Observations on growth rate of breast carcinomas and its possible implications for lead time.

abstract：BACKGROUND:An association between laryngopharyngeal reflux (LPR) and laryngeal carcinoma has been suggested, but remains unproven. The current pilot study was performed to determine the incidence of LPR among patients with early laryngeal carcinomas or dysplasia and to examine the associations between levels of LPR and...

journal_title：Cancer

authors： Lewin JS,Gillenwater AM,Garrett JD,Bishop-Leone JK,Nguyen DD,Callender DL,Ayers GD,Myers JN

更新日期：2003-02-15 00:00:00

abstract：LAY SUMMARY:During the coronavirus disease 2019 (COVID-19) pandemic, cancer screening decreased precipitously; home screening for colorectal cancer diminished less than that for colonoscopy and breast and cervical cancer screening. The authors have highlighted approaches for home cancer screening in addition to telemed...

journal_title：Cancer

authors： Gorin SNS,Jimbo M,Heizelman R,Harmes KM,Harper DM

更新日期：2021-02-15 00:00:00

abstract：BACKGROUND:Because carcinomas of unknown primary origin are highly malignant tumors with a bad prognosis (median survival, 6-12 months) and no current optimal therapy, the authors designed a prospective dose-dense chemotherapy regimen with the objective of improving the results observed in patients who receive conventi...

journal_title：Cancer

authors： Culine S,Fabbro M,Ychou M,Romieu G,Cupissol D,Pinguet F

更新日期：2002-02-01 00:00:00

abstract：BACKGROUND AND METHODS:The antiemetic activity of ondansetron (Zofran, Glaxo Pharmaceuticals, Research Triangle Park, NC) was evaluated in 25 patients with recurrent melanoma who were treated sequentially with dacarbazine (DTIC), vinblastine, and cisplatin. The antiemetic regimen included ondansetron alone in 11 patien...

journal_title：Cancer

authors： Legha SS,Hodges C,Ring S

更新日期：1992-10-01 00:00:00

abstract：BACKGROUND:The current study examines 1) the sensitivity of detection and 2) sampling and screening/diagnostic error in the cytologic diagnosis of adenocarcinoma in situ (AIS) of the cervix. The data were taken from public and private sector screening laboratories reporting 25,000 and 80,000 smears, respectively, each ...

journal_title：Cancer

authors： Schoolland M,Segal A,Allpress S,Miranda A,Frost FA,Sterrett GF

更新日期：2002-12-25 00:00:00

abstract：:To investigate the utility of thallium 201 (Tl-201) thyroid scintigraphy for the detection of thyroid malignancies, early and delayed Tl-201 scintigraphy was done in 70 consecutive patients with a clinically solitary cold (Iodine 123 [I-123]) nodule. Early Tl-201 scintigraphy had a sensitivity of 100% and a specificit...

journal_title：Cancer

authors： Bleichrodt RP,Vermey A,Piers DA,de Langen ZJ

更新日期：1987-12-01 00:00:00

abstract：BACKGROUND:For patients with stage III through IVB head and neck squamous cell carcinoma (HNSCC), concurrent high-dose cisplatin plus radiation therapy is a widely accepted standard of care. HNSCC tumors that express high levels of vascular endothelial growth factor have been associated with a worse prognosis, and beva...

journal_title：Cancer

authors： Fury MG,Lee NY,Sherman E,Lisa D,Kelly K,Lipson B,Carlson D,Stambuk H,Haque S,Shen R,Kraus D,Shah J,Pfister DG

更新日期：2012-10-15 00:00:00

abstract：:Irreversible and progressive renal parenchymal damage and functional impairment occurred in the majority of patients receiving at least six courses (200 mg/m2 of BCNU and/or methyl CCNU at eight-week intervals) of nitrosoureas for therapy of malignant brain tumors. Seventeen of 18 patients who received at least six co...

journal_title：Cancer

authors： Schacht RG,Feiner HD,Gallo GR,Lieberman A,Baldwin DS

更新日期：1981-09-15 00:00:00

abstract：BACKGROUND:Lobular neoplasia (LN), also known as lobular carcinoma in situ, is an incidental histologic finding in tissue removed at breast surgery. Patients with LN are known to be predisposed to develop invasive or intraductal carcinoma (CA). This study investigates factors that influence the cancer risk in LN patien...

journal_title：Cancer

authors： Bodian CA,Perzin KH,Lattes R

更新日期：1996-09-01 00:00:00

abstract：BACKGROUND:Assessment of the responses of osteosarcoma patients to preoperative chemotherapy is of clinical importance. The purpose of this study was to estimate the accuracy of angiography and thallium-201 scintigraphy, compared with histology, in assessing the responses of patients with osteosarcoma to preoperative c...

