Epidemiology of intestinal and diffuse types of gastric carcinoma. A time-trend study in Finland with comparison between studies from high- and low-risk areas.

Abstract:

:The incidence of gastric cancer has declined markedly in Finland during the last 4 decades. To document the changes caused by that in the ratio of the intestinal type (IT) to the diffuse type (DT) of gastric carcinoma we compared the 367 cases diagnosed from southwestern Finland at the Department of Pathology, Turku University, from 1950-1959 and 1076 cases from 1980-1989. IT virtually disappeared in the male and female populations younger than 50 years, and in patients younger than 60 years, DT became more common than IT (P < 0.001). The transitional age, the time at which IT exceeds DT in frequency, shifted by 20 years to older age groups. In patients older than 60 years, IT remained the dominant type, but the ratio of IT to DT (IT:DT) decreased in men from 3.8 to 2.1 (P < 0.05) and in women from 4.4 to 2.1 (P < 0.001). No decrease in the frequency of DT could be demonstrated in the material studied. The disappearance of the male-dominant IT in the younger male population changed the male-to-female ratio of patients reported to the Finnish Cancer Registry. When the ratio IT:DT in Finland was compared with the ratios reported by the authors in data from other continents and by other investigators, regional variations in basal level of IT:DT emerged. This phenomenon seems to be based on the differing genetic susceptibility to DT of various races. The decrease of IT, seen in reports from regions with declining incidence of gastric carcinoma, seems to be connected to a diminished rate of severe chronic gastritis.

journal_name

Cancer

journal_title

Cancer

authors

Laurén PA,Nevalainen TJ

doi

10.1002/1097-0142(19930515)71:10<2926::aid-cncr282

subject

Has Abstract

pub_date

1993-05-15 00:00:00

pages

2926-33

issue

10

eissn

0008-543X

issn

1097-0142

journal_volume

71

pub_type

杂志文章

相关文献

CANCER文献大全
  • Risk of mortality in patients with cancer who experience febrile neutropenia.

    abstract:BACKGROUND:Febrile neutropenia (FN) is a serious and potentially life-threatening condition that may develop in patients with cancer who receive myelosuppressive chemotherapy. The risk of mortality from FN is not well characterized in current clinical practice. METHODS:Patients with cancer who were receiving chemother...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.25332

    authors: Lyman GH,Michels SL,Reynolds MW,Barron R,Tomic KS,Yu J

    更新日期:2010-12-01 00:00:00

  • Treatment of metastatic breast cancer with aminoglutethimide.

    abstract::Seventy-three women with metastatic breast cancer were treated with aminoglutethimide and dexamethasone. No complete responses occurred. Ten patients (16%) achieved partial responses (mean duration, 12 months). The proportions of patients responding by disease site were breast (50%), nodes (33%), skin (23%), bone (16%...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19810415)47:8<1954::aid-cncr2820

    authors: Asbury RF,Bakemeier RF,Fölsch E,McCune CS,Savlov E,Bennett JM

    更新日期:1981-04-15 00:00:00

  • The occurrence of soft tissue sarcomas in three siblings with Werner's syndrome.

    abstract::Werner's syndrome, a relatively rare and autosomal recessive disorder, is well known to be characterized by a high frequency of malignant neoplasm. The occurrence of familial neoplasm in patients with this condition, however, has been recorded only once before in the literature. Reported are the findings with regard t...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19841201)54:11<2580::aid-cncr282

    authors: Usui M,Ishii S,Yamawaki S,Hirayama T

    更新日期:1984-12-01 00:00:00

  • Acinic cell adenocarcinoma of minor salivary glands.

    abstract::Nine cases identified as acinic cell adenocarcinoma of minor salivary glands from the files of the Armed Forces Institute of Pathology and the Department of Pathology, Temple University School of Dentistry were studied to determine the clinical and histomorphologic parameters of this lesion. One case was examined ultr...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(197808)42:2<678::aid-cncr2820420

    authors: Chen SY,Brannon RB,Miller AS,White DK,Hooker SP

    更新日期:1978-08-01 00:00:00

  • Correlation of chromosome abnormalities with clinical characteristics in thyroid lymphoma.

