Mucin-producing carcinoid ("composite tumor") of upper third of esophagus: a variant of carcinoid tumor.

abstract：:Between the years 1973-1977, 152 male patients from 28 participating Veterans Hospitals with histologically proven nonresectable cancer of the pancreas were randomized in a two-arm study. The treated group was to receive combination chemotherapy with 5-FU and CCNU, and the controls were to receive no chemotherapy. Bot...

journal_title：Cancer

authors： Frey C,Twomey P,Keehn R,Elliott D,Higgins G

更新日期：1981-01-01 00:00:00

abstract：BACKGROUND:The polyamine system is a promising target for anticancer therapy. Ideally, an antineoplastic compound affecting this system should inhibit both ornithine decarboxylase and the polyamine transporter, and toxicity should be mild. Agmatine, decarboxylated L-arginine, appears to be such a compound. METHODS:Ade...

journal_title：Cancer

authors： Molderings GJ,Kribben B,Heinen A,Schröder D,Brüss M,Göthert M

更新日期：2004-08-15 00:00:00

abstract：:A staging system was proposed for chronic myeloid leukemia (CML) that groups patients into three stages (I, II, and III), each with two subclasses (A and B). The system uses pathologic parameters, of which the percentage of blasts in the blood and bone marrow is the most important. CML is defined as a myeloproliferati...

journal_title：Cancer

authors： Ross DW,Brunning RD,Kantarjian HM,Koeffler HP,Ozer H

更新日期：1993-06-01 00:00:00

abstract：:A 22-micron glass microsphere called TheraSphere (Theragenics Corp., Atlanta, GA) has been developed in which yttrium 89 oxide is incorporated into the glass matrix and is activated by neutron bombardment to form the beta-emitting isotope yttrium 90 (Y 90) before using the spheres as radiotherapeutic vehicles. The inj...

journal_title：Cancer

authors： Wollner I,Knutsen C,Smith P,Prieskorn D,Chrisp C,Andrews J,Juni J,Warber S,Klevering J,Crudup J

更新日期：1988-04-01 00:00:00

abstract：BACKGROUND:Late menarche, early menopause, high parity, and early first birth decrease the risk of development of breast cancer. The influence of these factors on the survival of breast cancer patients has not been explained. METHODS:A group of 1885 patients with operable breast cancer was studied retrospectively. A u...

journal_title：Cancer

authors： Korzeniowski S,Dyba T

更新日期：1994-09-01 00:00:00

abstract：BACKGROUND:A previous study found that medroxyprogesterone acetate (MPA) delayed the in vivo growth of three (AsPC-1, Capan-2, and MiaPaCa-2) of nine human pancreatic carcinoma cell lines transplanted into nude mice (Cancer 1995; 75:1263-72). The current study was undertaken to evaluate the basis for this inhibitor. M...

journal_title：Cancer

authors： Abe M,Yamashita J,Ogawa M

更新日期：2000-05-01 00:00:00

abstract：BACKGROUND:Endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) biopsy allows the detailed imaging and FNA not only of both intramural and extramural structures and lesions of the gastrointestinal (GI) tract but also of various intraabdominal organs. Thus, EUS-FNA biopsy offers a novel opportunity to evaluate ...

journal_title：Cancer

authors： Jhala NC,Jhala D,Eloubeidi MA,Chhieng DC,Crowe DR,Roberson J,Eltoum I

更新日期：2004-10-25 00:00:00

abstract：BACKGROUND:Immunohistological markers specific for a single type of epithelium are rare. Recently, urothelium tissue-specific genes were cloned. The genes encoded a family of transmembrane proteins, uroplakins, that are expressed only in urothelial mucosa. Using uroplakin antibodies on paraffin-embedded tissue, a previ...

journal_title：Cancer

authors： Xu X,Sun TT,Gupta PK,Zhang P,Nasuti JF

更新日期：2001-06-25 00:00:00

abstract：:Because we found it illogical to attempt measurement of nonmeasurable but visible tumors in patients with advanced lung cancer, we devised and used a separate set of response criteria for patients with evaluable, nonmeasurable tumors. Patients with evaluable disease who had obtained a tumor regression after therapy we...

journal_title：Cancer

authors： Eagan RT,Fleming TR,Schoonover V

更新日期：1979-09-01 00:00:00

abstract：:If health professionals wish to help increase the number of older adults who get screened regularly to detect cancer at an early stage, they must first understand the barriers to screening that older people experience. This paper discusses the barriers older women face regarding mammography screening. Data from Americ...

journal_title：Cancer

authors： Rubenstein L

更新日期：1994-10-01 00:00:00

abstract：BACKGROUND:The objectives of this study were to evaluate survival among current smokers, former smokers, and never smokers who are diagnosed with non-small cell lung cancer (NSCLC). METHODS:The study included patients who participated in the National Comprehensive Cancer Network's NSCLC Database Project. Current, form...