journal_title：Cancer

authors： Kunisada T,Ozaki T,Kawai A,Sugihara S,Taguchi K,Inoue H

更新日期：1999-09-15 00:00:00

abstract：BACKGROUND:Combined transperineal prostate brachytherapy and external beam radiation therapy (EBRT) is widely used for treatment of prostate cancer. Long-term efficacy and toxicity results of a multicenter phase 2 trial assessing combination of EBRT and transperineal prostate brachytherapy boost with androgen deprivati...

journal_title：Cancer

authors： Hurwitz MD,Halabi S,Archer L,McGinnis LS,Kuettel MR,DiBiase SJ,Small EJ

更新日期：2011-12-15 00:00:00

abstract：:The acquisition by tumor cells of the ability to metastasize is the critical event in the clinical course of most human neoplastic disease. While metastasis plays a pivotal role in the ultimate success of failure of therapy, it is in fact a result of a more insidious malignant process termed tumor progression. It is t...

journal_title：Cancer

authors： Frost P,Fidler IJ

更新日期：1986-07-15 00:00:00

abstract：:Retinitis pigmentosa, a hereditary disease characterized by progressive retinal degeneration and blindness, has been associated with numerous diseases. We report the first association between retinitis pigmentosa and colon cancer in 3 of 53 hospitalized patients with retinitis pigmentosa at the Massachusetts General H...

journal_title：Cancer

authors： Winzelberg GG,Greenstein R,Ferrucci JT Jr

更新日期：1980-06-01 00:00:00

abstract：BACKGROUND:Cytology and core-needle biopsies are not always sufficient to exclude malignancy in benign breast lesions (BBL) that are at risk of developing cancer, and open biopsy often is mandatory. In screening programs, open biopsies performed for lesions that are at risk of developing malignancy are considered benig...

journal_title：Cancer

authors： Manfrin E,Mariotto R,Remo A,Reghellin D,Falsirollo F,Dalfior D,Bricolo P,Piazzola E,Bonetti F

更新日期：2009-02-01 00:00:00

abstract：BACKGROUND:Although axillary lymph node metastasis is one of the most important prognostic determinants of breast carcinoma prognoses, the reasons why tumors vary in their capability to produce for axillary metastases remain unclear. METHODS:The authors used data from the nationwide Patient Care Evaluation (PCE) surve...

journal_title：Cancer

authors： Gann PH,Colilla SA,Gapstur SM,Winchester DJ,Winchester DP

更新日期：1999-10-15 00:00:00

abstract：:The use of molecular techniques in cytopathology has become an accepted and billable practice for certain applications. Other applications still are in the developmental or experimental stages but may soon be clinically useful. The current study provides a review of these techniques including molecular detection of cl...

journal_title：Cancer

authors： Rimm DL

更新日期：2000-02-25 00:00:00

abstract：BACKGROUND:Evidence of racial disparities in the receipt of postmastectomy breast reconstruction is well documented. The objective of this study was to describe trends in racial disparities overall and by reconstructive technique. METHODS:The American College of Surgeons National Surgical Quality Improvement Program d...

journal_title：Cancer

authors： Epstein S,Tran BN,Cohen JB,Lin SJ,Singhal D,Lee BT

更新日期：2018-07-01 00:00:00

abstract：:Fifty-nine colorectal carcinomas of patients with verified cancer family syndrome (CFS) were analyzed for DNA ploidy using flow cytometry. Sixty-eight percent of the tumors were diploid, and 32% were aneuploid. The aneuploid tumors had a median DNA index of 1.24 (range, 1.12-1.97). In 90% of all tumors the DNA index w...

journal_title：Cancer

authors： Kouri M,Laasonen A,Mecklin JP,Järvinen H,Franssila K,Pyrhönen S

更新日期：1990-04-15 00:00:00

abstract：BACKGROUND:Gene expression profiling (GEP) has been rapidly adopted for early breast cancer and can aid in chemotherapy decision making. Study results regarding racial disparities in testing are conflicting, and may reflect different care settings. To the authors' knowledge, data regarding the influence of provider fac...

journal_title：Cancer

authors： Reeder-Hayes KE,Wheeler SB,Baggett CD,Zhou X,Meng K,Roberts MC,Carey LA,Meyer AM

更新日期：2018-04-15 00:00:00

abstract：:The morphologic features, phenotype, and functions of OKM1+ leukemic T-cells were studied. The leukemic T-cells in two patients with chronic lymphocytic leukemia (CLL) had specific features of large granular lymphocytes (LGL), and those in two patients with acute lymphocytic leukemia (ALL) had L2 morphologic character...

journal_title：Cancer

authors： Tagawa S,Taniguchi N,Tokumine Y,Tamaki T,Konishi I,Kanayama Y,Inoue R,Machii T,Kitani T

