Survival and toxicity differences between 5-day and weekly cisplatin in patients with locally advanced cervical cancer.

abstract：BACKGROUND:Retrospective studies suggest that dose intensity is an important determinant of outcome in the treatment of patients with a variety of malignant diseases such as breast cancer, ovarian cancer, and lymphoma. Unfortunately, these results have not been clearly substantiated in prospective randomized trials. On...

journal_title：Cancer

authors： Long GD,Negrin RS,Hoyle CF,Kusnierz-Glaz CR,Schriber JR,Blume KG,Chao NJ

更新日期：1995-09-01 00:00:00

abstract：BACKGROUND:This review was done to assess the outcomes and patterns of recurrence in a group of patients with Stage III endometrial carcinoma that might help guide adjuvant therapy. METHODS:A retrospective review was performed of 105 patients treated from 1970-1990 at three institutions. All patients underwent abdomin...

journal_title：Cancer

authors： Greven KM,Lanciano RM,Corn B,Case D,Randall ME

更新日期：1993-06-01 00:00:00

abstract：:One hundred nine cases of ovarian tumors of low malignant potential (borderline tumors) diagnosed at Stanford University Medical Center from 1958 to 1982 were reviewed. The patients ranged in age from 10 to 79 years (mean, 40.5 years). The histologic types and corresponding stages of these neoplasms were 73 serous (St...

journal_title：Cancer

authors： Bostwick DG,Tazelaar HD,Ballon SC,Hendrickson MR,Kempson RL

更新日期：1986-11-01 00:00:00

abstract：:Canada is a westernized, market-economy nation with a publicly funded health care and cancer control system and has health indices reflective of a high-resource economy. Provision of health services is in accord with the Canada Health Act and is implemented through federal, provincial, and territorial relations wherei...

journal_title：Cancer

authors： Sutcliffe SB

更新日期：2011-05-15 00:00:00

abstract：:The altered expression of the human retinoblastoma (RB) gene has been demonstrated to play an important role in the pathogenesis of RB and other tumors. To determine whether the RB gene might be involved in the pathogenesis of human ovarian and endometrial cancer, DNA from 24 human ovarian tumors, 3 normal ovaries, 3 ...

journal_title：Cancer

authors： Sasano H,Comerford J,Silverberg SG,Garrett CT

更新日期：1990-11-15 00:00:00

abstract：BACKGROUND:Recently, peripheral lung adenocarcinomas (PLA) measuring < or = 3 cm in greatest dimension often have been diagnosed using diagnostic radiology. The objective of the current study was to determine which cytologic factors are associated with a favorable outcome and an unfavorable outcome in patients with PLA...

journal_title：Cancer

authors： Kobayashi Y,Yokose T,Kawamura K,Iwasaki S,Murata Y,Onuma S,Hasebe T,Nagai K,Sasaki S,Ochiai A

更新日期：2005-02-25 00:00:00

abstract：BACKGROUND:Traditional single-marker and multimarker molecular profiling approaches in bladder cancer do not account for major risk factors and their influence on clinical outcome. This study examined the prognostic value of molecular alterations across all disease stages after accounting for clinicopathological factor...

journal_title：Cancer

authors： Mitra AP,Castelao JE,Hawes D,Tsao-Wei DD,Jiang X,Shi SR,Datar RH,Skinner EC,Stein JP,Groshen S,Yu MC,Ross RK,Skinner DG,Cortessis VK,Cote RJ

更新日期：2013-02-15 00:00:00

abstract：BACKGROUND:The focus on noncancer causes of death in patients with breast cancer (BC) remains superficial. The objective of the current study was to assess and quantify causes of death after BC diagnosis. METHODS:In total, 754,270 women with BC in the United States who were diagnosed during 2000 through 2015 and retri...

journal_title：Cancer

authors： Afifi AM,Saad AM,Al-Husseini MJ,Elmehrath AO,Northfelt DW,Sonbol MB

更新日期：2020-04-01 00:00:00

abstract：:Cancer is among the leading causes of morbidity and mortality in the Western world. Despite recent advances, most therapeutic approaches fail to eradicate the entire neoplastic clone. The remaining cells often develop metastasis and/or recurrences and therefore may represent attractive targets of therapy. A new exciti...

journal_title：Cancer

authors： Schulenburg A,Ulrich-Pur H,Thurnher D,Erovic B,Florian S,Sperr WR,Kalhs P,Marian B,Wrba F,Zielinski CC,Valent P

更新日期：2006-11-15 00:00:00

abstract：BACKGROUND:Childhood cancer is a highly curable disease when timely diagnosis and appropriate therapy are provided. A negative impact of the coronavirus disease 2019 (COVID-19) pandemic on access to care for children with cancer is likely but has not been evaluated. METHODS:A 34-item survey focusing on barriers to ped...

