Cell proliferative activity in adenomatous hyperplasia of the liver and small hepatocellular carcinoma. An immunohistochemical study demonstrating proliferating cell nuclear antigen.

abstract：BACKGROUND:p16 is strongly overexpressed in dysplastic cervical cells because of the transforming activity of the E7 oncogene of all high-risk human papillomavirus (HR-HPV) types and may be easily revealed by immunochemistry: p16 may, therefore, be considered a surrogate marker for the activated oncogene expression of ...

journal_title：Cancer

authors： Carozzi F,Cecchini S,Confortini M,Becattini V,Cariaggi MP,Pontenani G,Sani C,Ciatto S

更新日期：2006-04-25 00:00:00

abstract：:Forty patients with disseminated malignant melanoma were treated with triple combination chemotherapy consisting of Imidazole Carboxamide, BCNU and Vincristine. Seventeen of 40 patients (42.5%) showed significant responses including three complete responses. Responses were seen in cutaneous, lymph node and pulmonary m...

journal_title：Cancer

authors： Cohen SM,Greenspan EM,Ratner LH,Weiner MJ

更新日期：1977-01-01 00:00:00

abstract：BACKGROUND:The purported lack of long term modern prostate brachytherapy outcome data continues to lead many physicians to recommend other, more traditional treatments. This concern for long term results has encouraged the authors to supplement their earlier 10-year follow-up of patients receiving brachytherapy; in the...

journal_title：Cancer

authors： Ragde H,Korb LJ,Elgamal AA,Grado GL,Nadir BS

更新日期：2000-07-01 00:00:00

abstract：BACKGROUND:Cisplatin (CDDP) administration concomitant with radiotherapy (RT) for the treatment of locally advanced cervical cancer has evolved from an inpatient 5-day every 21-day regimen to a weekly outpatient regimen. This study was designed to test for differences in progression-free survival (PFS) and toxicity bet...

journal_title：Cancer

authors： Einstein MH,Novetsky AP,Garg M,Hailpern SM,Huang GS,Glueck A,Fields AL,Kalnicki S,Goldberg GL

更新日期：2007-01-01 00:00:00

abstract：:A 1-year-old infant with von Recklinghausen's neurofibromatosis was seen because of increasing clitoral enlargement over a 7-month period. The mother, who also had neurofibromatosis, was treated 2 years beforehand for an acoustic neuroma. The child was treated by radical clitorectomy. Pathologic examination revealed m...

journal_title：Cancer

authors： Thomas WJ,Bevan HE,Hooper DG,Downey EJ

更新日期：1989-06-01 00:00:00

abstract：:Peritoneal mesothelioma in a 61-year-old man, occurred 26 years after abdominal radiotherapy for a testicular seminoma. The patient had no history of asbestos exposure. After asbestos, radiation is the second most frequent defined cause of mesothelioma in North America, but the number of well-documented cases is small...

journal_title：Cancer

authors： Gilks B,Hegedus C,Freeman H,Fratkin L,Churg A

更新日期：1988-05-15 00:00:00

abstract：:Responding to growing concerns regarding the safety, quality, and efficacy of cancer care in the United States, the Institute of Medicine (IOM) of the National Academy of Sciences commissioned a comprehensive review of cancer care delivery in the US health care system in the late 1990s. The National Cancer Policy Boar...

journal_title：Cancer

authors： Spinks T,Albright HW,Feeley TW,Walters R,Burke TW,Aloia T,Bruera E,Buzdar A,Foxhall L,Hui D,Summers B,Rodriguez A,Dubois R,Shine KI

更新日期：2012-05-15 00:00:00

abstract：:An unusual upper esophageal polypoid tumor was found to be predominantly a carcinoid tumor and in part a mucin-producing adenocarcinoma. A review of literature showed this to be a unique tumor in this location. ...

journal_title：Cancer

authors： Chong FK,Graham JH,Madoff IM

更新日期：1979-11-01 00:00:00

abstract：BACKGROUND:Hispanics now represent a majority of residents in Miami-Dade County, Florida. In this report, the authors present new cancer incidence and mortality data for South Florida's Hispanic men for the period 1990-1998 and compare them with data from a previous report from the 1980s. Periodic updating of cancer in...

journal_title：Cancer

authors： Wilkinson JD,Wohler-Torres B,Trapido E,Fleming LE,MacKinnon J,Voti L,Peace S

更新日期：2002-02-15 00:00:00

abstract：BACKGROUND:A Phase II study with carboplatin, methotrexate, and vinblastine (CAMV) was conducted with patients who had advanced urothelial cancer to investigate the activity and toxicity of carboplatin when used in combination chemotherapy. METHODS:Thirty-six patients with advanced urothelial cancer were treated with ...

journal_title：Cancer

authors： Boccardo F,Pace M,Guarneri D,Canobbio L,Curotto A,Martorana G

更新日期：1994-04-01 00:00:00

abstract：BACKGROUND:A 59-year-old male developed intractable hiccups during monthly therapy with high dose dexamethasone for multiple myeloma. Hiccups would begin hours after his first dose and continue over the 4 days of therapy. He sought assistance after his attempt at home remedies failed and the hiccups became exhausting. ...

