The added value of geriatric screening and assessment for predicting overall survival in older patients with cancer.

abstract：BACKGROUND:The association of Langerhans cell histiocytosis (LCH) with a malignant neoplasm is rare and generally has been the subject of isolated case reports. METHODS:A recent case of LCH seen at the University of Minnesota in combination with acute lymphoblastic leukemia led the authors to review their own charts f...

journal_title：Cancer

authors： Egeler RM,Neglia JP,Puccetti DM,Brennan CA,Nesbit ME

更新日期：1993-02-01 00:00:00

abstract：:The adolescent and young adult (AYA) oncology population has seen inferior progress in cancer survival compared with younger children and older adults over the past 25 years. Previously, AYAs had the best survival rates due to the prevalence of highly curable diseases including Hodgkin lymphoma and germ cell tumors, y...

journal_title：Cancer

authors： Burke ME,Albritton K,Marina N

更新日期：2007-12-01 00:00:00

abstract：BACKGROUND:The role of adjuvant therapy in the management of patients with malignant mixed Müllerian tumors (MMMT) of the uterus has not been defined. The outcome of planned multimodality therapy for patients with apparent early stage disease was assessed. METHODS:A pilot study was performed on 38 patients with clinic...

journal_title：Cancer

authors： Manolitsas TP,Wain GV,Williams KE,Freidlander M,Hacker NF

更新日期：2001-04-15 00:00:00

abstract：:Lymphoid cells from two patients with hand-mirror variant of acute lymphoblastic leukemia (ALL) were studied with various monoclonal antibodies in attempts to determine their derivation and differentiation. The predominant feature of the malignant bone marrow cells was strong reactivity with antibody 3A1, which stains...

journal_title：Cancer

authors： Gramatzki M,Strong DM,Duval-Arnould B,Morstyn G,Schumacher HR

更新日期：1985-01-01 00:00:00

abstract：:An infant who presented with a thigh mass and coagulopathy was found to have a hemangioendothelioma. The tumor rapidly enlarged despite accepted therapeutic modalities, and the child died after a sudden cardiac arrest. Postmortem examination revealed a highly invasive tumor mass that had infiltrated the bowel and invo...

journal_title：Cancer

authors： Weinblatt ME,Kahn E,Kochen JA

更新日期：1984-11-15 00:00:00

abstract：:Levamisole, used in vitro at therapeutic concentrations, was found able to restore the defective Fc-receptor activity of cancer patient neutrophils. In addition, the drug prevented the inhibition of normal neutrophils Fc-receptor function by cancer patient sera. The neutrophil Fc-receptor function was also restored in...

journal_title：Cancer

authors： Patrone F,Dallegri F,Pistoia V,Ghio R,Sacchetti C

更新日期：1985-04-15 00:00:00

abstract：:Most patients with colorectal carcinoma undergo attempts at curative surgery. However, some present with metastatic disease and many others ultimately relapse. Most recurrences of colorectal cancer are not resectable and require nonsurgical approaches such as chemotherapy and radiation therapy directed against local r...

journal_title：Cancer

authors： Vaughn DJ,Haller DG

更新日期：1993-06-15 00:00:00

abstract：BACKGROUND:Cyclins, cyclin dependent kinases (cdks), and their inhibitors act in combination to regulate progression through the cell cycle and often are dysregulated in carcinoma. The authors hypothesized that cyclin E plays an important role in ovarian carcinogenesis and that its overexpression may be an indicator of...

journal_title：Cancer

authors： Rosen DG,Yang G,Deavers MT,Malpica A,Kavanagh JJ,Mills GB,Liu J

更新日期：2006-05-01 00:00:00

abstract：BACKGROUND:Five-year survival rates after resection of liver metastases from colorectal carcinoma are close to 25%. Recurrences occur in two-thirds of the patients after surgery. Selection of patients likely to benefit from surgery remains controversial and subjective. METHODS:Data from 1568 patients with resected liv...

journal_title：Cancer

authors： Nordlinger B,Guiguet M,Vaillant JC,Balladur P,Boudjema K,Bachellier P,Jaeck D

更新日期：1996-04-01 00:00:00

abstract：BACKGROUND:Several of the large studies addressing prognosis and survival from hepatocellular carcinoma (HCC) have been from Europe and Asia, but only a few have emanated from North America. Survival statistics from other parts of the world may not be applicable to the North American population because of etiologic, de...

