Selective targeting of anti-cancer drug and simultaneous image enhancement in solid tumors by arterially administered lipid contrast medium.

abstract：:Amyloid as defined by positive Congo red green birefringence and STB red birefringence was observed in the stroma of a tubular carcinoma of minor salivary gland origin. The amyloid exhibited additional histochemical characteristics of immunamyloid, viz., positive DMAB-nitrate and DC-reactions and spontaneous autofluor...

journal_title：Cancer

authors： David R,Buchner A

更新日期：1978-05-01 00:00:00

abstract：:Doubling times were estimated for 15 breast carcinomas in 13 patients, and were found to be between 42 and 397 days with the average at 211 days. The mean lead time at mean growth rate from the average size of 44 preclinical to the average size of 118 clinical tumors was estimated to be 3 years. This period may be con...

journal_title：Cancer

authors： Lundgren B

更新日期：1977-10-01 00:00:00

abstract：BACKGROUND:Hemangiopericytomas and malignant solitary fibrous tumors (HPC/SFT) are rare, closely related sarcomas with unpredictable behavior that respond infrequently to chemotherapy. An optimal systemic treatment strategy for advanced HPC/SFT has not yet been identified. METHODS:We retrospectively analyzed the recor...

journal_title：Cancer

authors： Park MS,Patel SR,Ludwig JA,Trent JC,Conrad CA,Lazar AJ,Wang WL,Boonsirikamchai P,Choi H,Wang X,Benjamin RS,Araujo DM

更新日期：2011-11-01 00:00:00

abstract：BACKGROUND:: Histologic parameters of melanoma deposits in sentinel lymph nodes (SLNs) have been shown to be predictive of clinical outcome and the presence or absence of tumor in non-SLNs, but assessment of these parameters is prone to interobserver variation. METHODS:: Histologic sections of 44 SLNs containing metas...

journal_title：Cancer

authors： Murali R,Cochran AJ,Cook MG,Hillman JD,Karim RZ,Moncrieff M,Starz H,Thompson JF,Scolyer RA

更新日期：2009-11-01 00:00:00

abstract：:A novel sequential administration schedule of PALA (N-phosphonoacetyl-L-aspartate) and thymidine to enhance the cytotoxic effect of 5-fluorouracil (5FU) was tested in 36 patients with advanced gastric cancer and 21 patients with advanced poorly differentiated (anaplastic) colorectal cancer. The potency of 5FU was dram...

journal_title：Cancer

authors： Windschitl HE,O'Connell MJ,Wieand HS,Krook JE,Rubin J,Moertel CG,Kugler JW,Pfeifle DM,Goldberg RM,Laurie JA

更新日期：1990-09-01 00:00:00

abstract：BACKGROUND:Accelerated radiotherapy (RT) represents a promising method with which to improve the treatment outcome in patients with head and neck carcinoma. However, its applicability to elderly patients has not been well established. This study assessed treatment toxicities, patient compliance, and oncologic results i...

journal_title：Cancer

authors： Allal AS,Maire D,Becker M,Dulguerov P

更新日期：2000-02-01 00:00:00

abstract：BACKGROUND:Strong correlations have been reported between expression of urokinase-type plasminogen activator (uPA) and poor prognosis in several human carcinomas. The clinical significance of secreted levels of uPA, its receptor (uPAR), and its inhibitors (PAI-1 and PAI-2) in the ascites of patients with epithelial ova...

journal_title：Cancer

authors： Chambers SK,Gertz RE Jr,Ivins CM,Kacinski BM

更新日期：1995-04-01 00:00:00

abstract：BACKGROUND:Hormone replacement therapy (HRT) has proven and presumable benefits for women desiring postmenopausal health preservation. Among HRT-associated risks, the fear of breast carcinoma intimidates women and physicians contemplating hormonal treatment and limits long-term compliance. Identifying effective alterna...

journal_title：Cancer

authors： Diamanti-Kandarakis E,Sykiotis GP,Papavassiliou AG

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND:The development of new chelating agents and radiolabeling protocols is essential to progress in radioimmunotherapy with antibody-chelate conjugates. METHODS:Immunoconjugates of four polyazamacrocycles with N-bonded acetate groups were prepared by conjugation via 2-iminothiolane to Lym-1, a murine antilympho...

journal_title：Cancer

authors： Kukis DL,Diril H,Greiner DP,DeNardo SJ,DeNardo GL,Salako QA,Meares CF

更新日期：1994-02-01 00:00:00

abstract：BACKGROUND:Strumal carcinoids (SC) are ovarian tumors containing thyroid parenchyma admixed with carcinoid elements. Microscopically, the carcinoid component of SC usually presents a ribbon or trabecular pattern similar to the pattern exhibited by hindgut carcinoids. The authors designed an immunohistochemical study to...

