Methylation status of TUSC3 is a prognostic factor in ovarian cancer.

abstract：:The case of a 49-year-old man with the diagnosis of angioimmunoblastic lymphadenopathy is reported. The patient survived a stormy clinical course. The corticosteroids improved dramatically the clinical picture although the patient developed a staphylococcal septicemia. Before treatment immunological studies were done ...

journal_title：Cancer

authors： Kosmidis PA,Axelrod AR,Palacas C,Stahl M

更新日期：1978-08-01 00:00:00

abstract：:Preclinical and clinical studies suggest interferons and interferon inducers have antitumor activity for breast carcinoma. Observations include inhibition of growth of freshly derived and continuously passaged breast carcinoma cells in vitro, decreased tumor size and increased survival in spontaneous mouse mammary car...

journal_title：Cancer

authors： Borden EC,Balkwill FR

更新日期：1984-02-01 00:00:00

abstract：BACKGROUND:LAMP3 is a newly described hypoxia regulated gene of potential interest in hypoxia-induced therapy resistance and metastasis. The prognostic value of LAMP3 in breast cancer was investigated. METHODS:Expression levels of LAMP3 in breast cancer cell lines and patient tissues were determined by real-time polym...

journal_title：Cancer

authors： Nagelkerke A,Mujcic H,Bussink J,Wouters BG,van Laarhoven HW,Sweep FC,Span PN

更新日期：2011-08-15 00:00:00

abstract：BACKGROUND:Angiogenesis in individuals with various solid tumors has provided useful information on tumor progression and prognosis, and many examples of mast cell (MC) accumulation coupled with angiogenesis can be found in the literature. METHODS:Utilizing monoclonal antibodies for tryptase that are specific markers ...

journal_title：Cancer

authors： Takanami I,Takeuchi K,Naruke M

更新日期：2000-06-15 00:00:00

abstract：:Five hundred and sixty-nine patients with breast cancer presenting for treatment at a community hospital were studied. The results showed no significant change in tumor size at presentation or reported patient delay over a 12-year span. This was in spite of considerable national discussion and increasing public concer...

journal_title：Cancer

authors： Buttlar CA,Templeton AC

更新日期：1983-05-01 00:00:00

abstract：:To evaluate the role of chemotherapy in local control of primary breast cancer, the incidence of local failure was evaluated in 768 patients treated with surgery and adjuvant, combination chemotherapy that contained fluorouracil, doxorubicin, and cyclophosphamide (FAC) at our institute between 1974 and 1982. Of these ...

journal_title：Cancer

authors： Buzdar AU,McNeese MD,Hortobagyi GN,Smith TL,Kau S,Fraschini G,Hug V,Ellerbroek N,Holmes FA,Ames F

更新日期：1990-02-01 00:00:00

abstract：:The National Comprehensive Cancer Network (NCCN) describes the presence of extracapsular spread and/or positive margins in oropharynx cancer (OPC) as an indication for the addition of chemotherapy to postoperative radiation. The guideline's category 1 consensus is based on what they term high-level evidence. For this ...

journal_title：Cancer

authors： Sinha P,Piccirillo JF,Kallogjeri D,Spitznagel EL,Haughey BH

更新日期：2015-06-01 00:00:00

abstract：BACKGROUND:The activation of the clotting-fibrinolytic system in cancer patients is common and represents an unfavorable clinical sign. D-dimer (DD) is a sensitive marker of fibrinolysis. METHODS:The current study comprised 826 new lung carcinoma patients seen consecutively in a single institution over a 10-year perio...

journal_title：Cancer

authors： Buccheri G,Torchio P,Ferrigno D

更新日期：2003-06-15 00:00:00

abstract：BACKGROUND:Radiofrequency (RF)-induced tissue coagulation represents a new approach for the thermal destruction of tumors within the liver. The purpose of the current study was to 1) assess technique safety; 2) determine the extent and evolution of induced cellular damage; and 3) correlate the observed pathologic effec...

journal_title：Cancer

authors： Goldberg SN,Gazelle GS,Compton CC,Mueller PR,Tanabe KK

更新日期：2000-06-01 00:00:00

abstract：:Quality assurance for the management of multicenter clinical trials requires timely patient and data accrual and consistency with design parameters. Data from central pathology review, treatment modality, and follow-up as well as trial end points direct the selection of appropriate compliance measures. To integrate th...

journal_title：Cancer

authors： Pollock BH

更新日期：1994-11-01 00:00:00

abstract：BACKGROUND:Micropapillary serous carcinoma (MPSC), a recently described entity, is an ovarian tumor with a distinctive histologic architecture that lacks a destructive infiltrative growth pattern and behaves like a low-grade neoplasm. The purpose of this study was to determine if specific cytomorphologic features were ...

