Evaluation of response criteria in advanced lung cancer.

abstract：BACKGROUND:The specific activity of the non-receptor protein tyrosine kinase, Src, is increased in the majority of colon and rectal adenocarcinomas compared to normal mucosa. However, the prognostic significance of this difference is unknown. The objective of the current study was to determine if Src activity is a mark...

journal_title：Cancer

authors： Aligayer H,Boyd DD,Heiss MM,Abdalla EK,Curley SA,Gallick GE

更新日期：2002-01-15 00:00:00

abstract：BACKGROUND:Epithelioid sarcoma is a highly malignant soft tissue tumor that is largely resistant to conventional chemotherapy and radiotherapy. Because paclitaxel has been proven to be effective in other human malignancies refractory to conventional chemotherapy, the authors analyzed the in vitro growth inhibitory effe...

journal_title：Cancer

authors： Reinecke P,Knopf C,Schmitz M,Schneider EM,Gabbert HE,Gerharz CD

更新日期：2000-04-01 00:00:00

abstract：:The authors administered high-dose chemotherapy with cyclophosphamide, BCNU (carmustine) and VP-16 (etoposide) plus autologous bone marrow transplantation (ABMT) to 22 adult patients with relapsed acute leukemia in second or subsequent remission. The marrow was not treated ex vivo. The long-term, disease-free survival...

journal_title：Cancer

authors： Spinolo JA,Dicke KA,Horwitz LJ,Jagannath S,McCredie K,Estey E,Kantarjian H,Zander AR,Keating M,Spitzer G

更新日期：1990-08-15 00:00:00

abstract：BACKGROUND:The Tecumseh Community Health Study (TCHS), initiated in 1959 at the University of Michigan School of Public Health, has provided a resource for long term prospective studies of the incidence of cancer in the setting of a midwestern rural farming community. METHODS:A survey of total and site specific cancer...

journal_title：Cancer

authors： Waterhouse D,Carman WJ,Schottenfeld D,Gridley G,McLean S

更新日期：1996-02-15 00:00:00

abstract：BACKGROUND:Insulin-like growth factor I (IGF-I) is a potent mitogen for breast cancer cells. The majority of IGF-I in plasma is bound to IGF binding proteins (IGFBPs), which modulate the biologic effects of IGF-I. METHODS:Plasma concentrations of IGF-I, IGFBP-I, and IGFBP-3 were compared between 40 postmenopausal brea...

journal_title：Cancer

authors： Lahti EI,Knip M,Laatikainen TJ

更新日期：1994-07-15 00:00:00

abstract：BACKGROUND:Benign and malignant pancreatic mucinous tumors differ in proliferative activity, production of tumor markers, and expression of growth factors. DNA ploidy is a useful index of aggressiveness and poor survival in ductal adenocarcinoma, but has not been studied in pancreatic cystic tumors. METHODS:The DNA pl...

journal_title：Cancer

authors： Southern JF,Warshaw AL,Lewandrowski KB

更新日期：1996-01-01 00:00:00

abstract：:Why are older black women screened less for breast cancer? What can be done to narrow the racial gap in mammography screening? These are the questions addressed by the Save Our Sisters (SOS) Project, a pilot demonstration study funded by the National Cancer Institute in a rural county of North Carolina. The target pop...

journal_title：Cancer

authors： Eng E

更新日期：1993-08-01 00:00:00

abstract：BACKGROUND:To retrospectively evaluate the significance of morphologic examination and ancillary studies performed on bilateral bone marrow biopsy specimens, 1864 bone marrow samples were studied. METHODS:Bilateral bone marrow biopsy specimens included 883 specimens that were evaluated for involvement by non-Hodgkin l...

journal_title：Cancer

authors： Wang J,Weiss LM,Chang KL,Slovak ML,Gaal K,Forman SJ,Arber DA

更新日期：2002-03-01 00:00:00

abstract：:Findings from 1665 women with primary breast cancer, treated at 34 NSABP institutions in Canada and the United States, have failed to demonstrate that patients with medial-central tumors had a greater probability of developing distant metastases or dying than did those with lateral tumors despite the greater incidence...

journal_title：Cancer

authors： Fisher B,Wolmark N,Redmond C,Deutsch M,Fisher ER

更新日期：1981-10-15 00:00:00

abstract：:Pel-Epstein fever cycles, consisting of 1-2 weeks of high fever separated by afebrile periods of the same duration, are classically characteristic of Hodgkin's disease. Clinical observation has determined that the lymph nodes enlarge during periods of fever and reduce in size as the fever subsides. To our knowledge, t...