journal_title：Cancer

authors： Ferketich AK,Niland JC,Mamet R,Zornosa C,D'Amico TA,Ettinger DS,Kalemkerian GP,Pisters KM,Reid ME,Otterson GA

更新日期：2013-02-15 00:00:00

abstract：:This study is based on 38 patients, each of whom had a malignant lymphoma in which the gonad was the site of the main tumor mass at the time of diagnosis. Histiocytic lymphoma was the predominant type in the 27 male patients; in the 11 female patients, poorly differentiated lymphocytic lymphoma was the most frequent t...

journal_title：Cancer

authors： Paladugu RR,Bearman RM,Rappaport H

更新日期：1980-02-01 00:00:00

abstract：:Thrombocytosis above 40.0 X 10(4)/mm3 occurred in five of six (83%) patients with malignant mesothelioma. In contrast, the incidence of thrombocytosis was 7.5% in patients with lung adenocarcinoma, 12.5% in squamous cell carcinoma, 5.1% in small cell carcinoma, and 41.7% in large cell carcinoma, respectively. The plat...

journal_title：Cancer

authors： Nakano T,Fujii J,Tamura S,Hada T,Higashino K

更新日期：1986-10-15 00:00:00

abstract：:Carcinoembryonic antigen (CEA) was measured in 147 patients at diagnosis of small cell lung cancer; 17% of patients with limited disease and 51% with extensive disease had an abnormal CEA level (greater than 10 ng/ml). The median level was higher in extensive than in limited disease (11 ng/ml and 5.8 ng/ml, respective...

journal_title：Cancer

authors： Laberge F,Fritsche HA,Umsawasdi T,Carr DT,Welch S,Murphy WK,Chiuten DF,Dhingra HM,Farha P,Spitzer G

更新日期：1987-06-15 00:00:00

abstract：:Molecular characterization of hepatocellular carcinoma (HCC) has greatly improved our understanding of disease pathogenesis. Mutational analysis, RNA and microRNA expression profiling, and epigenetic characterization have revealed common aberrations in oncogenes and tumor suppressors that correlate with disease biolog...

journal_title：Cancer

authors： Erstad DJ,Fuchs BC,Tanabe KK

更新日期：2018-08-01 00:00:00

abstract：:A 55-year-old man is reported who initially developed chronic lymphocytic leukemia. Seven years later, after chemotherapy with chlorambucil, chronic myelogenous leukemia was diagnosed in addition to the chronic lymphocytic leukemia. Four previously reported cases with the same sequence of events are reviewed as well a...

journal_title：Cancer

authors： Schreiber ZA,Axelrod MR,Abebe LS

更新日期：1984-08-15 00:00:00

abstract：BACKGROUND:The high recurrence rate of hepatocellular carcinoma (HCC) determines the long-term prognosis for patients with HCC. In the current study, the authors tested the effects of menatetrenone, a vitamin K2 analog, on recurrent HCC and survival after curative treatment. METHODS:Sixty-one patients who were diagnos...

journal_title：Cancer

authors： Mizuta T,Ozaki I,Eguchi Y,Yasutake T,Kawazoe S,Fujimoto K,Yamamoto K

更新日期：2006-02-15 00:00:00

abstract：:In 1963 an electron beam became available, making irradiation of the chest wall technically easy. In addition to peripheral lymphatic irradiation in patients with positive axillary nodes and/or the tumor in the inner quadrants or centrally located, patients with tumor larger than 5 cm or with grave signs and/or a sign...

journal_title：Cancer

authors： Tapley ND,Spanos WJ Jr,Fletcher GH,Montague ED,Schell S,Oswald MJ

更新日期：1982-03-15 00:00:00

abstract：BACKGROUND:Cancer of the male breast (MBC) is rare, accounting for less than 1% of cancer in males and representing less than 1% of all breast cancers. Reports of abnormalities in the expression of the tumor suppressor gene p53 in MBC have been few. METHODS:To assess the expression and mutations of the p53 gene, 35 pa...

journal_title：Cancer

authors： Anelli A,Anelli TF,Youngson B,Rosen PP,Borgen PI

更新日期：1995-05-01 00:00:00

abstract：BACKGROUND:DNA flow cytometry of hepatocellular carcinoma (HCC) cells has been investigated in many studies, but, to the best of our knowledge, there are no data on DNA analysis of cirrhotic parenchyma around the HCC. In this study, cell kinetics and ploidy of parenchymal cells around HCC were performed to ascertain if...

journal_title：Cancer

authors： Ruà S,Comino A,Fruttero A,Torchio P,Bouzari H,Taraglio S,Torchio B,Capussotti L

