Vinblastine, adriamycin, thiotepa, and halotestin (VATH): therapy for advanced breast cancer refractory to prior chemotherapy.

abstract：:Diagnostic advances currently have exceeded therapeutic gain. The present, however, is a transition phase. Chemotherapy, for example, has become curative for some tumors in recent years, rather than merely palliative, due to the precision permitted by advances in molecular biology. At this time, acceleration in the ba...

journal_title：Cancer

authors： Gusberg SB

更新日期：1987-10-15 00:00:00

abstract：BACKGROUND:Myeloma survival varies markedly with International Staging System classification, presence of cytogenetic abnormalities, and, especially, gene expression profiling-based risk and delTP53 status, whose collective impact has not been examined in the context of specific therapies. METHODS:The authors examined...

journal_title：Cancer

authors： Waheed S,Shaughnessy JD,van Rhee F,Alsayed Y,Nair B,Anaissie E,Szymonifka J,Hoering A,Crowley J,Barlogie B

更新日期：2011-03-01 00:00:00

abstract：:Detailed cytogenetic studies were performed in 41 patients with cutaneous T-cell lymphoma (CTCL): four patients had limited plaques, 13 patients had generalized plaques, eight patients had cutaneous tumors, 16 patients had generalized erythroderma, and four additional patients, who had relatively benign chronic dermat...

journal_title：Cancer

authors： Whang-Peng J,Bunn PA Jr,Knutsen T,Matthews MJ,Schechter G,Minna JD

更新日期：1982-10-15 00:00:00

abstract：:Twenty-two cases of breast tumor with infiltrating lobular carcinoma were studied. Thirteen showed the classic single-file pattern as a sole component, and 6 as a predominant pattern; the less common confluent pattern was found in 3 instances as a predominant component. Mucin secretion was evidenced in 59% of the prim...

journal_title：Cancer

authors： Van Bogaert LJ,Maldague P

更新日期：1980-03-01 00:00:00

abstract：METHODS:Between 1983 and 1989, 42 patients with Stage II, III, and IV, node-negative, squamous cell head and neck cancer were treated with concurrent 5-fluorouracil, cisplatin, and radiation therapy. Two courses of chemotherapy with 30 Gy of concurrent radiation therapy were to be followed in all patients by definitive...

journal_title：Cancer

authors： Adelstein DJ,Sharan VM,Damm C,Earle AS,Shah AC,Haria CD,Trey JE,Carter SG,Hines JD

更新日期：1992-12-01 00:00:00

abstract：:Malignant thymoma is a relatively rare condition and a review of the literature reveals approximately 100 reported cases. Only a small percentage of these have been treated with megavoltage radiation therapy; therefore, it is difficult to find the necessary information to establish a proper time-dose relationship for ...

journal_title：Cancer

authors： Marks RD Jr,Wallace KM,Pettit HS

更新日期：1978-01-01 00:00:00

abstract：:International comparisons have provided striking correlations between fat consumption and risk of breast cancer, but these comparisons do not often consider variations in life style. Case-control studies carried out in several countries showed no real association between fat intake and breast cancer. There is some evi...

journal_title：Cancer

authors： Kritchevsky D

更新日期：1990-09-15 00:00:00

abstract：:A 78-year-old Japanese man with chronic liver disease developed hypervascular liver tumors accompanied by marked elevation of alphafetoprotein value (the highest level; 26200 ng/ml) and pathologic fracture of the femur. After an operation for the fracture followed by gastrointestinal bleeding and repeated transfusions...

journal_title：Cancer

authors： Sato Y,Fujiwara K,Nakagawa S,Kanishima S,Ohta Y,Oka Y,Hayashi S,Oka H

更新日期：1985-08-01 00:00:00

abstract：:The authors report an analysis of 47 leukemia patients (including 9 from our own medical center) whose courses were complicated by 48 episodes of clostridial septicemia. There were 36 adults and 11 children; acute myelogenous leukemia and acute lymphoblastic leukemia accounted for 61.7% and 14.9% of cases, respectivel...

journal_title：Cancer

authors： Caya JG,Farmer SG,Ritch PS,Wollenberg NJ,Tieu TM,Oechler HW,Spivey M

更新日期：1986-05-15 00:00:00

abstract：BACKGROUND:The carboplatin-based chemotherapeutic regimen M-CAVI (methotrexate, carboplatin, and vinblastine) is active against bladder carcinoma and can be administered to patients who are ineligible to receive cisplatin or doxorubicin. The authors designed a randomized study to evaluate whether M-CAVI offers a therap...