journal_title：Cancer

authors： Scanlon GT,Castellino RA,Rudders R

更新日期：1975-12-01 00:00:00

abstract：:Transforming growth factors (TGF) are polypeptides that stimulate anchorage-independent growth of various nontransformed cells in vitro. Transforming growth factors have been found in tumor extracts and in the urine of cancer patients. The specific questions of our study were whether TGF activity can be detected in ma...

journal_title：Cancer

authors： Hanauske AR,Arteaga CL,Clark GM,Buchok J,Marshall M,Hazarika P,Pardue RL,Von Hoff DD

更新日期：1988-05-01 00:00:00

abstract：BACKGROUND:The Danish Breast Cancer Cooperative Group (DBCG) 77B trial examined the relative efficacy of levamisole, single-agent oral cyclophosphamide, and the classic combination of cyclophosphamide, methotrexate, and 5-fluorouracil (CMF) against no adjuvant systemic therapy in high-risk breast cancer patients. The a...

journal_title：Cancer

authors： Ejlertsen B,Mouridsen HT,Jensen MB,Andersen J,Andersson M,Kamby C,Knoop AS,Danish Breast Cancer Cooperative Group.

更新日期：2010-05-01 00:00:00

abstract：:Review of the consultation records of the Gastrointestinal Surgical Oncology service at Roswell Park Memorial Institute from 1982 to 1987 revealed 22 patients with a clinical diagnosis of neutropenic enterocolitis. Ninety-one percent of the patients had hematologic malignancies, and 95% were receiving cytotoxic chemot...

journal_title：Cancer

authors： Wade DS,Nava HR,Douglass HO Jr

更新日期：1992-01-01 00:00:00

abstract：BACKGROUND:In regional lymph node metastasis of cutaneous melanoma, the number and volume of involved lymph nodes are the most important prognostic factors. Several studies have revealed that palpation of the lymphatic drainage area(s) and regional lymph nodes has a high rate of false-negative results during follow-up....

journal_title：Cancer

authors： Blum A,Schlagenhauff B,Stroebel W,Breuninger H,Rassner G,Garbe C

更新日期：2000-06-01 00:00:00

abstract：:The potential role of paraneoplastic Cushing's syndrome (CS) was assessed on the clinical course of patients with small cell lung cancer. A retrospective comparison was done of complications and survival rates according to the presence or absence of CS in patients with small cell lung cancer who died within 90 days of...

journal_title：Cancer

authors： Dimopoulos MA,Fernandez JF,Samaan NA,Holoye PY,Vassilopoulou-Sellin R

更新日期：1992-01-01 00:00:00

abstract：BACKGROUND:Various chemotherapy agents, especially of the alkylating category, have been associated with premature ovarian failure but there is no quantitative evidence of chemotherapy-induced ovarian damage in humans. The aim was to quantify the impact of chemotherapy on primordial follicle reserve and stromal functio...

journal_title：Cancer

authors： Oktem O,Oktay K

更新日期：2007-11-15 00:00:00

abstract：:The results of surgical treatment alone for 142 cases of carcinoma of the rectum and rectosigmoid from the Massachusetts General Hospital were reviewed. The incidence of local failure as any component of failure was found to be strongly dependent on the pathologic stage, and for Dukes' A was 8.0% (3/39); Dukes' B, 31%...

journal_title：Cancer

authors： Rich T,Gunderson LL,Lew R,Galdibini JJ,Cohen AM,Donaldson G

更新日期：1983-10-01 00:00:00

abstract：BACKGROUND:The incidence, risk factors, time course, and impact on survival of venous thromboembolism (VTE) in a large, population-based study of patients with bladder cancer have not been identified previously. METHODS:The California Cancer Registry was merged with the California Patient Discharge Data Set to determi...

journal_title：Cancer

authors： Sandhu R,Pan CX,Wun T,Harvey D,Zhou H,White RH,Chew HK

更新日期：2010-06-01 00:00:00

abstract：BACKGROUND:Chronic disseminated candidiasis (CDC) is a serious complication of treatment in patients with acute leukemia. Although some general risk factors are known to predispose to systemic fungal infections, few studies have addressed the relevance of certain clinical and laboratory features in patients with CDC. ...

journal_title：Cancer

authors： Sallah S,Wan JY,Nguyen NP,Vos P,Sigounas G

更新日期：2001-09-15 00:00:00

abstract：BACKGROUND:The Female Sexual Function Index (FSFI) is the most commonly used self-report instrument to measure sexual functioning among women cancer survivors. Despite this, the validity and reliability of the FSFI for use in cancer populations has not been established. METHODS:Data were combined from 3 separate insti...

