Symptomatic reduction in free testosterone levels secondary to crizotinib use in male cancer patients.

abstract：BACKGROUND:Esophageal carcinoma is a major cause of cancer-related deaths among males in Taiwan. However, to date, the genetic alterations that accompany this lethal disease are not understood. METHODS:Chromosomal aberrations of 46 samples of esophageal squamous cell carcinoma (EC-SCC) were analyzed by comparative gen...

journal_title：Cancer

authors： Yen CC,Chen YJ,Chen JT,Hsia JY,Chen PM,Liu JH,Fan FS,Chiou TJ,Wang WS,Lin CH

更新日期：2001-12-01 00:00:00

abstract：:The physician must suspect pancreatic cancer in patients older than age 40 years who present with minimal vague symptoms. The presence of common disorders such as gallstones, hiatal hernia and diverticulosis coli, does not exclude pancreatic cancer. Ultrasonography, computed tomography, ERCP and cytology are the essen...

journal_title：Cancer

authors： Moossa AR

更新日期：1982-12-01 00:00:00

abstract：:A squamous cell carcinoma arising in intralobar bronchopulmonary sequestration of the right lower lobe is described in a 69-year-old man. One other reported case was found. Other complications of bronchopulmonary sequestration include nonspecific infections and tuberculosis. ...

journal_title：Cancer

authors： Bell-Thomson J,Missier P,Sommers SC

更新日期：1979-07-01 00:00:00

abstract：:Categories of objective response to chemotherapy for 460 advanced relapsing prostate cancer patients evaluated in the initial first four randomized clinical trials of the National Prostatic Cancer Project were compared by survival and other patient and disease characteristics. The response criteria for stable were sho...

journal_title：Cancer

authors： Slack NH,Mittelman A,Brady MF,Murphy GP

更新日期：1980-12-01 00:00:00

abstract：BACKGROUND:A phase II prospective trial was carried out to study the concept of 5-fluorouracil (5-FU) dose-intensity in patients with advanced colorectal cancer. Forty patients were treated with 5-FU plus leucovorin (LV), with individually increasing doses of 5-FU. A 5-FU pharmacokinetic follow up was performed and a r...

journal_title：Cancer

authors： Gamelin EC,Danquechin-Dorval EM,Dumesnil YF,Maillart PJ,Goudier MJ,Burtin PC,Delva RG,Lortholary AH,Gesta PH,Larra FG

更新日期：1996-02-01 00:00:00

abstract：BACKGROUND:Initial clinic studies revealed that the overexpression of proline-directed protein kinase F(A) (PDPK F(A)) is associated conversely with various stages of tumor tissue differentiation. However, the role of overexpressed PDPK F(A) in tumor cell differentiation remains unknown and needs to be established. In ...

journal_title：Cancer

authors： Hsu CP,Yang CC,Yang SD

更新日期：2000-09-01 00:00:00

abstract：BACKGROUND:The expression of vascular endothelial growth factor (VEGF)-A isoforms (121, 165, 189, 206), VEGF-B, VEGF-C and VEGF-D in both experimental and clinical models of head and neck squamous cell carcinoma (HNSCC) was determined and correlated with conventional clinicopathologic parameters, with particular refere...

journal_title：Cancer

authors： O-charoenrat P,Rhys-Evans P,Eccles SA

更新日期：2001-08-01 00:00:00

abstract：:Survivors of pediatric and young adult cancers remain at risk for subsequent diseases, including those related to human papillomavirus (HPV) infection. Prevention of HPV acquisition through vaccination has become possible over the last decade. HPV vaccines have been shown to be safe and effective, yet rates of vaccina...

journal_title：Cancer

authors： Temkin SM,Seibel NL

更新日期：2015-10-01 00:00:00

abstract：BACKGROUND:Previous biochemotherapy regimens for metastatic melanoma have required attenuated dosages of interleukin 2 (IL-2) that may have compromised efficacy. METHODS:In a phase 2 study, the authors tested sequential temozolomide (75 mg/m2 per day orally for 3 weeks) followed by high-dose, IL-2 (600,000 U/kg per do...

journal_title：Cancer

authors： Tarhini AA,Kirkwood JM,Gooding WE,Moschos S,Agarwala SS

更新日期：2008-10-01 00:00:00

abstract：BACKGROUND:Although < 1% of men present with prostate-specific antigen (PSA)-negative prostate carcinoma, in that they have serum PSA levels much lower than the tumor burden would suggest, such patients represent a management dilemma. To the authors' knowledge, little information exists in the literature regarding patt...

journal_title：Cancer

authors： Birtle AJ,Freeman A,Masters JR,Payne HA,Harland SJ,BAUS Section of Oncology Cancer Registry.

