Influence of oral contraceptives on the prognosis of breast cancer in young women.

abstract：BACKGROUND:Podoplanin is a mucin-like glycoprotein that is important in lymphangiogenesis but not blood vessel formation. Recent studies suggested a potential role of podoplanin in certain tumor cells. The purpose of the current study was to determine the role of podoplanin in head and neck squamous cell carcinoma (HNS...

journal_title：Cancer

authors： Yuan P,Temam S,El-Naggar A,Zhou X,Liu DD,Lee JJ,Mao L

更新日期：2006-08-01 00:00:00

abstract：BACKGROUND:The National Lung Screening Trial (NLST), which was conducted between 2002 and 2009, demonstrated that screening with low-dose computed tomography (LDCT) reduced lung cancer mortality by 20% among screening-eligible populations compared with chest x-ray. In this article, the authors provide an estimate of th...

journal_title：Cancer

authors： Ma J,Ward EM,Smith R,Jemal A

更新日期：2013-04-01 00:00:00

abstract：BACKGROUND:The association of increasing radiotherapy (RT) dose with reduced biochemical failure (BF) is accepted widely. However, there is little direct evidence that dose escalation has an impact on distant metastasis (DM) or overall mortality (OM). These associations were examined in the current study. METHODS:The ...

journal_title：Cancer

authors： Jacob R,Hanlon AL,Horwitz EM,Movsas B,Uzzo RG,Pollack A

更新日期：2004-02-01 00:00:00

abstract：BACKGROUND:Patients with American Joint Committee on Cancer Stage IV advanced pancreatic carcinoma have been treated by systemic chemotherapy, intraarterial chemotherapy, radiation therapy, and multidisciplinary treatment using a combination of these. However, the outcome has not always been satisfactory. In the curren...

journal_title：Cancer

authors： Homma H,Doi T,Mezawa S,Takada K,Kukitsu T,Oku T,Akiyama T,Kusakabe T,Miyanishi K,Niitsu Y

更新日期：2000-07-15 00:00:00

abstract：:In 186 women with breast cancer, there was a progressive increase in the proportion of axillary nodal involvement as the number of pregnancies increased from zero to two or more (P = 0.026). Logistic regression analysis demonstrated that this effect was independent of the known relationship of age and tumor size to no...

journal_title：Cancer

authors： Lehrer S,Levine E,Savoretti P,Cropley J,Botstein C,Song HK,Mandell L,Shank B

更新日期：1992-02-15 00:00:00

abstract：:The value of image analysis in predicting the malignant potential of oral epithelial lesions showing either hyperplasia or dysplasia was investigated; 5-micron formalin-fixed sections of 16 oral epithelial lesions, of which eight had later transformed to carcinoma and eight had not transformed during a follow-up of 10...

journal_title：Cancer

authors： Abdel-Salam M,Mayall BH,Chew K,Silverman S Jr,Greenspan JS

更新日期：1988-11-01 00:00:00

abstract：BACKGROUND:Clinical trials of monoclonal antibodies in combination with chemotherapy have reported previously unattained response rates in patients with B-cell chronic lymphocytic leukemia (B-CLL); however, the analysis of ZAP-70 protein and/or CD38 may explain better the discordant outcomes independent of treatment. ...

journal_title：Cancer

authors： Del Poeta G,Del Principe MI,Consalvo MA,Maurillo L,Buccisano F,Venditti A,Mazzone C,Bruno A,Gianní L,Capelli G,Lo Coco F,Cantonetti M,Gattei V,Amadori S

更新日期：2005-12-15 00:00:00

abstract：:This communication reports four patients treated with the anthracycline adriamycin and irradiation either concurrently or sequentially, who demonstrated apparent augumentation of radiation reactions. Two of these patients demonstrated the so-called "recall" phenomenon. ...

journal_title：Cancer

authors： Cassady JR,Richter MP,Piro AJ,Jaffe N

更新日期：1975-09-01 00:00:00

abstract：BACKGROUND:The current study was performed to describe frequencies and risk factors of altered oral health and odontogenesis in childhood cancer survivors. METHODS:In total, 9308 survivors who were diagnosed between 1970 and 1986 and 2951 siblings from the Childhood Cancer Survivor Study completed a survey that contai...

journal_title：Cancer

authors： Kaste SC,Goodman P,Leisenring W,Stovall M,Hayashi RJ,Yeazel M,Beiraghi S,Hudson MM,Sklar CA,Robison LL,Baker KS

更新日期：2009-12-15 00:00:00

abstract：BACKGROUND:The possible association between ovarian carcinoma and ovulation-inducing drugs has led to renewed interest in the potential carcinogenic risks of these drugs. In vitro fertilization (IVF) has been linked to multiple pregnancies and possibly congenital malformations. However, to the authors' knowledge the as...

