Chemotherapy for metastatic Merkel cell carcinoma. Review of the M.D. Anderson Hospital's experience.

abstract：:Since November 1973, intraoperative radiotherapy has been performed on five patients with unresectable, advanced carcinoma of the bile duct at the hepatic hilus and six patients with unresectable carcinoma of the gallbladder. A treatment cone with a diameter ranging from 4--10 cm was directly applied at the lesion. A ...

journal_title：Cancer

authors： Todoroki T,Iwasaki Y,Okamura T,Nagoshi K,Asakura H,Nakano M,Inada T,Tsunemoto H,Umegaki Y,Nishimura A,Nakano M,Sato H

更新日期：1980-11-15 00:00:00

abstract：:Transgenic model systems provide tools for obtaining information that clarifies important relationships between genetic alterations and carcinogenesis. One such relationship is the induction of specific growth factor activities by dominantly acting oncogenes. Using a "transgenic organ" model referred to as mouse prost...

journal_title：Cancer

authors： Thompson TC,Truong LD,Timme TL,Kadmon D,McCune BK,Flanders KC,Scardino PT,Park SH

更新日期：1993-02-01 00:00:00

abstract：BACKGROUND:Hepatocyte growth factor receptor (c-met), autocrine motility factor receptor (AMFR), and urokinase-type plasminogen activator receptor (uPAR) are known to play important roles in tumor cell migration, invasion, and metastasis. The authors studied the relation between the expression patterns of these genes a...

journal_title：Cancer

authors： Taniguchi K,Yonemura Y,Nojima N,Hirono Y,Fushida S,Fujimura T,Miwa K,Endo Y,Yamamoto H,Watanabe H

更新日期：1998-06-01 00:00:00

abstract：BACKGROUND:hMLH1, the human MutL homologue, has been linked to microsatellite instability (MSI) in gastrointestinal tumors. However, to the authors' knowledge, the role of hMLH1, the other mismatch repair genes (MMR), and MSI in ovarian carcinoma has not been well defined. The purpose of the current study was to determ...

journal_title：Cancer

authors： Geisler JP,Goodheart MJ,Sood AK,Holmes RJ,Hatterman-Zogg MA,Buller RE

更新日期：2003-11-15 00:00:00

abstract：BACKGROUND:Radiotherapy (XRT) is effective as the primary treatment modality for laryngopharyngeal cancer; however, complications of XRT can result in significant morbidity. Few previous studies have examined the effect of continued smoking on complications of XRT. The authors of this report hypothesized that patients ...

journal_title：Cancer

authors： Zevallos JP,Mallen MJ,Lam CY,Karam-Hage M,Blalock J,Wetter DW,Garden AS,Sturgis EM,Cinciripini PM

更新日期：2009-10-01 00:00:00

abstract：:Small cell carcinoma is primarily a pulmonary neoplasm that rarely arises in extrapulmonic sites including salivary glands of the head and neck. Twelve cases of small cell carcinoma of salivary gland origin were retrieved from the Armed Forces Institute of Pathology files. Six tumors occurred in the parotid gland and ...

journal_title：Cancer

authors： Gnepp DR,Corio RL,Brannon RB

更新日期：1986-08-01 00:00:00

abstract：:A patient is presented who developed a peritoneal malignant mesothelioma in association with severe persistent and recurrent diverticulitis. The case is unusual in that a spectrum of mesothelial proliferation was documented beginning initially as benign foci of mesothelial proliferation and passing through a stage of ...

journal_title：Cancer

authors： Riddell RH,Goodman MJ,Moossa AR

更新日期：1981-07-01 00:00:00

abstract：:We have used immunohistology and radioimmunoassay procedures to study Chromogranin A (CgA) in human neuroendocrine tumor cell lines, especially small cell lung cancers (SCLC). By immunohistology, CgA could be detected in 11 of 18 classical SCLC cell lines, in a medullary thyroid carcinoma (MTC) cell line, and in only ...

journal_title：Cancer

authors： Deftos LJ,Linnoila RI,Carney DN,Burton DW,Leong SS,O'Connor DT,Murray SS,Gazdar AF

更新日期：1988-07-01 00:00:00

abstract：BACKGROUND:A study was undertaken to identify new immunogenic human leukocyte antigen (HLA)-A 2402-restricted epitopes from human papillomavirus (HPV) type 16 E7 protein for immunotherapy against cervical cancer. METHODS:Synthetic overlapping peptides were screened by measuring the frequency of CD8(+) cytotoxic T lymp...

journal_title：Cancer

authors： Jang S,Kim YT,Chung HW,Lee KR,Lim JB,Lee K

更新日期：2012-04-15 00:00:00

abstract：BACKGROUND:Cancer patients with single tumors live longer today due to earlier detection and improved treatment methods. For this reason, the authors see more patients who develop a second primary tumor. The etiology of the second tumor can be the same as the first, whether treatment-induced or unknown. The prognoses o...

