Use of carcinoembryonic antigen in small cell lung cancer. Prognostic value and relation to the clinical course 1.

abstract：:An astroblastoma in the cerebrum was investigated with the electron microscope. A distinctive feature of the tumor was the radial arrangement of astrocytic cells around the blood vessels. The blood vessels in the tumor commonly exhibited fenestrated endothelial cells. The endothelium was generally surrounded by lamell...

journal_title：Cancer

authors： Kubota T,Hirano A,Sato K,Yamamoto S

更新日期：1985-02-15 00:00:00

abstract：:This report is based on 903 patients with resections for gastric carcinoma between October 1957, and July 1969, entered in controlled trials of adjuvant therapy with Thio-TEPA and FUDR. Neither Thio-TEPA nor FUDR, as administered, prolonged survival. The extent of disease at the time of curative surgery is related to ...

journal_title：Cancer

authors： Serlin O,Keehn RJ,Higgins GA Jr,Harrower HW,Mendeloff GL

更新日期：1977-09-01 00:00:00

abstract：BACKGROUND:Pretreatment serum prostate specific antigen (PSA) level is a powerful prognostic factor for clinically localized prostate carcinoma. The traditional prognostic factors, T classification and Gleason score, appear to have been relegated to a minor position. This study was conducted to evaluate the relative pr...

journal_title：Cancer

authors： Zagars GK,Pollack A,von Eschenbach AC

更新日期：1997-04-01 00:00:00

abstract：BACKGROUND:The objective of this article was to report the results from a randomized clinical trial comparing intensity-modulated radiotherapy (IMRT) with 3-dimensonal conformal radiotherapy (3DCRT) for the treatment of prostate cancer on a hypofractionated schedule. METHODS:The authors randomly assigned 215 men who h...

journal_title：Cancer

authors： Viani GA,Viana BS,Martin JE,Rossi BT,Zuliani G,Stefano EJ

更新日期：2016-07-01 00:00:00

abstract：:Three patients with biopsy-proven lentigo maligna were treated with topical 5-fluorouracil. Treatment consisted of twice daily application of 5% 5-fluorouracil cream for 13, 6, and 9 weeks, respectively. Two patients demonstrated presence of invasive melanoma; in one the melanoma was evident before chemotherapy, and i...

journal_title：Cancer

authors： Litwin MS,Krementz ET,Mansell PW,Reed RJ

更新日期：1975-03-01 00:00:00

abstract：:A short-term differential staining cytotoxicity (DiSC) assay was used to assess the sensitivity of tumor cells in vitro from patients with chronic lymphocytic leukemia (CLL) and non-Hodgkin's lymphoma to various cytotoxic drugs. The results have been correlated with drug sensitivities of the tumors in vivo. The chemos...

journal_title：Cancer

authors： Bird MC,Bosanquet AG,Forskitt S,Gilby ED

更新日期：1988-03-15 00:00:00

abstract：BACKGROUND:Theoretical considerations have raised the suspicion that transurethral resection of the prostate (TURP) may increase the risk of developing prostate cancer in clinically benign prostate glands. Previous studies have not shown an increased risk among men who had undergone TURP for benign prostatic hyperplasi...

journal_title：Cancer

authors： Hammarsten J,Andersson S,Holmén A,Högstedt B,Peeker R

更新日期：1994-10-15 00:00:00

abstract：BACKGROUND:Soft tissue sarcomas of the hand and foot present unique management challenges. The purpose of the current study study was to determine oncologic outcome, particularly with respect to factors affecting local recurrence, distant recurrence, and disease-specific survival. METHODS:A retrospective study was per...

journal_title：Cancer

authors： Lin PP,Guzel VB,Pisters PW,Zagars GK,Weber KL,Feig BW,Pollock RE,Yasko AW

更新日期：2002-08-15 00:00:00

abstract：:Breast cancer is the most common cancer among American women. Because metastatic breast cancer is an incurable disease, efforts to decrease breast cancer mortality have focused on early detection and improved treatment. Identification and analysis of a specific genetic susceptibility could permit detection of suscepti...

journal_title：Cancer

authors： Skolnick MH,Cannon-Albright LA

更新日期：1992-09-15 00:00:00

abstract：BACKGROUND:The objective of this study was to estimate the time to treatment failure and survival rate of the three-drug combination of doxorubicin, cisplatin, and ifosfamide as primary and postoperative, adjunctive treatment for teenagers and adults with osteosarcoma (OS). METHODS:Sixty-three eligible patients with n...

journal_title：Cancer

authors： Zalupski MM,Rankin C,Ryan JR,Lucas DR,Muler J,Lanier KS,Budd GT,Biermann JS,Meyers FJ,Antman K

