Amyloid stroma in a tubular carcinoma of palatal salivary gland: a histochemical and ultrastructural study.

Abstract:

:Amyloid as defined by positive Congo red green birefringence and STB red birefringence was observed in the stroma of a tubular carcinoma of minor salivary gland origin. The amyloid exhibited additional histochemical characteristics of immunamyloid, viz., positive DMAB-nitrate and DC-reactions and spontaneous autofluorescence. Electron microscopic studies of the epithelial tumor cells displayed large amounts of cytoplasmic microfilaments similar to those present in the extracellular amyloid masses. It is suggested that the amyloid is derived from spontaneous assembly or polymerization of cytoplasmic microfibrils of the dying tumor cells as has been proposed for the amyloid associated with the calcifying epithelial odontogenic tumor (CEOT).

journal_name

Cancer

journal_title

Cancer

authors

David R,Buchner A

doi

10.1002/1097-0142(197805)41:5<1836::aid-cncr282041

subject

Has Abstract

pub_date

1978-05-01 00:00:00

pages

1836-44

issue

5

eissn

0008-543X

issn

1097-0142

journal_volume

41

pub_type

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