journal_title：Cancer

authors： Lerner-Geva L,Toren A,Chetrit A,Modan B,Mandel M,Rechavi G,Dor J

更新日期：2000-06-15 00:00:00

abstract：:Eighty-one primary ovarian carcinoids and intraovarian metastases from six mid-gut carcinoids were examined for the presence of tumor cells immunoreactive with antisera raised against various neurohormonal peptides, mostly of gastroenteropancreatic (GEP) origin. Twenty of the primary and two of the metastatic carcinoi...

journal_title：Cancer

authors： Sporrong B,Falkmer S,Robboy SJ,Alumets J,Håkanson R,Ljungberg O,Sundler F

更新日期：1982-01-01 00:00:00

abstract：:"Bowen's disease" is a clinical and histologic diagnosis describing the lesions (single or multiple) of cutaneous in situ squamous cell carcinoma. The case of a 54-year-old man with 60 such intra-epidermal carcinomas, and a history of arsenic ingestion, is presented. The patient was sensitized to dinitrochlorobenzene ...

journal_title：Cancer

authors： Raaf JH,Krown SE,Pinsky CM,Cunningham-Rundles W,Safai B,Oettgen HF

更新日期：1976-04-01 00:00:00

abstract：BACKGROUND:The purpose of this study was to identify biologic differences between ovarian clear cell carcinoma and other ovarian adenocarcinomas by comparing the expression of cell cycle regulatory molecules and by analyzing the survival of the patients. METHODS:In 51 cases of epithelial ovarian carcinoma, the express...

journal_title：Cancer

authors： Shimizu M,Nikaido T,Toki T,Shiozawa T,Fujii S

更新日期：1999-02-01 00:00:00

abstract：:Despite few effective therapies, only a small percentage of patients diagnosed with myelodysplastic syndromes (MDS) in the United States are enrolled in prospective, interventional clinical trials. MDS-specific barriers to trial accrual include a high frequency of elderly patients with comorbid conditions, atypical di...

journal_title：Cancer

authors： Steensma DP,Brunner AM,DeZern AE,Garcia-Manero G,Komrokji RS,Odenike OS,Roboz GJ,Savona MR,Stone RM,Sekeres MA

更新日期：2018-12-15 00:00:00

abstract：:A clinicopathologic analysis of 35 cases of lymphocyte predominance Hodgkin's disease (LPHD) was performed, and the relationship between various histologic features and stage at presentation was examined. The series comprised 31 male and 4 female patients with a median age of 32 years. Twenty patients had Ann Arbor St...

journal_title：Cancer

authors： Trudel MA,Krikorian JG,Neiman RS

更新日期：1987-01-01 00:00:00

abstract：:A primitive neuroectodermal tumor of peripheral nerve origin was examined by light and electron microscopy. The lesion arose in association with the S1 nerve root of the lumbosacral plexus in a 22-year-old female. Following a surgical biopsy, the patient received systemic chemotherapy; however, approximately one-and-a...

journal_title：Cancer

authors： Bolen JW,Thorning D

更新日期：1980-12-01 00:00:00

abstract：:Pretreatment biopsy material of 82 cases of follicular lymphoma of lymph node origin was reviewed. According to the amount of small lymphocytes in the parafollicular lymphoid tissue (PSL), tumors were classified: PSL++, abundant lymphocytes with prominent postcapillary venules; PSL+, a number of lymphocytes readily re...

journal_title：Cancer

authors： Ree HJ,Leone LA

更新日期：1978-04-01 00:00:00

abstract：:Data from 133 patients with cancer and suspected compression of the spinal cord or cauda equina was reviewed. Although there were differences in presenting symptoms and signs between the group of 62 patients with compression and the 71 without, no single symptom or sign discriminated adequately between the two groups....

journal_title：Cancer

authors： Bernat JL,Greenberg ER,Barrett J

更新日期：1983-05-15 00:00:00

abstract：BACKGROUND:Preoperative chemoradiation improves survival in esophageal and gastroesophageal junction (GEJ) cancer. We evaluated irinotecan and cisplatin as induction chemotherapy followed by concurrent chemoradiation in esophageal cancer. METHODS:Patients with uT1N1M0 or uT2-4NanyM0 resectable squamous cancer or adeno...

journal_title：Cancer

authors： Ilson DH,Minsky BD,Ku GY,Rusch V,Rizk N,Shah M,Kelsen DP,Capanu M,Tang L,Campbell J,Bains M

更新日期：2012-06-01 00:00:00

abstract：BACKGROUND:Telomerase is a ribonucleoprotein that maintains telomeric base pair repeats at the ends of mammalian chromosomes during DNA replication. Telomerase is expressed in various human tumors, some normal tissues, and immortalized cell lines. The assay of telomerase activity has potential as an adjunct for cancer ...

journal_title：Cancer

authors： Mu XC,Brien TP,Ross JS,Lowry CV,McKenna BJ

更新日期：1999-04-25 00:00:00

abstract：:Eleven patients with advanced soft tissue sarcoma were treated with whole body hyperthermia (41.8 degrees C-43.0 degrees C) for 2 hours, doxorubicin (45 mg/m2) at the beginning of peak temperature and cyclophosphamide (1000 mg/m2) 6 hours after doxorubicin. Warming was accomplished with a nylon and vinyl mesh water pe...