更新日期：2004-02-15 00:00:00

abstract：BACKGROUND:Soft tissue sarcomas (STSs) are heterogeneous neoplasms that have variable clinical outcome. Several clinical parameters and few molecular markers, including Ki-67 proliferative index, have been shown to correlate with patient prognosis. To the authors' knowledge, no definitive report exists to identify one ...

journal_title：Cancer

authors： Hoos A,Stojadinovic A,Mastorides S,Urist MJ,Polsky D,Di Como CJ,Brennan MF,Cordon-Cardo C

更新日期：2001-08-15 00:00:00

abstract：BACKGROUND:Knowledge of the expression of the galectins in human colon carcinomas is mainly restricted to galectin-3 and, to a lesser extent, galectin-1. The current study analyzed the prognostic values contributed by galectin-1, galectin-3, galectin-4, and galectin-8 in cases of colon carcinoma. METHODS:The authors s...

journal_title：Cancer

authors： Nagy N,Legendre H,Engels O,André S,Kaltner H,Wasano K,Zick Y,Pector JC,Decaestecker C,Gabius HJ,Salmon I,Kiss R

更新日期：2003-04-15 00:00:00

abstract：BACKGROUND:At the time of diagnosis of colorectal carcinoma, 2-3% of patients are likely to be harboring brain metastases, and another 10% of patients will develop brain lesions during the course of their disease. The purpose of this study was to examine the clinical course of a group of patients with metastatic brain ...

journal_title：Cancer

authors： Wroński M,Arbit E

更新日期：1999-04-15 00:00:00

abstract：:Twenty-one patients with bilateral Wilms' tumor are reviewed and the details of diagnosis, therapy, and survival presented. All patients had an abdominal mass at the time of diagnosis. Associated findings included hypertension, aniridia, and genitourinary anomalies. Favorable histologic features were found in all simu...

journal_title：Cancer

authors： Asch MJ,Siegel S,White L,Fonkalsrud E,Hays D,Isaacs H

更新日期：1985-11-15 00:00:00

abstract：BACKGROUND:The aim of this study was to determine and compare the added prognostic value of screening tools, geriatric assessment (GA) components, and GA summaries to clinical information for overall survival (OS) in older patients with cancer. METHODS:A screening and a 10-item GA were systematically performed in pati...

journal_title：Cancer

authors： Kenis C,Baitar A,Decoster L,De Grève J,Lobelle JP,Flamaing J,Milisen K,Wildiers H

更新日期：2018-09-15 00:00:00

abstract：:Multiple independent tumors were identified in specimens from 117 of 234 prostatectomies for clinical adenocarcinoma; there were 266 incidental cancers in these 117 prostates. The clinically detected carcinoma was the largest (or only) tumor in all 202 Stage B cases. However, among 32 Stage A cases (detection by trans...

journal_title：Cancer

authors： Villers A,McNeal JE,Freiha FS,Stamey TA

更新日期：1992-11-01 00:00:00

abstract：:The treatment of locally advanced rectal cancer (LARC) has benefited from improved surgical techniques and from the implementation of neoadjuvant chemoradiotherapy (CRT), which have markedly decreased the rates of local recurrence. However, distant metastatic disease remains the most significant cause of death for the...

journal_title：Cancer

authors： Ludmir EB,Palta M,Willett CG,Czito BG

更新日期：2017-05-01 00:00:00

abstract：BACKGROUND:Ewing sarcoma family of tumors (ESFTs) are the second most common bone tumor, that most often affects persons ages 3-40 years. The ESFTs rely on signaling through the insulin-like growth factor-1 receptor (IGF-1R) for growth and transformation. The current studies were performed to determine the levels of IG...

journal_title：Cancer

authors： Toretsky JA,Steinberg SM,Thakar M,Counts D,Pironis B,Parente C,Eskenazi A,Helman L,Wexler LH

更新日期：2001-12-01 00:00:00

abstract：:Prolymphocytic leukemia (PL) is a clinically distinct leukemic disorder. Cytochemical and surface marker characteristics help to differentiate PL from other types of leukemia, including chronic lymphocytic leukemia (CLL). In contrast to patients with CLL, those with PL frequently require early therapeutic intervention...

journal_title：Cancer

authors： Taylor HG,Butler WM,Rhoads J,Karcher DS,Detrick-Hooks B

更新日期：1982-04-15 00:00:00

abstract：BACKGROUND:Gene expression profiling should be applicable to needle biopsy samples if microarray technology is to become practically useful for clinical research or management of breast carcinoma. This study compared gene expression profiles derived from fine-needle aspiration biopsy (FNAB) and from core needle biopsy ...

journal_title：Cancer

authors： Symmans WF,Ayers M,Clark EA,Stec J,Hess KR,Sneige N,Buchholz TA,Krishnamurthy S,Ibrahim NK,Buzdar AU,Theriault RL,Rosales MF,Thomas ES,Gwyn KM,Green MC,Syed AR,Hortobagyi GN,Pusztai L

