Abstract:
:In the evaluation of cervical cancer, computed tomography (CT) is used primarily to stage advanced tumors and evaluate for recurrence. Because of reports that CT imaging lacks sensitivity and specificity in the detection of primary tumors and metastatic lesions, its use in these applications has been limited, but recent improvements in CT technology may have increased its accuracy and may broaden its use. At the Second International Conference on Cervical Cancer, held April 11-14, 2002, the limitations of single-detector row CT scanners were compared with the capabilities of new CT technology. Improvements include the introduction of multidetector-row CT scanners, which can produce thinner tissue slices. This technology is needed for detection of parametrial extension, pelvic side-wall disease, extension into the pelvic viscera, lymphadenopathy, local tumor recurrence, and distant metastatic disease. New technology reduces the thickness of each slice to 1-3 mm, improving spatial resolution and making multiplanar imaging possible, which previously was feasible only with magnetic resonance imaging. Studies are needed to assess the use of the improved CT technology in evaluating cervical cancer.
journal_name
Cancerjournal_title
Cancerauthors
Pannu HK,Fishman EKdoi
10.1002/cncr.11684subject
Has Abstractpub_date
2003-11-01 00:00:00pages
2039-43issue
9 Suppleissn
0008-543Xissn
1097-0142journal_volume
98pub_type
杂志文章,评审相关文献
CANCER文献大全abstract::A series of 273 unselected patients with bronchial carcinoma, comprising a total prospective 5-year study from a Swedish county with an observed 5-year survival of 7.0%, is presented. The autopsy rate in deceased patients was 94%. All diagnoses were histologically or cytologically verified. The 5-year survival rates f...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19840515)53:10<2211::aid-cncr282
更新日期:1984-05-15 00:00:00
abstract:BACKGROUND:Poor accrual to cancer clinical trials may contribute to the lower improvement in survival observed for adolescents and young adults (AYAs) (those aged 15-39 years) with cancer. This has been difficult to quantify without reliable mechanisms to link incident cases with study enrollments. Using unique resourc...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.29669
更新日期:2015-12-15 00:00:00
abstract::Meningeal myeloid metaplasia (MM) is very rarely observed in patients with myelofibrosis. We report the occurrence of meningeal MM causing exophthalmus and fever in a patient with myelofibrosis secondary to polycythemia vera. A computerized tomography (CT) scan showed multiple intracranial and intraorbital enhancing m...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19881201)62:11<2346::aid-cncr282
更新日期:1988-12-01 00:00:00
abstract:BACKGROUND:A Phase II prospective trial was performed to study the efficacy of combination therapy with dexamethasone, calcitriol (1,25-dihydroxyvitamin D3), and carboplatin in patients with hormone-refractory prostate cancer (HRPC). Preclinical data from prostate cancer cell lines suggested a synergistic effect of the...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.21982
更新日期:2006-07-15 00:00:00
abstract:BACKGROUND:Most patients with cutaneous squamous cell carcinoma (cSCC) of the head and neck (HN) are at low-risk (<5%) of developing metastatic SCC to regional lymph nodes. However, patients with unfavorable clinicopathologic factors often are under appreciated by clinicians but remain at higher risk for developing met...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.21898
更新日期:2006-06-01 00:00:00
abstract::A brother and sister with Fanconi's anemia, having typical skeletal deformity and characteristic chromosomal breaks in their lymphocytes and who followed the typical clinical course, with progressive bone marrow insufficiency beginning late in the first decade, are described. The natural history of the disease before ...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19841101)54:9<1850::aid-cncr2820
更新日期:1984-11-01 00:00:00
abstract::Neuroblastoma is the most common neoplasm in children less than 1 year of age and has one of the earliest incidence peaks of all childhood cancers. Using birth registration data, a matched case-control study was undertaken to investigate potential prenatal and perinatal risk factors. Ninety-seven neuroblastoma patient...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19880601)61:11<2202::aid-cncr282
更新日期:1988-06-01 00:00:00
abstract:BACKGROUND:The therapeutic impact of tumor resection is poorly defined. Therefore the current study was conducted. METHODS:A retrospective, 2-institutional study was conducted (1991-1994) to compare the treatment results of stereotactic biopsy plus radiation therapy (99 patients; tumor dose: 60 gray [Gy]) with those o...
