Abrogation of the invasion of human bladder tumor cells by using protease inhibitor(s).

abstract：:Two cases of extraskeletal myxoid chondrosarcoma are reported. The patients presented with metastasis to the lung, 10 years and 2 years, respectively, prior to discovery of the primary neoplasms in the soft tissues of the lower extremities. ...

journal_title：Cancer

authors： D'Ambrosio FG,Shiu MH,Brennan MF

更新日期：1986-09-01 00:00:00

abstract：:Fifteen oncocytic (oxyphilic granular cell) neoplasms of the salivary glands collected from three large university medical centers are presented. The histologic and ultrastructural criteria that characterize oncocytes are presented and electron micrographs of two of our cases are discussed. Included in the series are ...

journal_title：Cancer

authors： Gray SR,Cornog JL Jr,Seo IS

更新日期：1976-09-01 00:00:00

abstract：:A study of 112 biopsy specimens from Danish oral leukoplakia patients and 145 biopsy specimens from Indian leukoplakia patients revealed a chevron-like keratinization of the epithelium in a number of cases. Clinically, this type of keratinization was often characterized by a pumice-like appearance. The clinical and hi...

journal_title：Cancer

authors： Pindborg JJ,Reibel J,Roed-Peterson B,Mehta FS

更新日期：1980-05-01 00:00:00

abstract：BACKGROUND:The efficacy of the current 6th edition of the American Joint Committee on Cancer (AJCC) tumor staging criteria in improving outcome prediction for patients with oropharyngeal cancer was analyzed. METHODS:From the database of the Department of Radiation Oncology at the University of Texas M. D. Anderson Can...

journal_title：Cancer

authors： Asper JA,Morrison WH,Rosenthal DI,Ahamad A,Ang KK,Garden AS

更新日期：2006-05-01 00:00:00

abstract：:DNA ploidy and percent of (%S-phase) S-phase cells were determined from the DNA content distribution of 21 benign and 76 malignant (69 primary, 7 metastatic) breast tumors using flow cytometry. All of the benign tumors were diploid, whereas 89% of the malignant tumors had measurable aneuploidy. Multiple stem-lines wer...

journal_title：Cancer

authors： Moran RE,Black MM,Alpert L,Straus MJ

更新日期：1984-10-15 00:00:00

abstract：:Thirty-eight patients with metastatic colorecal carcinoma were treated with 5-fluorouracil (5-FU), and 38 patients were treated with the combination of 5-FU, cyclophosphamide, and methotrexate. In terms of percent response, response duration, and survival there was no apparent difference between the two regimens. Comb...

journal_title：Cancer

authors： Richards F 2nd,Pajak TL,Cooper MR,Spurr CL

更新日期：1975-11-01 00:00:00

abstract：:Two cases of primary non-Hodgkin's lymphomas of the breast were studied with light and electron microscopy. By light microscopy, according to Rappaport's classification, one was a poorly differentiated lymphocytic lymphoma, the other a diffuse histiocytic lymphoma. However, the ultrastructural features of the latter w...

journal_title：Cancer

authors： Navas JJ,Battifora H

更新日期：1977-05-01 00:00:00

abstract：:Forty-milligram strips of malignant breast tissue were divided longitudinally into 20-mg microsamples. Soluble protein concentration was determined for one-half, and histologic evaluation for viable carcinoma content was made on its sister half. The correlation coefficient for 88 such comparisons was 0.330. This sugge...

journal_title：Cancer

authors： van Netten JP,Algard FT,Coy P,Carlyle SJ,Brigden ML,Thornton KR,To MP

更新日期：1982-06-01 00:00:00

abstract：BACKGROUND:Childhood cancer is a highly curable disease when timely diagnosis and appropriate therapy are provided. A negative impact of the coronavirus disease 2019 (COVID-19) pandemic on access to care for children with cancer is likely but has not been evaluated. METHODS:A 34-item survey focusing on barriers to ped...

journal_title：Cancer

authors： Saab R,Obeid A,Gachi F,Boudiaf H,Sargsyan L,Al-Saad K,Javakhadze T,Mehrvar A,Abbas SS,Abed Al-Agele YS,Al-Haddad S,Al Ani MH,Al-Sweedan S,Al Kofide A,Jastaniah W,Khalifa N,Bechara E,Baassiri M,Noun P,El-Houdzi J,K

更新日期：2020-09-15 00:00:00

abstract：BACKGROUND:The reported frequency of gastrointestinal (GI) tract involvement in patients with mantle cell lymphoma (MCL) is 15-30%. However, this figure most likely is an underestimate because most patients with MCL involving the GI tract previously reported were examined endoscopically only if they had GI tract sympto...

journal_title：Cancer

authors： Romaguera JE,Medeiros LJ,Hagemeister FB,Fayad LE,Rodriguez MA,Pro B,Younes A,McLaughlin P,Goy A,Sarris AH,Dang NH,Samaniego F,Brown HM,Gagneja HK,Cabanillas F