更新日期：2003-12-01 00:00:00

abstract：BACKGROUND AND METHODS:The antiemetic activity of ondansetron (Zofran, Glaxo Pharmaceuticals, Research Triangle Park, NC) was evaluated in 25 patients with recurrent melanoma who were treated sequentially with dacarbazine (DTIC), vinblastine, and cisplatin. The antiemetic regimen included ondansetron alone in 11 patien...

journal_title：Cancer

authors： Legha SS,Hodges C,Ring S

更新日期：1992-10-01 00:00:00

abstract：:One promising area of current research in chemoprevention is the possibility that micronutrients, including vitamin A analogues, may decrease cancer incidence. The term "vitamin A" refers either to retinol (preformed vitamin A) and its synthetic analogues, or to certain carotenoids (provitamin A), which are converted ...

journal_title：Cancer

authors： Hennekens CH,Mayrent SL,Willett W

更新日期：1986-10-15 00:00:00

abstract：BACKGROUND:The objective of this study was to assess the rate and possible reasons for false-negative (FN) reflex human papillomavirus (HPV)-DNA tests. METHODS:The authors reviewed all ThinPrep cervical specimens that were submitted for reflex HPV-DNA testing using the Digene Hybrid Capture II (HC2) method from Januar...

journal_title：Cancer

authors： Eltoum IA,Chhieng DC,Crowe DR,Roberson J,Jin G,Broker TR

更新日期：2007-06-25 00:00:00

abstract：BACKGROUND:: Delirium has been the most frequent neuropsychiatric complication in patients with advanced cancer. This exploratory study aimed to determine the proportion of patients who were able to recall their experience of delirium and the level of distress experienced by patients, family caregivers, and healthcare ...

journal_title：Cancer

authors： Bruera E,Bush SH,Willey J,Paraskevopoulos T,Li Z,Palmer JL,Cohen MZ,Sivesind D,Elsayem A

更新日期：2009-05-01 00:00:00

abstract：:In 175 premenopausal breast cancer patients, a history of oral contraceptive (OC) use before 20 years of age was significantly associated with higher tumor cell proliferative activity, as indicated by a higher S-phase fraction (SPF), and a higher fraction of DNA aneuploid tumors, compared with later or never users (P ...

journal_title：Cancer

authors： Olsson H,Ranstam J,Baldetorp B,Ewers SB,Fernö M,Killander D,Sigurdsson H

更新日期：1991-03-01 00:00:00

abstract：:Poor drug compliance may cause a decreased survival of children with malignancies. Children who fail to take their medications are not receiving optimum amounts of chemotherapy and suboptimal therapy causes a shortened survival in children with cancer. This is a study of prednisone compliance in 52 children with cance...

journal_title：Cancer

authors： Smith SD,Rosen D,Trueworthy RC,Lowman JT

更新日期：1979-01-01 00:00:00

abstract：:To assess the efficacy of performing both computed tomography (CT) of the thorax and upper abdomen and whole-body gallium scintigraphy for staging lung cancer, the results of each test were compared with those obtained by chest radiography and clinical examination in 100 patients. Clinical efficacy was defined in term...

journal_title：Cancer

authors： MacMahon H,Scott W,Ryan JW,Montner SM,Little AG,Hoffman PC,Ferguson MK,Golomb HM

更新日期：1989-10-01 00:00:00

abstract：BACKGROUND:Previous studies have shown that low levels of p27(Kip1), an inhibitor of G1 cyclin-dependent kinases, are associated with high aggressiveness and poor prognosis in a variety of cancers. Decreased levels of p27 are caused, at least in part, by acceleration of the rate of its ubiquitin-mediated degradation. I...

journal_title：Cancer

authors： Hershko D,Bornstein G,Ben-Izhak O,Carrano A,Pagano M,Krausz MM,Hershko A

更新日期：2001-05-01 00:00:00

abstract：:The diagnosis of brain metastasis from prostate carcinoma is rarely made antemortem, and has previously been reported only in patients with known extensive metastatic disease of long duration. A case of adenocarcinoma of the prostate presenting as a brain metastasis is described. Current concepts of metastatic spread ...

journal_title：Cancer

authors： Baumann MA,Holoye PY,Choi H

更新日期：1984-10-15 00:00:00

abstract：:The discovery that the human papilloma virus (HPV) is associated with a high and increasing percentage of oropharyngeal squamous cell carcinomas (SCCs) is among the most significant advances in the field of head and neck oncology. HPV-positive oropharyngeal cancer (HPVOPC) has clinical, etiologic, pathologic, and mole...

