Abstract:
:The therapeutic effect of prednimustine was studied in 35 patients with advanced breast cancer resistant to previous cytotoxic and/or endocrine therapy. Response (PR + CR) was obtained in 14 patients (40%) of a median duration of five months. Among the 14 responding patients, 10 were resistant to previous endocrine therapy and chemotherapy, in all cases including alkylating agents, and 4 were resistant to previous endocrine therapy. Hematologic toxicity was rather pronounced, but other toxicities were only moderate.
journal_name
Cancerjournal_title
Cancerauthors
Mouridsen HT,Kristensen D,Nielsen JH,Dombernowsky Pdoi
10.1002/1097-0142(19800715)46:2<253::aid-cncr28204subject
Has Abstractpub_date
1980-07-15 00:00:00pages
253-5issue
2eissn
0008-543Xissn
1097-0142journal_volume
46pub_type
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