更新日期：2003-02-01 00:00:00

abstract：BACKGROUND:Transitional cell carcinoma (TCC) is rare in the female genital tract. Although it is most common in the ovary, small series of cases in the cervix have been reported, with isolated cases described in the fallopian tube, adnexa uteri, and endometrium. METHODS:Eight cases of primary TCC involving the endomet...

journal_title：Cancer

authors： Lininger RA,Ashfaq R,Albores-Saavedra J,Tavassoli FA

更新日期：1997-05-15 00:00:00

abstract：BACKGROUND:To evaluate the immunologic activity of regional lymph nodes, the phenotype of lymphocytes and the functional expression of cell adhesion molecules (CAMs) on lymph node lymphocytes (LNL-: uninvolved, LNL+: involved) were investigated in patients with gastrointestinal carcinoma. METHODS:The lymphocyte subpop...

journal_title：Cancer

authors： Shinkal H,Kitayama J,Kimura W,Muto T,Shibata Y

更新日期：1996-10-15 00:00:00

abstract：BACKGROUND:Amplification of DNA in certain chromosomal regions plays a crucial role in the development and progression of human malignancies, specifically when protooncogenic target genes within those amplicons are overexpressed. Comparative genomic hybridization studies have revealed frequent amplification at 20q in p...

journal_title：Cancer

authors： Zhao C,Yasui K,Lee CJ,Kurioka H,Hosokawa Y,Oka T,Inazawa J

更新日期：2003-07-01 00:00:00

abstract：:Six patients with metastatic mixed germ-cell tumors who had been treated successfully with chemotherapy had recurring solitary enlarging masses. Four had enlarging pulmonary masses and two patients had enlarging abdominal masses. Each had the presumed chemotherapy refractory mass surgically resected and was found to h...

journal_title：Cancer

authors： Logothetis CJ,Samuels ML,Trindade A,Johnson DE

更新日期：1982-10-15 00:00:00

abstract：:Few studies have incorporated high-dose methotrexate (MTX) with leucovorin rescue in the treatment of small cell lung cancer (SCLC). Potentially therapeutic levels of MTX can be achieved in the central nervous system (CNS) by systemic administration of high doses of this drug. Utilizing a combination chemotherapy prog...

journal_title：Cancer

authors： Neijstrom ES,Capizzi RL,Rudnick SA,Kirsch M,Delaney D,Kahn L,Lipper S,Carney C

更新日期：1983-03-15 00:00:00

abstract：:We counted the number of toluidine blue positive mast cells within and around the tumor in 44 patients with soft tissue sarcomas (STS). Irrespective of their histologic types, these cases were broadly divided into the following two groups: (1) low count (less than 20 mast cells/10 high-power fields [HPF]) and (2) high...

journal_title：Cancer

authors： Ueda T,Aozasa K,Tsujimoto M,Yoshikawa H,Kato T,Ono K,Matsumoto K

更新日期：1988-12-01 00:00:00

abstract：BACKGROUND:Oral premalignant lesions (OPLs) are precursors of oral squamous cell carcinoma (OSCC). Short telomeres in peripheral blood leukocytes (PBLs) are associated with increased risks of several cancers. However, it is unclear whether short leukocyte telomere length (LTL) predisposes individuals to OPL and OSCC. ...

journal_title：Cancer

authors： Bau DT,Lippman SM,Xu E,Gong Y,Lee JJ,Wu X,Gu J

更新日期：2013-12-15 00:00:00

abstract：BACKGROUND:The activation of the clotting-fibrinolytic system in cancer patients is common and represents an unfavorable clinical sign. D-dimer (DD) is a sensitive marker of fibrinolysis. METHODS:The current study comprised 826 new lung carcinoma patients seen consecutively in a single institution over a 10-year perio...

journal_title：Cancer

authors： Buccheri G,Torchio P,Ferrigno D

更新日期：2003-06-15 00:00:00

abstract：BACKGROUND:We recently reported that peroxisome proliferator-activated receptor γ agonists target chronic myeloid leukemia (CML) quiescent stem cells in vitro by decreasing transcription of STAT5. Here in the ACTIM phase 2 clinical trial, we asked whether pioglitazone add-on therapy to imatinib would impact CML residua...

journal_title：Cancer

authors： Rousselot P,Prost S,Guilhot J,Roy L,Etienne G,Legros L,Charbonnier A,Coiteux V,Cony-Makhoul P,Huguet F,Cayssials E,Cayuela JM,Relouzat F,Delord M,Bruzzoni-Giovanelli H,Morisset L,Mahon FX,Guilhot F,Leboulch P,French

更新日期：2017-05-15 00:00:00

abstract：:The effectiveness of combined modality therapy was studied in 29 patients with metastatic extradural spinal tumor who had had a previous diagnosis of malignancy. Dexamethasone was begun upon suspicion of the diagnosis in a dose of 40 mg daily. Following emergency myelography, in all patients without rapid progression,...