journal_title：Cancer

authors： Gerad H,van Echo DA,Whitacre M,Ashman M,Helrich M,Foy J,Ostrow S,Wiernik PH,Aisner J

更新日期：1984-06-15 00:00:00

abstract：:Seventeen patients were given DTIC, 200 mg/m2/day in five-day courses every four to six weeks. In four patients (stage II) treated on an adjuvant basis, tumor recurrence has been verified in three. Four of the palliatively treated patients were also given DTIC by regional intra-arterial infusion with minimal positive ...

journal_title：Cancer

authors： Jönsson PE,Agrup G,Arnbjörnsson E,Hafström L,Rorsman H

更新日期：1980-01-15 00:00:00

abstract：BACKGROUND:Although it is believed that p53 suppressor gene mutations, compared with mutations in the K-ras oncogene, occur at a later stage of colorectal tumorigenesis, the distribution of these genetic alterations at an early stage remains poorly characterized. METHODS:The authors analyzed the immunoreactivity for p...

journal_title：Cancer

authors： Hosaka S,Aoki Y,Akamatsu T,Nakamura N,Hosaka N,Kiyosawa K

更新日期：2002-01-01 00:00:00

abstract：:Seven hundred ninety-five patients were adenocarcinomas of the proximal colon were reviewed. Two hundred forty-five patients presented with disseminated disease at the time of diagnosis, and were analyzed to identify mechanisms and sites of disease spread. Five hundred fifty patients underwent radical resection, and w...

journal_title：Cancer

authors： Russell AH,Tong D,Dawson LE,Wisbeck W

更新日期：1984-01-15 00:00:00

abstract：:This study explores the patterns of recurrence after "curative" operation for colorectal cancer. For an 11-year period, 1960-1971, 281 evaluable patients were resected at the Peter Bent Brigham Hospital. Crude five-year survival in these patients was 49%, but only 10% of those with recurrence lived five years. A total...

journal_title：Cancer

authors： Olson RM,Perencevich NP,Malcolm AW,Chaffey JT,Wilson RE

更新日期：1980-06-15 00:00:00

abstract：BACKGROUND:DNA ploidy and S-phase fraction measured by DNA flow cytometry were shown to correlate with several clinicopathologic characteristics in several types of tumors. METHODS:DNA flow cytometry was performed on 329 samples (164 normal mucosa, 165 tumors) obtained from 165 patients (112 men) with stomach cancer, ...

journal_title：Cancer

authors： Lee KH,Lee JS,Suh C,Ahn MJ,Kim SW,Doh BS,Min YI,Kim BS,Park KC,Lee IC

更新日期：1993-09-15 00:00:00

abstract：BACKGROUND:Through this study, the authors sought to investigate the biologic and immunologic effects of preoperative trastuzumab in patients with ductal carcinoma in situ (DCIS) of the breast. METHODS:Patients with DCIS were enrolled in this open-label phase 2 trial and tested for HER2. Trastuzumab was given by intra...

journal_title：Cancer

authors： Kuerer HM,Buzdar AU,Mittendorf EA,Esteva FJ,Lucci A,Vence LM,Radvanyi L,Meric-Bernstam F,Hunt KK,Symmans WF

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:Since mid-1987, 29 patients with invasive transitional cell carcinoma of the urinary bladder (T1-3 N0-X M0) were treated with concurrent radiation therapy (RT) (target dose [TD], 62-66 Gy) 1.8-2.0 Gy/day for 5 days a week with a break in the middle of treatment of 2-3 weeks and vinblastine weekly 2 mg/5-12 h...

journal_title：Cancer

authors： Kragelj B,Jereb B,Kragelj L,Stanonik M

更新日期：1992-12-15 00:00:00

abstract：BACKGROUND:The authors previously demonstrated that never-smokers with stage IIIB/IV nonsmall cell lung cancer (NSCLC) lived 50% longer than former/current smokers. This observation persisted after adjusting for age, performance status, and sex. In this study, the authors hypothesized that smoking-dependent differences...

journal_title：Cancer

authors： Paik PK,Johnson ML,D'Angelo SP,Sima CS,Ang D,Dogan S,Miller VA,Ladanyi M,Kris MG,Riely GJ

更新日期：2012-12-01 00:00:00

abstract：BACKGROUND:Chemotherapy-induced nausea and vomiting remain common, distressing side effects of chemotherapy. It has been reported that acupressure prevents chemotherapy-induced nausea in adults, but it has not been well studied in children. METHODS:In this multicenter, prospective, randomized, single-blind, sham-contr...

journal_title：Cancer

authors： Dupuis LL,Kelly KM,Krischer JP,Langevin AM,Tamura RN,Xu P,Chen L,Kolb EA,Ullrich NJ,Sahler OJZ,Hendershot E,Stratton A,Sung L,McLean TW

更新日期：2018-03-15 00:00:00