Age-related differences in the quality of life of breast carcinoma patients after treatment.

abstract：:The field of chemical carcinogenesis is reviewed, with emphasis on three aspects: 1) environmental chemicals are a major cause of human cancer; 2) most chemical carcinogens require metabolic activation by mixed-function oxidases to electrophilic metabolites that form strong covalent chemical bonds with cellular macrom...

journal_title：Cancer

authors： Heidelberger C

更新日期：1977-07-01 00:00:00

abstract：:The results of assay for estrogen receptor (ER) in the tumor cytosol and thymidine labeling indices (TLI) of 63 primary invasive carcinomas of the breast were analyzed. The ER assay was performed by using dextran-charcoal to adsorb unbound tritiated estradiol-17beta (E2) in cytosol. The TLI was measured as the number ...

journal_title：Cancer

authors： Meyer JS,Rao BR,Stevens SC,White WL

更新日期：1977-11-01 00:00:00

abstract：BACKGROUND:In preclinical Ewing sarcoma (ES) models, poly(adenosine diphosphate ribose) polymerase (PARP) inhibitors were identified as a potential therapeutic strategy with synergy in combination with cytotoxic agents. This study evaluated the safety and dosing of the PARP1/2 inhibitor niraparib (NIR) with temozolomid...

journal_title：Cancer

authors： Chugh R,Ballman KV,Helman LJ,Patel S,Whelan JS,Widemann B,Lu Y,Hawkins DS,Mascarenhas L,Glod JW,Ji J,Zhang Y,Reinke D,Strauss SJ

更新日期：2020-12-08 00:00:00

abstract：BACKGROUND:Two similarly effective treatment options exist for managing clinical low volume Stage II nonseminomatous germ cell testis tumors (NSGCT). Primary retroperitoneal lymph node dissection (RPLND) (with immediate adjuvant chemotherapy or chemotherapy at relapse) and primary chemotherapy have resulted in similar ...

journal_title：Cancer

authors： Baniel J,Roth BJ,Foster RS,Donohue JP

更新日期：1995-06-15 00:00:00

abstract：:Twenty-four patients with various solid tumors including metastatic liver cancer and cancer of the lung, gallbladder, and pancreas were treated with a lipophilic macromolecular drug, copoly(styrene-maleic acid) conjugated neocarzinostatin (SMANCS). The drug was dissolved in a lipid contrast medium Lipiodol and adminis...

journal_title：Cancer

authors： Konno T,Maeda H,Iwai K,Maki S,Tashiro S,Uchida M,Miyauchi Y

更新日期：1984-12-01 00:00:00

abstract：:Fifty patients with non resectable and/or inoperable bronchogenic carcinoma were entered into a feasibility study of cisplatin (CDDP) given in continuous infusion with concurrent radiation therapy. The radiation therapy regimen consisted of 2 Gy given 5 days a week in the first 3 and last 2 weeks of a 7-week split cou...

journal_title：Cancer

authors： Bedini AV,Tavecchio L,Milani F,Gramaglia A,Spreafico C,Marchianò A,Ravasi G

更新日期：1991-01-15 00:00:00

abstract：:Many cancer patients have elevated serum protein and sialic acid (N-acetyl neuraminic acid, NANA) levels. Serial determinations were performed, using serum treated with perchloric acid from 34 patients with widespread metastatic disease. Six of six patients who underwent debulking surgery had a drop in their serum NAN...

journal_title：Cancer

authors： Harvey HA,Lipton A,White D,Davidson E

更新日期：1981-01-15 00:00:00

abstract：:109 cases of breast cancer were treated by tumorectomy and radiotherapy or radiotherapy alone. Almost 30% with small tumors (T1, T2) were considered inoperable for medical reasons and 70% refused mastectomy. Over the past five years the number of patients refusing mastectomy has definitely increased. 59 cases of surgi...

journal_title：Cancer

authors： Alpert S,Ghossein NA,Stacey P,Migliorelli FA,Efron G,Krishnaswamy V

更新日期：1978-10-01 00:00:00

abstract：BACKGROUND:The Early Lung Cancer Action Project (ELCAP) is designed to evaluate baseline and annual repeat screening by low radiation dose computed tomography (low-dose CT) in persons at high-risk for lung cancer. The authors report on the baseline screening experience. For full evaluation of screening, they await the ...

journal_title：Cancer

authors： Henschke CI

更新日期：2000-12-01 00:00:00

abstract：BACKGROUND:Based on prior experience with dacarbazine (DTIC) and an outpatient interleukin-2 (IL-2) regimen, the current study was conducted to improve the antitumor efficacy and assess the immunologic interactions between chemotherapy and IL-2. METHODS:Thirty-two patients were registered onto a treatment program, whi...

