Acute myelocytic leukemia following prolonged streptozotocin therapy.

abstract：BACKGROUND:Infection is a significant cause of death in patients with aplastic anemia (AA). However, few recent studies have examined infectious complications in patients with AA. METHODS:The authors retrospectively evaluated the type of infections, associated pathogens, and outcome of infectious episodes (IEs) in pat...

journal_title：Cancer

authors： Torres HA,Bodey GP,Rolston KV,Kantarjian HM,Raad II,Kontoyiannis DP

更新日期：2003-07-01 00:00:00

abstract：BACKGROUND:Novel approaches to increasing the therapeutic efficacy of targeted radiotherapy of cancer are required. One strategy to achieve this goal is to induce high-level expression of a receptor on the surface of tumor cells that can be targeted with a radiolabeled peptide. The objectives of this study were to 1) i...

journal_title：Cancer

authors： Rogers BE,Zinn KR,Lin CY,Chaudhuri TR,Buchsbaum DJ

更新日期：2002-02-15 00:00:00

abstract：BACKGROUND:A 59-year-old male developed intractable hiccups during monthly therapy with high dose dexamethasone for multiple myeloma. Hiccups would begin hours after his first dose and continue over the 4 days of therapy. He sought assistance after his attempt at home remedies failed and the hiccups became exhausting. ...

journal_title：Cancer

authors： Cersosimo RJ,Brophy MT

更新日期：1998-01-15 00:00:00

abstract：BACKGROUND:Surgery alone is the appropriate first-line treatment for patients with mesoblastic nephroma (MN). Nevertheless, there are reports of local recurrences and metastasis, especially in the cellular subtype. The authors evaluated the outcome of patients with MN who were enrolled in either the International Socie...

journal_title：Cancer

authors： Furtwaengler R,Reinhard H,Leuschner I,Schenk JP,Goebel U,Claviez A,Kulozik A,Zoubek A,von Schweinitz D,Graf N,Gesellschaft fur Pädiatrische Onkologie und Hämatologie (GPOH) Nephroblastoma Study Group.

更新日期：2006-05-15 00:00:00

abstract：BACKGROUND:Over the past 2 decades, significant progress has been made in the field of metastatic colorectal cancer (mCRC) regarding new imaging techniques, surgical interventions, and systemic therapy. It is not known whether the benefit from these interventions has extended overall survival (OS) within the general mC...

journal_title：Cancer

authors： Golan T,Urban D,Berger R,Lawrence YR

更新日期：2013-08-15 00:00:00

abstract：BACKGROUND:Because angiogenesis may play a role in the pathogenesis of acute myeloid leukemia (AML) and high-risk myelodysplastic syndrome (MDS), and thalidomide (Th) has shown significant anti-angiogenic activity, this study was designed to investigate the potential role of Th in the treatment of patients with AML and...

journal_title：Cancer

authors： Cortes J,Kantarjian H,Albitar M,Thomas D,Faderl S,Koller C,Garcia-Manero G,Giles F,Andreeff M,O'Brien S,Keating M,Estey E

更新日期：2003-03-01 00:00:00

abstract：:Fibronectin, a high molecular weight glycoprotein component of the extracellular matrix, was localized extracellularly and intracellularly in the nuclei and the cytoplasm of hepatocellular carcinomas (HCC) by the use of the biotin-avidin method on paraffin-embedded, pepsin-treated tissue. The specificity of the staini...

journal_title：Cancer

authors： Jagirdar J,Ishak KG,Colombo M,Brambilla C,Paronetto F

更新日期：1985-10-01 00:00:00

abstract：BACKGROUND:Crizotinib is a tyrosine kinase inhibitor active against ALK, MET, and ROS1. We previously reported that crizotinib decreases testosterone in male patients. The detailed etiology of the effect, its symptomatic significance, and the effectiveness of subsequent testosterone replacement have not been previously...

journal_title：Cancer

authors： Weickhardt AJ,Doebele RC,Purcell WT,Bunn PA,Oton AB,Rothman MS,Wierman ME,Mok T,Popat S,Bauman J,Nieva J,Novello S,Ou SH,Camidge DR

更新日期：2013-07-01 00:00:00

abstract：:Ovarian, fallopian tube, and peritoneal cancers have a similar clinical presentation and are treated similarly, and current evidence supports staging all 3 cancers in a single system. The primary site (i.e. ovary, fallopian tube, or peritoneum) should be designated where possible. The histologic type should be recorde...

journal_title：Cancer

authors： Prat J,FIGO Committee on Gynecologic Oncology.

