Treatment of metastatic breast cancer with aminoglutethimide.

abstract：:The physician must suspect pancreatic cancer in patients older than age 40 years who present with minimal vague symptoms. The presence of common disorders such as gallstones, hiatal hernia and diverticulosis coli, does not exclude pancreatic cancer. Ultrasonography, computed tomography, ERCP and cytology are the essen...

journal_title：Cancer

authors： Moossa AR

更新日期：1982-12-01 00:00:00

abstract：:Thyroglobulin messenger RNA (mRNA) was located and quantified in tissue sections of differentiated human thyroid cancers by in situ hybridization using cloned complementary DNA probes. The cells of the well-differentiated follicular and papillary forms contained similar levels of thyroglobulin mRNA, corresponding to a...

journal_title：Cancer

authors： Bergé-Lefranc JL,Cartouzou G,De Micco C,Fragu P,Lissitzky S

更新日期：1985-07-15 00:00:00

abstract：:This study concerns 75 patients with squamous cell carcinoma of the oral cavity who were patients at the Gustave-Roussy Institute between December 1966 and July 1973. These patients were divided into two groups. The first group was comprised of 39 patients who underwent elective radical neck dissection; nodal involvem...

journal_title：Cancer

authors： Vandenbrouck C,Sancho-Garnier H,Chassagne D,Saravane D,Cachin Y,Micheau C

更新日期：1980-07-15 00:00:00

abstract：:A Phase I/II accelerated fractionation study for high-grade cerebral astrocytomas began in October 1987. Forty-two patients, 25 men and 17 women, were entered in the study. Median age was 58.5 years of age (range, 32 to 78 years). Performance status was 0, 1, 2, and 3 on Eastern Cooperative Oncology Group (ECOG) scale...

journal_title：Cancer

authors： Shenouda G,Souhami L,Freeman CR,Hazel J,Lehnert S,Joseph L

更新日期：1991-05-01 00:00:00

abstract：:A 69-year-old man with metastatic islet cell carcinoma was treated with streptozotocin and achieved excellent tumor regression. Sixty-seven grams of streptozotocin were given over 28 months. After completion of streptozotocin therapy, the patient had progressive leukopenia. Thirteen months after discontinuation of str...

journal_title：Cancer

authors： Green MR,Anderson RE

更新日期：1981-04-15 00:00:00

abstract：:The clinical, patient-oriented focus of medicine and psychology is contrasted with the epidemiologic (public health) approach in assessing the role of life-style factors and health promotion in cancer research. The unifying host-agent-environment epidemiologic paradigm is applied to contemporary cancer prevention issu...

journal_title：Cancer

authors： Celentano DD

更新日期：1991-02-01 00:00:00

abstract：BACKGROUND:This report evaluated whether biochemical recurrence (BCR) as a time-dependent covariate (t) after radical prostatectomy (RP) for prostate cancer was associated with the risk of death and whether salvage therapy with radiotherapy (RT) and/or hormonal therapy (HT) can lessen this risk METHODS:This was a retr...

journal_title：Cancer

authors： Choueiri TK,Chen MH,D'Amico AV,Sun L,Nguyen PL,Hayes JH,Robertson CN,Walther PJ,Polascik TJ,Albala DM,Moul JW

更新日期：2010-04-15 00:00:00

abstract：BACKGROUND:Factors contributing to the lower likelihood of urologist follow-up among African American (AA) men diagnosed with prostate cancer may not be strictly related to patient factors. The authors investigated the relationship between crime, poverty, and poor housing, among others, and postdiagnosis urologist visi...

journal_title：Cancer

authors： Onukwugha E,Osteen P,Jayasekera J,Mullins CD,Mair CA,Hussain A

更新日期：2014-11-01 00:00:00

abstract：:Autopsy slides from 22 melanoma patients who received bacille Calmette-Guérin BCG immunotherapy and who had a postmortem examination at the UCLA Center for the Health Sciences were examined for the presence of granulomas. Granulomas were found in six patients (29%) who received BCG but not in a group of 25 melanoma pa...

journal_title：Cancer

authors： Hatzitheofilou C,Obenchain DF,Porter DD,Morton DL

更新日期：1982-01-01 00:00:00

abstract：BACKGROUND:The objective of the current study was to examine the impact of adherence to guidelines on stage-specific survival outcomes in patients with stage III and high-risk stage II colon cancer. The National Comprehensive Cancer Network (NCCN) has established working, expert consensus, and evidence-based guidelines...