journal_title：Cancer

authors： Alli PM,Ali SZ

更新日期：2002-06-25 00:00:00

abstract：BACKGROUND:Conditional survival is clinically useful, particularly for patients with malignant disease who have a poor prognosis. However, there are no published data on the conditional median survival of patients with advanced carcinoma on a population basis. METHODS:Data on 217,573 patients with breast, colorectal, ...

journal_title：Cancer

authors： Kato I,Severson RK,Schwartz AG

更新日期：2001-10-15 00:00:00

abstract：:During the period from September, 1976 to June, 1979, 70 patients with locoregional or extensive epidermoid carcinoma of the esophagus were treated with the two-drug combination of cisplatin and bleomycin (DB). For the 43 patients with locoregional disease (LRD), DB was used prior to surgery and/or radiation therapy; ...

journal_title：Cancer

authors： Coonley CJ,Bains M,Hilaris B,Chapman R,Kelsen DP

更新日期：1984-12-01 00:00:00

abstract：BACKGROUND:After the introduction of a mammography screening program, the incidence of late-stage breast cancer is expected to decrease. The objective of the current study was to evaluate variations in the total incidence of breast cancer and in the incidence of breast cancers with a pathologic tumor (pT) classificatio...

journal_title：Cancer

authors： Foca F,Mancini S,Bucchi L,Puliti D,Zappa M,Naldoni C,Falcini F,Gambino ML,Piffer S,Sanoja Gonzalez ME,Stracci F,Zorzi M,Paci E,IMPACT Working Group.

更新日期：2013-06-01 00:00:00

abstract：:Because we found it illogical to attempt measurement of nonmeasurable but visible tumors in patients with advanced lung cancer, we devised and used a separate set of response criteria for patients with evaluable, nonmeasurable tumors. Patients with evaluable disease who had obtained a tumor regression after therapy we...

journal_title：Cancer

authors： Eagan RT,Fleming TR,Schoonover V

更新日期：1979-09-01 00:00:00

abstract：BACKGROUND:Despite the widespread use of oxaliplatin-based regimens for colorectal and other gastrointestinal cancers, there is surprisingly little information regarding their empiric use for the treatment of carcinoma of unknown primary site (CUP). In the current study, the combination of oxaliplatin and capecitabine ...

journal_title：Cancer

authors： Hainsworth JD,Spigel DR,Burris HA 3rd,Shipley D,Farley C,Macias-Perez IM,Barton J,Greco FA

更新日期：2010-05-15 00:00:00

abstract：BACKGROUND:The purpose of this study was to determine the independent prognostic variables in a well documented subset of 216 patients with localized primary malignant fibrous histiocytomas (MFH). METHODS:Between the years 1980 and 1989, 216 patients with localized, primary (International Union Against Cancer [UICC]/A...

journal_title：Cancer

authors： Le Doussal V,Coindre JM,Leroux A,Hacene K,Terrier P,Bui NB,Bonichon F,Collin F,Mandard AM,Contesso G

更新日期：1996-05-01 00:00:00

abstract：BACKGROUND:Factors that could optimize the management of pediatric spinal cord astrocytoma remain unclear and controversial. METHODS:To determine the factors that influence the prognosis of pediatric patients with spinal cord astrocytomas, a series of 73 consecutive patients at 13 French treatment centers with histolo...

journal_title：Cancer

authors： Bouffet E,Pierre-Kahn A,Marchal JC,Jouvet A,Kalifa C,Choux M,Dhellemmes P,Guérin J,Tremoulet M,Mottolese C

更新日期：1998-12-01 00:00:00

abstract：:Individualization of treatment using judicious combinations of external and intracavitary irradiation remains the cornerstone of the radiation management of carcinoma of the cervix. The inherent propensity of this cancer to either confine itself to the pelvis or else spread in a systematic and predictable manner throu...

journal_title：Cancer

authors： Rotman M,John M,Boyce J

更新日期：1981-07-15 00:00:00

abstract：BACKGROUND:Chronic myeloid leukemia (CML) may progress to blast phase (BP) at the rate of 1% to 1.5% per year. With the use of single-agent tyrosine kinase inhibitors, median overall survival ranges between 7 and 11 months. METHODS:The outcome was analyzed for 42 patients with lymphoid BP-CML who were treated with hyp...

journal_title：Cancer

authors： Strati P,Kantarjian H,Thomas D,O'Brien S,Konoplev S,Jorgensen JL,Luthra R,Abruzzo L,Jabbour E,Quintas-Cardama A,Borthakur G,Faderl S,Ravandi F,Cortes J

更新日期：2014-02-01 00:00:00

abstract：BACKGROUND:Recently, adenomatous hyperplasia (AH) of the liver, a sizable parenchymal nodule in the cirrhotic liver, has been considered a preneoplastic lesion in human hepatocarcinogenesis. METHODS:The authors evaluated cell proliferative activity by immunostaining for proliferating cell nuclear antigen (PCNA) in AH ...