journal_title：Cancer

authors： Marshall LF,Langfitt TW

更新日期：1977-11-01 00:00:00

abstract：BACKGROUND:Telomerase is commonly recognized as an effective anticancer target. The human telomerase reverse transcriptase (hTERT), the rate-limiting component of telomerase, is expressed in most malignant tumors, but it is not found in most normal somatic cells. Here, we report a real-time and noninvasive method to mo...

journal_title：Cancer

authors： Yu ST,Li C,Lü MH,Liang GP,Li N,Tang XD,Wu YY,Shi CM,Chen L,Li CZ,Cao YL,Fang DC,Yang SM

更新日期：2012-04-01 00:00:00

abstract：BACKGROUND:In this study, the authors evaluated the clinical presentation of patients with T4b breast carcinoma, analyzed the impact of noninflammatory skin involvement on long-term survival, and addressed the question whether the T4 tumor category still has any justification. METHODS:The clinical course of a study gr...

journal_title：Cancer

authors： Guth U,Wight E,Schotzau A,Langer I,Dieterich H,Rochlitz C,Herberich L,Holzgreve W,Singer G

更新日期：2005-11-01 00:00:00

abstract：:Six cases of desmoplastic melanoma were studied by light and electron microscopy. The tumors fulfilled one or more of the following criteria: (1) having the presence of atypical intraepidermal melanocytic proliferation bordering the primary lesions; (2) an antecedent history of melanoma at the site of recurrence; (3) ...

journal_title：Cancer

authors： DiMaio SM,Mackay B,Smith JL Jr,Dickersin GR

更新日期：1982-12-01 00:00:00

abstract：BACKGROUND:Cervical carcinoma remains a significant health risk for the older woman. In the current study the yield of screening of mature women in an established, opportunistic screening program was examined. Strategies for improving screening in this age group were identified through examination of recent Pap test hi...

journal_title：Cancer

authors： Colgan TJ,Clarke A,Hakh N,Seidenfeld A

更新日期：2002-08-25 00:00:00

abstract：BACKGROUND:Several studies have demonstrated that abnormal levels of nuclear matrix protein 22 (NMP22) are associated with bladder cancer and have led to the approval of NMP22 as a urinary biomarker by the US Food and Drug Administration. Nonetheless, the clinical significance of NMP22 remains unclear. The objective of...

journal_title：Cancer

authors： Shariat SF,Savage C,Chromecki TF,Sun M,Scherr DS,Lee RK,Lughezzani G,Remzi M,Marberger MJ,Karakiewicz PI,Vickers AJ

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND:Few previous articles have analyzed the relation between infection with Helicobacter pylori (H. pylori) and primary gastric lymphoma in a large number of patients. METHODS:Resected and biopsied specimens from 237 patients with primary gastric lymphoma were investigated for H. pylori using hematoxylin and eo...

journal_title：Cancer

authors： Nakamura S,Yao T,Aoyagi K,Iida M,Fujishima M,Tsuneyoshi M

更新日期：1997-01-01 00:00:00

abstract：BACKGROUND:Studies regarding different ethnic populations of children with Wilms' tumor (WT) in the U. S. have shown differences between age and gender incidence and the type of its precursor lesions (nephrogenic rests). To the authors' knowledge there are few reports in the literature regarding nephrogenic rests in a ...

journal_title：Cancer

authors： Mishra K,Mathur M,Logani KB,Kakkar N,Krishna A

更新日期：1998-11-15 00:00:00

abstract：:First implemented in 1990, patient navigation interventions are emerging today as an approach to reduce cancer disparities. However, there is lack of consensus about how patient navigation is defined, what patient navigators do, and what their qualifications should be. Little is known about the efficacy and cost-effec...

journal_title：Cancer

authors： Wells KJ,Battaglia TA,Dudley DJ,Garcia R,Greene A,Calhoun E,Mandelblatt JS,Paskett ED,Raich PC,Patient Navigation Research Program.

更新日期：2008-10-15 00:00:00

abstract：:Sixty-four adult patients with refractory acute lymphocytic leukemia (ALL) received salvage therapy with the vincristine, doxorubicin (Adriamycin, Adria Laboratories, Columbus, OH), and dexamethasone (VAD) regimen consisting of induction chemotherapy with the three agents followed by multiple-agent maintenance therapy...

journal_title：Cancer

authors： Kantarjian HM,Walters RS,Keating MJ,Barlogie B,McCredie KB,Freireich EJ

更新日期：1989-07-01 00:00:00

abstract：:Ninety-five patients with non-oat cell lung cancer underwent resection of all apparent disease and were followed for a minimum of 36 months. Incidence of recurrence was 34% in 47 patients with N0 disease, 65% in 32 patients with N1 disease, and 81.3% in 16 patients with N2 disease (P less than 0.02 and P less than 0.0...

journal_title：Cancer

authors： Iascone C,DeMeester TR,Albertucci M,Little AG,Golomb HM

更新日期：1986-02-01 00:00:00