journal_title：Cancer

authors： Boland GM,Chang GJ,Haynes AB,Chiang YJ,Chagpar R,Xing Y,Hu CY,Feig BW,You YN,Cormier JN

更新日期：2013-04-15 00:00:00

abstract：BACKGROUND:Tamoxifen has been used in the treatment of patients with metastatic malignant melanoma either as a single agent or, more commonly, in combination with other chemotherapeutic agents. The aim of the current study was to summarize the available clinical evidence on the role of the tamoxifen in different combin...

journal_title：Cancer

authors： Lens MB,Reiman T,Husain AF

更新日期：2003-10-01 00:00:00

abstract：:The presence of hepatitis B virus (HBV) has been evaluated in liver specimens from 11 children with primary liver tumors and negative results of serologic testing for HBV markers. HBV-DNA sequences were detected by the polymerase chain reaction procedure, using different sets of oligonucleotide primers from highly con...

journal_title：Cancer

authors： Pontisso P,Morsica G,Ruvoletto MG,Barzon M,Perilongo G,Basso G,Cecchetto G,Chemello L,Alberti A

更新日期：1992-06-01 00:00:00

abstract：BACKGROUND:Male urethral cancer is a rare neoplasm, with the published literature consisting of small single-institution retrospective series. As such, there is no objective analysis of prognostic factors and treatment outcome. The author sought to use the population-based Surveillance, Epidemiology, and End Results (S...

journal_title：Cancer

authors： Rabbani F

更新日期：2011-06-01 00:00:00

abstract：BACKGROUND:Increased pretreatment serum interleukin (IL)-6 levels among patients with head and neck squamous cell carcinoma (HNSCC) have been shown to correlate with poor prognosis, but sample sizes in prior studies have been small and thus unable to control for other known prognostic variables. METHODS:A longitudinal...

journal_title：Cancer

authors： Duffy SA,Taylor JM,Terrell JE,Islam M,Li Y,Fowler KE,Wolf GT,Teknos TN

更新日期：2008-08-15 00:00:00

abstract：:The treatment for women diagnosed with early breast cancer is complex, dynamic, and controversial. More choices are available for local control and indications for systemic adjuvant therapy have changed dramatically. Knowledge of predictable physical and psychological responses through the various phases of primary tr...

journal_title：Cancer

authors： Knobf MT

更新日期：1990-09-15 00:00:00

abstract：:Mixed cellularity Hodgkin's disease and diffuse non-Hodgkin's lymphoma, mixed cell type, occurred consecutively in a husband and wife. Both patients demonstrated monoclonal IgM gammopathies. The unusual nature and possible significance of these findings are discussed. ...

journal_title：Cancer

authors： Offit K,Macris NT,Hellman G,Rotterdam HZ

更新日期：1986-01-15 00:00:00

abstract：:In the evaluation of cervical cancer, computed tomography (CT) is used primarily to stage advanced tumors and evaluate for recurrence. Because of reports that CT imaging lacks sensitivity and specificity in the detection of primary tumors and metastatic lesions, its use in these applications has been limited, but rece...

journal_title：Cancer

authors： Pannu HK,Fishman EK

更新日期：2003-11-01 00:00:00

abstract：:A series of eight plasma cell granulomas of the lung were examined. Their clinical, pathologic, and immunohistochemical characteristics as well as the ultrastructural features of one case are in agreement with those found in the literature. One patient died after a surgical intervention complicated by invasion of pulm...

journal_title：Cancer

authors： Warter A,Satge D,Roeslin N

更新日期：1987-02-01 00:00:00

abstract：BACKGROUND:The purpose of the current study was to determine the frequency of 'probably benign' interpretations at breast magnetic resonance (MR) imaging screening of high-risk women and the frequency of subsequent malignancy in these women. METHODS:The authors performed a retrospective review of the records of 367 as...

journal_title：Cancer

authors： Liberman L,Morris EA,Benton CL,Abramson AF,Dershaw DD

更新日期：2003-07-15 00:00:00

abstract：:Transforming growth factors (TGF) are polypeptides that stimulate anchorage-independent growth of various nontransformed cells in vitro. Transforming growth factors have been found in tumor extracts and in the urine of cancer patients. The specific questions of our study were whether TGF activity can be detected in ma...

journal_title：Cancer

authors： Hanauske AR,Arteaga CL,Clark GM,Buchok J,Marshall M,Hazarika P,Pardue RL,Von Hoff DD

更新日期：1988-05-01 00:00:00

abstract：:The antitumor effect of human leukocyte interferon was investigated on ten patients with malignant brain tumor. In eight cases of primary tumor, IFN alone was administered when their recurrent sign was evident. A dose of 3 X 10(6) IU or 1 X 10(6) IU of IFN was injected intramuscularly two or three times a week in high...

