Abstract:
:Tumor weight, carcass weight, nitrogen balance, energy balance, resting energy expenditure (REE), and activity energy expenditure (AEE) were measured in normal Fischer 344 rats, free-feeding Fischer 344 rats with methylcholanthrene-induced sarcoma (TB-FF), and similar tumor-bearing rats supported with total parenteral nutrition (TB-TPN). TB-FF rats became hypophagic and demonstrated weight loss, negative nitrogen balance, and negative energy balance as the tumor enlarged. TB-FF rats had a normal FEE and AEE when tumors were small and a decreased REE and AEE when tumors were large. TB-TPN rats were maintained in positive nitrogen and energy balance. TB-TPN rats had significantly increased REE throughout the study and a decreased AEE at the end of the study. Both the host carcass and the tumor responded to increased nutritional substrate with increased growth. The decline in motor activity which characterizes cancer cachexia may not be totally dependent on malnutrition.
journal_name
Cancerjournal_title
Cancerauthors
Popp MB,Brennan MF,Morrison SDdoi
10.1002/1097-0142(19820315)49:6<1212::aid-cncr2820subject
Has Abstractpub_date
1982-03-15 00:00:00pages
1212-20issue
6eissn
0008-543Xissn
1097-0142journal_volume
49pub_type
杂志文章相关文献
CANCER文献大全abstract::Interleukin (IL)-2 therapy leads to respiratory dysfunction due to increased vascular permeability. This study examines the role of the chemoattractant, immunomodulator, and permeability-promoting agent leukotriene (LT) B4 in this setting. Sheep with chronic lung lymph fistulae were given IL-2, 10(5) U/kg as an IV bol...
journal_title:Cancer
pub_type: 杂志文章,评审
doi:10.1002/1097-0142(19901201)66:11<2357::aid-cncr282
更新日期:1990-12-01 00:00:00
abstract:BACKGROUND:The objective of this study was to compare the quality of life (QOL) of younger (< or =50 years) versus older (>50 years) women on recent completion of treatment of breast carcinoma. METHODS:Data reported herein were obtained from a baseline assessment of 304 breast carcinoma patients. These patients were e...
journal_title:Cancer
pub_type: 杂志文章,多中心研究
doi:
更新日期:1999-11-01 00:00:00
abstract:BACKGROUND:Fine-needle aspiration biopsy (FNAB) is a reliable, rapid, minimally invasive alternative to surgical biopsy when it is performed by physician specialists for the diagnosis of palpable masses. FNAB may be under-utilized in community hospitals in the U.S. because physicians without specialty training commonly...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.21976
更新日期:2006-07-15 00:00:00
abstract:BACKGROUND:Gene expression profiling (GEP) has been rapidly adopted for early breast cancer and can aid in chemotherapy decision making. Study results regarding racial disparities in testing are conflicting, and may reflect different care settings. To the authors' knowledge, data regarding the influence of provider fac...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.31222
更新日期:2018-04-15 00:00:00
abstract:BACKGROUND:The authors examined whether survivors from the Childhood Cancer Survivor Study were less likely to be in higher-skill occupations than a sibling comparison and whether certain survivors were at higher risk for lower-skill jobs. METHODS:The authors created 3 mutually exclusive occupational categories for pa...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.25867
更新日期:2011-07-01 00:00:00
abstract:BACKGROUND:Immediate or early postmastectomy breast reconstruction is performed infrequently. To the authors' knowledge, little is known regarding surgeon or patient perspectives on reconstruction treatment decisions. The purpose of the current study was to identify patient attitudes and preferences associated with bre...
journal_title:Cancer
pub_type: 杂志文章,多中心研究
doi:10.1002/cncr.21444
更新日期:2005-12-01 00:00:00
abstract::The author reviewed the question of late side effects of cancer treatment. A late side effect was defined as an unwanted and deleterious effect observed for the first time 12 months or longer after treatment. In a survey of articles published by The New England Journal of Medicine and The Lancet from 1968 to 1988, nin...