更新日期：2015-10-01 00:00:00

abstract：:Estrogen receptors in breast tumors were assayed in 55 premenopausal women undergoing bilateral oophorectomy and in 120 postmenopausal women undergoing bilateral adrenalectomy for treatment of metastatic breast cancer. The data show that 20 (60%) of the 32 patients with estrogen receptor-positive (ER+) tumors had obje...

journal_title：Cancer

authors： Dao TL,Nemoto T

更新日期：1980-12-15 00:00:00

abstract：:Two consecutive trials for the treatment of childhood non-Hodgkin's lymphoma were evaluated, carried out by the same cooperative groups. Group A: From June, 1973 to December, 1975, 50 evaluable patients under 16 years of age participated in a study that included vincristine and prednisone plus surgery and/or radiother...

journal_title：Cancer

authors： Sackmann-Muriel F,Diez B,Schvartzman E,Braier JL,Schwartz L,Gallo G,Pavlovsky S

更新日期：1984-12-15 00:00:00

abstract：:A summary is presented of those organ specific enzyme assays traditionally used in evaluation of the patient with cancer. In addition, the use of certain serum enzymes such as gamma-glutamyl transpeptidase, phosphohexose isomerase or 5'-nucleotidase as aids in following the course of the disease, particularly in patie...

journal_title：Cancer

authors： Schwartz MK

更新日期：1976-01-01 00:00:00

abstract：BACKGROUND:Receipt of chemotherapy at the end of life (EOL) is considered an indicator of poor quality of care for medical oncology. The objective of this study was to characterize the use of radiotherapy (RT) in patients with nonsmall cell lung cancer (NSCLC) during the same period. METHODS:Treatment characteristics ...

journal_title：Cancer

authors： Kapadia NS,Mamet R,Zornosa C,Niland JC,D'Amico TA,Hayman JA

更新日期：2012-09-01 00:00:00

abstract：:A high percentage of children with Wilms' tumor are cured with multimodal treatment. A small percentage of these children will develop second tumors, perhaps related to a genetic predisposition to neoplasia or possibly secondary to the treatment utilized for Wilms' tumor. Malignant mesothelioma has been associated wit...

journal_title：Cancer

authors： Antman KH,Ruxer RL Jr,Aisner J,Vawter G

更新日期：1984-07-15 00:00:00

abstract：:Ninety-five patients with non-oat cell lung cancer underwent resection of all apparent disease and were followed for a minimum of 36 months. Incidence of recurrence was 34% in 47 patients with N0 disease, 65% in 32 patients with N1 disease, and 81.3% in 16 patients with N2 disease (P less than 0.02 and P less than 0.0...

journal_title：Cancer

authors： Iascone C,DeMeester TR,Albertucci M,Little AG,Golomb HM

更新日期：1986-02-01 00:00:00

abstract：:The purpose of this study was to characterize the clinical features of laboratory-confirmed influenza in 20 children and young adults with cancer who were receiving immunosuppressive therapy. Viruses isolated from pharyngeal and nasopharyngeal cultures were identified as the A/Hong Kong/1/68 strain or one of its varia...

journal_title：Cancer

authors： Feldman S,Webster RG,Sugg M

更新日期：1977-01-01 00:00:00

abstract：BACKGROUND:Treatment of febrile neutropenia (FN) is costly, because it typically involves hospitalization. As cancer rates continue to increase, the number of patients suffering from FN will also increase, making it important to quantify the costs of treating this condition accurately and comprehensively. METHODS:A co...

journal_title：Cancer

authors： Lathia N,Mittmann N,DeAngelis C,Knowles S,Cheung M,Piliotis E,Shear N,Walker S

更新日期：2010-02-01 00:00:00

abstract：:Four cases of an ulcero-proliferative lesion of putative histiocytic origin, arising in the oral cavity, are described. This lesion, which has not been defined previously, is easily confused histologically with a malignant process of lymphoid origin, thereby representing a pseudolymphomatous proliferation. Light micro...

journal_title：Cancer

authors： Eversole LR,Leider AS,Jacobsen PL,Kidd PM

更新日期：1985-04-15 00:00:00

abstract：BACKGROUND:Bortezomib has preclinical and clinical in B-cell lymphomas, both alone and in combination with other agents. A phase 1 evaluation was conducted of bortezomib with rituximab plus cyclophosphamide, doxorubicin, vincristine, and prednisone (R-CHOP) in patients with untreated diffuse large B-cell lymphoma (DLBC...

journal_title：Cancer

authors： Furman RR,Martin P,Ruan J,Cheung YK,Vose JM,LaCasce AS,Elstrom R,Coleman M,Leonard JP

更新日期：2010-12-01 00:00:00

abstract：:The best practice of Sacramento's Asian American Network for Cancer Awareness Research and Training program is friendships and relationships. ...