更新日期：2003-06-15 00:00:00

abstract：:A prospective randomized trial by CALGB examined the relative value of four chemotherapy regimens in 537 patients with stage III B and IV Hodgkin's disease. A new combination BOPP, derived by substitution of BCNU for nitrogen mustard in the MOPP regimen, was compared to MOPP and to two 3-drug regimens, derived by remo...

journal_title：Cancer

authors： Nissen NI,Pajak TF,Glidewell O,Pedersen-Bjergaard J,Stutzman L,Falkson G,Cuttner J,Blom J,Leone L,Sawitsky A,Coleman M,Haurani F,Spurr CL,Harley JB,Seligman B,Cornell C Jr,Henry P,Senn HJ,Brunner K,Martz G,Maurice

更新日期：1979-01-01 00:00:00

abstract：BACKGROUND:Partial splenic embolization (PSE) has been used to improve hematologic parameters related to hypersplenism. The purpose of this study was to review our institutional experience with PSE for cancer patients with thrombocytopenia because of splenic sequestration precluding the administration of systemic thera...

journal_title：Cancer

authors： Kauffman CR,Mahvash A,Kopetz S,Wolff RA,Ensor J,Wallace MJ

更新日期：2008-05-15 00:00:00

abstract：BACKGROUND:Heparanase up-regulation has been correlated with reduced postoperative survival in various cancers. METHODS:Heparanase expression was analyzed in 60 consenting tongue (mobile) cancer patients by means of immunohistochemistry. Heparanase levels were also analyzed in the saliva of both healthy controls and t...

journal_title：Cancer

authors： Nagler R,Ben-Izhak O,Cohen-Kaplan V,Shafat I,Vlodavsky I,Akrish S,Ilan N

更新日期：2007-12-15 00:00:00

abstract：:The authors describe the results of a hospital-based incident case-control study of lung cancer conducted in a high-risk region of southern Louisiana from January 1979 through April 1982. Dietary intake of carotene, retinol, and vitamin C was estimated from food frequency questionnaires administered to 1253 cases and ...

journal_title：Cancer

authors： Fontham ET,Pickle LW,Haenszel W,Correa P,Lin YP,Falk RT

更新日期：1988-11-15 00:00:00

abstract：:Necropsy and clinical data show that primary hepatocellular carcinoma (PHC) is the commonest cancer among the Senoi (a Malaysian aboringine group). The other aboringine tribes do not appear to have this high predilection for liver cancer. In the necropsy series, PHS was present in 10 out of 22 Senoi patients with cirr...

journal_title：Cancer

authors： Sumithran E,Prathap K

更新日期：1977-10-01 00:00:00

abstract：BACKGROUND:The causal relation between high-risk human papillomavirus (HPV) and cervical cancer and its precursor lesions has led to the use of sensitive HPV molecular tests for screening. This study examined the impact of the baseline HPV status on the future risk of cervical intraepithelial neoplasia grade 2 or worse...

journal_title：Cancer

authors： Fröberg M,Östensson E,Belkić K,Oštrbenk A,Poljak M,Mints M,Arbyn M,Andersson S

更新日期：2019-01-15 00:00:00

abstract：:Two children with Wilms' tumor and prior thoracic radiation developed congestive heart failure at cumulative adriamycin doses of 350 mg/m2 and 400 mg/m2. Details of these two cases and a summary of previously reported adriamycin cardiotoxicity in children are presented. Dose recommendations and predictive tests are di...

journal_title：Cancer

authors： Prout MN,Richards MJ,Chung KJ,Joo P,Davis HL Jr

更新日期：1977-01-01 00:00:00

abstract：:Doxorubicin is an effective antineoplastic agent, but it frequently causes dose-related cardiotoxic effects. Because the atrial natriuretic peptide (ANP) level is elevated in children with heart defects, the authors measured the ANP levels in children to determine whether ANP might serve as a simple diagnostic indicat...

journal_title：Cancer

authors： Bauch M,Ester A,Kimura B,Victorica BE,Kedar A,Phillips MI

更新日期：1992-03-15 00:00:00

abstract：:Research trends on quality of life outcomes for cancer survivors are discussed. Epidemiologic data indicate that female cancer survivors, coming primarily from patient groups with gynecologic, breast, and colorectal cancers, will outnumber male survivors 3 to 1. Male survivors will come from the ranks of patient group...

journal_title：Cancer

authors： Andersen BL

更新日期：1994-08-15 00:00:00

abstract：BACKGROUND:Chemotherapy is known to cure a small minority of patients with acute myeloid leukemia (AML). Less is known about the risk of such patients developing subsequent cancers or about their ability to return to work. METHODS:The authors analyzed outcomes among 1892 patients who received treatment for newly diagn...

journal_title：Cancer

authors： Estey E,deLima M,Strom S,Pierce S,Freireich EJ,Keating MJ

更新日期：1997-12-01 00:00:00