    abstract::Karyotypes from seven patients with thyroid lymphoma were studied before treatment. When the cytogenetic results were correlated with the clinical data, it became evident that there are two distinct groups of patients with thyroid lymphoma. In a group of patients with solely numerical abnormalities the disease is asso...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19890301)63:5<873::aid-cncr28206

    authors: Taniwaki M,Nishida K,Misawa S,Takino T,Abe T,Aozasa K,Katagiri S,Yonezawa T,Matsuzuka F,Kuma K

    更新日期:1989-03-01 00:00:00

  • An analysis of abnormalities of the retinoblastoma gene in human ovarian and endometrial carcinoma.

    abstract::The altered expression of the human retinoblastoma (RB) gene has been demonstrated to play an important role in the pathogenesis of RB and other tumors. To determine whether the RB gene might be involved in the pathogenesis of human ovarian and endometrial cancer, DNA from 24 human ovarian tumors, 3 normal ovaries, 3 ...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19901115)66:10<2150::aid-cncr282

    authors: Sasano H,Comerford J,Silverberg SG,Garrett CT

    更新日期:1990-11-15 00:00:00

  • Utilization of a human tumor cloning system to monitor for bone marrow involvement in children with non-hodgkin's lymphoma.

    abstract::The objective of this study was to evaluate the sensitivity of two methods for determining bone marrow involvement with non-Hodgkin's lymphoma. These methods were histologic review of bone marrow aspirates, and clot sections versus in vitro growth of lymphoma colonies on soft agar. Forty-two bone marrow aspirates were...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19840415)53:8<1724::aid-cncr2820

    authors: Smith SD,Kisker S,Bush L,Trueworthy RC

    更新日期:1984-04-15 00:00:00

  • Long-term follow-up of patients with newly diagnosed acute myeloid leukemia treated at the University of Texas M.D. Anderson Cancer Center.

    abstract:BACKGROUND:Chemotherapy is known to cure a small minority of patients with acute myeloid leukemia (AML). Less is known about the risk of such patients developing subsequent cancers or about their ability to return to work. METHODS:The authors analyzed outcomes among 1892 patients who received treatment for newly diagn...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/(sici)1097-0142(19971201)80:11+<2176::aid-

    authors: Estey E,deLima M,Strom S,Pierce S,Freireich EJ,Keating MJ

    更新日期:1997-12-01 00:00:00

  • Evaluation and limitations of the lipid-associated sialic acid test for the detection of human cancer.

    abstract::Previous studies and those of the authors have reported about raised levels of lipid-bound sialic acid (LSA) in sera of patients with various neoplasms. Most authors have used the method of Katopodis and Stock for isolating serum LSA. Because of the discrepancy of the amount of extracted LSA with the content of pure g...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19891201)64:11<2279::aid-cncr282

    authors: Voigtmann R,Pokorny J,Meinshausen A

    更新日期:1989-12-01 00:00:00

  • Angioimmunoblastic lymphadenopathy progressing to immunoblastic lymphoma with prominent gastric involvement.

    abstract::Two unusual cases of angioimmunoblastic lymphadenopathy with dysproteinemia (AILD), with progression to immunoblastic lymphoma (IL) and prominent gastric involvement are presented, and detailed immunohistologic studies described. In one case, Bence Jones proteinuria of the kappa type was observed during the course of ...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19821115)50:10<2089::aid-cncr282

    authors: Bauer TW,Mendelsohn G,Humphrey RL,Mann RB

    更新日期:1982-11-15 00:00:00

  • Metastatic patterns at autopsy in patients with ovarian carcinoma.

