Abstract:
:To investigate the utility of thallium 201 (Tl-201) thyroid scintigraphy for the detection of thyroid malignancies, early and delayed Tl-201 scintigraphy was done in 70 consecutive patients with a clinically solitary cold (Iodine 123 [I-123]) nodule. Early Tl-201 scintigraphy had a sensitivity of 100% and a specificity of 7% in predicting malignancy. With a combination of early and delayed Tl-201 scintigraphy, sensitivity ranged from 17 to 25% and specificity from 95 to 100%. Early and and delayed Tl-201 scintigraphy are only of limited value for the detection of thyroid cancer.
journal_name
Cancerjournal_title
Cancerauthors
Bleichrodt RP,Vermey A,Piers DA,de Langen ZJdoi
10.1002/1097-0142(19871201)60:11<2621::aid-cncr282subject
Has Abstractpub_date
1987-12-01 00:00:00pages
2621-3issue
11eissn
0008-543Xissn
1097-0142journal_volume
60pub_type
杂志文章相关文献
CANCER文献大全abstract:BACKGROUND:Complementary medicine has become an important aspect of palliative cancer care. This overview is primarily aimed at providing guidance to clinicians regarding some commonly used complementary therapies. METHODS:Several complementary therapies were identified as particularly relevant to palliative cancer ca...
journal_title:Cancer
pub_type: 杂志文章,评审
doi:10.1002/1097-0142(20010601)91:11<2181::aid-cncr124
更新日期:2001-06-01 00:00:00
abstract:BACKGROUND:The objective of this study was to assess the efficacy of adding chronic, intermittent, low-dose vinorelbine to gefitinib treatment for patients who had adenocarcinoma of the lung who failed>or=2 regimens of chemotherapy. METHODS:Patients were randomized into 2 arms: Oral gefitinib 250 mg daily (the G arm) ...
journal_title:Cancer
pub_type: 杂志文章,随机对照试验
doi:10.1002/cncr.22616
更新日期:2007-05-01 00:00:00
abstract::Forty-six cases of resected lung cancer, including 20 cases at Stages I and II and 26 cases at Stage III (N2), were subdivided into two groups: a good prognosis group with a longer survival period and a poor prognosis group in which the patients died earlier of the cancer. From paraffin-embedded lymph node tissues of ...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19910301)67:5<1370::aid-cncr2820
更新日期:1991-03-01 00:00:00
abstract:BACKGROUND:It is frequently difficult to establish histologically whether a parathyroid tumor is a parathyroid carcinoma, parathyromatosis, or an atypical adenoma. The authors asked whether these tumors have a distinctive molecular profile, whether benign tumors could be distinguished from malignant tumors, and whether...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.24037
更新日期:2009-01-15 00:00:00
abstract::Two female patients with desmoid tumors (aggressive fibromatosis) showed tumor regression after endocrine therapy. In one patient, tumor response to tamoxifen has been maintained over several years of treatment. In the second patient, who had inoperable mesenteric fibromatosis, the tumor progressed on tamoxifen but re...
journal_title:Cancer
pub_type: 杂志文章,评审
doi:10.1002/1097-0142(19910915)68:6<1384::aid-cncr2820
更新日期:1991-09-15 00:00:00
abstract::Seventy-seven patients with relapsed or refractory acute leukemia and three with acute blastic chronic myeloid leukemia (CML) were treated in an open Phase II study using mitoxantrone 12 mg/m2 intravenously daily X 5 days. Complete remission (CR) was achieved in 32 of 80 (40%), including 23/45 (52%) with relapsed acut...
journal_title:Cancer
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1002/1097-0142(19900801)66:3<418::aid-cncr28206
更新日期:1990-08-01 00:00:00
abstract:BACKGROUND:The purpose of this study was to assess prostate carcinoma detection and discrimination of benign from malignant prostate tissue with contrast-enhanced ultrasonography. METHODS:In all, 301 subjects referred for prostate biopsy were evaluated with contrast-enhanced sonography using continuous harmonic imagin...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.21440
更新日期:2005-12-01 00:00:00
abstract::Vitamin B6 is involved in many biological processes of potential relevance to carcinogenesis and tumor growth, including DNA synthesis and maintenance of immunocompetence, yet very little information exists on B6 nutritional status in childhood leukemia. Using a radioenzymatic assay, the authors measured plasma pyrido...