journal_title：Cancer

authors： Bellmunt J,Ribas A,Eres N,Albanell J,Almanza C,Bermejo B,Solé LA,Baselga J

更新日期：1997-11-15 00:00:00

abstract：:Antibodies to herpes simplex viral-induced antigens (HSVIA) were assayed by an indirect immunofluorescent technique in 93 regular cigarette smokers, 75 of whom also imbibed alcoholic beverages. Controls were 94 nonsmoking, nondrinking volunteers matched with the smoker for age and sex. IgA antibodies to HSVIA were det...

journal_title：Cancer

authors： Smith HG,Horowitz N,Silverman NA,Henson DE,Chretien PB

更新日期：1976-09-01 00:00:00

abstract：:Higher serum iron and ferritin levels noted in hepatitis B antigen (HBAg) carriers than in noncarriers suggests that virus might actively replicate in hepatocytes, stimulate ferritin synthesis, and result in increased liver iron stores. A comparative semiquantitative study of immunohistochemical ferritin (0-12) and he...

journal_title：Cancer

authors： Cohen C,Berson SD,Shulman G,Budgeon LR

更新日期：1985-11-01 00:00:00

abstract：:Oral submucous fibrosis (OSF) is a chronic disease of the oral mucosa characterized by inflammation and a progressive fibrosis of the lamina propria and deeper connective tissues. It is a condition predominantly seen among people of Indian origin, and an epidemiologic survey done a decade ago showed no less than 250,0...

journal_title：Cancer

authors： Pillai R,Balaram P,Reddiar KS

更新日期：1992-04-15 00:00:00

abstract：BACKGROUND:The clinical dose of 3-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-1-(2-chloroethyl)-1-nitro- sourea hydrochloride (ACNU) is limited by the bone marrow suppression it produces. The authors investigated whether bone marrow transplantation (BMT) associated with a high dose of ACNU could alleviate marrow toxicity ...

journal_title：Cancer

authors： Soma M,Shoin K,Yamashita J

更新日期：1993-01-15 00:00:00

abstract：:A 20-year-old man with previously treated lymphoblastic lymphoma, a known T-cell disorder, developed progressive disease despite intensive combination chemotherapy with doxorubicin, vincristine, and prednisone. He was subsequently treated with a 21-day course of intravenous antithymocyte globulin at a dose of approxim...

journal_title：Cancer

authors： Wong KK Jr,Sweet DL,Variakojis D

更新日期：1982-07-01 00:00:00

abstract：BACKGROUND:A growing body of research has demonstrated that individuals who live in neighborhoods with more severe socioeconomic deprivation may have higher risks for colorectal cancer (CRC). However, previous studies have examined neighborhood socioeconomic status (SES) at only 1 point in time, and it is unclear wheth...

journal_title：Cancer

authors： Zhang D,Matthews CE,Powell-Wiley TM,Xiao Q

更新日期：2019-02-15 00:00:00

abstract：:The DNA sequences around codons 12, 13, and 61 of the ras gene were analyzed by polymerase chain reaction and direct sequencing in 18 intrahepatic cholangiocarcinomas. The ras gene mutations were found in 9 of 18 (50%): 6 in K-ras codon 12, 1 in K-ras codon 13, 1 in K-ras codon 61, and 1 in N-ras codon 12. The inciden...

journal_title：Cancer

authors： Tada M,Omata M,Ohto M

更新日期：1992-03-01 00:00:00

abstract：:A rare case of malignant fibrous histiocytoma of the aorta is reported. Review of the literature revealed that primary tumors of the aorta are exclusively mesenchymal tumors that almost invariably pursue a fatal course. ...

journal_title：Cancer

authors： Chen KT

更新日期：1981-08-01 00:00:00

abstract：BACKGROUND:In many areas of health care, whether patients receive specific medical interventions often is influenced heavily by the local availability of resources for delivering those services. However, relations between resource availability and utilization are relatively unexplored in cancer care, including perioper...

journal_title：Cancer

authors： Wong SL,Wei Y,Birkmeyer JD

更新日期：2007-02-15 00:00:00

abstract：:Epithelioid sarcoma is an uncommon tumor characterized by its appearance in the distal extremities (especially the forearm, wrist, and ankle), the tendency to recur locally, and high probability of spread to regional lymph nodes. Most patients have been treated surgically, and the potential role of radiation therapy a...

journal_title：Cancer

authors： Shimm DS,Suit HD

更新日期：1983-09-15 00:00:00

abstract：:Six patients with lymphomatoid granulomatosis were studied. Two patients had eye involvement, a rare manifestation of this disease. Both had complete disappearance of disease in this area after radiation therapy. One patient presented with an autoimmune hemolytic anemia, which remitted completely with chemotherapy. Th...

