Biologic distinctions between cure and time to death in 2892 patients with intraocular melanoma.

abstract：:Venous thromboembolism (VTE) is a frequent complication of cancer and cancer treatment and is associated with multiple clinical consequences, including recurrent VTE, bleeding, and an increase in the risk of death. Although the risks associated with VTE have been well recognized in surgical cancer patients, there is a...

journal_title：Cancer

authors： Lyman GH

更新日期：2009-12-15 00:00:00

abstract：BACKGROUND:Studies of colorectal adenocarcinoma (CRC) indicate a higher mortality rate for African Americans compared with Caucasians in the United States. In the current study, the authors evaluated the racial differences in survival based on tumor location and pathologic stage between African-American patients and Ca...

journal_title：Cancer

authors： Alexander D,Chatla C,Funkhouser E,Meleth S,Grizzle WE,Manne U

更新日期：2004-07-01 00:00:00

abstract：BACKGROUND:Tamoxifen is a prototypic cancer chemopreventive agent, yet clinical trials have not evaluated its effect on mortality or the impact of drug pricing on its cost-effectiveness. METHODS:A state-transition Markov model for a hypothetical cohort of women age 50 years was used to evaluate the effects of tamoxife...

journal_title：Cancer

authors： Melnikow J,Kuenneth C,Helms LJ,Barnato A,Kuppermann M,Birch S,Nuovo J

更新日期：2006-09-01 00:00:00

abstract：BACKGROUND:To study the correlation of environmental exposure to potentially mutagenic agents and the clinicopathologic picture in acute myeloid leukemia (AML), clinical features, morphologic characteristics, immunophenotype, and cytogenetics were studied in 59 patients with newly diagnosed AML. METHODS:Based on inter...

journal_title：Cancer

authors： Fagioli F,Cuneo A,Piva N,Carli MG,Previati R,Balboni M,Tomasi P,Cariani D,Scapoli G,Castoldi G

更新日期：1992-07-01 00:00:00

abstract：:Light microscopic, immunocytochemical and ultrastructural studies were performed on chondrosarcomas which contained a second, noncartilagenous mesenchymal component. Attention was focused on the nonchondroid portion of each tumor in an attempt to elucidate the histogenesis of this mixed variant of chondrosarcoma. The ...

journal_title：Cancer

authors： Têtu B,Ordóñez NG,Ayala AG,Mackay B

更新日期：1986-07-15 00:00:00

abstract：:The National Wilms' Tumor Study (NWTS) was initiated in 1969. One of its objectives was to modulate treatments according to risk factors to minimize the number and severity of treatment-related short-term and long-term iatrogenic complications. The NWTS has therefore incorporated a Long Term Follow-up Study (LTFS) wit...

journal_title：Cancer

authors： Evans AE,Norkool P,Evans I,Breslow N,D'Angio GJ

更新日期：1991-01-15 00:00:00

abstract：:The experience of 260 patients with endometrial carcinoma was reviewed. The influence of factors such as age, stage of disease, grade and degree of myometrial penetration on the survival was presented, showing that survival decreases in elderly patients, in patients with advanced stage of disease, when the tumor is un...

journal_title：Cancer

authors： Tavares MA,Patricio MB,Vilhena M,Da Silva JN

更新日期：1977-02-01 00:00:00

abstract：:Fluorescence polarization was performed on 82 individuals: 32 patients with malignant diseases, 30 apparently healthy individuals, and 20 patients with nonmalignant diseases. The blood lymphocytes from these cases were isolated and challenged with cancer basic protein (CaBP). Stimulation occurred in the majority of th...

journal_title：Cancer

authors： Schnuda ND

更新日期：1980-09-01 00:00:00

abstract：:Eighty-one primary ovarian carcinoids and intraovarian metastases from six mid-gut carcinoids were examined for the presence of tumor cells immunoreactive with antisera raised against various neurohormonal peptides, mostly of gastroenteropancreatic (GEP) origin. Twenty of the primary and two of the metastatic carcinoi...

journal_title：Cancer

authors： Sporrong B,Falkmer S,Robboy SJ,Alumets J,Håkanson R,Ljungberg O,Sundler F

更新日期：1982-01-01 00:00:00

abstract：:Tumor weight, carcass weight, nitrogen balance, energy balance, resting energy expenditure (REE), and activity energy expenditure (AEE) were measured in normal Fischer 344 rats, free-feeding Fischer 344 rats with methylcholanthrene-induced sarcoma (TB-FF), and similar tumor-bearing rats supported with total parenteral...