journal_title:Cancer
pub_type: 杂志文章,评审
doi:10.1002/1097-0142(19901201)66:11<2421::aid-cncr282
更新日期:1990-12-01 00:00:00
abstract:BACKGROUND:Smoldering multiple myeloma (SMM) presents a high risk of progression to symptomatic MM (sy-MM). Herein, we analyzed some predictors of development of sy-MM. In 144 patients with SMM, we also compared the risk of progression predicted by bone marrow plasma cell (BMPC) involvement on the bone marrow biopsy (B...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.27657
更新日期:2012-11-15 00:00:00
abstract:BACKGROUND:Current prognostic information in ovarian cancer is based on tumor stage, tumor grade, and postoperative tumor size. Reliable molecular prognostic markers are scarce. In this article, the authors describe epigenetic events in a frequently deleted region on chromosome 8p22 that influence the expression of tum...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.27850
更新日期:2013-03-01 00:00:00
abstract::The results of nine US multicenter, sequential crossover, dose titration studies of controlled-release oral morphine (MS Contin 30 mg tablets [MSC], Purdue Frederick, Norwalk, CT) are reviewed in Part I. The studies demonstrated the prolonged analgesic efficacy of the preparation in the treatment of patients with mode...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19890601)63:11<2348::aid-cncr282
更新日期:1989-06-01 00:00:00
abstract::All patients with a diagnosis of cutaneous malignant melanoma (CMM) in Western Australia from 1980 to 1981 were observed for up to 6 years to determine vital status and to detect the development of local recurrences of the primary lesion. Approximately 35% of all patients had their tumors excised with surgical margins...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19920115)69:2<421::aid-cncr28206
更新日期:1992-01-15 00:00:00
abstract:BACKGROUND:This study was conducted to determine the efficacy and safety of irinotecan (CPT-11) as second-line therapy in patients with advanced cervical carcinoma. METHODS:Sixteen patients with platinum-resistant squamous cell carcinoma were treated with CPT-11 as second-line therapy. CPT-11 was administered in repea...
journal_title:Cancer
pub_type: 临床试验,杂志文章
doi:10.1002/(sici)1097-0142(19980115)82:2<334::aid-cnc
更新日期:1998-01-15 00:00:00
abstract::Earlier literature suggests a high incidence of multicentricity and bilaterality, with an overall poor prognosis, in patients with invasive lobular carcinoma of the breast. Consequently, there is considerable disagreement regarding appropriate local management of this disease. To determine the influence of invasive lo...
journal_title:Cancer
pub_type: 杂志文章,评审
doi:10.1002/1097-0142(19920601)69:11<2789::aid-cncr282
更新日期:1992-06-01 00:00:00
abstract::The efficacy of mitoxantrone in combination with vinblastine was assessed in 156 patients with metastatic breast cancer who had been treated previously with one or multiple chemotherapeutic regimens. Mitoxantrone was given by random assignment, either as a 10 mg/m2 single intravenous dose or in five consecutive daily ...
journal_title:Cancer
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1002/1097-0142(19871015)60:8<1724::aid-cncr2820
更新日期:1987-10-15 00:00:00
abstract::A case of primary hemangiosarcoma of the spleen in a 48-year-old woman is presented. Twenty-eight months after splenectomy the patient developed a severe anemia of the microangiopathic type, thrombocytopenia, and a leukoerythroblastic peripheral blood picture. In contrast to x-ray and conventional 99mTc-methylene-diph...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19840415)53:8<1682::aid-cncr2820
更新日期:1984-04-15 00:00:00
abstract:BACKGROUND:The authors developed fluoroscopic real-time tumor-tracking radiation therapy (RTRT) by insertion of a gold marker using bronchofiberscopy to reduce uncertainties in organ motion and set-up error in external radiotherapy for moving tumors. The purpose of the current study was to evaluate RTRT's feasibility i...