journal_title：Cancer

authors： Sidhu J,Sánchez RL

更新日期：1993-09-01 00:00:00

abstract：BACKGROUND:Effective multidisciplinary rehabilitation programs supporting the return to work have become increasingly relevant for cancer survivors. In Germany, inpatient work-related medical rehabilitation programs consider treatment modules of work-related diagnostics, work-related functional capacity training, psych...

journal_title：Cancer

authors： Fauser D,Wienert J,Beinert T,Schmielau J,Biester I,Krüger HU,Presl A,Bethge M

更新日期：2019-08-01 00:00:00

abstract：BACKGROUND:Modern cancer treatments can cure or prolong patients' lives. However, the associated physical and psychosocial problems can detrimentally affect patients' compliance with treatment and, ultimately, their outcomes. Therefore, oncologists need to recognize the problems experienced by their patients and, when ...

journal_title：Cancer

authors： Newell S,Sanson-Fisher RW,Girgis A,Bonaventura A

更新日期：1998-10-15 00:00:00

abstract：BACKGROUND:The authors reviewed changes in the initial clinical presentation, management techniques, and patterns of disease recurrence over time (1981-1996) in patients with breast carcinoma treated with breast-conserving therapy (BCT) at a single institution. The goals of the current study were to determine the frequ...

journal_title：Cancer

authors： Pass H,Vicini FA,Kestin LL,Goldstein NS,Decker D,Pettinga J,Ingold J,Benitez P,Neumann K,Rebner M,Dekhne N,Martinez A

更新日期：2004-08-15 00:00:00

abstract：BACKGROUND:Age-related disparities in colon cancer treatment exist, with older patients being less likely to receive recommended therapy. However, to the authors' knowledge, few studies to date have focused on receipt of surgery. The objective of the current study was to describe patterns of surgery in patients aged ≥ ...

journal_title：Cancer

authors： Neuman HB,O'Connor ES,Weiss J,Loconte NK,Greenblatt DY,Greenberg CC,Smith MA

更新日期：2013-02-01 00:00:00

abstract：:Despite proven benefits of neoadjuvant chemotherapy in patients with locally advanced, invasive breast cancer, no regimen is recommended as the treatment of choice. Neoadjuvant chemotherapy regimens encompass single-agent and combination therapy and sequential treatment. For this report, the author reviewed the litera...

journal_title：Cancer

authors： Buzdar AU

更新日期：2007-12-01 00:00:00

abstract：BACKGROUND:The authors suggested that the loss of collagen IV and laminin-containing basement membrane and the loss of Disabled-2 (Dab2) expression were two critical events associated with morphologic dysplastic changes of the ovarian surface epithelium as a step in tumorigenicity. Both the basement membrane and Dab2, ...

journal_title：Cancer

authors： Roland IH,Yang WL,Yang DH,Daly MB,Ozols RF,Hamilton TC,Lynch HT,Godwin AK,Xu XX

更新日期：2003-12-15 00:00:00

abstract：BACKGROUND:Louisiana is one of the few Southern states that enacted the Medicaid expansion of the Patient Protection and Affordable Care Act (ACA). To the authors' knowledge, the issue of how this has affected the breast cancer landscape in Louisiana is unknown. The authors have postulated that ACA expansion had a posi...

journal_title：Cancer

authors： Chu QD,Li T,Hsieh MC,Yi Y,Gibbs JF,Lyons JM 3rd,Wu XC

更新日期：2020-11-03 00:00:00

abstract：:From a total of 874 patients with small cell lung cancer (SCC), a series of 104 patients were reviewed to determine if bone marrow relapses are detectable by routine clinical investigations. Autopsy, including microscopical bone marrow examination, was performed in all the 104 patients and bone metastases were disclos...

journal_title：Cancer

authors： Kristjansen PE,Osterlind K,Hansen M

更新日期：1986-12-01 00:00:00

abstract：BACKGROUND:In a previous study of gene array data, the authors identified survivin as a candidate marker of aggressiveness in clear cell renal cell carcinoma (ccRCC). What remained in question was whether survivin expression at the protein level is an independent predictor of disease progression and cancer-specific sur...

journal_title：Cancer

authors： Parker AS,Kosari F,Lohse CM,Houston Thompson R,Kwon ED,Murphy L,Riehle DL,Blute ML,Leibovich BC,Vasmatzis G,Cheville JC

更新日期：2006-07-01 00:00:00

abstract：BACKGROUND:Studies evaluating the efficacy of routine follow-up testing in detecting disease recurrence in treated lung carcinoma patients are lacking. METHODS:To investigate this subject, the authors studied 115 patients who had previously been entered on North Central Cancer Treatment Group (NCCTG) small cell lung c...