journal_title：Cancer

authors： Saab R,Obeid A,Gachi F,Boudiaf H,Sargsyan L,Al-Saad K,Javakhadze T,Mehrvar A,Abbas SS,Abed Al-Agele YS,Al-Haddad S,Al Ani MH,Al-Sweedan S,Al Kofide A,Jastaniah W,Khalifa N,Bechara E,Baassiri M,Noun P,El-Houdzi J,K

更新日期：2020-09-15 00:00:00

abstract：:Fourteen examples of intravenous leiomyomatosis in the FIP files were studied. Growth beyond the uterus occurred in 10 of the 14 examples, largely in vessels in the broad ligament and in uterine and iliac veins. Metastasis to the heart occurred in 1 example. The study provides evidence that is consistent with both the...

journal_title：Cancer

authors： Norris HJ,Parmley T

更新日期：1975-12-01 00:00:00

abstract：:Light microscopic, immunocytochemical and ultrastructural studies were performed on chondrosarcomas which contained a second, noncartilagenous mesenchymal component. Attention was focused on the nonchondroid portion of each tumor in an attempt to elucidate the histogenesis of this mixed variant of chondrosarcoma. The ...

journal_title：Cancer

authors： Têtu B,Ordóñez NG,Ayala AG,Mackay B

更新日期：1986-07-15 00:00:00

abstract：BACKGROUND:The objective of this study was to assess the racial and ethnic disparities in outcomes and their association with process-of-care measures for elderly Medicare recipients with localized prostate cancer. METHODS:The Surveillance, Epidemiology, and End Results-Medicare databases for the period from 1995 to 2...

journal_title：Cancer

authors： Jayadevappa R,Chhatre S,Johnson JC,Malkowicz SB

更新日期：2011-06-01 00:00:00

abstract：:A case of carcinoid tumor of the gallbladder associated with adenocarcinoma in a 56-year-old man is reported and a review of the literature is made. The tumor was a polypoid mass with a size of 5.5 X 4.0 X 2.8 cm. Histologically, the tumor showed carcinoid and adenocarcinoma with areas of mucous change. Tumor cells co...

journal_title：Cancer

authors： Wada A,Ishiguro S,Tateishi R,Ishikawa O,Matsui Y

更新日期：1983-05-15 00:00:00

abstract：:Peripheral blood lymphocytes of patients with multiple myeloma, macroglobulinemia, and monoclonal gammopathy of uncertain significance were analyzed for B cells, and cells bearing kappa light chains and lambda light chains on their surfaces. Compared with controls, the number of B cells were decreased in all three gro...

journal_title：Cancer

authors： Dillman RO,Royston I,Meserve BL,Griffiths JC

更新日期：1981-11-15 00:00:00

abstract：:Forty-three patients with evaluable metastatic breast cancer refractory to hormonal agents and extensive combination chemotherapy including doxorubicin were treated with mitomycin, 20 mg/m2 intravenously every 6 weeks. There were five partial responses (12%) and three minor responses (7%), with a mean time to progress...

journal_title：Cancer

authors： Pasterz RB,Buzdar AU,Hortobagyi GN,Blumenschein GR

更新日期：1985-11-15 00:00:00

abstract：:Endoscopic neodymium yttrium aluminium garnet (Nd YAG) laser therapy, is a new and simple method for the palliative treatment of inoperable colorectal cancer. To date the authors have treated 70 patients and the value of this method was assessed prospectively in 14 patients. Quality of life was measured before, during...

journal_title：Cancer

authors： McGowan I,Barr H,Krasner N

更新日期：1989-03-01 00:00:00

abstract：:Identification of BCR-ABL as the defining leukemogenic event in chronic myelogenous leukemia (CML) revolutionized the treatment of the disease. Imatinib, a potent BCR-ABL inhibitor, is the standard of care for the first-line treatment of patients with chronic-phase CML because of its high long-term response rates and ...

journal_title：Cancer

authors： Kantarjian HM,Cortes J,La Rosée P,Hochhaus A

更新日期：2010-03-15 00:00:00

abstract：BACKGROUND:Most relapses of Hodgkin's disease (HD) occur within the first 2 years after diagnosis, but they may develop after a longer observation period. The aim of this study was to define the incidence, clinical course, and prognostic factors for late relapse (LR) of Hodgkin's disease. For this purpose, the authors ...

journal_title：Cancer

authors： Garcia-Carbonero R,Paz-Ares L,Arcediano A,Lahuerta J,Bartolome A,Cortes-Funes H

更新日期：1998-08-01 00:00:00

abstract：:The histologic types of lung cancer in 855 patients (747 men and 107 women) from three hospitals and one international study of insulation workers were evaluated. Of these, 196 cases had asbestos exposure. About one half of the cases were diagnosed from surgical slides and one half from autopsy slides. Squamous cell c...