journal_title：Cancer

authors： Nzeako UC,Goodman ZD,Ishak KG

更新日期：1995-08-15 00:00:00

abstract：:Disulfiram (tetraethylthiuram disulfide, Antabuse) and sodium diethyldithiocarbamate, when added to the diet, inhibit 1,2-dimethylhydrazine (DMH)-induced neoplasia of the large bowel in female CF1 mice. Ethylene bis(dithiocarbamato)manganese (Maneb) and bis(ethylxanthogen), two pesticides with structural similarities ...

journal_title：Cancer

authors： Wattenberg LW,Lam LK,Fladmoe AV,Borchert P

更新日期：1977-11-01 00:00:00

abstract：BACKGROUND:The purpose was to compare the differential expression of Survivin in normal bladder tissue, bladder transitional cell carcinoma (TCC) of different stages, and to determine whether expression of Survivin is associated with TCC clinical outcomes. METHODS:Immunohistochemical staining for Survivin was carried ...

journal_title：Cancer

authors： Shariat SF,Ashfaq R,Karakiewicz PI,Saeedi O,Sagalowsky AI,Lotan Y

更新日期：2007-03-15 00:00:00

abstract：:The authors report a case of leiomyosarcoma in the mediastinum presenting with superior vena cava obstruction, and also demonstrate the aggressive nature of this tumor in spite of radiotherapy. Where technically feasible, surgery appears to be the treatment of choice. The pathologic and electron microscopic features o...

journal_title：Cancer

authors： Sunderrajan EV,Luger AM,Rosenholtz MJ,Maltby JD

更新日期：1984-06-01 00:00:00

abstract：:Growth kinetics of 102 breast carcinomas were studied by immunohistochemical analysis with the monoclonal antibody Ki-67, which reacts with a nuclear antigen in proliferating cells. The results were correlated with ploidy and S-phase fraction (SPF) analyzed by DNA flow cytometric study and with mitotic count analyzed ...

journal_title：Cancer

authors： Isola JJ,Helin HJ,Helle MJ,Kallioniemi OP

更新日期：1990-03-01 00:00:00

abstract：:A 42-year-old woman developed lower extremity weakness and sensory loss 1 year after external and intracavitary radiotherapy for Stage IB carcinoma of cervix. She has been followed for 5 years posttreatment, and the neurologic abnormalities have persisted, but no evidence of recurrent carcinoma has been found. We beli...

journal_title：Cancer

authors： Stryker JA,Sommerville K,Perez R,Velkley DE

更新日期：1990-10-01 00:00:00

abstract：BACKGROUND:Although protein expressions of glucocorticoid receptor (GR), estrogen receptors (ERα and ERβ), progesterone receptor A (PgR-A), and androgen receptor (AR) were shown to play roles in the growth and differentiation of normal thymus and thymic tumors, to the authors' knowledge their association with patient c...

journal_title：Cancer

authors： Mimae T,Tsuta K,Takahashi F,Yoshida A,Kondo T,Murakami Y,Okada M,Takeuchi M,Asamura H,Tsuda H

更新日期：2011-10-01 00:00:00

abstract：:There is a growing body of basic science and epidemiologic evidence to support a research thrust to determine whether several natural or synthetic agents, given alone or together, can lower cancer incidence. Candidate agents include analogs of vitamin A and the vitamin A precursor, beta-carotene, vitamins C and E, and...

journal_title：Cancer

authors： Malone WF,Kelloff GJ,Pierson H,Greenwald P

更新日期：1987-08-01 00:00:00

abstract：BACKGROUND:An increased understanding of the biology of prostate carcinoma has led to the clinical evaluation of mechanism-based and targeted therapies. Modulating the immune system has been pursued through the use of both active and passive immunity as well as the ex vivo genetic manipulation of effector cells. A vari...

journal_title：Cancer

authors： Morris MJ,Scher HI

更新日期：2000-09-15 00:00:00

abstract：BACKGROUND:To describe continuing care and rehabilitation needs of cancer patients, a longitudinal design (6 months) was performed among patients 50 years of age and older with solid tumors. The study examined how age, type of treatment, site of cancer, and symptom experience affect physical functioning and their menta...

journal_title：Cancer

authors： Given CW,Given BA,Stommel M

更新日期：1994-10-01 00:00:00

abstract：:BALB/c mice were hyperimmunized with ACHN (ATCC CRL 1611, American Type Culture Collection, Rockville, Maryland), a stable in vitro cell line derived from a malignant pleural effusion in a 22-year-old man with renal cell carcinoma. The hyperimmune spleen cells were fused with NS-1 murine myeloma cells using polyethyle...

journal_title：Cancer

authors： Kochevar J

更新日期：1987-06-15 00:00:00

abstract：:Increasing scientific attention is focused on the gut-brain axis, including the ability of the gastrointestinal (GI) tract to modulate central nervous system function. Changes in the intestinal microbiome can influence affective-like behavior, cognitive performance, fatigue, and sleep in rodents and humans. Patients w...