journal_title：Cancer

authors： Sordillo PP,Epremian B,Koziner B,Lacher M,Lieberman P

更新日期：1982-05-15 00:00:00

abstract：:The ultrastructure of three cases of osteoblastoma is described. The osteoblasts resemble normal osteoblasts with a few exceptions: irregular, indented nuclei, and occasional mitochondria with curved cristae and electron-lucent areas. The osteocytes and osteoclasts basically resemble their normal counterparts. There a...

journal_title：Cancer

authors： Steiner GC

更新日期：1977-05-01 00:00:00

abstract：BACKGROUND:Multiple intraesophageal primary cancer and upper aerodigestive tract (UADT) cancer associated with esophageal cancer are common diseases, especially in heavy drinkers. They are often explained by the concept of field cancerization, which suggests a similar etiology. However, little is known about the nature...

journal_title：Cancer

authors： Yokoyama A,Muramatsu T,Ohmori T,Makuuchi H,Higuchi S,Matsushita S,Yoshino K,Maruyama K,Nakano M,Ishii H

更新日期：1996-05-15 00:00:00

abstract：BACKGROUND:To the authors' knowledge, the potential prognostic value of DNA ploidy in vulvar melanoma has not been evaluated in previous series. METHODS:Clinical data and follow-up information were retrieved from the hospital records of 75 patients treated from 1956 to 1987. Histopathologic specimens were reviewed for...

journal_title：Cancer

authors： Scheistrøen M,Tropé C,Koern J,Pettersen EO,Abeler VM,Kristensen GB

更新日期：1995-01-01 00:00:00

abstract：:A 28-year-old man with evidence of feminization was demonstrated after 4 years of investigation to have a estrogen-secreting interstitial cell tumor. Such feminizing neoplasms are uncommon, only 37 having been described. They are usually benign and are characterized by gynecomastia, a testicular mass and, with lesser ...

journal_title：Cancer

authors： Gabrilove JL,Nicolis GL,Mitty HA,Sohval AR

更新日期：1975-04-01 00:00:00

abstract：:Hepatoid adenocarcinomas of the stomach are gastric carcinomas with both adenocarcinomatous and hepatocellular differentiations. They usually produce large amounts of alpha-fetoprotein (AFP) with a Concanavalin A-binding property of hepatic type. In this study, these carcinomas occurred in older persons, with the antr...

journal_title：Cancer

authors： Ishikura H,Kirimoto K,Shamoto M,Miyamoto Y,Yamagiwa H,Itoh T,Aizawa M

更新日期：1986-07-01 00:00:00

abstract：BACKGROUND:Bortezomib has preclinical and clinical in B-cell lymphomas, both alone and in combination with other agents. A phase 1 evaluation was conducted of bortezomib with rituximab plus cyclophosphamide, doxorubicin, vincristine, and prednisone (R-CHOP) in patients with untreated diffuse large B-cell lymphoma (DLBC...

journal_title：Cancer

authors： Furman RR,Martin P,Ruan J,Cheung YK,Vose JM,LaCasce AS,Elstrom R,Coleman M,Leonard JP

更新日期：2010-12-01 00:00:00

abstract：BACKGROUND:Endometrial carcinoma is one of the most frequent malignancies in the female genital tract, and its incidence has been increasing in Japan. Histologic grade is an important factor for organizing treatment strategies, including hormone therapy, and for predicting the prognosis of the patient. The objective of...

journal_title：Cancer

authors： Nishimura Y,Watanabe J,Jobo T,Hattori M,Arai T,Kuramoto H

更新日期：2005-02-25 00:00:00

abstract：:This study defines, by morphometric analysis, criteria for the diagnosis of ovarian dysplasia. Areas of surface epithelium, adjacent to Stage I ovarian serous papillary adenocarcinoma, were diagnosed as dysplastic and evaluated for architectural and cytologic changes by means of two specially designed interactive morp...

journal_title：Cancer

authors： Deligdisch L,Gil J

更新日期：1989-02-15 00:00:00

abstract：BACKGROUND:The Women's Health Initiative randomized clinical trial reported that menopausal hormone therapy increases lung cancer mortality risk. If this is true, use of anti-estrogens should be associated with decreased lung cancer mortality risk. The authors compared lung cancer incidence and mortality among breast c...

journal_title：Cancer

authors： Bouchardy C,Benhamou S,Schaffar R,Verkooijen HM,Fioretta G,Schubert H,Vinh-Hung V,Soria JC,Vlastos G,Rapiti E

更新日期：2011-03-15 00:00:00