Doxorubicin, cyclophosphamide, and whole body hyperthermia for treatment of advanced soft tissue sarcoma.

abstract：:A bolus intravenous dose of 5-fluorouracil of 600 mg/M2 was added exactly 1 hour after methotrexate administration in an established combination program including bleomycin and cisplatin for advanced squamous cell cancer of the head and neck. Results were no better than those observed previously with the three drugs, ...

journal_title：Cancer

authors： Vogl SE,Komisar A,Kaplan BH,Engstrom PF,Kasule OH,Stolbach L,Lerner H,Muggia F

更新日期：1986-02-15 00:00:00

abstract：:This study examines the interrelationships of depth of penetration, tumor size, and the number of positive nodes in Dukes C colorectal cancer. The results indicated that depth of tumor penetration was related to both tumor size and the number of positive regional lymph nodes. Tumors with positive nodes which failed to...

journal_title：Cancer

authors： Wolmark N,Fisher ER,Wieand HS,Fisher B

更新日期：1984-06-15 00:00:00

abstract：:A family with histopathologically proven intraocular malignant melanoma involving two generations is reported. A member of third generation was likely involved by history. Intraocular malignant melanoma, its familial occurrence, its occurrence with multiple malignancies, and its relationship to multiple malignancies o...

journal_title：Cancer

authors： Green GJ,Hong WK,Everett JR,Bhutani R,Amick RM

更新日期：1978-06-01 00:00:00

abstract：:Malignant schwannomas with rhabdomyoblastic differentiation have been termed malignant "Triton" tumors (MTT). To define the natural history of MTT, we have analyzed our experience (9 cases, the largest series reported) in combination with the 27 previously described in the literature (total 36 cases). This study was i...

journal_title：Cancer

authors： Brooks JS,Freeman M,Enterline HT

更新日期：1985-06-01 00:00:00

abstract：:Seven hundred ninety-five patients were adenocarcinomas of the proximal colon were reviewed. Two hundred forty-five patients presented with disseminated disease at the time of diagnosis, and were analyzed to identify mechanisms and sites of disease spread. Five hundred fifty patients underwent radical resection, and w...

journal_title：Cancer

authors： Russell AH,Tong D,Dawson LE,Wisbeck W

更新日期：1984-01-15 00:00:00

abstract：BACKGROUND:Angiotropic large cell lymphoma (ALCL) is characterized by the intravascular proliferation of malignant lymphoid cells in small and medium-sized blood vessels. In the current study, the authors report an unusual case in which the initial presentation of the ALCL was that of superior vena cava (SVC) syndrome....

journal_title：Cancer

authors： Savarese DM,Zavarin M,Smyczynski MS,Rohrer MJ,Hutzler MJ

更新日期：2000-12-15 00:00:00

abstract：BACKGROUND:Posttreatment prostate biopsy is a method of assessing local control after irradiation for prostate carcinoma. An analysis of the effect of disease- and treatment-related factors on biopsy results after prostate brachytherapy was performed to aid in patient selection and treatment optimization. METHODS:Two ...

journal_title：Cancer

authors： Stock RG,Stone NN,Kao J,Iannuzzi C,Unger P

更新日期：2000-10-15 00:00:00

abstract：:The long-term effect of cisplatin on renal function was studied in a follow-up investigation, 16 to 52 months after chemotherapy in 22 patients with disseminated nonseminomatous testicular cancer. The median cumulated cisplatin dose was 452 mg/m2 (range, 275-650 mg/m2). Prehydration with isotonic saline secured diures...

journal_title：Cancer

authors： Fjeldborg P,Sørensen J,Helkjaer PE

更新日期：1986-11-15 00:00:00

abstract：BACKGROUND:Low-grade gliomas (LGGs) and low-grade glioneuronal tumors (LGGNTs) diagnosed during the first year of life carry unique clinical characteristics and challenges in management. However, data on the treatment burden, outcomes, and morbidities are lacking. METHODS:A retrospective study of LGGs and LGGNTs diagn...

journal_title：Cancer

authors： Liu APY,Hastings C,Wu S,Bass JK,Heitzer AM,Ashford J,Vestal R,Hoehn ME,Ghazwani Y,Acharya S,Conklin HM,Boop F,Merchant TE,Gajjar A,Qaddoumi I

更新日期：2019-04-01 00:00:00

abstract：:Desmosomes, gap junctions and tight junctions are intercellular specializations which have been described in human meningiomas. We report, in five of five meningiomas, including a pulmonary metastasis from a malignant intracranial meningioma, a fourth type of intercellular specialization which is similar to but not id...