journal_title：Cancer

authors： Hirakawa K,Ueda S,Nakagawa Y,Suzuki K,Fukuma S,Kita M,Imanishi J,Kishida T

更新日期：1983-06-01 00:00:00

abstract：BACKGROUND:Colonoscopy is the most widely used colorectal cancer (CRC) screening test in the United States. Through the detection and removal of potentially precancerous polyps, it can prevent CRC. However, CRC screening remains low among adults who are recommended for screening. The New Hampshire Colorectal Cancer Scr...

journal_title：Cancer

authors： Rice K,Sharma K,Li C,Butterly L,Gersten J,DeGroff A

更新日期：2019-02-15 00:00:00

abstract：:Selective adsorption of several common "monospecific" HLA typing sera with HLA typed platelets, purified B lymphocytes, cultured lymphoid cells, or lymphocytes from patients with active chronic lymphocytic leukemia demonstrated that many of these sera contain antibodies to non-HLA antigens. Antibodies were detected to...

journal_title：Cancer

authors： Pollack MS,DuBois D

更新日期：1977-06-01 00:00:00

abstract：:Cardiac metastases from malignant melanoma are frequent, usually asymptomatic and occur terminally. When responsible for symptoms, close evaluation of the patient is imperative for correct diagnosis and subsequent therapy. Surgical intervention where indicated in combination with chemotherapy and judicious use of irra...

journal_title：Cancer

authors： Thomas JH,Panoussopoulos DG,Jewell WR,Pierce GE

更新日期：1977-04-01 00:00:00

abstract：:Arylsulfatase B activity has been determined in 24-hour urine samples from 243 patients with colorectal cancer. Elevated activity of the enzyme was obsereved in 172 out of 243 (71%) patients. Employing Dukes' modified classification of colorectal cancer, urine arylsulfatase B activity was elevated in Dukes' A lesions-...

journal_title：Cancer

authors： Morgan LR Jr,Samuels MS,Thomas W,Krementz ET,Meeker W

更新日期：1975-12-01 00:00:00

abstract：:A prospective study was performed on 84 patients with neuroendocrine pancreatic tumors. Fifty-nine (70%) had malignant tumors and received causal medical treatment. Streptozotocin in combination with 5-fluorouracil or doxorubicin was used as first-line treatment and produced overall objective responses in 20 of 44 (45...

journal_title：Cancer

authors： Eriksson B,Skogseid B,Lundqvist G,Wide L,Wilander E,Oberg K

更新日期：1990-05-01 00:00:00

abstract：BACKGROUND:This study was conducted to evaluate the long-term outcomes in patients with stage IE and IIE mucosa-associated lymphoid tissue (MALT) lymphomas treated with involved field radiotherapy (RT). METHODS:Between 1989 and 2004, 192 patients with stage I and II MALT lymphomas were treated. The report focuses on 1...

journal_title：Cancer

authors： Goda JS,Gospodarowicz M,Pintilie M,Wells W,Hodgson DC,Sun A,Crump M,Tsang RW

更新日期：2010-08-15 00:00:00

abstract：:Previous studies have indicated that OK-432 is a potent biologic response modifier (BRM) and that it augments immune responses to tumor cells. We studied the direct effect of OK-432 on tumor cells. Established and freshly derived human ovarian carcinoma lines were examined for their susceptibility to OK-432 or its sub...

journal_title：Cancer

authors： Nio Y,Zighelboim J,Berek J,Bonavida B

更新日期：1989-07-15 00:00:00

abstract：BACKGROUND:Few previous articles have analyzed the relation between infection with Helicobacter pylori (H. pylori) and primary gastric lymphoma in a large number of patients. METHODS:Resected and biopsied specimens from 237 patients with primary gastric lymphoma were investigated for H. pylori using hematoxylin and eo...

journal_title：Cancer

authors： Nakamura S,Yao T,Aoyagi K,Iida M,Fujishima M,Tsuneyoshi M

更新日期：1997-01-01 00:00:00

abstract：BACKGROUND:Angiogenesis in individuals with various solid tumors has provided useful information on tumor progression and prognosis, and many examples of mast cell (MC) accumulation coupled with angiogenesis can be found in the literature. METHODS:Utilizing monoclonal antibodies for tryptase that are specific markers ...

journal_title：Cancer

authors： Takanami I,Takeuchi K,Naruke M

更新日期：2000-06-15 00:00:00