journal_title：Cancer

authors： Popp MB,Brennan MF,Morrison SD

更新日期：1982-03-15 00:00:00

abstract：:Lethal midline granuloma (LMG), initially a clinical description, includes an uncommon group of disorders characterized by a relentless, destructive process involving the upper respiratory structures. Its etiology and pathogenesis are uncertain, probably varied, and the distinction between inflammatory and malignant p...

journal_title：Cancer

authors： Lippman SM,Grogan TM,Spier CM,Koopmann CF Jr,Gall EP,Shimm DS,Durie BG

更新日期：1987-03-01 00:00:00

abstract：BACKGROUND:The diagnostic accuracy of technetium-99m methoxyisobutylisonitrile (Tc-MIBI) single photon emission computed tomography (SPECT) and computed tomography (CT) of the head and neck for differentiating recurrent or residual nasopharyngeal carcinomas (NPC) from benign lesions after radiotherapy was compared with...

journal_title：Cancer

authors： Kao CH,Shiau YC,Shen YY,Yen RF

更新日期：2002-04-01 00:00:00

abstract：:Patients with ulcerative colitis are at increased risk of developing adenocarcinoma of the colon. The authors describe a patient whose colonic neoplasm demonstrated histologic characteristics of both an adenocarcinoma and a carcinoid tumor and which was pathologically identical to a appendiceal adenocarcinoid. Because...

journal_title：Cancer

authors： Lyss AP,Thompson JJ,Glick JH

更新日期：1981-08-01 00:00:00

abstract：:Tumor-bearing patients with breast cancer were assayed for their natural killer (NK) cell activity and for the function of activated cytotoxic T-cells, as assessed by lectin-dependent cellular cytotoxicity (LDCC). Tumor-bearing patients with breast cancer had a significant increase in NK activity and in LDCC, as compa...

journal_title：Cancer

authors： Zielinski CC,Tichatschek E,Müller C,Kalinowski W,Sevelda P,Czerwenka K,Kubista E,Spona J

更新日期：1989-05-15 00:00:00

abstract：:It was shown previously that invasive human transitional cell carcinoma cell line EJ, but not the noninvasive RT4 cells, can degrade basement membrane laminin and that the degradation of basement membrane laminin was a result of a redistribution of activated cysteine proteinase cathepsin B to the plasma membrane of th...

journal_title：Cancer

authors： Redwood SM,Liu BC,Weiss RE,Hodge DE,Droller MJ

更新日期：1992-03-01 00:00:00

abstract：BACKGROUND:A phase 2 trial was carried out to assess the antineoplastic activity of 2 courses of cyclophosphamide-etoposide in relapsed osteosarcoma patients. METHODS:Twenty-six relapsed osteosarcoma patients with a median age of 18.5 years (8.3-47.1) were enrolled. Seven patients were in first relapse (27%), 11 in se...

journal_title：Cancer

authors： Berger M,Grignani G,Ferrari S,Biasin E,Brach del Prever A,Aliberti S,Saglio F,Aglietta M,Fagioli F

更新日期：2009-07-01 00:00:00

abstract：BACKGROUND:Osteosarcomas are typically long bone tumors and rarely affect the skull, with most articles reporting single cases. As elsewhere in the body, these lesions may be classified as primary or secondary, chiefly post-Paget and post-radiation therapy. METHODS:The authors reviewed the osteosarcomas of the skull d...

journal_title：Cancer

authors： Salvati M,Ciappetta P,Raco A

更新日期：1993-04-01 00:00:00

abstract：BACKGROUND:Previous studies have shown that low levels of p27(Kip1), an inhibitor of G1 cyclin-dependent kinases, are associated with high aggressiveness and poor prognosis in a variety of cancers. Decreased levels of p27 are caused, at least in part, by acceleration of the rate of its ubiquitin-mediated degradation. I...

journal_title：Cancer

authors： Hershko D,Bornstein G,Ben-Izhak O,Carrano A,Pagano M,Krausz MM,Hershko A

更新日期：2001-05-01 00:00:00

abstract：BACKGROUND:Improvements in quality of life after treatment with recombinant human erythropoietin (rHuEPO) often have been reported in patients with end-stage renal disease. In patients with chronic anemia of cancer, comparatively few systemic investigations have been performed. METHODS:Various aspects of quality of li...

journal_title：Cancer

authors： Leitgeb C,Pecherstorfer M,Fritz E,Ludwig H

更新日期：1994-05-15 00:00:00

abstract：BACKGROUND:Nonsteroidal anti-inflammatory drugs (NSAIDs) may prevent the development of cancer by inhibiting cyclooxygenase (COX) enzymes, which are involved in carcinogenesis. Therefore, the authors of this report examined the association between NSAID use and the risk of squamous cell carcinoma (SCC), basal cell carc...

