Familial ovarian cancer. A report of 658 families from the Gilda Radner Familial Ovarian Cancer Registry 1981-1991.

abstract：BACKGROUND:Humoral hypercalcemia rarely is associated with colorectal carcinoma; to the authors' knowledge only nine cases have been reported to date. METHODS:Two cases of advanced colorectal carcinoma with humoral hypercalcemia of malignancy (HHM) are presented. RESULTS:The two patients had severe hypercalcemia with...

journal_title：Cancer

authors： Lortholary AH,Cadeau SD,Bertrand GM,Guerin-Meyer VI,Gamelin EC,Audran MJ

更新日期：1999-12-01 00:00:00

abstract：BACKGROUND:For certain types of cancer, resection alone rarely achieves a cure, but patients nevertheless tend to have a prolonged survival before they die of the tumor. For other types of cancer, the opposite scenario prevails, suggesting that those biologic mechanisms that allow a curative resection are not identical...

journal_title：Cancer

authors： Gamel JW,McLean IW,McCurdy JB

更新日期：1993-04-01 00:00:00

abstract：BACKGROUND:Because studies have suggested that anemia has an adverse effect on outcome for patients with cervical carcinoma who are treated with radiation, recombinant human erythropoietin (rHuEpo) has been used increasingly to maintain hemoglobin levels in these patients. Erythropoietin may increase the risk of thromb...

journal_title：Cancer

authors： Wun T,Law L,Harvey D,Sieracki B,Scudder SA,Ryu JK

更新日期：2003-10-01 00:00:00

abstract：BACKGROUND:The experience of one institution in treating soft tissue sarcomas of the head and neck in a pediatric population is presented. METHODS:Case materials of 134 patients younger than 20 years who were referred to the University of Texas M. D. Anderson Cancer Center between 1970 and 1989 for treatment of sarcom...

journal_title：Cancer

authors： Lyos AT,Goepfert H,Luna MA,Jaffe N,Malpica A

更新日期：1996-01-01 00:00:00

abstract：:Methionine-depleting total parenteral nutrition (methionine-depleting TPN), which infuses an amino acid solution devoid of L-methionine and L-cysteine as the sole protein source, showed enhancement of the effect of several anti-cancer agents. In this study, the combined effect of the methionine-depleting TPN with the ...

journal_title：Cancer

authors： Goseki N,Yamazaki S,Endo M,Onodera T,Kosaki G,Hibino Y,Kuwahata T

更新日期：1992-04-01 00:00:00

abstract：:A summary is presented of those organ specific enzyme assays traditionally used in evaluation of the patient with cancer. In addition, the use of certain serum enzymes such as gamma-glutamyl transpeptidase, phosphohexose isomerase or 5'-nucleotidase as aids in following the course of the disease, particularly in patie...

journal_title：Cancer

authors： Schwartz MK

更新日期：1976-01-01 00:00:00

abstract：:Seventy three patients with disseminated diffuse non-Hodgkin's lymphomas were treated with combinations of cyclophosphamide, vincristine sulfate, prednisone, and doxorubicin with and without 2 weekly doses of oral methotrexate in "intermediate" doses, followed by calcium leucovorin rescue. The addition of methotrexate...

journal_title：Cancer

authors： Gomez GA,Barcos M,Han T,Henderson ES

更新日期：1987-07-01 00:00:00

abstract：:Long-term vocational achievements of 40 survivors of cancer diagnosed during adolescence were examined and compared with 40 healthy sex-matched and age-matched controls. Patients' ages at diagnosis ranged from 13 to 19 years (mean, 16.15). Study subjects had survived cancer for over 5 years and were on no cancer thera...

journal_title：Cancer

authors： Tebbi CK,Bromberg C,Piedmonte M

更新日期：1989-01-01 00:00:00

abstract：:The European Organization for Research on Treatment of Cancer (EORTC) trial 20781, concerning osteosarcoma of the limbs is reported. After definitive treatment of the primary tumor with amputation or irradiation, adjuvant treatment was given, randomized into either 9 months of chemotherapy according to a modified Rose...

journal_title：Cancer

authors： Burgers JM,van Glabbeke M,Busson A,Cohen P,Mazabraud AR,Abbatucci JS,Kalifa C,Tubiana M,Lemerle JS,Voûte PA

更新日期：1988-03-01 00:00:00

abstract：BACKGROUND:The appearance of p53 mutations in colorectal carcinoma was determined, independent of differentiation and tumor stage of the primary tumors, in relation to the survival of patients who were scheduled to undergo liver resection. METHODS:Tumor material was analyzed for p53 mutations in primary colorectal tum...

journal_title：Cancer

authors： Yang Y,Forslund A,Remotti H,Lönnroth C,Andersson M,Brevinge H,Svanberg E,Lindnér P,Hafström L,Naredi P,Lundholm K