journal_title:Cancer
pub_type: 杂志文章,多中心研究
doi:
更新日期:1999-11-15 00:00:00
abstract::The possible effect of oral contraceptive (OC) use on the prognosis of established breast cancer was investigated in 154 young women aged 35 and younger. No significant differences were found between the study group of 59 OC users, and the control group of 95 nonusers in age, parity and gravidity, family history of br...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19850401)55:7<1556::aid-cncr2820
更新日期:1985-04-01 00:00:00
abstract::Over the last several decades, significant "new eyes" have been developed that improve the diagnosis, treatment, planning, and monitoring of human cancer: computer tomography (CT), magnetic resonance imaging (MRI) and spectroscopy (MRS), single photon emission computed tomography (SPECT), and positron emission tomogra...
journal_title:Cancer
pub_type: 杂志文章,评审
doi:10.1002/1097-0142(19910215)67:4+<1121::aid-cncr282
更新日期:1991-02-15 00:00:00
abstract::The nuclear DNA content of 98 operable breast cancers was determined by flow cytometric analysis using paraffin-embedded tissue. All patients were on follow-up and failure of treatment or recurrences were identified. DNA ploidy data in the form of ploidy status and DNA index (DI) has been correlated with various clini...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19911215)68:12<2612::aid-cncr282
更新日期:1991-12-15 00:00:00
abstract::Two cases of occult seminoma were observed which showed left-sided lymph node metastases without clinically demonstrable testicular tumors. The peculiar histology of the lymph node metastases, namely PAS-positive tumor cells with clear cytoplasm together with a granulomatous stromal reaction, was highly suggestive of ...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(197907)44:1<245::aid-cncr2820440
更新日期:1979-07-01 00:00:00
abstract:BACKGROUND:The aim of this study was to examine p16(INK4a) protein expression in ThinPrep (Cytyc Corporation, Marlborough, Mass) cervical specimens by using the CINtec p16(INK4a) Cytology Kit (Dako, Glostrup, Denmark). The ability of this assay to accurately identify underlying high-grade lesions was assessed by using ...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.22580
更新日期:2007-04-25 00:00:00
abstract::A study of the effects of local tumor radiation alone (1500R) and cyclophosphamide alone (150 mg/kg) on the experimental solid tumor rat hepatoma 3924A has been completed. Cyclophosphamide was more effective in controlling tumor growth than either radiation or 5-fluorouracil (5-FU) (150 mg/kg) previously reported. Par...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19800601)45:11<2793::aid-cncr282
更新日期:1980-06-01 00:00:00
abstract::This study delineates the temporal relationship between immune complex formation and tumor growth, and provides one possible explanation for host immunosuppression during tumor growth. The authors have studied serial circulating immune complex (CIC) levels and interleukin (IL) elaboration by peripheral blood cells (IL...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19840315)53:6<1373::aid-cncr2820
更新日期:1984-03-15 00:00:00
abstract::Metastatic tumors to the mucosa of the stomach are unusual occurrences that can cause clinical and pathologic problems in diagnosis. The authors report 67 cases from the files of the Veterans Administration Center at Houston. Ten cases were found on endoscopic biopsy and 57 at necropsy. Each patient endoscopically eva...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19900401)65:7<1596::aid-cncr2820
更新日期:1990-04-01 00:00:00
abstract:BACKGROUND:Previous studies have shown that the levels of 15-lipoxygenase 1 (15-LOX-1) and 15-LOX-2 as well as their metabolites 13-S-hydroxyoctadecadienoic acid (13(S)-HODE) and 15(S)-hydroxyeicosatetraenoic acid (15(S)-HETE) are significantly reduced in smokers with non-small cell lung carcinoma (NSCLC). Furthermore,...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.29547
更新日期:2015-09-01 00:00:00
abstract:BACKGROUND:The authors originally demonstrated the tissue-specific expression of the rab3A gene in the mouse brain. In the current study, they analyze the activity of this gene in fresh human tumors associated with neuronal phenotype compared with normal and malignant cells from other origins. METHODS:The authors stud...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19921115)70:10<2552::aid-cncr282
更新日期:1992-11-15 00:00:00
abstract:BACKGROUND:Glioblastoma multiforme (GBM) is the most prevalent and deadly brain tumor. A variety of germline and somatic, genetic and epigenetic alterations at 9p21.3, which encode CDKN2A/CDKN2B tumor suppressor genes, have been isolatedly reported to be associated with GBM risk and prognosis. METHODS:To obtain a comp...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.26250
更新日期:2012-01-01 00:00:00
abstract:BACKGROUND:Neovascularization reportedly is correlated with metastasis, recurrence, and prognosis in some types of tumors. Microvessel quantification in so-called "hot spots" has been studied extensively as the only factor reflecting angiogenesis in various malignant tumors. The objective of this report was to evaluate...