更新日期：1996-09-15 00:00:00

abstract：:The effect of cis-diamminedichloroplatinum II (DDP) and ionizing radiation on human bladder transitional cell carcinoma (TCC) was evaluated in nude mouse-grown human tumors following administration of single-agent and combination treatment. Combination of DDP and radiation resulted in accelerated tumor regression and ...

journal_title：Cancer

authors： Kyriazis AP,Yagoda A,Kereiakes JG,Kyriazis AA,Whitmore WF Jr

更新日期：1983-08-01 00:00:00

abstract：BACKGROUND:Brain metastases from soft tissue sarcoma (STS) are uncommon. To the authors' knowledge limited information is available regarding the influence of the initial STS site, the significance of parenchymal versus leptomeningeal metastases, and the role of surgical resection. METHODS:STS patients evaluated betwe...

journal_title：Cancer

authors： Espat NJ,Bilsky M,Lewis JJ,Leung D,Brennan MF

更新日期：2002-05-15 00:00:00

abstract：BACKGROUND:Several studies have demonstrated that abnormal levels of nuclear matrix protein 22 (NMP22) are associated with bladder cancer and have led to the approval of NMP22 as a urinary biomarker by the US Food and Drug Administration. Nonetheless, the clinical significance of NMP22 remains unclear. The objective of...

journal_title：Cancer

authors： Shariat SF,Savage C,Chromecki TF,Sun M,Scherr DS,Lee RK,Lughezzani G,Remzi M,Marberger MJ,Karakiewicz PI,Vickers AJ

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND:The focus on noncancer causes of death in patients with breast cancer (BC) remains superficial. The objective of the current study was to assess and quantify causes of death after BC diagnosis. METHODS:In total, 754,270 women with BC in the United States who were diagnosed during 2000 through 2015 and retri...

journal_title：Cancer

authors： Afifi AM,Saad AM,Al-Husseini MJ,Elmehrath AO,Northfelt DW,Sonbol MB

更新日期：2020-04-01 00:00:00

abstract：BACKGROUND:Despite the recognition of ionizing radiation as a causal risk factor for a variety of solid tumors (including brain tumors), to date, such an association with pituitary adenoma (PA) has not been demonstrated. METHODS:To evaluate a possible association between past exposure to radiation and the occurrence o...

journal_title：Cancer

authors： Juven Y,Sadetzki S

更新日期：2002-07-15 00:00:00

abstract：BACKGROUND:Patients who travel a long distance (≥50 miles) for cancer care have improved outcomes. However, to the authors' knowledge, the prevalence of long travel distances for treatment by patients with head and neck squamous cell carcinoma (HNSCC), and the effect of travel distance on overall survival (OS), remains...

journal_title：Cancer

authors： Graboyes EM,Ellis MA,Li H,Kaczmar JM,Sharma AK,Lentsch EJ,Day TA,Hughes Halbert C

更新日期：2018-08-01 00:00:00

abstract：BACKGROUND:The first step of colorectal carcinoma spread depends on the ability of the tumor cells to degrade and invade the extracellular matrix (ECM). The objectives of the current study were to evaluate the serum pattern of laminin, C-terminal peptide of Type I (PIP), and N-terminal peptide of Type III (PIIIP) proco...

journal_title：Cancer

authors： Plebani M,Basso D,Roveroni G,De Paoli M,Galeotti F,Corsini A

更新日期：1997-04-01 00:00:00

abstract：:Cancer is the second most common cause of death among those aged > or =65 years, and is a major cause of morbidity. There is some evidence that screening, by detecting precancerous lesions in asymptomatic patients, is effective in reducing cancer-related morbidity and mortality among older men and women. The objective...

journal_title：Cancer

authors： Sheinfeld Gorin S,Gauthier J,Hay J,Miles A,Wardle J

更新日期：2008-12-15 00:00:00

abstract：:The effects of radiotherapy on immune status in patients with localized carcinoma of the cervix have been assessed serially up to 5 years remission by a wide range of methods. Neutrophil function and serum immunoglobulins were essentially normal throughout. Peripheral blood neutrophil and lymphocyte counts and the pro...

journal_title：Cancer

authors： Hancock BW,Bruce L,Whitham MD,Ward AM

更新日期：1984-02-15 00:00:00

abstract：BACKGROUND:Optimal treatment of human immunodeficiency virus (HIV)-associated non-Hodgkin lymphoma (NHL) has yet to be defined, because chemotherapy could exacerbate immunodeficiency, with subsequent adverse effects for patients. METHODS:The authors investigated the feasibility of an intensive chemotherapy regimen for...

journal_title：Cancer

authors： Costello RT,Zerazhi H,Charbonnier A,de Colella JM,Alzieu C,Poizot-Martin I,Cohen R,Bardou VJ,Xerri L,Olive D,Nezri M,Lepeu G,Gastaut JA

更新日期：2004-02-15 00:00:00