journal_title:Cancer
pub_type: 临床试验,杂志文章
doi:10.1002/cncr.10856
更新日期:2002-10-15 00:00:00
abstract::Sixteen cases of clear cell adenocarcinoma of the cervix and vagina in young women were studied by electron microscopy and the observations were compared with the light microscopic appearance. Ultrastructurally, the neoplastic cells were found to be of the same basic type, regardless of whether light microscopy disclo...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19800401)45:7<1615::aid-cncr2820
更新日期:1980-04-01 00:00:00
abstract:BACKGROUND:Pediatric renal cell carcinoma (RCC) is clinically distinct from adult RCC. Characterization of the unique biological and clinical features of pediatric RCC are required. METHODS:A retrospective review and biological analysis of all RCC cases presenting to Cincinnati Children's Hospital Medical Center (CCHM...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.23331
更新日期:2008-04-01 00:00:00
abstract:BACKGROUND:Nonionizing radiation, such as radiofrequency field and near infrared laser, induces thermal cytotoxicity in cancer cells treated with gold nanoparticles. Quantum dots are fluorescent semiconducting nanoparticles that were hypothesized to induce similar injury after radiofrequency field irradiation. METHODS...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.25135
更新日期:2010-07-01 00:00:00
abstract:BACKGROUND:The current analysis of outcomes in a large series of adult patients with intracranial ependymal tumors contributes to the characterization of the primary prognostic factors and to the therapeutic management of this rare disease, for which limited information is available in the literature. METHODS:The auth...
journal_title:Cancer
pub_type: 杂志文章,多中心研究
doi:10.1002/cncr.20074
更新日期:2004-03-15 00:00:00
abstract:BACKGROUND:Recently, the authors identified molecular signatures and pathways associated with nonsmall cell lung carcinoma histology and lung development. They hypothesized that genetic classifiers of histology would provide insight into lung tumorigenesis and would be associated with clinical outcome when evaluated in...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.20542
更新日期:2004-10-01 00:00:00
abstract::The occurrence and staining patterns of Concanavalin A (Con A) binding histiocytes were studied in diagnostic lymph node specimens of 133 patients with Hodgkin's disease. Varying numbers of Con A binding histiocytes were present in all tumors. Two distinct cytoplasmic staining patterns of the Con A binding histiocytes...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19830715)52:2<252::aid-cncr28205
更新日期:1983-07-15 00:00:00
abstract::In recent years a major focus in the delivery of cancer prevention services has been on the actions of physicians in ambulatory care practice. Whereas delivery of these services has increased markedly, it is likely that physician actions overall are not producing expected measurable benefits to whole populations. The ...
journal_title:Cancer
pub_type: 杂志文章,评审
doi:10.1002/1097-0142(19940815)74:4+<1418::aid-cncr282
更新日期:1994-08-15 00:00:00
abstract:BACKGROUND:National Cancer Institute of Canada Clinical Trials Group PA.3 (NCIC CTG PA.3) was a phase 3 study (n = 569) that demonstrated benefits for overall survival and progression-free survival with the addition of the epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) erlotinib to gemcitabine ...
journal_title:Cancer
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1002/cncr.25393
更新日期:2010-12-15 00:00:00
abstract:BACKGROUND:In recent years numerous reports have discussed the relationship between the human leukocyte antigen and lung cancer. However, the genetic background of lung cancer has not yet been precisely clarified. METHODS:To investigate the genetic background of lung cancer, the human leukocyte antigens in 159 normal ...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19940215)73:4<1184::aid-cncr2820
更新日期:1994-02-15 00:00:00
abstract::Randomized breast cancer screening trials are helpful in establishing evidence of benefit when they yield statistically significant results. The results of individual randomized screening trials can vary greatly depending on the quality of the images, the frequency of screening, compliance, contamination, sample size,...
journal_title:Cancer
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1002/cncr.2820741314
更新日期:1994-07-01 00:00:00
abstract::We detected cytoplasmic estrogen receptors (ER) in only 4 of 34 (12%) patients with malignant melanoma. The titers as assayed by the dextran-coated charcoal method were 3, 3, 4, and 5 fmol/mg, respectively. Our data indicate that the incidence of melanoma with detectable ER is low, which suggests that any potential cl...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19801015)46:8<1785::aid-cncr2820
更新日期:1980-10-15 00:00:00
abstract:BACKGROUND:In this report, the authors describe their collective experience with melphalan-based autotransplants since the inception of their program at the University of Arkansas for Medical Sciences in 1989. METHODS:The authors evaluated the clinical outcomes of 3077 successive patients with multiple myeloma (MM) wh...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.23327
更新日期:2008-04-15 00:00:00
abstract::The authors report the accuracy of mammographically guided fine-needle aspiration (FNA) for the diagnosis of nonpalpable breast lesions in a series of 71 patients. Each mammographically guided FNA was immediately followed by hookwire localization and open biopsy. Seven malignancies were identified cytologically, but t...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19911101)68:9<2007::aid-cncr2820
更新日期:1991-11-01 00:00:00