journal_title：Cancer

authors： Shimizu R,Chen MS Jr,Snipes KP,Chan A,Wilson GR,Chong JL,Bal DG

更新日期：2005-12-15 00:00:00

abstract：BACKGROUND:The spontaneous formation of neutralizing antibodies (inhibitors) to factor VIII (FVIII) in patients with cancer is a well known phenomenon. However, to the authors' knowledge there is lack of information in the literature with respect to the clinical course of these patients and the nature of the associatio...

journal_title：Cancer

authors： Sallah S,Wan JY

更新日期：2001-03-15 00:00:00

abstract：:Ewing's sarcoma is a small cell malignant tumor that usually arises in the medullary cavity of bone. Less frequently, it originates in soft tissue and may secondarily invade underlying bone. The origin of Ewing's sarcoma in a periosteal location without extension into either the bone or adjacent soft tissue has not be...

journal_title：Cancer

authors： Bator SM,Bauer TW,Marks KE,Norris DG

更新日期：1986-10-15 00:00:00

abstract：BACKGROUND:Several studies have shown that lysophosphatidic acid (LPA), a phospholipidic chemical mediator, is relevant to the pathogenesis of ovarian carcinoma. Higher plasma levels of LPA have been reported in patients with ovarian carcinoma than in healthy patients, and LPA is known to activate ovarian carcinoma cel...

journal_title：Cancer

authors： Tokumura A,Tominaga K,Yasuda K,Kanzaki H,Kogure K,Fukuzawa K

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND:Response rates to second-line chemotherapy in recurrent high-grade glial tumors are low and new effective treatments are needed. The objective of this study was to evaluate response rates and tolerability of chemotherapy with bevacizumab and irinotecan in recurrent high-grade gliomas. METHODS:Twenty patient...

journal_title：Cancer

authors： Bokstein F,Shpigel S,Blumenthal DT

更新日期：2008-05-15 00:00:00

abstract：BACKGROUND:Initial clinic studies revealed that the overexpression of proline-directed protein kinase F(A) (PDPK F(A)) is associated conversely with various stages of tumor tissue differentiation. However, the role of overexpressed PDPK F(A) in tumor cell differentiation remains unknown and needs to be established. In ...

journal_title：Cancer

authors： Hsu CP,Yang CC,Yang SD

更新日期：2000-09-01 00:00:00

abstract：:Between August 1978 and November 1981, 33 boys with acute lymphocytic leukemia (ALL) (26 non-T, 7 T-cell) younger than 16 years underwent bilateral wedge testicular biopsies at the time of initial diagnosis. Seven (4 non-T, 3 T-cell) demonstrated focal leukemic infiltrates. Rebiopsy after successful induction therapy ...

journal_title：Cancer

authors： Kim TH,Hargreaves HK,Chan WC,Brynes RK,Alvarado C,Woodard J,Ragab AH

更新日期：1986-03-01 00:00:00

abstract：BACKGROUND:Screening over many years is required to optimize reductions in colorectal cancer (CRC) mortality. However, no prior trials have compared strategies for obtaining long-term adherence. METHODS:Systems of Support to Increase Colorectal Cancer Screening and Follow-Up was implemented in an integrated health car...

journal_title：Cancer

authors： Green BB,Anderson ML,Cook AJ,Chubak J,Fuller S,Meenan RT,Vernon SW

更新日期：2017-11-15 00:00:00

abstract：:The nitroblue tetrazolium test (NBT) was evaluated in 111 patients with cancer. Patients were placed into control and "presumed infected" groups. The mean NBT score for the control group, 6.3, was significantly greater than the mean for a group of normal volunteers, 3.1, but the mean score for the "presumed infected" ...

journal_title：Cancer

authors： Lehane DE,Watson S,Lane M

更新日期：1975-05-01 00:00:00

abstract：:Exposure of tumor cells to reduced folates before or with the fluoropyrimidines, 5-fluorouracil or 5-fluoro-2'deoxyuridine, results in a substantial increase in the activity of these drugs. Available evidence suggests that the mechanism of this synergism is a kinetic stabilization of complex formed between thymidylate...

journal_title：Cancer

authors： Morgan RG

更新日期：1989-03-15 00:00:00

abstract：:One-hundred and fifty-one adults with acute non-lymphocytic leukemia (ANLL) were entered into an Eastern Cooperative Oncology Group protocol (EST-1473) comparing twice daily cytosine arabinoside and thioguanine (AT) with weekly cyclophosphamide, cytosine arabinoside, and methotrexate (CAM) for remission induction. Of ...

journal_title：Cancer

authors： Skeel RT,Costello W,Bennett JM,Oken MM,Tobin MS,Bertino JR,Marsh JC,Carbone PP

更新日期：1980-01-15 00:00:00