journal_title：Cancer

authors： Flaherty LE,Robinson W,Redman BG,Gonzalez R,Martino S,Kraut M,Valdivieso M,Rudolph AR

更新日期：1993-06-01 00:00:00

abstract：BACKGROUND:PC-SPES is an herbal supplement whose mechanisms of action are poorly understood, but may be estrogenic. The objective of the current report is to describe the effects of discontinuing PC-SPES treatment in four patients with androgen-independent prostate carcinoma. METHODS:Patient charts were retrospectivel...

journal_title：Cancer

authors： Oh WK,George DJ,Kantoff PW

更新日期：2002-02-01 00:00:00

abstract：BACKGROUND:The mortality of patients with colorectal carcinoma depends mainly upon subsequent liver metastasis even after curative operation. However, it is very difficult to predict the incidence of liver metastasis by analyzing conventional tumor markers or pathologic findings. In the current study, the authors exami...

journal_title：Cancer

authors： Kato M,Ito Y,Kobayashi S,Isono K

更新日期：1996-04-15 00:00:00

abstract：:The author reviewed the question of late side effects of cancer treatment. A late side effect was defined as an unwanted and deleterious effect observed for the first time 12 months or longer after treatment. In a survey of articles published by The New England Journal of Medicine and The Lancet from 1968 to 1988, nin...

journal_title：Cancer

authors： Boivin JF

更新日期：1990-02-01 00:00:00

abstract：BACKGROUND:Tumors consisting of a combination of malignant melanoma and carcinoma are very rare. The authors report two such cases occurring as primary breast tumors. METHODS:The breast tumors were analyzed by histologic, immunohistochemical, and ultrastructural techniques. RESULTS:Histologically, the tumors were com...

journal_title：Cancer

authors： Padmore RF,Lara JF,Ackerman DJ,Gales T,Sigurdson ER,Ehya H,Cooper HS,Patchefsky AS

更新日期：1996-12-15 00:00:00

abstract：:Radiation therapy alone, surgery alone, or the combination of these two modalities, remain the accepted treatments in the management of epidermoid carcinomas of the mucosa of the head and neck. These modalities of therapy produce comparable results; but, radiotherapy alone has the advantage that it can conserve anatom...

journal_title：Cancer

authors： Marcial VA,Pajak TF

更新日期：1985-05-01 00:00:00

abstract：BACKGROUND:Systemic anticancer therapies can produce acute and chronic organ damage, but the eye is usually considered a protected site. Nonetheless, the oculo-visual system has a potentially high degree of sensitivity to toxic substances. Ocular toxicity induced by cancer chemotherapy includes a broad spectrum of diso...

journal_title：Cancer

authors： al-Tweigeri T,Nabholtz JM,Mackey JR

更新日期：1996-10-01 00:00:00

abstract：BACKGROUND:The objective of this study was to evaluate the long-term survival and late toxicities of concurrent-adjuvant chemotherapy in patients with stage III through IVB nasopharyngeal carcinoma (NPC) from endemic regions of China. METHODS:Patients with stage III to IVB NPC were assigned randomly to receive radioth...

journal_title：Cancer

authors： Chen Y,Sun Y,Liang SB,Zong JF,Li WF,Chen M,Chen L,Mao YP,Tang LL,Guo Y,Lin AH,Liu MZ,Ma J

更新日期：2013-06-15 00:00:00

abstract：:Two patients diagnosed as having acute promyelocytic leukemia (APL) and disseminated intravascular coagulation (DIC) were closely followed from the day of admission until completion of the first course of chemotherapy with serial coagulation studies including plasma levels of functional antithrombin III activity (AT I...

journal_title：Cancer

authors： Sandler RM,Liebman HA,Patch MJ,Teitelbaum A,Levine AM,Feinstein DI

更新日期：1983-02-15 00:00:00

abstract：:Five cases of squamous cell carcinoma of the cervix associated with widespread squamous cell carcinoma in situ of the endometrial surface are reported. In one case, carcinoma in situ was also found in one fallopian tube in continuity with the cervicoendometrial lesion. A survey of the literature reveals only 20 cases ...

journal_title：Cancer

authors： Kanbour AI,Stock RJ

更新日期：1978-08-01 00:00:00

abstract：:A case of malignant eccrine poroma with lymph node metastases is described. The patient had a nodular growth of the right thigh 2 years before its first excision. Local recurrence in the scar occurred in 6 months, and by 8 months a right groin lymph node was involved. Subsequent skin nodules of the right thigh occurre...