journal_title：Cancer

authors： Auerbach O,Garfinkel L,Parks VR,Conston AS,Galdi VA,Joubert L

更新日期：1984-12-15 00:00:00

abstract：BACKGROUND:Local recurrence is the most frequent site of failure after resection for pancreatic cancer. Tolerance, local control, and survival obtained by the association of resection and intraoperative radiation therapy (IORT) were reported. METHODS:Between June 1985 and March 1993, 90 resections for pancreatic cance...

journal_title：Cancer

authors： Zerbi A,Fossati V,Parolini D,Carlucci M,Balzano G,Bordogna G,Staudacher C,Di Carlo V

更新日期：1994-06-15 00:00:00

abstract：:A case of a dermal nerve sheath myxoma arising in a digital nerve is reported. Similar tumors and its variants have been termed neurothekeoma, pacinian neurofibroma, bizarre cutaneous neurofibroma, and plexiform neurofibroma. The perineural sheath or the Schwann cell have been presumed to be the cell of origin by seve...

journal_title：Cancer

authors： Blumberg AK,Kay S,Adelaar RS

更新日期：1989-03-15 00:00:00

abstract：:Immunomorphologic methods were utilized to localize adenosine deaminase (ADA) in extrathymic benign lymphoid tissues and B-cell lymphomas. In reactive lymph nodes, tonsils and appendix, germinal centers displayed strong ADA-positive nuclear staining in small cleaved lymphocytes and weak nuclear and/or cytoplasmic stai...

journal_title：Cancer

authors： Chechik BE,Schrader WP,Perets A,Fernandes B

更新日期：1984-01-01 00:00:00

abstract：:Chondrosarcoma of the temporal bone is a rare lesion. Clinically it has been confused with multiple sclerosis, glomus jugulare tumors, meningioma, and chordomas. The cranial nerve palsies frequently observed with the tumors are related to the anatomic locations of the tumors. Thirteen patients with this entity are pre...

journal_title：Cancer

authors： Coltrera MD,Googe PB,Harrist TJ,Hyams VJ,Schiller AL,Goodman ML

更新日期：1986-12-15 00:00:00

abstract：BACKGROUND:The benefits of an active lifestyle after a breast cancer diagnosis are well recognized, but the majority of survivors are insufficiently active. The ACTIVATE Trial examined the efficacy of an intervention (use of the Garmin Vivofit 2 activity monitor coupled with a behavioral feedback and goal-setting sessi...

journal_title：Cancer

authors： Lynch BM,Nguyen NH,Moore MM,Reeves MM,Rosenberg DE,Boyle T,Vallance JK,Milton S,Friedenreich CM,English DR

更新日期：2019-08-15 00:00:00

abstract：BACKGROUND:p16 is strongly overexpressed in dysplastic cervical cells because of the transforming activity of the E7 oncogene of all high-risk human papillomavirus (HR-HPV) types and may be easily revealed by immunochemistry: p16 may, therefore, be considered a surrogate marker for the activated oncogene expression of ...

journal_title：Cancer

authors： Carozzi F,Cecchini S,Confortini M,Becattini V,Cariaggi MP,Pontenani G,Sani C,Ciatto S

更新日期：2006-04-25 00:00:00

abstract：BACKGROUND:To identify the factors that contribute to poorer colon carcinoma survival rates for African Americans compared with Caucasians, the authors evaluated survival differences based on the histologic grade (differentiation) of the tumor. METHODS:All 169 African Americans and 229 randomly selected non-Hispanic C...

journal_title：Cancer

authors： Alexander D,Jhala N,Chatla C,Steinhauer J,Funkhouser E,Coffey CS,Grizzle WE,Manne U

更新日期：2005-05-15 00:00:00

abstract：:Thirteen patients with regional or distant metastases from Merkel cell carcinoma were treated with combination chemotherapy. Three patients had a complete response to therapy. In two patients with nodal disease the duration of response was 10+ and 4+ years. In addition, three patients had a partial response, and six p...

journal_title：Cancer

authors： Feun LG,Savaraj N,Legha SS,Silva EG,Benjamin RS,Burgess MA

更新日期：1988-08-15 00:00:00

abstract：:Ewing's sarcoma is a small cell malignant tumor that usually arises in the medullary cavity of bone. Less frequently, it originates in soft tissue and may secondarily invade underlying bone. The origin of Ewing's sarcoma in a periosteal location without extension into either the bone or adjacent soft tissue has not be...

journal_title：Cancer

authors： Bator SM,Bauer TW,Marks KE,Norris DG

更新日期：1986-10-15 00:00:00

abstract：BACKGROUND:The ability to divide subsets of patients with glial neoplasms into prognostic groups currently is limited because only a few clinical and pathologic variables are available. The goal of this investigation was to identify biologic factors of potential prognostic value in patients with cerebral gliomas. METH...

journal_title：Cancer

authors： Ganju V,Jenkins RB,O'Fallon JR,Scheithauer BW,Ransom DT,Katzmann JA,Kimmel DW

更新日期：1994-08-01 00:00:00