更新日期：2001-02-15 00:00:00

abstract：:The prognostic importance of various factors was analyzed for 347 patients registered by the Mycosis Fungoides Cooperative Group (MFCG). Extent of skin involvement at the time of registration and number of sites of clinically enlarged lymph nodes were clearly the most important prognostic variables, and were combined ...

journal_title：Cancer

authors： Green SB,Byar DP,Lamberg SI

更新日期：1981-06-01 00:00:00

abstract：:Between June 1977 and December 1978, occult testicular leukemia (OTL) was discovered at three years of continual complete remission (CCR) from the time of diagnosis of acute lymphoblastic leukemia (ALL) in 5 of 59 (8.5%) of males undergoing bilateral wedge testicular biopsy at 1 of 15 participating Southwest Oncology ...

journal_title：Cancer

authors： Askin FB,Land VJ,Sullivan MP,Ragab AH,Steuber CP,Dyment PG,Talbert J,Moore T

更新日期：1981-02-01 00:00:00

abstract：:A growing body of research shows that a majority of patients with cancer report having religious and spiritual (R/S) beliefs, engaging in R/S behaviors, or deriving comfort from R/S experiences. These studies have been reviewed but not subjected to rigorous critical analysis. A meta-analytic approach is needed to prov...

journal_title：Cancer

authors： Salsman JM,Fitchett G,Merluzzi TV,Sherman AC,Park CL

更新日期：2015-11-01 00:00:00

abstract：BACKGROUND:Several studies have recently reported on the importance of quality of life (QOL) in predicting the survival of patients with lung carcinoma. To confirm these reports, the relationship between survival and QOL, as measured by the European Organization for Research and Treatment of Cancer (EORTC) Quality of L...

journal_title：Cancer

authors： Herndon JE 2nd,Fleishman S,Kornblith AB,Kosty M,Green MR,Holland J

更新日期：1999-01-15 00:00:00

abstract：:The yield of additional information from anteroposterior full-lung tomograms that changed stage or treatment, in comparison to that obtained from routine chest radiographs, was prospectively evaluated in 243 previously untreated patients with Hodgkin's disease and non-Hodgkin's lymphoma. Although new information was f...

journal_title：Cancer

authors： Castellino RA,Filly R,Blank N

更新日期：1976-09-01 00:00:00

abstract：BACKGROUND:Immediate or early postmastectomy breast reconstruction is performed infrequently. To the authors' knowledge, little is known regarding surgeon or patient perspectives on reconstruction treatment decisions. The purpose of the current study was to identify patient attitudes and preferences associated with bre...

journal_title：Cancer

authors： Morrow M,Mujahid M,Lantz PM,Janz NK,Fagerlin A,Schwartz K,Liu L,Deapen D,Salem B,Lakhani I,Katz SJ

更新日期：2005-12-01 00:00:00

abstract：BACKGROUND:Studies regarding different ethnic populations of children with Wilms' tumor (WT) in the U. S. have shown differences between age and gender incidence and the type of its precursor lesions (nephrogenic rests). To the authors' knowledge there are few reports in the literature regarding nephrogenic rests in a ...

journal_title：Cancer

authors： Mishra K,Mathur M,Logani KB,Kakkar N,Krishna A

更新日期：1998-11-15 00:00:00

abstract：:Neuroendocrine small cell carcinoma is a lethal, but rare, tumor that arises most frequently in the lung. Small cell cancer also rarely may occur in the female genital tract, usually in the cervix. This article concerns the fourth reported case of neuroendocrine small cell carcinoma of the vulva. Previously, small cel...

journal_title：Cancer

authors： Cliby W,Soisson AP,Berchuck A,Clarke-Pearson DL

更新日期：1991-05-01 00:00:00

abstract：BACKGROUND:Tamoxifen is a prototypic cancer chemopreventive agent, yet clinical trials have not evaluated its effect on mortality or the impact of drug pricing on its cost-effectiveness. METHODS:A state-transition Markov model for a hypothetical cohort of women age 50 years was used to evaluate the effects of tamoxife...

journal_title：Cancer

authors： Melnikow J,Kuenneth C,Helms LJ,Barnato A,Kuppermann M,Birch S,Nuovo J

更新日期：2006-09-01 00:00:00

abstract：:Fifty patients with non resectable and/or inoperable bronchogenic carcinoma were entered into a feasibility study of cisplatin (CDDP) given in continuous infusion with concurrent radiation therapy. The radiation therapy regimen consisted of 2 Gy given 5 days a week in the first 3 and last 2 weeks of a 7-week split cou...

journal_title：Cancer

authors： Bedini AV,Tavecchio L,Milani F,Gramaglia A,Spreafico C,Marchianò A,Ravasi G