journal_title：Cancer

authors： Perez EA,Loprinzi CL,Sloan JA,Owens DT,Novotny PJ,Bonner JA

更新日期：1997-08-15 00:00:00

abstract：:Canada is a westernized, market-economy nation with a publicly funded health care and cancer control system and has health indices reflective of a high-resource economy. Provision of health services is in accord with the Canada Health Act and is implemented through federal, provincial, and territorial relations wherei...

journal_title：Cancer

authors： Sutcliffe SB

更新日期：2011-05-15 00:00:00

abstract：:The histology of 36 benign and four proliferative Brenner tumors is reviewed, and the ultrastructural features of benign Brenner tumors are described. Evidence is presented for the origin of these tumors from celomic inclusion cysts through transitional metaplasia of the cyst lining and progressive growth of branching...

journal_title：Cancer

authors： Shevchuk MM,Fenoglio CM,Richart RM

更新日期：1980-12-15 00:00:00

abstract：BACKGROUND:Previous studies have suggested an excess cancer risk in patients with carcinoid tumors. This association was reexamined using truly population-based data. METHODS:By means of data from the Danish Cancer Registry all carcinoid tumors diagnosed in Denmark between 1978 and 1989 were identified. All patients w...

journal_title：Cancer

authors： Westergaard T,Frisch M,Melbye M

更新日期：1995-07-01 00:00:00

abstract：:The effectiveness of combined modality therapy was studied in 29 patients with metastatic extradural spinal tumor who had had a previous diagnosis of malignancy. Dexamethasone was begun upon suspicion of the diagnosis in a dose of 40 mg daily. Following emergency myelography, in all patients without rapid progression,...

journal_title：Cancer

authors： Marshall LF,Langfitt TW

更新日期：1977-11-01 00:00:00

abstract：BACKGROUND:Although there have been a few reports dealing with the sarcomatous changes of intrahepatic cholangiocarcinoma, its clinicopathologic features as well as immunohistochemical nature remain obscure. METHODS:Among 155 cases of intrahepatic cholangiocarcinoma, 7 cases of sarcomatous cholangiocarcinoma were chos...

journal_title：Cancer

authors： Nakajima T,Tajima Y,Sugano I,Nagao K,Kondo Y,Wada K

更新日期：1993-09-15 00:00:00

abstract：:Sixty-two patients with acute leukemia who remained in continuous complete remission for 8 to 45 months received three courses of intensified therapy with new chemotherapeutic agents, after which they received no further chemotherapy. Immunotherapy with BCG was then administered to 55 of these patients. They have been...

journal_title：Cancer

authors： Bodey GP,Freireich EJ,McCredie KB,Smith TL,Gehan EA,Gutterman JU,Hersh EM

更新日期：1981-04-15 00:00:00

abstract：BACKGROUND:Stomach cancer was a leading cause of cancer-related deaths early in the 20th century and has steadily declined over the last century in the United States. Although incidence and death rates are now low, stomach cancer remains an important cause of morbidity and mortality in black, Asian and Pacific Islander...

journal_title：Cancer

authors： Jim MA,Pinheiro PS,Carreira H,Espey DK,Wiggins CL,Weir HK

更新日期：2017-12-15 00:00:00

abstract：:Chlorozotocin was administered by rapid intravenous infusion to 35 patients with advanced cancer on either single-day of five-consecutive-day schedules. Total doses per course ranged from 12.5 to 200 mg/m2. On either administration schedule, dose limiting toxicities were thrombocytopenia and leukopenia at total doses ...

journal_title：Cancer

authors： Kovach JS,Moertel CG,Schutt AJ,Frytak S,O'Connell MJ,Rubin J,Ingle JN

更新日期：1979-06-01 00:00:00

abstract：:Forty-four cases of skin and soft tissue angiosarcoma seen at M. D. Anderson Hospital before 1976 were reviewed. The cases fell into six different clinical groups: scalp-face, 17 cases; postmastectomy, 14 cases; postradiation, 5 cases; leg with vascular stasis, 2 cases; breast, 2 cases; and miscellaneous, 4 cases. In ...

journal_title：Cancer

authors： Maddox JC,Evans HL

更新日期：1981-10-15 00:00:00

abstract：:Between January 1988 and June 1990, seven previously untreated patients with histologically confirmed and clinically staged IIIa invasive thymoma (IT) were enrolled in a prospective, single treatment arm study of neoadjuvant chemotherapy (NC) followed by surgery and postoperative radiation therapy (4600 to 6000 cGy). ...

journal_title：Cancer

authors： Macchiarini P,Chella A,Ducci F,Rossi B,Testi C,Bevilacqua G,Angeletti CA

更新日期：1991-08-15 00:00:00