    abstract:BACKGROUND:Previously published studies concerning autopsy findings in ovarian cancer failed to consider the broad differences in factors that influence the course of disease. Furthermore, those studies were conducted when the currently accepted standards in diagnostics and therapy had not been fully established. The o...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.22919

    authors: Güth U,Huang DJ,Bauer G,Stieger M,Wight E,Singer G

    更新日期:2007-09-15 00:00:00

  • Chemotherapy of large intestinal carcinoma. Current results and future prospects.

    abstract::Chemotherapy of advanced stages of large bowel cancer has until recently made little progress since the introduction of 5-FU 16 years ago. While survival is improved for patients who respond, 5-FU alone has made little impact on life span of the overall population of patients. Mitomycin-C and the chloroethyl nitrosour...

    journal_title:Cancer

    pub_type: 临床试验,杂志文章

    doi:10.1002/1097-0142(197512)36:6<2418::aid-cncr282036

    authors: Schein PS,Kisner D,MacDonald JS

    更新日期:1975-12-01 00:00:00

  • Clinicopathologic features associated with efficacy and long-term survival in metastatic melanoma patients treated with BRAF or combined BRAF and MEK inhibitors.

    abstract:BACKGROUND:The degree of response and the duration of survival of patients treated with mitogen-activated protein kinase (MAPK) inhibitors are highly variable. Whether baseline clinicopathologic factors can predict the clinical course with treatment is largely unknown. METHODS:For 142 consecutive immunotherapy- and MA...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.29586

    authors: Menzies AM,Wilmott JS,Drummond M,Lo S,Lyle M,Chan MM,Thompson JF,Guminski A,Carlino MS,Scolyer RA,Kefford RF,Long GV

    更新日期:2015-11-01 00:00:00

  • Bone mineral density in young adult survivors of acute lymphoblastic leukemia.

    abstract:BACKGROUND:The purpose of the current study was to determine the prevalence of low bone mineral density (BMD) (ie, osteopenia) and identify factors associated with low BMD in young adult survivors of childhood acute lymphoblastic leukemia (ALL). METHODS:Dual energy x-ray absorptiometry was used to evaluate BMD in 74 r...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.23912

    authors: Thomas IH,Donohue JE,Ness KK,Dengel DR,Baker KS,Gurney JG

    更新日期:2008-12-01 00:00:00

  • The role of serum CEA as a prognostic indicator in stage II and III breast cancer patients treated with adjuvant chemotherapy.

    abstract::Carcinoembryonic antigen (CEA) values in 529 patients treated in two consecutive adjuvant chemotherapy protocols were analyzed to determine if CEA values correlated with disease-free status or prognostic utility. CEA values were evaluated preoperatively, before chemotherapy, at the conclusion of chemotherapy, and duri...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19890301)63:5<828::aid-cncr28206

    authors: Theriault RL,Hortobagyi GN,Fritsche HA,Frye D,Martinez R,Buzdar AU

    更新日期:1989-03-01 00:00:00

  • Impact of state-specific Medicaid reimbursement and eligibility policies on receipt of cancer screening.

    abstract:BACKGROUND:Although state Medicaid programs cover cancer screening, Medicaid beneficiaries are less likely to be screened for cancer and are more likely to present with tumors of an advanced stage than are those with other insurance. The current study was performed to determine whether state Medicaid eligibility and re...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.28704

    authors: Halpern MT,Romaire MA,Haber SG,Tangka FK,Sabatino SA,Howard DH

    更新日期:2014-10-01 00:00:00

  • Malignant melanoma metastatic to the breast: a report of seven cases diagnosed by fine-needle aspiration cytology.

    abstract:BACKGROUND:Metastases to the breast from extramammary primary tumors are uncommon. Malignant melanoma is one of the most common neoplasms to secondarily involve the mammary parenchyma. METHODS:Seven cases of malignant melanoma metastatic to the breast diagnosed by fine-needle aspiration biopsy are presented. RESULTS:...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/(sici)1097-0142(19980625)84:3<160::aid-cnc

    authors: Cangiarella J,Symmans WF,Cohen JM,Goldenberg A,Shapiro RL,Waisman J

    更新日期:1998-06-25 00:00:00

  • DNA methylation of genes linked with retinoid signaling in gastric carcinoma: expression of the retinoid acid receptor beta, cellular retinol-binding protein 1, and tazarotene-induced gene 1 genes is associated with DNA methylation.