更新日期：1991-01-15 00:00:00

abstract：BACKGROUND:The management of children with hypothalamic (H) and/or chiasmatic (C) tumors remains controversial. We evaluated the impact of clinical and neuroimaging parameters and primary therapy on overall (OS) and progression-free (PFS) survival and on neuroendocrine and neurocognitive outcome in children with H and/...

journal_title：Cancer

authors： Fouladi M,Wallace D,Langston JW,Mulhern R,Rose SR,Gajjar A,Sanford RA,Merchant TE,Jenkins JJ,Kun LE,Heideman RL

更新日期：2003-02-15 00:00:00

abstract：BACKGROUND:Although several refinements have been reported for breast magnetic resonance imaging (MRI), there has been no uniform agreement by researchers on the optimal method. The authors report a simple and effective MRI method that incorporated the best qualities of other breast MRI methods yet eliminated the compl...

journal_title：Cancer

authors： Khatri VP,Stuppino JJ,Espinosa MH,Pollack MS

更新日期：2001-08-01 00:00:00

abstract：BACKGROUND:Activation of telomerase, a ribonucleoprotein enzyme complex that synthesizes telomere repeats, is associated with acquisition of unlimited cellular proliferation and is commonly detected in human cancer. Measurement of telomerase activity (TA) may provide important information as a diagnostic marker or a pr...

journal_title：Cancer

authors： Shoji Y,Yoshinaga K,Inoue A,Iwasaki A,Sugihara K

更新日期：2000-03-15 00:00:00

abstract：:To examine the relationship between smoking and stage of colorectal cancer at diagnosis, data on 2788 current smokers and 6313 nonsmokers with known stage at diagnosis were obtained from the Massachusetts Cancer Registry. The stage at diagnosis was treated as a polytomous response variable in a logit-type, log-linear ...

journal_title：Cancer

authors： Longnecker MP,Clapp RW,Sheahan K

更新日期：1989-09-15 00:00:00

abstract：:Over the last decade, new cytotoxic treatments and targeted therapies have altered treatment paradigms for patients with metastatic non-small cell lung cancer (NSCLC). We sought to analyze the impact of histology and biomarker selection criteria on outcomes of clinical trials in metastatic NSCLC reported over the last...

journal_title：Cancer

authors： Gentzler RD,Yentz SE,Johnson ML,Rademaker AW,Patel JD

更新日期：2014-12-15 00:00:00

abstract：BACKGROUND:Resistance to apoptosis is 1 of the key events that confer chemoresistance and is mediated by the overexpression of antiapoptotic proteins, which inhibit caspase activation. The objective of this study was to evaluate whether the activation of an alternative, caspase-independent cell death pathway could prom...

journal_title：Cancer

authors： Alvero AB,Montagna MK,Chen R,Kim KH,Kyungjin K,Visintin I,Fu HH,Brown D,Mor G

更新日期：2009-07-15 00:00:00

abstract：BACKGROUND:The delivery of effective treatment for pediatric solid tumors poses a particular challenge to centers in middle-income countries (MICs) that already are vigorously addressing pediatric cancer. The objective of this study was to improve the current understanding of barriers to effective treatment of pediatri...

journal_title：Cancer

authors： Friedrich P,Ortiz R,Fuentes S,Gamboa Y,Ah Chu-Sanchez MS,Arambú IC,Montero M,Báez F,Rodríguez-Galindo C,Antillón-Klussmann F,Central American Association of Pediatric Hematologists and Oncologists (AHOPCA).

更新日期：2014-01-01 00:00:00

abstract：:Nineteen postmenopausal patients with metastatic breast cancer refractory to conventional combination chemotherapy were treated with monthly cycles with the combinations of vinblastine, adriamycin, thiotepa and halotestin. Ten patients (52%) responded with a greater than 50% regression of measurable tumor. The median ...

journal_title：Cancer

authors： Perloff M,Hart RD,Holland JF

更新日期：1978-12-01 00:00:00

abstract：BACKGROUND:Adjuvant radiation has been proposed for the treatment of patients with desmoplastic melanoma, who reportedly have local recurrence rates as high as 40-60%. The authors investigated local recurrence rates at a tertiary referral center to determine the success of wide excision alone for patients with desmopla...

journal_title：Cancer

authors： Arora A,Lowe L,Su L,Rees R,Bradford C,Cimmino VC,Chang AE,Johnson TM,Sabel MS

更新日期：2005-10-01 00:00:00

abstract：:Eight cases of primary non-Hodgkin's lymphoma of the breast found in the pathology files of the Institute of Oncology, Ljubljana, Yugoslavia, for a period of 25 years (from 1961 to 1985) were analyzed. During the same period 5711 cases of breast carcinoma were seen. Seven cases were diffuse lymphomas, and one case was...

journal_title：Cancer

authors： Lamovec J,Jancar J

更新日期：1987-12-15 00:00:00