journal_title：Cancer

authors： Baser RE,Li Y,Carter J

更新日期：2012-09-15 00:00:00

abstract：BACKGROUND:Although thin cutaneous melanomas generally have a favorable prognosis, in some cases they may undergo progression. The current study was undertaken to identify variables that may predict a more aggressive clinical outcome in these patients. In addition to classic clinicopathologic features, the authors test...

journal_title：Cancer

authors： Massi D,Franchi A,Borgognoni L,Reali UM,Santucci M

更新日期：1999-03-01 00:00:00

abstract：:Lymphocytic and plasmocytic infiltration surrounding a malignant tumor probably represents an immunologic response of the host directed against the neoplasm. It has been documented that lymphocytic infiltration has a favorable effect on prognosis in a number of human tumor systems, including cutaneous melanoma. In the...

journal_title：Cancer

authors： Lang JR,Davidorf FH,Baba N

更新日期：1977-11-01 00:00:00

abstract：BACKGROUND:Obesity has been shown to affect breast carcinoma prognosis, with the heaviest women having a higher mortality due to breast carcinoma. Few studies have focused on premenopausal women or the correlation of body mass index (BMI) to tumor characteristics related to prognosis. METHODS:The authors conducted a p...

journal_title：Cancer

authors： Daling JR,Malone KE,Doody DR,Johnson LG,Gralow JR,Porter PL

更新日期：2001-08-15 00:00:00

abstract：:The acquisition by tumor cells of the ability to metastasize is the critical event in the clinical course of most human neoplastic disease. While metastasis plays a pivotal role in the ultimate success of failure of therapy, it is in fact a result of a more insidious malignant process termed tumor progression. It is t...

journal_title：Cancer

authors： Frost P,Fidler IJ

更新日期：1986-07-15 00:00:00

abstract：BACKGROUND:Disseminated intravascular coagulation (DIC) and primary fibrinolysis have both been reported in association with prostate carcinoma. The correct diagnosis of the coagulopathy can be difficult and the appropriate management controversial. METHODS:A case is presented of a man in whom DIC and soft tissue hemo...

journal_title：Cancer

authors： Cooper DL,Sandler AB,Wilson LD,Duffy TP

更新日期：1992-08-01 00:00:00

abstract：:Immunoproliferative small intestinal diseases (IPSID), previously known as Mediterranean Lymphomas, constitute more than 60% of the non-Burkitt's small intestinal lymphomas in Tunisia. A multidisciplinary study of IPSID was undertaken by the Tunisian/French Lymphoma Study Group in 1980 to reach a better understanding ...

journal_title：Cancer

authors： Tabbane F,Mourali N,Cammoun M,Najjar T

更新日期：1988-04-15 00:00:00

abstract：:Fifty-eight patients with 62 pathologic fractures secondary to metastatic disease were admitted to a rehabilitation hospital during a 5-year period. Thirty-four patients were discharged home, 7 were transferred to other facilities, and 17 died. The average hospital stay for the patients who went home (37 days) was onl...

journal_title：Cancer

authors： Bunting RW,Boublik M,Blevins FT,Dame CC,Ford LA,Lavine LS

更新日期：1992-01-01 00:00:00

abstract：:The clinical course of 29 patients with idiopathic refractory sideroblastic anemia studied by us was reviewed. Four patients developed acute leukemia. We were able to find 27 out of 268 cases of idiopathic refractory sideroblastic anemia reported in the literature which terminated in acute leukemia. Nine of these were...

journal_title：Cancer

authors： Cheng DS,Kushner JP,Wintrobe MM

更新日期：1979-08-01 00:00:00

abstract：:Malignant fibrous histiocytoma of soft tissues (MFH), a mesenchymal tumor of varied morphologic patterns and cell types, sometimes contains bone and cartilage. Such bony and cartilaginous elements in a pleomorphic MFH may pose a difficult diagnostic challenge. An MFH with bone and cartilage can be distinguished from e...

journal_title：Cancer

authors： Bhagavan BS,Dorfman HD

更新日期：1982-02-01 00:00:00

abstract：BACKGROUND:Clinical trials of monoclonal antibodies in combination with chemotherapy have reported previously unattained response rates in patients with B-cell chronic lymphocytic leukemia (B-CLL); however, the analysis of ZAP-70 protein and/or CD38 may explain better the discordant outcomes independent of treatment. ...

journal_title：Cancer

authors： Del Poeta G,Del Principe MI,Consalvo MA,Maurillo L,Buccisano F,Venditti A,Mazzone C,Bruno A,Gianní L,Capelli G,Lo Coco F,Cantonetti M,Gattei V,Amadori S

更新日期：2005-12-15 00:00:00