journal_title：Cancer

authors： Bottles K,Sagebiel RW,McNutt NS,Jensen B,Deveney K

更新日期：1984-04-01 00:00:00

abstract：:Peripheral B- and T-lymphocyte counts were studied in 50 patients before they received any therapy for their conditions: 16 had carcinoma of the breast; 8 soft tissue sarcoma; and 26, benign disease. Among 11 males, the six patients with advanced soft tissue sarcoma had significantly lower percentages of T lymphocytes...

journal_title：Cancer

authors： Lee YT,Marshall GJ,Weiner J,Bateman JR

更新日期：1977-08-01 00:00:00

abstract：BACKGROUND:Patients with chronic lymphocytic leukemia (CLL) that transforms to Richter syndrome (RS) frequently show atypical lymphocytes in bone marrow; however, a diagnosis of RS requires confirmation of the presence of sheets of large cells in bone marrow or lymph nodes. METHODS:In this study, the authors evaluated...

journal_title：Cancer

authors： Ma Y,Mansour A,Bekele BN,Zhou X,Keating MJ,O'Brien S,Giles FJ,Albitar M

更新日期：2004-05-15 00:00:00

abstract：:Both cytogenetic analysis and flow cytometry (FCM) have prognostic efficacy in the analysis of transitional cell carcinoma (TCC) of urinary bladder. To correlate results of the two methods, we studied a unique group of patients whose tumors had undergone prospective conventional cytogenetic analysis. Paraffin blocks o...

journal_title：Cancer

authors： Coon JS,Schwartz D,Summers JL,Miller AW 3rd,Weinstein RS

更新日期：1986-04-15 00:00:00

abstract：BACKGROUND:The echinoderm microtubule-associated protein-like 4-anaplastic lymphoma kinase (EML4-ALK) fusion gene resulting from the chromosome inversion inv(2)(p21;p23) recently was identified in nonsmall cell lung cancer (NSCLC). The authors of this study investigated the frequency, genetic and clinicopathologic prof...

journal_title：Cancer

authors： Wong DW,Leung EL,So KK,Tam IY,Sihoe AD,Cheng LC,Ho KK,Au JS,Chung LP,Pik Wong M,University of Hong Kong Lung Cancer Study Group.

更新日期：2009-04-15 00:00:00

abstract：:In a clinical trial, 42 patients with abdominal Burkitt's lymphoma (BL) were treated with a combination regimen, code-named CVA, consisting of cyclophosphamide (CTX), vincristine, and cystosine arabinoside. In addition, intrathecal methotrexate (i.t. MTX) was administered as prophylaxis against subsequent central nerv...

journal_title：Cancer

authors： Nkrumah FK,Perkins IV,Biggar RJ

更新日期：1977-10-01 00:00:00

abstract：:Bacteria-antibody complexes were used to study capping of receptors for the activated third component of complement on peripheral blood lymphocytes. The impairment of C3d receptor capping improves in patients with chronic lymphocytic leukemia responding to therapy, but this does not necessarily correspond to the fall ...

journal_title：Cancer

authors： Hendrick AM,Gormus BJ,Leech SH

更新日期：1985-10-01 00:00:00

abstract：:The current results of trials testing combined surgery and chemotherapy in patients with breast cancer is reviewed. Information concerning eight trials utilizing nine single-agent regimens was obtained. The results at this time are conflicting. There appear to be differences among the regimens utilized in the various ...

journal_title：Cancer

authors： Tormey DC

更新日期：1975-09-01 00:00:00

abstract：:Serum complements, C3, C4, and C3 proactivator (C3PA), were evaluated prospectively for their diagnostic power in detecting hepatocellular carcinoma (HCC) in patients with liver cirrhosis (LC). Sixty-three LC patients, including 36 LC with HCC patients, were recruited for this study during the period from March to Nov...

journal_title：Cancer

authors： Chang WY,Chuang WL

更新日期：1988-07-15 00:00:00

abstract：:Retrospective immunocytochemical study of prolactin, growth hormone, ACTH, TSH and gonadotropins was performed on 150 pituitary adenomas from 142 patients and the results were correlated with clinical manifestations. There were 60 prolactin-positive tumors, 13 growth hormone-positive tumors, nine ACTH-positive tumors ...

journal_title：Cancer

authors： Mukai K

更新日期：1983-08-15 00:00:00

abstract：BACKGROUND:Primary myelofibrosis (PMF) and overlap myelodysplastic/myeloproliferative neoplasms (MDS/MPN) are clonal hematopoietic disorders that share similar clinical features and molecular abnormalities, such as the Janus kinase 2 (JAK2) valine to phenylalanine mutation at codon 617 (V617F) and the tet methylcytosin...

journal_title：Cancer

authors： Bejanyan N,Tiu RV,Raza A,Jankowska A,Kalaycio M,Advani A,Chan J,Saunthararajah Y,Mooney L,Maciejewski JP,Sekeres MA

更新日期：2012-08-15 00:00:00