journal_title：Cancer

authors： Copeland DD,Bell SW,Shelburne JD

更新日期：1978-06-01 00:00:00

abstract：:Six patients with Hodgkin's disease (HD) and demonstrable serum antibodies to human immunodeficiency virus (HIV) and two additional patients with HD belonging to HIV-associated high-risk groups but with negative HIV serology were studied. All patients were men and ranged in age from 21 to 45 years. The HIV risk factor...

journal_title：Cancer

authors： Pelstring RJ,Zellmer RB,Sulak LE,Banks PM,Clare N

更新日期：1991-04-01 00:00:00

abstract：BACKGROUND:Acute myeloid leukemia (AML) with t(6;11)(q27;q23) is a well established but rare entity, and few studies have reported the full clinical, hematologic, and outcome data of patients with this disease. METHODS:To characterize the features of t(6;11) AML, the authors searched the Cancer and Leukemia Group B (C...

journal_title：Cancer

authors： Blum W,Mrózek K,Ruppert AS,Carroll AJ,Rao KW,Pettenati MJ,Anastasi J,Larson RA,Bloomfield CD

更新日期：2004-09-15 00:00:00

abstract：BACKGROUND:The American Cancer Society has sponsored community-based, low-cost, Breast Cancer Detection Awareness Projects throughout the United States. The authors hypothesized that these projects tend to exclude minorities and women of lower socioeconomic status--groups with a higher incidence of late-stage disease. ...

journal_title：Cancer

authors： Roetzheim RG,Vandurme DJ,Brownlee HJ,Herold AH,Pamies RJ,Woodard L,Blair C

更新日期：1992-09-01 00:00:00

abstract：BACKGROUND:Chemoradiotherapy has become the standard of care for head and neck squamous cell carcinoma; however, those patients often experience multiple treatment-related symptoms or symptom clusters. Two symptom clusters have been identified for this population. Little is known about the risk factors of these symptom...

journal_title：Cancer

authors： Xiao C,Hanlon A,Zhang Q,Movsas B,Ang K,Rosenthal DI,Nguyen-Tan PF,Kim H,Le Q,Bruner DW

更新日期：2014-03-15 00:00:00

abstract：BACKGROUND:Ligand activation of peroxisome proliferator-activated receptor gamma (PPARgamma) results in the inhibition of proliferation of various cancer cells. The aim of this study is to investigate the mechanisms of cell growth inhibition of hepatocellular carcinoma (HCC) cell lines by the PPARgamma ligand, troglita...

journal_title：Cancer

authors： Yoshizawa K,Cioca DP,Kawa S,Tanaka E,Kiyosawa K

更新日期：2002-11-15 00:00:00

abstract：:A patient is presented who developed a peritoneal malignant mesothelioma in association with severe persistent and recurrent diverticulitis. The case is unusual in that a spectrum of mesothelial proliferation was documented beginning initially as benign foci of mesothelial proliferation and passing through a stage of ...

journal_title：Cancer

authors： Riddell RH,Goodman MJ,Moossa AR

更新日期：1981-07-01 00:00:00

abstract：BACKGROUND:Failure to obtain the requisite follow-up of patients with abnormal mammograms may delay cancer diagnosis and impact outcome. Up to 20% of women do not receive timely recommended follow-up. The current study tested the accuracy of the linkage of payer claims and clinical data to identify the appropriate trea...

journal_title：Cancer

authors： Eberl MM,Watroba N,Reinhardt M,Pomerantz J,Serghany J,Broffman G,Fox CH,Mahoney MC,Edge SB

更新日期：2007-08-01 00:00:00

abstract：BACKGROUND:Thymic malignancies are rare tumors. The insulin-like growth factor-1 (IGF-1)/IGF-1 receptor (IGF-1R) system is involved in the development of the thymus. IGF-1R expression in thymic epithelial malignancies is unknown. METHODS:The authors investigated the expression of IGF-1R and phosphorylated AKT serine 4...

journal_title：Cancer

authors： Zucali PA,Petrini I,Lorenzi E,Merino M,Cao L,Di Tommaso L,Lee HS,Incarbone M,Walter BA,Simonelli M,Roncalli M,Santoro A,Giaccone G

更新日期：2010-10-15 00:00:00

abstract：BACKGROUND:Although the anticancer effects of progesterone therapy for patients with endometrial carcinoma are widely acknowledged, a detailed assessment of the resultant morphologic alterations in tumor tissue kinetics has hitherto been lacking. METHODS:Biopsy and hysterectomy specimens of 14 endometrial carcinomas (...

journal_title：Cancer

authors： Saegusa M,Okayasu I

更新日期：1998-07-01 00:00:00

abstract：BACKGROUND:Thalidomide is an antiangiogenic agent with immune modulating potential. The objective of this study was to determine response rates among women who were treated for recurrent ovarian cancer using topotecan with or without thalidomide. METHODS:Women were enrolled in this multicenter, prospective, randomized...