journal_title：Cancer

authors： Cersosimo RJ,Brophy MT

更新日期：1998-01-15 00:00:00

abstract：:Thyroglobulin messenger RNA (mRNA) was located and quantified in tissue sections of differentiated human thyroid cancers by in situ hybridization using cloned complementary DNA probes. The cells of the well-differentiated follicular and papillary forms contained similar levels of thyroglobulin mRNA, corresponding to a...

journal_title：Cancer

authors： Bergé-Lefranc JL,Cartouzou G,De Micco C,Fragu P,Lissitzky S

更新日期：1985-07-15 00:00:00

abstract：BACKGROUND:Validation of the prognostic indices for the recurrence-free interval of patients with parotid carcinoma, the development of which was described in a previous report, is needed to be confident of their generalizability and justified prospective use. METHODS:The Dutch Cooperative Group on Head and Neck Cance...

journal_title：Cancer

authors： Vander Poorten VL,Hart AA,van der Laan BF,Baatenburg de Jong RJ,Manni JJ,Marres HA,Meeuwis CA,Lubsen H,Terhaard CH,Balm AJ

更新日期：2003-03-15 00:00:00

abstract：BACKGROUND:Because the prostatic capsule is often indistinct, recognition of extraprostatic extension by carcinoma depends heavily on the identification of carcinoma cells in the periprostatic adipose tissue. However, the distribution of adipose tissue along the prostatic surfaces has not been studied extensively. MET...

journal_title：Cancer

authors： Hong H,Koch MO,Foster RS,Bihrle R,Gardner TA,Fyffe J,Ulbright TM,Eble JN,Cheng L

更新日期：2003-04-01 00:00:00

abstract：BACKGROUND:Quantified, human hemoglobin (Hb)-specific, immunochemical fecal occult blood test (IFOBT) measurements are now used for colorectal cancer (CRC) screening. The objective was to evaluate sensitivity and specificity for CRC and advanced adenomatous polyps (APs) by the fecal Hb threshold used to determine a pos...

journal_title：Cancer

authors： Rozen P,Comaneshter D,Levi Z,Hazazi R,Vilkin A,Maoz E,Birkenfeld S,Niv Y

更新日期：2010-05-01 00:00:00

abstract：:Compliance in oncology clinic attendance was prospectively evaluated over a 12-month period at Harlem Hospital Center, an inner city municipal facility serving a predominantly black population. One hundred patients were followed (97 blacks, 2 Hispanics, 1 white) with an average age of 60 years. There were 41 men and 5...

journal_title：Cancer

authors： Garrett TJ,Ashford A,Savage DG

更新日期：1986-08-01 00:00:00

abstract：BACKGROUND:The delivery of effective treatment for pediatric solid tumors poses a particular challenge to centers in middle-income countries (MICs) that already are vigorously addressing pediatric cancer. The objective of this study was to improve the current understanding of barriers to effective treatment of pediatri...

journal_title：Cancer

authors： Friedrich P,Ortiz R,Fuentes S,Gamboa Y,Ah Chu-Sanchez MS,Arambú IC,Montero M,Báez F,Rodríguez-Galindo C,Antillón-Klussmann F,Central American Association of Pediatric Hematologists and Oncologists (AHOPCA).

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Carboplatin-based regimens have demonstrated activity in pediatric patients with low-grade glioma (LGG). However, carboplatin hypersensitivity reaction (Cb HSR) represents a common and limiting factor for the continuation of therapy. METHODS:The objectives of this study were to describe the prevalence, char...

journal_title：Cancer

authors： Lafay-Cousin L,Sung L,Carret AS,Hukin J,Wilson B,Johnston DL,Zelcer S,Silva M,Odame I,Mpofu C,Strother D,Bouffet E

更新日期：2008-02-15 00:00:00

abstract：BACKGROUND:Constitutional or somatic mosaic epimutations are increasingly recognized as a mechanism of gene dysregulation resulting in cancer susceptibility. Beckwith-Wiedemann syndrome is the cancer predisposition syndrome most commonly associated with epimutation and is extremely variable in its phenotypic presentati...

journal_title：Cancer

authors： Fiala EM,Ortiz MV,Kennedy JA,Glodzik D,Fleischut MH,Duffy KA,Hathaway ER,Heaton T,Gerstle JT,Steinherz P,Shukla N,McNeer N,Tkachuk K,Bouvier N,Cadoo K,Carlo MI,Latham A,Dubard Gault M,Joseph V,Kemel Y,Kentsis A,

更新日期：2020-07-01 00:00:00

abstract：BACKGROUND:Lung carcinoma remains the major cause of cancer death in North America and is even more common among military veterans. The objective of this study was to determine whether there were differences in the characteristics and survival of Pennsylvania patients with lung carcinoma in the Veterans Administration ...