journal_title:Cancer
pub_type: 杂志文章,评审
doi:10.1002/1097-0142(19900201)65:3+<770::aid-cncr2820
更新日期:1990-02-01 00:00:00
abstract::The remaining tissue of the tracheobronchial tree from 210 men who died from lung cancer was studied to compare the histologic alterations leading to further sites of primary cancer. These men were uranium miners matched with nonminers for age and smoking habits. In the examination of a total of 28,928 cross-sections ...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(197808)42:2<483::aid-cncr2820420
更新日期:1978-08-01 00:00:00
abstract::In 95 surgically staged patients with squamous cell carcinoma of the maxillary sinus, multivariate regression analyses were employed to identify prognostic factors. Possible prognostic factors for local control were TNM stage and type of surgical procedures: T2 or T3 tumors and use of total maxillectomy showed better ...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19850101)55:1<190::aid-cncr28205
更新日期:1985-01-01 00:00:00
abstract:BACKGROUND:Patients with metastatic melanoma (MM) have very few therapy options. Based on reports of responses to paclitaxel and carboplatin (PC), 31 patients with MM were treated with PC. METHODS:Data regarding patients treated with PC were abstracted from medical records. Clinical outcomes as determined by the treat...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.21611
更新日期:2006-01-15 00:00:00
abstract:BACKGROUND:The increasing incidence of human papillomavirus (HPV)-related head and neck squamous cell carcinoma (HNSCC) highlights the need for simple and effective tools to evaluate head and neck lesions and their HPV status. The main objective of the current study was to investigate the association between abnormal c...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.28909
更新日期:2014-11-15 00:00:00
abstract::The medical records of 243 patients admitted over a five-year period with a diagnosis of carcinoma of the cervix were reviewed to determine (1) the frequency of pulmonary metastasis, (2) the relationship between the stage of the primary lesion and the incidence of pulmonary metastasis, and (3) the relationship between...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19820415)49:8<1705::aid-cncr2820
更新日期:1982-04-15 00:00:00
abstract:BACKGROUND:The difficulties adolescents and young adults (AYAs) encounter during a cancer experience may result in a reduction in or absence of empowerment. The aims of the current study were to assess levels of empowerment and associated (demographic, clinical, or psychological) factors and examine the association bet...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.30827
更新日期:2017-10-15 00:00:00
abstract::A patient is described in whom the first recurrence of a cloacogenic carcinoma of the rectum was an intrahepatic metastasis associated with an hepatic abscess caused by the anaerobic bacterium Peptococcus prevotii. Three previously reported cases of infection associated with hepatic tumor nodules have been found in wh...
journal_title:Cancer
pub_type: 杂志文章,评审
doi:10.1002/1097-0142(197802)41:2<682::aid-cncr2820410
更新日期:1978-02-01 00:00:00
abstract:BACKGROUND:The primary objective of this study was to clarify the significance of p21WAF1/CIP1(p21) gene expression in the tumorgenicity of hepatitis B virus (HBV) and hepatitis C virus (HCV) infected human hepatocelluar carcinoma (HCC). METHODS:The authors performed Northern blot hybridization to compare the p21 mess...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(20010601)91:11<2096::aid-cncr123
更新日期:2001-06-01 00:00:00
abstract:BACKGROUND:Disparities in treatment and mortality for colorectal cancer (CRC) may reflect differences in access to specialized care or other characteristics of the area where an individual lives. METHODS:Surveillance, Epidemiology and End Results Program-Medicare data for seniors diagnosed with CRC were linked to area...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.26034
更新日期:2011-09-15 00:00:00
abstract::The geographic and demographic data obtained during the Third National Cancer Survey have provided a perspective on etiologic factors and incidence trends for cancers of low frequency. The incidence of cancer of the lip, oral cavity and skin from this survey was compared to similar studies in 1947 and intra-regional p...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(197707)40:1<343::aid-cncr2820400
更新日期:1977-07-01 00:00:00
abstract:BACKGROUND:In this report, the authors describe their collective experience with melphalan-based autotransplants since the inception of their program at the University of Arkansas for Medical Sciences in 1989. METHODS:The authors evaluated the clinical outcomes of 3077 successive patients with multiple myeloma (MM) wh...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.23327
更新日期:2008-04-15 00:00:00
abstract:BACKGROUND:Patients with renal cell carcinoma brain metastases (RCCBM) are frequently excluded from trials and to the authors' knowledge no guidelines currently exist regarding central nervous system (CNS) surveillance or treatment. The objective of the current study was to assist in the creation of treatment guideline...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.23769
更新日期:2008-10-01 00:00:00
abstract::The authors describe their experience with total body irradiation (TBI) with 8 MeV-x rays in the treatment of disseminated tumors. With a dose of 125 rad, given three times with 2-week intervals, some objective remissions (6/26) were obtained, especially in patients with lymphomas. For solid tumors only subjective imp...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(197704)39:4<1435::aid-cncr282039
更新日期:1977-04-01 00:00:00
abstract::Sixteen patients with metastatic neuroendocrine tumors and the malignant carcinoid syndrome were treated with cyproheptadine (Periactin, Merck, Sharp & Dohme, West Point, PA) at maximum tolerable doses that ranged from 12 to 48 mg daily. Usual side effects were mild sedation and dry mouth, but three patients found it ...