journal_title：Cancer

authors： Downs LS Jr,Judson PL,Argenta PA,Ghebre R,Geller MA,Bliss RL,Boente MP,Nahhas WA,Abu-Ghazaleh SZ,Chen MD,Carson LF

更新日期：2008-01-15 00:00:00

abstract：:The incidence of gastric cancer has declined markedly in Finland during the last 4 decades. To document the changes caused by that in the ratio of the intestinal type (IT) to the diffuse type (DT) of gastric carcinoma we compared the 367 cases diagnosed from southwestern Finland at the Department of Pathology, Turku U...

journal_title：Cancer

authors： Laurén PA,Nevalainen TJ

更新日期：1993-05-15 00:00:00

abstract：BACKGROUND:The demonstration of the monoclonality of immunoglobulin heavy chain (IgH) gene rearrangement is an indispensable method for the diagnosis of B-cell lymphoma as well as histocytochemical analysis. For the detection of IgH gene rearrangement, the extraction of DNA from a homogenous cell population is necessar...

journal_title：Cancer

authors： Orba Y,Tanaka S,Nishihara H,Kawamura N,Itoh T,Shimizu M,Sawa H,Nagashima K

更新日期：2003-08-25 00:00:00

abstract：BACKGROUND:Cisplatin (CDDP) administration concomitant with radiotherapy (RT) for the treatment of locally advanced cervical cancer has evolved from an inpatient 5-day every 21-day regimen to a weekly outpatient regimen. This study was designed to test for differences in progression-free survival (PFS) and toxicity bet...

journal_title：Cancer

authors： Einstein MH,Novetsky AP,Garg M,Hailpern SM,Huang GS,Glueck A,Fields AL,Kalnicki S,Goldberg GL

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:Cisplatin is one of the single drugs that has shown the best documented effect in treating patients with locally recurrent or metastatic urothelial cancer. To the authors' knowledge, the effect of the combination of different platinum analogues in treating transitional cell carcinoma has not been evaluated p...

journal_title：Cancer

authors： Sengeløv L,Nielsen OS,Kamby C,von der Maase H

更新日期：1995-11-15 00:00:00

abstract：:A case of bronchogenic carcinoma with polyostotic metastatasis to the phalanges is presented. The literature has also been extensively reviewed. ...

journal_title：Cancer

authors： Nagendran T,Patel MN,Gaillard WE,Imm F,Walker M

更新日期：1980-02-15 00:00:00

abstract：:There is a growing body of basic science and epidemiologic evidence to support a research thrust to determine whether several natural or synthetic agents, given alone or together, can lower cancer incidence. Candidate agents include analogs of vitamin A and the vitamin A precursor, beta-carotene, vitamins C and E, and...

journal_title：Cancer

authors： Malone WF,Kelloff GJ,Pierson H,Greenwald P

更新日期：1987-08-01 00:00:00

abstract：BACKGROUND:The presence of single-nucleotide polymorphisms (SNPs) within the 3'-untranslated regions of genes could affect the binding between a microRNA (miRNA) and its target, with consequences on gene expression regulation. Considering the important role of miRNAs in carcinogenesis, it is hypothesized here that thes...

journal_title：Cancer

authors： Landi D,Gemignani F,Pardini B,Naccarati A,Garritano S,Vodicka P,Vodickova L,Canzian F,Novotny J,Barale R,Landi S

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND:Approximately 30% of breast carcinoma patients with negative lymph nodes die of their disease. Biologic markers such p53 protein and c-erb B-2 have been related to tumor progression, but their prognostic value remains controversial. METHODS:Two large series of a total of 613 lymph node negative breast carci...

journal_title：Cancer

authors： Reed W,Hannisdal E,Boehler PJ,Gundersen S,Host H,Marthin J

更新日期：2000-02-15 00:00:00

abstract：BACKGROUND:Preoperative chemoradiation improves survival in esophageal and gastroesophageal junction (GEJ) cancer. We evaluated irinotecan and cisplatin as induction chemotherapy followed by concurrent chemoradiation in esophageal cancer. METHODS:Patients with uT1N1M0 or uT2-4NanyM0 resectable squamous cancer or adeno...

journal_title：Cancer

authors： Ilson DH,Minsky BD,Ku GY,Rusch V,Rizk N,Shah M,Kelsen DP,Capanu M,Tang L,Campbell J,Bains M

更新日期：2012-06-01 00:00:00

abstract：:High dose methotrexate followed by citrovorum factor reversal has been utilized in twenty-six patients with advanced cancer. Four of 10 patients with head and neck cancer had an objective response. One of 7 patients with metastatic osteosarcoma to the lungs had stabilization with twenty treatments over 23 months. One ...

journal_title：Cancer

authors： Ambinder EP,Perloff M,Ohnuma T,Biller HF,Holland JF

更新日期：1979-04-01 00:00:00