journal_title:Cancer
pub_type: 杂志文章
doi:
更新日期:1998-11-15 00:00:00
abstract::Until recently the prognosis of childhood non-Hodgkin's lymphoma has been poor. A program of combination chemotherapy and involved area radiotherapy was instituted in the Department of Pediatrics at Roswell Park Memorial Institute in 1971. Thirty-one biopsy proven untreated children entered this study. There were 4 St...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(197805)41:5<1997::aid-cncr282041
更新日期:1978-05-01 00:00:00
abstract::One hundred thirty-nine consecutive unselected adults with acute nonlymphoblastic leukemia were treated with a high-dose chemotherapeutic remission-induction regimen consisting of daunomycin (70 mg/m2 IV on days 1, 2, 3), cytosine arabinoside (100 mg/m2 IV every 12 hours), 6-thioguanine (100 mg/m2 orally every 12 hour...
journal_title:Cancer
pub_type: 临床试验,杂志文章
doi:10.1002/1097-0142(19810901)48:5<1073::aid-cncr2820
更新日期:1981-09-01 00:00:00
abstract::In the past all clear cell carcinomas of the female genital tract were thought to arise from mesonephric remnants. Recently increasing evidence has related their origin to müllerian rather than mesonephric epithelium. One of the main reasons that has been advanced to support their mesonephric origin has been their occ...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(197811)42:5<2435::aid-cncr282042
更新日期:1978-11-01 00:00:00
abstract::A total of 289 cases with malignant pleuroperitoneal effusions were reviewed, and their prognosis were analyzed in relation to the following factors: (1) chronologically divided series; (2) previous tumorectomy of the primary lesion; (3) presence or absence of other metastases; (4) site of effusion; (5) site of the pr...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19830101)51:1<136::aid-cncr28205
更新日期:1983-01-01 00:00:00
abstract::The authors studied 11 pediatric intrathoracic neoplasms that share clinicopathologic features and constitute a specific tumor in children. These neoplasms were intrapulmonary, mediastinal, or pleural-based masses. A common histologic feature was the presence of small, primitive cells with blastematous qualities separ...
journal_title:Cancer
pub_type: 杂志文章,评审
doi:10.1002/1097-0142(19881015)62:8<1516::aid-cncr2820
更新日期:1988-10-15 00:00:00
abstract::Because we found it illogical to attempt measurement of nonmeasurable but visible tumors in patients with advanced lung cancer, we devised and used a separate set of response criteria for patients with evaluable, nonmeasurable tumors. Patients with evaluable disease who had obtained a tumor regression after therapy we...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(197909)44:3<1125::aid-cncr282044
更新日期:1979-09-01 00:00:00
abstract::In this study of 2092 women with cancer of the breast, those who had practiced breast self-examination (BSE) had earlier cancer than did those who had not practiced BSE. This was true for both black and white races, all educational and economic levels, each age group, and within each period of delay between first symp...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19810301)47:5<989::aid-cncr28204
更新日期:1981-03-01 00:00:00
abstract:BACKGROUND:Lysosomal proteases are implicated in cancer progression and metastasis. In the current study, using subtraction cloning for genes that are differentially expressed in metastasis, the authors isolated a clone encoding ceroid lipofuscinosis, neuronal 2 (CLN2), which is a lysosomal serine protease defective in...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.21764
更新日期:2006-04-01 00:00:00
abstract::The endocrine action of medroxyprogesterone acetate (MPA) has been claimed to be of a glucocorticoid-like nature. Upon clinical observation, MPA has been shown to improve life quality and overall well-being in patients with advanced breast cancer, renal carcinoma, prostatic carcinoma, and uterine adenocarcinoma. The a...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19901101)66:9<1949::aid-cncr2820
更新日期:1990-11-01 00:00:00
abstract::Six patients with primary seminoma of the mediastinum were treated at the Cancer Control Agency of British Columbia during the period from 1970 to 1982. Primary treatment used was external beam radiotherapy. Only one patient received both radiotherapy and chemotherapy. Tumor dose ranged from 3000 cGy in 16 daily fract...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19850115)55:2<450::aid-cncr28205
更新日期:1985-01-15 00:00:00