journal_title:Cancer
pub_type: 临床试验,杂志文章
doi:10.1002/1097-0142(19910101)67:1<33::aid-cncr282067
更新日期:1991-01-01 00:00:00
abstract::The effect of multimodal immunotherapy was studied in rats bearing primary gastrointestinal tumors induced by 1,2-dimethylhydrazine dihydrochloride. Multimodal immune manipulation consisted of combinations of splenectomy, C. parvum, unblocking serum, unblocked lymphoid cells, and levamisole. Such immunologic intervent...
journal_title:Cancer
pub_type: 杂志文章,评审
doi:10.1002/1097-0142(197811)42:5<2079::aid-cncr282042
更新日期:1978-11-01 00:00:00
abstract::This study investigated whether an endoscopic surveillance program for patients with "benign" gastric ulcers and gastric cancer leads to early detection of neoplasms and improves survival. The clinical course of all patients diagnosed between 1977 and 1986 as having either gastric ulcers or gastric cancer was followed...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19920115)69:2<301::aid-cncr28206
更新日期:1992-01-15 00:00:00
abstract:BACKGROUND:This survey documents the strategies used by pain control physicians in the selection of opioid drugs and routes of administration in the management of inpatients referred to a cancer pain service. METHODS:The following approaches were prospectively evaluated during the treatment of 100 consecutive inpatien...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19951001)76:7<1283::aid-cncr2820
更新日期:1995-10-01 00:00:00
abstract:BACKGROUND:Epithelioid hemangioendothelioma (EHE) is a rare neoplasm of vascular origin that occurs in the liver and other organs; its etiology is unknown. METHODS:The authors analyzed the clinicopathologic and immunohistochemical features of 137 patients with EHE of the liver in an attempt to identify features that m...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/(sici)1097-0142(19990201)85:3<562::aid-cnc
更新日期:1999-02-01 00:00:00
abstract::During the past decade, one of the major changes in the field of oncology has been in the surgical approach to primary and secondary cancer of the liver. As a result of data and experience gained in liver transplantation programs and with the application of vascular surgical principles, resectability rates have been i...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19810501)47:9<2162::aid-cncr2820
更新日期:1981-05-01 00:00:00
abstract::In 25 patients under treatment or during follow-up for acute lymphoblastic leukemia magnetic resonance imaging (MRI) of both knees was compared to history and physical examination to detect osteonecrosis. Results of MRI were classified as: O, normal bone marrow (BM); 1, diffuse decrease in signal intensity; 2, circums...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19871215)60:12<2994::aid-cncr282
更新日期:1987-12-15 00:00:00
abstract::Fifty-four patients with advanced squamous, large-cell or adeno-carcinoma of the lung were treated with a three drug regimen of high-dose cisplatin, vindesine and a four-day bleomycin infusion (CVB). All patients had measurable disease; none had previously received chemotherapy. Of 52 patients evaluable for response, ...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19830315)51:6<1050::aid-cncr2820
更新日期:1983-03-15 00:00:00
abstract::In a retrospective review (1950-1975) of the Mayo Clinic experience with seminomas (483 cases), twelve patients (2.5%) were found to have a retroperitoneal seminoma without evidence of testicular involvement. The mean age was 47 years (range, 31-67). Eleven patients were treated by radiation alone, with doses ranging ...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19820501)49:9<1934::aid-cncr2820
更新日期:1982-05-01 00:00:00
abstract:BACKGROUND:The authors hypothesized that comprehensive genomic profiling of advanced-stage cutaneous squamous cell carcinoma (cSCC) could identify genomic-derived drug targets of therapy for patients with conventional therapy-resistant disease. METHODS:Comprehensive genomic profiling of 315 cancer genes was applied to...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.29738
更新日期:2016-01-15 00:00:00