    abstract:BACKGROUND:Hypermethylation of CpG islands has been associated with silencing of various tumor suppressor genes, and the retinoid acid receptor beta (RARbeta), cellular retinol-binding protein 1 (CRBP1), and tazarotene-induced gene 1 (TIG1) genes have been associated with retinoic acid signaling. To the authors' knowle...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.21392

    authors: Shutoh M,Oue N,Aung PP,Noguchi T,Kuraoka K,Nakayama H,Kawahara K,Yasui W

    更新日期:2005-10-15 00:00:00

  • Sarcomas of the great vessels. A clinicopathologic study.

    abstract:BACKGROUND:There are few reports comparing the clinicopathologic features of sarcomas of the aorta (SA), sarcomas of the inferior vena cava (SIVC), and sarcomas of the pulmonary artery (SPA). METHODS:The authors retrospectively reviewed 11 SA, 16 SIVC, and 16 SPA, and compared clinical, pathologic, and immunohistochem...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19930301)71:5<1761::aid-cncr2820

    authors: Burke AP,Virmani R

    更新日期:1993-03-01 00:00:00

  • Sequential cyclophosphamide and doxorubicin for induction of complete remission in children with disseminated neuroblastoma.

    abstract::When 70 children with disseminated neuroblastoma were treated for 4 months with a course of cyclophosphamide and doxorubicin (Adriamycin) 35 (52%) of 68 assessable patients achieved complete remissions, 13 had partial responses, and 20 had either less than a 50% regression of tumor or evidence of tumor progression. Of...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19811115)48:10<2310::aid-cncr282

    authors: Green AA,Hayes FA,Hustu HO

    更新日期:1981-11-15 00:00:00

  • Parental distress and desire for information regarding long-term implications of pediatric cancer treatment.

    abstract:BACKGROUND:Parents of children with cancer have unmet information needs regarding future limitations resulting from cancer or its treatment. Prior research has demonstrated that, in early care discussions, clinicians focus on the acute effects of therapy rather than long-term limitations, partly due to worries of causi...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.31772

    authors: Greenzang KA,Cronin AM,Kang TI,Mack JW

    更新日期:2018-12-01 00:00:00

  • Focal, high dose, and fractionated modified stereotactic radiation therapy for lung carcinoma patients: a preliminary experience.

    abstract:BACKGROUND:Stereotactic radiation therapy is highly effective in the treatment of small brain metastases, regardless of the histology. This suggests that small extracranial malignancies may be curable with similar radiation therapy. The authors developed a novel treatment unit for administering such therapy. METHODS:T...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/(sici)1097-0142(19980315)82:6<1062::aid-cn

    authors: Uematsu M,Shioda A,Tahara K,Fukui T,Yamamoto F,Tsumatori G,Ozeki Y,Aoki T,Watanabe M,Kusano S

    更新日期:1998-03-15 00:00:00

  • Trichosporon sepsis and leukemia.

    abstract::Trichosporon cutaneum is a fungus known to cause superficial nodules over the distal third of hair shafts, mainly scalp hair, and to produce a clinical entity known as piedra. This superficial mycosis occurs mostly in temperate and tropical regions and is rarely seen in North America. Trichosporon cutaneum spesis is d...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(197509)36:3<1106::aid-cncr282036

    authors: Rivera R,Cangir A

    更新日期:1975-09-01 00:00:00

  • Late recurrence of surgically removed prolactinomas.

    abstract::The authors observed the clinical course of 24 women with surgically removed prolactinomas for a mean postoperative interval of 62 months. The frequency of late tumor recurrence and probable factors responsible for the recurrence were investigated. Hyperprolactinemia recurred in 4 of 13 patients with microadenomas (31...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19860615)57:12<2422::aid-cncr282

    authors: Parl FF,Cruz VE,Cobb CA,Bradley CA,Aleshire SL

    更新日期:1986-06-15 00:00:00

  • Replacement estrogens and risk of gynecologic cancers and breast cancer.

