (SHBG) were measured in the plasma of 56 men, who were 47 to 85 years of age, by time-resolved immunofluorometric assay with a monoclonal antibody. Twenty-five of the men had untreated carcinoma of the prostate and 17 had untreated prostatic hyperplasia. There were 14...

journal_title：Cancer

authors： Grasso M,Buonaguidi A,Mondina R,Borsellino G,Lania C,Banfi G,Rigatti P

更新日期：1990-07-15 00:00:00

abstract：BACKGROUND:Two randomized trials have demonstrated improved progression-free survival (PFS) with lenalidomide maintenance after autologous transplantation for multiple myeloma (MM). Overall survival (OS) results are conflicting, and quality-of-life (QOL) data are lacking. The authors conducted a systematic survey of pa...

journal_title：Cancer

authors： Burnette BL,Dispenzieri A,Kumar S,Harris AM,Sloan JA,Tilburt JC,Kyle RA,Rajkumar SV

更新日期：2013-12-15 00:00:00

abstract：:An unusual case of myeloproliferative disorder in which mature and immature myeloid cells were found to contain unusual cytoplasmic inclusions is reported. By light microscopy, these inclusions could be observed with Wright's stain. By electron microscopy they appeared to consist of a pale, finely granular material wi...

journal_title：Cancer

authors： Coppola A,O'Connor J

更新日期：1977-11-01 00:00:00

abstract：BACKGROUND:Uterine leiomyosarcoma (ULMS) is identified in 0.1% to 0.2% of hysterectomy specimens of presumed leiomyoma. To date, there is no preoperative technique that reliably differentiates ULMS from uterine leiomyoma. Increasing use of minimally invasive approaches for the management of leiomyomas may result in ina...

journal_title：Cancer

authors： George S,Barysauskas C,Serrano C,Oduyebo T,Rauh-Hain JA,Del Carmen MG,Demetri GD,Muto MG

更新日期：2014-10-15 00:00:00

abstract：BACKGROUND:To the authors' knowledge there is little information available regarding the effectiveness of standard antiemetic therapy among cancer patients who receive emetogenic chemotherapy in clinical practice, especially in the pediatric population. The current study was undertaken to determine the effectiveness of...

journal_title：Cancer

authors： Holdsworth MT,Raisch DW,Frost J

更新日期：2006-02-15 00:00:00

abstract：:Treatment with BCG (Bacillus Calmette-Guérin) followed by irradiation was attempted to improve response to therapy by cutaneous metastases from malignant skin melanomas. Both agents were applied in low doses, known to cause minimal side effects. Nineteen patients, divided into three groups, entered the clinical trial....

journal_title：Cancer

authors： Plesnicar S,Rudolf Z

更新日期：1982-09-15 00:00:00

abstract：:BALB/c mice were hyperimmunized with ACHN (ATCC CRL 1611, American Type Culture Collection, Rockville, Maryland), a stable in vitro cell line derived from a malignant pleural effusion in a 22-year-old man with renal cell carcinoma. The hyperimmune spleen cells were fused with NS-1 murine myeloma cells using polyethyle...

journal_title：Cancer

authors： Kochevar J

更新日期：1987-06-15 00:00:00

abstract：BACKGROUND:Cancer costs should be discussed by patients and providers, but information is not readily available. Results from recently published studies (in the last 5 years) on direct and indirect cancer costs may help guide these discussions. METHODS:The authors reviewed studies published between 2013 and 2017 that ...

journal_title：Cancer

authors： Pisu M,Henrikson NB,Banegas MP,Yabroff KR

更新日期：2018-11-01 00:00:00

abstract：BACKGROUND:The authors conducted this study to update their experience with patients who have ovarian serous borderline tumors with noninvasive peritoneal implants, with the objectives of gaining additional insight into the biologic behavior of these tumors and understanding better the effects of postoperative treatmen...

journal_title：Cancer

authors： Gershenson DM,Silva EG,Tortolero-Luna G,Levenback C,Morris M,Tornos C

更新日期：1998-11-15 00:00:00

abstract：BACKGROUND:Novel approaches to increasing the therapeutic efficacy of targeted radiotherapy of cancer are required. One strategy to achieve this goal is to induce high-level expression of a receptor on the surface of tumor cells that can be targeted with a radiolabeled peptide. The objectives of this study were to 1) i...

journal_title：Cancer

authors： Rogers BE,Zinn KR,Lin CY,Chaudhuri TR,Buchsbaum DJ

更新日期：2002-02-15 00:00:00

abstract：:External-beam irradiation of prostatic cancer was introduced at Stanford in 1956. The program has sought to determine the following: whether prostatic carcinoma can be cured by external beam radiation therapy, with what frequency this can be accomplished, which patients are best suited for irradiation, and what techni...

journal_title：Cancer

authors： Bagshaw MA,Ray GR,Cox RS

更新日期：1987-08-01 00:00:00

abstract：BACKGROUND:Colonoscopic screening has increased detection of malignant colonic polyps (MPs). The goal of this study was to analyze trends and patterns in the surgical treatment of MPs and to assess outcomes as measured by lymph node retrieval and patient survival. METHODS:The Surveillance, Epidemiology, and End Result...

journal_title：Cancer

authors： Wasif N,Etzioni D,Maggard MA,Tomlinson JS,Ko CY

更新日期：2011-03-01 00:00:00

abstract：:Serum immunoglobulin levels IgA, IgG, and IgM have been estimated in 92 patients with breast cancer and 50 control patients, 40 of whom had benign disease of the breast. In patients with breast cancer, IgA was significantly raised at all stages and IgG was significantly reduced, but the two abnormalities were not nece...

journal_title：Cancer

authors： Roberts MM,Bathgate EM,Stevenson A

更新日期：1975-07-01 00:00:00

abstract：BACKGROUND:Patients affected by neurofibromatosis type 1 (NF1) are at higher risk of developing soft-tissue sarcomas (STS) than the general population. The clinical findings and outcome in 43 children and adolescents with NF1 treated for STS in the Italian protocols between 1988 and 2004 are reported. METHODS:The stud...

journal_title：Cancer

authors： Ferrari A,Bisogno G,Macaluso A,Casanova M,D'Angelo P,Pierani P,Zanetti I,Alaggio R,Cecchetto G,Carli M

更新日期：2007-04-01 00:00:00