journal_title：Cancer

authors： Urban D,Corry J,Rischin D

更新日期：2014-05-15 00:00:00

abstract：BACKGROUND:Assessment of the responses of osteosarcoma patients to preoperative chemotherapy is of clinical importance. The purpose of this study was to estimate the accuracy of angiography and thallium-201 scintigraphy, compared with histology, in assessing the responses of patients with osteosarcoma to preoperative c...

journal_title：Cancer

authors： Kunisada T,Ozaki T,Kawai A,Sugihara S,Taguchi K,Inoue H

更新日期：1999-09-15 00:00:00

abstract：BACKGROUND:The efficacy of energy conservation and activity management (ECAM) for fatigue reduction and maintenance of functional performance has never been evaluated in adults with cancer who are undergoing treatment. METHODS:A randomized clinical trial compared an ECAM intervention with a control intervention focuse...

journal_title：Cancer

authors： Barsevick AM,Dudley W,Beck S,Sweeney C,Whitmer K,Nail L

更新日期：2004-03-15 00:00:00

abstract：BACKGROUND:Patient navigation may reduce cancer disparities associated with socioeconomic status (SES) and household factors. This study examined whether these factors were associated with delays in diagnostic resolution among patients with cancer screening abnormalities and whether patient navigation ameliorated these...

journal_title：Cancer

authors： Rodday AM,Parsons SK,Snyder F,Simon MA,Llanos AA,Warren-Mears V,Dudley D,Lee JH,Patierno SR,Markossian TW,Sanders M,Whitley EM,Freund KM

更新日期：2015-11-15 00:00:00

abstract：:In order to determine whether the use of a sequence of chemotherapeutic regimens plus BCG could produce longer durations of remission in adult acute nonlymphocytic leukemia than maintenance therapy with cytosine arabinoside, 6-thioguanine, plus BCG, a randomized study was performed at Washington University. Upon achie...

journal_title：Cancer

authors： Presant CA,Berger NA,Klahr C,Phillips GL

更新日期：1980-07-01 00:00:00

abstract：:As the toll taken by breast cancer continues unabated, screening programs are widely perceived to play a critical role to improve diagnosis and successful treatment. Breast cancer screening programs are increasingly promoted to women; however, the economic implications of mass screening is a subject of much health pol...

journal_title：Cancer

authors： Mushlin AI,Fintor L

更新日期：1992-04-01 00:00:00

abstract：BACKGROUND:Epidermal growth factor (EGF) and EGF-regulated processes play an important role in steroid signal transduction. Comparative analysis of EGF and steroid receptor expression and the sensitivity of early stages of proliferation induction, such as activation of phospholipid turnover to EGF and steroids, may pro...

journal_title：Cancer

authors： Gershtein ES,Shatskaya VA,Kostyleva OI,Ermilova VD,Kushlinsky NE,Krasil'nikov MA

更新日期：1995-12-15 00:00:00

abstract：BACKGROUND:To identify the factors that contribute to poorer colon carcinoma survival rates for African Americans compared with Caucasians, the authors evaluated survival differences based on the histologic grade (differentiation) of the tumor. METHODS:All 169 African Americans and 229 randomly selected non-Hispanic C...

journal_title：Cancer

authors： Alexander D,Jhala N,Chatla C,Steinhauer J,Funkhouser E,Coffey CS,Grizzle WE,Manne U

更新日期：2005-05-15 00:00:00

abstract：BACKGROUND:Telomerase is commonly recognized as an effective anticancer target. The human telomerase reverse transcriptase (hTERT), the rate-limiting component of telomerase, is expressed in most malignant tumors, but it is not found in most normal somatic cells. Here, we report a real-time and noninvasive method to mo...

journal_title：Cancer

authors： Yu ST,Li C,Lü MH,Liang GP,Li N,Tang XD,Wu YY,Shi CM,Chen L,Li CZ,Cao YL,Fang DC,Yang SM

更新日期：2012-04-01 00:00:00

abstract：BACKGROUND:Partial nephrectomy (PN) is recommended for localized T1a (≤4 cm) renal masses and is preferred over radical nephrectomy (RN) for amenable T1b/T2 (>4 cm) tumors. The objective of the current study was to assess overall survival (OS) differences between PN and RN in patients with T1 and T2 renal cell carcinom...

journal_title：Cancer

authors： Ristau BT,Handorf EA,Cahn DB,Kutikov A,Uzzo RG,Smaldone MC

更新日期：2018-10-01 00:00:00

abstract：:The continuity that exists between Hodgkin's disease and the fibrohistiocytoses has only recently been recognized. Four cases are presented that illustrate this phenomenon. The fibrohistiocytic component of the Hodgkin's lesion may lag behind the lymphoreticular component, may be present in equal proportion, or may as...

journal_title：Cancer

authors： Suster S

更新日期：1986-01-15 00:00:00