    abstract::The two cancers specific to women for which substantial research on their relationship to exogenous estrogens has been reported are endometrial cancer and breast cancer. With the former, the link to estrogen use is well established. The estrogen use patterns associated with increased risk of endometrial cancer are cha...

    journal_title:Cancer

    pub_type: 杂志文章,评审

    doi:10.1002/1097-0142(19901015)60:8+<1960::aid-cncr282

    authors: Hulka BS

    更新日期:1987-10-15 00:00:00

  • Combination therapy with transcatheter arterial chemoembolization and percutaneous ethanol injection compared with percutaneous ethanol injection alone for patients with small hepatocellular carcinoma: a randomized control study.

    abstract:BACKGROUND:To assess whether the effectiveness of a combination of transcatheter arterial chemoembolization (TACE) and percutaneous ethanol injection (PEI) is superior to PEI alone in the treatment of patients with small hepatocellular carcinoma (HCC), a randomized controlled study was performed. METHODS:Fifty-two pat...

    journal_title:Cancer

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1002/1097-0142(20010915)92:6<1516::aid-cncr1477

    authors: Koda M,Murawaki Y,Mitsuda A,Oyama K,Okamoto K,Idobe Y,Suou T,Kawasaki H

    更新日期:2001-09-15 00:00:00

  • Alternative bimonthly cycles of doxorubicin, cyclophosphamide, and etoposide, cisplatin with hematopoietic growth factor support in patients with carcinoma of unknown primary site.

    abstract:BACKGROUND:Because carcinomas of unknown primary origin are highly malignant tumors with a bad prognosis (median survival, 6-12 months) and no current optimal therapy, the authors designed a prospective dose-dense chemotherapy regimen with the objective of improving the results observed in patients who receive conventi...

    journal_title:Cancer

    pub_type: 临床试验,杂志文章

    doi:10.1002/cncr.10264

    authors: Culine S,Fabbro M,Ychou M,Romieu G,Cupissol D,Pinguet F

    更新日期:2002-02-01 00:00:00

  • Smoking tobacco, oral snuff, and alcohol in the etiology of squamous cell carcinoma of the head and neck: a population-based case-referent study in Sweden.

    abstract:BACKGROUND:This case-referent study was conducted to elucidate the role of selected exogenous agents in the etiology of head and neck cancer. The factors studied were tobacco smoking, alcohol intake, the use of moist oral snuff, dietary factors, occupational exposures, and oral hygiene. In this first report, the author...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/(sici)1097-0142(19980401)82:7<1367::aid-cn

    authors: Lewin F,Norell SE,Johansson H,Gustavsson P,Wennerberg J,Biörklund A,Rutqvist LE

    更新日期:1998-04-01 00:00:00

  • Fournier's gangrene complicating aggressive therapy for hematologic malignancy.

    abstract::The authors describe two cases of Fournier's gangrene complicating aggressive therapy for hematologic malignancies. Fournier's gangrene is a fulminant necrotizing fasciitis of the scrotum and penis, often with an infectious etiology. Only one prior case has been reported in a patient receiving aggressive chemotherapy ...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19860615)57:12<2291::aid-cncr282

    authors: Berg A,Armitage JO,Burns CP

    更新日期:1986-06-15 00:00:00

  • Treatment of the neck in patients with squamous cell carcinoma of the head and neck.

    abstract::A retrospective study of 702 patients with clinically positive nodes associated with squamous cell carcinoma of the oral cavity, supraglottic larynx, and hypopharynx observed from 1954 to 1968 was done. The policies of treatment for the neck were not standardized during those years. Three hundred eleven patients who s...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(197702)39:2+<868::aid-cncr282039

    authors: Jesse RH,Fletcher GH

    更新日期:1977-02-01 00:00:00