journal_title：Cancer

authors： Campling BG,Hwang WT,Zhang J,Thompson S,Litzky LA,Vachani A,Rosen IM,Algazy KM

更新日期：2005-08-15 00:00:00

abstract：:The histopathology of 43 cases of carcinoma in the extrahepatic bile ducts was reported. All four cases of noninfiltrating carcinoma were papillary or polypoid in gross shape. Only one of the eight cases of papillary or polypoid cancers penetrated beyond the fibromuscular layer of the bile ducts, while most cases of n...

journal_title：Cancer

authors： Kozuka S,Tsubone M,Hachisuka K

更新日期：1984-07-01 00:00:00

abstract：BACKGROUND:For patients with stage III through IVB head and neck squamous cell carcinoma (HNSCC), concurrent high-dose cisplatin plus radiation therapy is a widely accepted standard of care. HNSCC tumors that express high levels of vascular endothelial growth factor have been associated with a worse prognosis, and beva...

journal_title：Cancer

authors： Fury MG,Lee NY,Sherman E,Lisa D,Kelly K,Lipson B,Carlson D,Stambuk H,Haque S,Shen R,Kraus D,Shah J,Pfister DG

更新日期：2012-10-15 00:00:00

abstract：BACKGROUND:Patients with familial adenomatous polyposis develop periampullary adenomas at a high rate. However, little is known regarding the factors that control the growth, the natural history, or the malignant potential of these tumors. METHODS:In this study, the authors systematically evaluated the expression of t...

journal_title：Cancer

authors： Resnick MB,Gallinger S,Wang HH,Odze RD

更新日期：1995-07-15 00:00:00

abstract：BACKGROUND:In view of the many studies of early stage colorectal carcinoma from Japan, it is essential to know whether the criteria for the histologic diagnosis of colorectal carcinoma are similar in Japan and Western countries. METHODS:Eight expert pathologists from Japan (4), North America (2), and Europe (2) indivi...

journal_title：Cancer

authors： Schlemper RJ,Itabashi M,Kato Y,Lewin KJ,Riddell RH,Shimoda T,Sipponen P,Stolte M,Watanabe H

更新日期：1998-01-01 00:00:00

abstract：:One hundred eighty-four patients with advanced measurable colorectal cancer not previously treated with chemotherapy were entered into a prospective randomized clinical trial by the Mid-Atlantic Oncology Program (MAOP) to assess the value of weekly cisplatin (20 mg/m2) when added to a protracted schedule of 5-fluorour...

journal_title：Cancer

authors： Lokich JJ,Ahlgren JD,Cantrell J,Heim WJ,Wampler GL,Gullo JJ,Fryer JG,Alt DE

更新日期：1991-01-01 00:00:00

abstract：:Seventeen cases of intranasal epithelial tumors are reviewed. Thirteen were epithelial papillomas and four were squamous cell carcinomas associated with epithelial papillomas. In two cases followed over a 10 year period, transformation from an initial papilloma into a carcinoma was demonstrated. The histopathologic ca...

journal_title：Cancer

authors： Lasser A,Rothfeld PR,Shapiro RS

更新日期：1976-12-01 00:00:00

abstract：:Elective irradiation of sites of potential occult tumor spread is often part of a patient's radiation therapy program. The required radiation dose (D) depends on the probability that occult disease exists (P(occ)), the number of sites at risk (A), the number of tumor clonogens present (Ni), their radiation sensitivity...

journal_title：Cancer

authors： Marks LB

更新日期：1990-12-15 00:00:00

abstract：:Retinoblastoma should not be considered as the exceptional childhood cancer that shows dominant inheritance, but rather as the typical childhood cancer that embraces a prezygotic and postzygotic subgroup. Postzygotic cases are conceived as involving mutation as a first step too, but with the mutation in somatic rather...

journal_title：Cancer

authors： Knudson AG Jr

更新日期：1975-03-01 00:00:00

abstract：BACKGROUND:The purpose of this project was to develop the M. D. Anderson Symptom Inventory (MDASI), a brief measure of the severity and impact of cancer-related symptoms. METHODS:A list of symptoms was generated from symptom inventories and by panels of clinicians. Twenty-six symptoms and 6 interference items were rat...

journal_title：Cancer

authors： Cleeland CS,Mendoza TR,Wang XS,Chou C,Harle MT,Morrissey M,Engstrom MC

更新日期：2000-10-01 00:00:00

abstract：BACKGROUND:The incidence of bronchioloalveolar carcinoma of the lung (BAC), a pathologically distinct type of nonsmall cell lung carcinoma (NSCLC), appears to be rising. In this study, the authors compared data on the clinical presentation and clinical courses of patients with Stage IIIB and IV BAC with data on other t...

journal_title：Cancer

authors： Breathnach OS,Ishibe N,Williams J,Linnoila RI,Caporaso N,Johnson BE

更新日期：1999-10-01 00:00:00