journal_title：Cancer

authors： Johannesdottir SA,Chang ET,Mehnert F,Schmidt M,Olesen AB,Sørensen HT

更新日期：2012-10-01 00:00:00

abstract：:Malignant salivary gland neoplasms in children are rare. Such tumors usually occur in the parotid gland of older children. Sixteen cases of major salivary gland malignancy are reviewed, 14 occurring in the parotid gland and two in the submandibular gland. Adenoid cystic carcinoma was the most common malignancy encount...

journal_title：Cancer

authors： Baker SR,Malone B

更新日期：1985-04-15 00:00:00

abstract：:Thirty-seven patients with superficial spreading or nodular melanoma of the head and neck treated with irradiation are reviewed. Twenty-one patients were referred within three months of surgery. Six had an incisional biopsy followed by postoperative irradiation, 4 were locally controlled (1 dying of metastatic melanom...

journal_title：Cancer

authors： Harwood AR,Dancuart F,Fitzpatrick PJ,Brown T

更新日期：1981-12-15 00:00:00

abstract：:Since 1975, clinical studies have been carried out to determine whether radiation when combined with localized hyperthermia evokes improved tumor control compared to that achieved with radiation alone. Local tumor hyperthermia was achieved using radiofrequency inductive heating at 27.12 MHz. In bulky lesions (greater ...

journal_title：Cancer

authors： Kim JH,Hahn EW,Ahmed SA

更新日期：1982-08-01 00:00:00

abstract：:The prevalence of variant alkaline phosphatase in the serum of 335 southern African blacks with hepatocellular carcinoma was determined using polyacrylamide gel electrophoresis. The isoenzyme was detected in 2% (seven of 335) of the patients: it could not be found in the serum of 300 matched, healthy individuals or in...

journal_title：Cancer

authors： Bukofzer S,Kew MC,Rowe P

更新日期：1988-09-01 00:00:00

abstract：:Although clinically evident thyroid carcinoma is not a frequent neoplasm (incidence 2.7 per 100,000 persons in La Plata, Argentina), occult carcinomas are present in a high proportion of the population, but there are marked differences along geographical lines. The purpose of the present study is to establish the prev...

journal_title：Cancer

authors： Ottino A,Pianzola HM,Castelletto RH

更新日期：1989-07-15 00:00:00

abstract：BACKGROUND:Receipt of chemotherapy at the end of life (EOL) is considered an indicator of poor quality of care for medical oncology. The objective of this study was to characterize the use of radiotherapy (RT) in patients with nonsmall cell lung cancer (NSCLC) during the same period. METHODS:Treatment characteristics ...

journal_title：Cancer

authors： Kapadia NS,Mamet R,Zornosa C,Niland JC,D'Amico TA,Hayman JA

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND:Tumors consisting of a combination of malignant melanoma and carcinoma are very rare. The authors report two such cases occurring as primary breast tumors. METHODS:The breast tumors were analyzed by histologic, immunohistochemical, and ultrastructural techniques. RESULTS:Histologically, the tumors were com...

journal_title：Cancer

authors： Padmore RF,Lara JF,Ackerman DJ,Gales T,Sigurdson ER,Ehya H,Cooper HS,Patchefsky AS

更新日期：1996-12-15 00:00:00

abstract：:The survival of 78 patients with resected non-small cell lung cancer entered in prospective, randomized investigational trials is compared to that of a population-based group of control patients not included in such trials. The survival of trial patients is significantly better than that of controls (P less than 0.001...

journal_title：Cancer

authors： Davis S,Wright PW,Schulman SF,Hill LD,Pinkham RD,Johnson LP,Jones TW,Kellogg HB Jr,Radke HM,Sikkema WW

更新日期：1985-10-01 00:00:00

abstract：BACKGROUND:Crizotinib is a tyrosine kinase inhibitor active against ALK, MET, and ROS1. We previously reported that crizotinib decreases testosterone in male patients. The detailed etiology of the effect, its symptomatic significance, and the effectiveness of subsequent testosterone replacement have not been previously...

journal_title：Cancer

authors： Weickhardt AJ,Doebele RC,Purcell WT,Bunn PA,Oton AB,Rothman MS,Wierman ME,Mok T,Popat S,Bauman J,Nieva J,Novello S,Ou SH,Camidge DR

更新日期：2013-07-01 00:00:00

abstract：:The authors present the case of a 40-year-old white man with an obstructing laryngeal mass. Despite considerable tumor size, results of repeated biopsies revealed widespread carcinoma in situ with chronic inflammation within the subcutaneous tissues, and only after extensive endoscopic "debulking" of the mass was a sm...

journal_title：Cancer

authors： Eskinazi DP,Mihail R,Dichtel WG

更新日期：1985-08-01 00:00:00