journal_title：Cancer

authors： Robinson E,Segal R,Struminger L,Faraggi D,El'ad-Yarum R,Mekori T

更新日期：1999-05-01 00:00:00

abstract：:A 49-year-old white woman with refractory anemia subsequently developed acute myelomonocytic leukemia with paraproteinemia 12 months later. The paraprotein was characterized as immunoglobulin G, type kappa, and the Bence Jones protein as free kappa chains. Further studies, including electron microscopy, cytochemistry,...

journal_title：Cancer

authors： Law IP,Koch FJ,Cannon GB,Herberman RB,Oldham RK

更新日期：1976-03-01 00:00:00

abstract：BACKGROUND:This study examined the influence of prior treatment on the course of cognitive functioning in breast cancer survivors. Changes in cognitive functioning over time were compared in breast cancer survivors treated with chemotherapy plus radiotherapy, breast cancer survivors treated with radiotherapy only, and ...

journal_title：Cancer

authors： Phillips KM,Jim HS,Small BJ,Laronga C,Andrykowski MA,Jacobsen PB

更新日期：2012-04-01 00:00:00

abstract：BACKGROUND:A rare occurrence, about 1500 men in the United States develop breast carcinoma each year. Little is known about survival patterns at the population level, particularly about racial/ethnic variation. METHODS:Using data from the Surveillance, Epidemiology, and End Results Program, we examined survival rates ...

journal_title：Cancer

authors： O'Malley CD,Prehn AW,Shema SJ,Glaser SL

更新日期：2002-06-01 00:00:00

abstract：BACKGROUND:Although primary gastric lymphoma is the most common extranodal lymphoma, no specific staging system exists. METHODS:The authors reviewed 98 cases histologically classified according to the Working Formulation, including low grade B-cell lymphoma of mucosa-associated lymphoid tissue type. Survival rates wer...

journal_title：Cancer

authors： Shimodaira M,Tsukamoto Y,Niwa Y,Goto H,Hase S,Hayakawa T,Nagasaka T

更新日期：1994-06-01 00:00:00

abstract：:This review presents our experience with the use of estrogen receptors (ER) and progesterone receptors (PgR) in the prediction of response to endocrine therapy in stage IV breast cancer. Presence of ER (> 3 fmol/mg cytosol protein) significantly predicted response to the antiestrogen tamoxifen and to hypophysectomy. E...

journal_title：Cancer

authors： Manni A,Arafah B,Pearson OH

更新日期：1980-12-15 00:00:00

abstract：:The ganglioside composition of neuroblastoma samples from 53 patients was determined. Tumor sites included the adrenals (15), and the thoracic (20), abdominal (15), and pelvic (3) areas. Age of the patients at the time of surgery ranged from 1 day to over 10 years and the Stage of the tumors from A to D. Differences i...

journal_title：Cancer

authors： Schengrund CL,Repman MA,Shochat SJ

更新日期：1985-12-01 00:00:00

abstract：METHODS:The diagnostic performance of transrectal ultrasound (TRUS) gland volume and prostate specific antigen (PSA) results were evaluated in 204 men consecutively scheduled to undergo transurethral prostatic resection (TUR). RESULTS:Nonpalpable prostate cancer was detected by TRUS alone in 18% (29 of 161) and by TUR...

journal_title：Cancer

authors： Lee F,Littrup PJ,Loft-Christensen L,Kelly BS Jr,McHugh TA,Siders DB,Mitchell AE,Newby JE

更新日期：1992-07-01 00:00:00

abstract：BACKGROUND:Portal vein thrombosis (PVT) is a common complication in patients with advanced-stage hepatocellular carcinoma (HCC). The authors evaluated the impact of radiotherapy (RT) for PVT of HCC and analyzed the dose-response relation between RT and PVT. METHODS:Between March 1995 and December 2003, 59 patients dia...

journal_title：Cancer

authors： Kim DY,Park W,Lim DH,Lee JH,Yoo BC,Paik SW,Kho KC,Kim TH,Ahn YC,Huh SJ

更新日期：2005-06-01 00:00:00

abstract：:The authors performed immunohistochemical and cytogenetic studies in a 73-year old man with malignant angioendotheliomatosis. The patient was referred for evaluation of fever of unknown origin, hepatic failure, and neurologic deterioration. Examination of a muscle biopsy revealed numerous, noncohesive atypical mononuc...

journal_title：Cancer

authors： Molina A,Lombard C,Donlon T,Bangs CD,Dorfman RF

更新日期：1990-08-01 00:00:00

abstract：BACKGROUND:An Investigational New Drug (IND) treatment program allows patients access to a drug that has shown activity against a serious or life-threatening disease prior to full Food and Drug Administration (FDA) review and approval. This treatment IND program, in which patients with locally advanced or metastatic pa...