journal_title：Cancer

authors： Terada T,Nakanuma Y

更新日期：1992-08-01 00:00:00

abstract：BACKGROUND:Long-term survivors of testicular cancer (TC) who received cisplatin-based chemotherapy have an increased risk of cardiovascular disease. A cross-sectional study was performed to objectively assess cardiovascular risk, subclinical atherosclerosis, and endothelial function in long-term survivors of TC. METHO...

journal_title：Cancer

authors： Vaughn DJ,Palmer SC,Carver JR,Jacobs LA,Mohler ER

更新日期：2008-05-01 00:00:00

abstract：:Seventy-three women with metastatic breast cancer were treated with aminoglutethimide and dexamethasone. No complete responses occurred. Ten patients (16%) achieved partial responses (mean duration, 12 months). The proportions of patients responding by disease site were breast (50%), nodes (33%), skin (23%), bone (16%...

journal_title：Cancer

authors： Asbury RF,Bakemeier RF,Fölsch E,McCune CS,Savlov E,Bennett JM

更新日期：1981-04-15 00:00:00

abstract：:The cytologic, histologic and ultrastructural features of a malignant carcinomatous mesothelioma of the tunica vaginalis testis in a 30-year old patient are described. This is the first such case with preoperative diagnosis by cytologic examination of hydrocele fluid and the second with documented history of exposure ...

journal_title：Cancer

authors： Japko L,Horta AA,Schreiber K,Mitsudo S,Karwa GL,Singh G,Koss LG

更新日期：1982-01-01 00:00:00

abstract：BACKGROUND:A study was undertaken to evaluate results of surgery and radiotherapy (RT) for high-risk extracranial chondrosarcomas. METHODS:Between 1986 and 2006, 60 patients underwent surgery and RT for extracranial high-risk chondrosarcoma. Preoperative RT (median, 50 gray [Gy]) and postoperative RT (median, 60 Gy) w...

journal_title：Cancer

authors： Goda JS,Ferguson PC,O'Sullivan B,Catton CN,Griffin AM,Wunder JS,Bell RS,Kandel RA,Chung PW

更新日期：2011-06-01 00:00:00

abstract：BACKGROUND:Sacituzumab govitecan (IMMU-132), an antitrophoblastic cell-surface antigen (anti-Trop-2) humanized antibody-SN-38 conjugate, had encouraging efficacy in the phase 1 clinical trial. This report further examines the pharmacokinetics and safety of multiple cycles of IMMU-132 at doses of 8 or 10 mg/kg in patien...

journal_title：Cancer

authors： Ocean AJ,Starodub AN,Bardia A,Vahdat LT,Isakoff SJ,Guarino M,Messersmith WA,Picozzi VJ,Mayer IA,Wegener WA,Maliakal P,Govindan SV,Sharkey RM,Goldenberg DM

更新日期：2017-10-01 00:00:00

abstract：:Forty-nine patients with transitional urothelial tract tumors received methotrexate: 0.5-1.0 mg/kg I.V. Q W (40 patients) or 250 mg/M2 in a 2-hour infusion with citrovorum factor rescue 24 hours later (nine patients). Eleven (26%, 95% confidence limits 13-39%) of 42 patients with bidimensionally measurable metastases ...

journal_title：Cancer

authors： Natale RB,Yagoda A,Watson RC,Whitmore WF,Blumenreich M,Braun DW Jr

更新日期：1981-03-15 00:00:00

abstract：:The authors report on five patients with secondary leukemia (SL) and one of the "specific" chromosomal rearrangements usually encountered in de novo acute nonlymphoblastic leukemia: inv(16), t(15;17), t(8;21), and t(9;11). They were characterized by solid tumor as the primary malignancy in four of five cases, absence ...

journal_title：Cancer

authors： Fenaux P,Lucidarme D,Laï JL,Bauters F

更新日期：1989-06-15 00:00:00

abstract：BACKGROUND:Uterine serous carcinoma (USC) is not recognized as part of any defined hereditary cancer syndrome, and its association with hereditary breast and ovarian carcinoma and Lynch syndrome are uncertain. METHODS:Using targeted capture and massively parallel genomic sequencing, 151 subjects with USC were assessed...

journal_title：Cancer

authors： Pennington KP,Walsh T,Lee M,Pennil C,Novetsky AP,Agnew KJ,Thornton A,Garcia R,Mutch D,King MC,Goodfellow P,Swisher EM

更新日期：2013-01-15 00:00:00

abstract：:BALB/c mice were hyperimmunized with ACHN (ATCC CRL 1611, American Type Culture Collection, Rockville, Maryland), a stable in vitro cell line derived from a malignant pleural effusion in a 22-year-old man with renal cell carcinoma. The hyperimmune spleen cells were fused with NS-1 murine myeloma cells using polyethyle...

journal_title：Cancer

authors： Kochevar J

更新日期：1987-06-15 00:00:00