更新日期：1986-04-15 00:00:00

abstract：:The ability to noninvasively discriminate the most common types of renal cell carcinoma (RCC) based on their magnetic resonance imaging (MRI) appearances or their magnetic resonance phenotypes is achievable. Intracellular lipids, a histologic characteristic of the clear cell RCC, can be identified on chemical shift MR...

journal_title：Cancer

authors： Pedrosa I,Alsop DC,Rofsky NM

更新日期：2009-05-15 00:00:00

abstract：:The presence of receptors for estrogen, glucocorticoid and progesterone was determined in the cytosol of two breast angiosarcomas. Estrogen and glucocorticoid receptors were present in both of them. Progesterone receptors were present in one of the two tumors assayed. Occupied nuclear estrogen receptors have been foun...

journal_title：Cancer

authors： Brentani MM,Pacheco MM,Oshima CT,Nagai MA,Lemos LB,Góes JC

更新日期：1983-06-01 00:00:00

abstract：BACKGROUND:The observed seasonal and geographic variations in the incidence of immunoproliferative small intestinal disease (IPSID) suggest that environmental factors contribute to its pathogenesis. One such environmental factor, the Epstein-Barr virus (EBV), has been associated with other B-cell lymphoproliferative di...

journal_title：Cancer

authors： Baddoura FK,Unger ER,Mufarrij A,Nassar VH,Zaki SR

更新日期：1994-09-15 00:00:00

abstract：BACKGROUND:In the current study, the authors attempted to describe the incidence, most common sites, and mortality of second primary malignancies among survivors of common cancers. METHODS:The authors identified patients aged ≥18 years who were diagnosed with a primary malignancy from the 10 most common cancer sites (...

journal_title：Cancer

authors： Donin N,Filson C,Drakaki A,Tan HJ,Castillo A,Kwan L,Litwin M,Chamie K

更新日期：2016-10-01 00:00:00

abstract：BACKGROUND:Some patients with chronic myeloid leukemia (CML) have a history of previous malignancies. To the authors' knowledge, outcomes for CML diagnosed in these patients have not been well described. The current study was conducted to determine the outcome of patients with CML and a history of prior malignancies. ...

journal_title：Cancer

authors： Koller PB,Kantarjian HM,Nogueras-Gonzalez GM,Jabbour E,Verstovsek S,Borthakur G,Estrov Z,Wierda WG,Garcia-Manero G,Ferrajoli A,Ravandi F,O'Brien SM,Cortes JE

更新日期：2017-02-15 00:00:00

abstract：:The therapeutic effect of prednimustine was studied in 35 patients with advanced breast cancer resistant to previous cytotoxic and/or endocrine therapy. Response (PR + CR) was obtained in 14 patients (40%) of a median duration of five months. Among the 14 responding patients, 10 were resistant to previous endocrine th...

journal_title：Cancer

authors： Mouridsen HT,Kristensen D,Nielsen JH,Dombernowsky P

更新日期：1980-07-15 00:00:00

abstract：BACKGROUND:This study explores whether externalizing religious and spiritual beliefs is associated with advanced-stage colon cancer at initial oncology presentation and whether this association is stronger for blacks than for whites. METHODS:Patients who had newly diagnosed, invasive colon cancer were recruited at 9 s...

journal_title：Cancer

authors： Polite BN,Cipriano-Steffens TM,Hlubocky FJ,Jean-Pierre P,Cheng Y,Brewer KC,Rauscher GH,Fitchett GA

更新日期：2018-06-15 00:00:00

abstract：BACKGROUND:: Although patients with chronic pancreatitis (CP) have an increased risk of pancreatic cancer (PanCa), the timely detection of PanCa often is difficult, because the symptoms of CP and PanCa are very similar. Moreover, secondary inflammation may be identified in PanCa, further complicating diagnosis. To impr...

journal_title：Cancer

authors： Liggett T,Melnikov A,Yi QL,Replogle C,Brand R,Kaul K,Talamonti M,Abrams RA,Levenson V

更新日期：2010-04-01 00:00:00

abstract：BACKGROUND:The development of malignancies in recipients of a cardiothoracic transplant (CTT)--that is, heart, lung, or heart and lung recipients-is of concern. Cutaneous and lymphoproliferative malignancies comprise the two major groups of malignancies encountered. A small subgroup of patients will develop potentially...

journal_title：Cancer

authors： Veness MJ,Quinn DI,Ong CS,Keogh AM,Macdonald PS,Cooper SG,Morgan GW

更新日期：1999-04-15 00:00:00

abstract：BACKGROUND:The goal of the current study was to assess the toxicity, safety, and efficacy of pentostatin in patients with T-cell lymphoid malignancies. METHODS:Patients were eligible if they had biopsy-proven T-cell lymphoma or leukemia and failure to respond to previous therapy or an expected complete response rate t...

journal_title：Cancer

authors： Tsimberidou AM,Giles F,Duvic M,Fayad L,Kurzrock R

更新日期：2004-01-15 00:00:00