journal_title：Cancer

authors： Storniolo AM,Enas NH,Brown CA,Voi M,Rothenberg ML,Schilsky R

更新日期：1999-03-15 00:00:00

abstract：:If health professionals wish to help increase the number of older adults who get screened regularly to detect cancer at an early stage, they must first understand the barriers to screening that older people experience. This paper discusses the barriers older women face regarding mammography screening. Data from Americ...

journal_title：Cancer

authors： Rubenstein L

更新日期：1994-10-01 00:00:00

abstract：:First implemented in 1990, patient navigation interventions are emerging today as an approach to reduce cancer disparities. However, there is lack of consensus about how patient navigation is defined, what patient navigators do, and what their qualifications should be. Little is known about the efficacy and cost-effec...

journal_title：Cancer

authors： Wells KJ,Battaglia TA,Dudley DJ,Garcia R,Greene A,Calhoun E,Mandelblatt JS,Paskett ED,Raich PC,Patient Navigation Research Program.

更新日期：2008-10-15 00:00:00

abstract：:Dr. Wendell G. Scott hailed mammography as the first significant contribution to the control of breast cancer since Halsted described the radical mastectomy in 1903. Mammography as engendered new approaches and has supplied new concepts of breast cancer. Through the tenacity of a few physicians convinced something cou...

journal_title：Cancer

authors： Egan RL

更新日期：1975-11-01 00:00:00

abstract：:Thymic carcinomas are rare malignant neoplasms of the thymic epithelium that are distinguished from the malignant thymomas by the presence of cytologic atypia. Thymic carcinomas may metastasize outside of the thorax and are associated with a very poor prognosis. Complete responses of thymic carcinoma to chemotherapy a...

journal_title：Cancer

authors： Carlson RW,Dorfman RF,Sikic BI

更新日期：1990-11-15 00:00:00

abstract：:Tumor weight, carcass weight, nitrogen balance, energy balance, resting energy expenditure (REE), and activity energy expenditure (AEE) were measured in normal Fischer 344 rats, free-feeding Fischer 344 rats with methylcholanthrene-induced sarcoma (TB-FF), and similar tumor-bearing rats supported with total parenteral...

journal_title：Cancer

authors： Popp MB,Brennan MF,Morrison SD

更新日期：1982-03-15 00:00:00

abstract：:A 37-year-old woman with a giant, lymphocytic predominant thymoma involving the pleura and accompanied by a sharp peripheral blood lymphocytosis is described. Only electromicroscopic and immunohistologic studies could exclude the alternative diagnosis of mediastinal lymphoma. The tumor and peripheral blood lymphocytes...

journal_title：Cancer

authors： Shachor Y,Radnay J,Bernheim J,Rozenszajn A,Bruderman I,Klajman A,Steiner ZP

更新日期：1988-03-15 00:00:00

abstract：BACKGROUND:Patients undergoing allogeneic hematopoietic stem cell transplantation (HSCT) for chronic myeloid leukemia (CML) are increasingly likely to have received a novel tyrosine kinase inhibitor (NTKI) after failing imatinib mesylate. It is unknown whether the use of these NTKIs before HSCT increases transplant-rel...

journal_title：Cancer

authors： Jabbour E,Cortes J,Kantarjian H,Giralt S,Andersson BS,Giles F,Shpall E,Kebriaei P,Champlin R,de Lima M

更新日期：2007-07-15 00:00:00

abstract：BACKGROUND:Postgastrectomy patients undergoing chemoradiation risk chemoradiation-induced liver disease (CRILD). The objectives of this study were to investigate dosimetric implications and assess biologic susceptibility to CRILD in these patients. METHODS:Sixty-two patients with Stage IB-IV gastric/gastroesophageal a...

journal_title：Cancer

authors： Cheng JC,Liu MC,Tsai SY,Fang WT,Jer-Min Jian J,Sung JL

更新日期：2004-11-01 00:00:00

abstract：BACKGROUND:High mobility group AT-hook 1 (HMGA1) proteins are architectural transcription factors that are overexpressed by pancreatic adenocarcinomas. The authors hypothesized that tumor HMGA1 status represents a novel prognostic marker in pancreatic adenocarcinoma. They also tested the hypothesis that HMGA1 promotes ...

journal_title：Cancer

authors： Liau SS,Rocha F,Matros E,Redston M,Whang E

更新日期：2008-07-15 00:00:00

abstract：:To collect an unselected total bronchial carcinoma population as a basis for randomized therapy studies during 1971-1976, 537 patients with suspected bronchial carcinoma were investigated. Of these, 109 were found to have an adenocarcinoma in the lung. Of the 109, 10 had been initially diagnosed as not having adenocar...

journal_title：Cancer

authors： Nõu E

更新日期：1981-11-01 00:00:00