journal_title：Cancer

authors： Jordan KR,Loman BR,Bailey MT,Pyter LM

更新日期：2018-10-15 00:00:00

abstract：BACKGROUND:Recombinant tumor necrosis factor-alpha (rTNF-alpha) is a highly potential antineoplastic agent. However, its systemic administration in humans has resulted in a life-threatening septic shock-like syndrome, and its use has been abandoned. The administration of high dose rTNF-alpha and melphalan via isolated ...

journal_title：Cancer

authors： Gutman M,Inbar M,Lev-Shlush D,Abu-Abid S,Mozes M,Chaitchik S,Meller I,Klausner JM

更新日期：1997-03-15 00:00:00

abstract：:From 1977, 29 patients with inoperable non-small cell lung carcinoma due to locally far-advanced disease underwent lung resection after receiving two to eight courses of chemotherapy. After the surgery was performed, three additional courses of chemotherapy were given. The overall median survival from onset of the che...

journal_title：Cancer

authors： Takita H,Regal AM,Antkowiak JG,Rao UN,Botsoglou NK,Lane WW

更新日期：1986-02-01 00:00:00

abstract：BACKGROUND:The objective of this study was to assess the rate and possible reasons for false-negative (FN) reflex human papillomavirus (HPV)-DNA tests. METHODS:The authors reviewed all ThinPrep cervical specimens that were submitted for reflex HPV-DNA testing using the Digene Hybrid Capture II (HC2) method from Januar...

journal_title：Cancer

authors： Eltoum IA,Chhieng DC,Crowe DR,Roberson J,Jin G,Broker TR

更新日期：2007-06-25 00:00:00

abstract：BACKGROUND:Tobacco assessment and cessation support are not routinely included in cancer care. An automated tobacco assessment and cessation program was developed to increase the delivery of tobacco cessation support for cancer patients. METHODS:A structured tobacco assessment was incorporated into the electronic heal...

journal_title：Cancer

authors： Warren GW,Marshall JR,Cummings KM,Zevon MA,Reed R,Hysert P,Mahoney MC,Hyland AJ,Nwogu C,Demmy T,Dexter E,Kelly M,O'Connor RJ,Houstin T,Jenkins D,Germain P,Singh AK,Epstein J,Dobson Amato KA,Reid ME

更新日期：2014-02-15 00:00:00

abstract：BACKGROUND:Adenosquamous/squamous cell carcinoma of the gallbladder generally has been considered a lethal disease. The objective of this study was to clarify the effectiveness of resection for patients with adenosquamous/squamous cell carcinoma of the gallbladder. METHODS:Twenty-nine patients who underwent resection ...

journal_title：Cancer

authors： Oohashi Y,Shirai Y,Wakai T,Nagakura S,Watanabe H,Hatakeyama K

更新日期：2002-06-01 00:00:00

abstract：BACKGROUND:Because patients with germ cell tumors expect an additional life span of around 50 years after successful treatment, attention is now focused on potential long term toxicity. Limited data are available on Leydig cell function in long term survivors. METHODS:The authors measured testosterone, sex hormone bin...

journal_title：Cancer

authors： Gerl A,Mühlbayer D,Hansmann G,Mraz W,Hiddemann W

更新日期：2001-04-01 00:00:00

abstract：:One hundred nine cases of ovarian tumors of low malignant potential (borderline tumors) diagnosed at Stanford University Medical Center from 1958 to 1982 were reviewed. The patients ranged in age from 10 to 79 years (mean, 40.5 years). The histologic types and corresponding stages of these neoplasms were 73 serous (St...

journal_title：Cancer

authors： Bostwick DG,Tazelaar HD,Ballon SC,Hendrickson MR,Kempson RL

更新日期：1986-11-01 00:00:00

abstract：BACKGROUND:Studies of colorectal adenocarcinoma (CRC) indicate a higher mortality rate for African Americans compared with Caucasians in the United States. In the current study, the authors evaluated the racial differences in survival based on tumor location and pathologic stage between African-American patients and Ca...

journal_title：Cancer

authors： Alexander D,Chatla C,Funkhouser E,Meleth S,Grizzle WE,Manne U

更新日期：2004-07-01 00:00:00

abstract：:To test the hypothesis that there is a positive association between chronic alcoholism and carcinoma of the pancreas, the mortality experience of 1382 chronic alcoholics was studied. Analysis was limited to a comparison of observed and expected proportional mortality of different causes of death in the 894 whites who ...

journal_title：Cancer

authors： Monson RR,Lyon JL

更新日期：1975-09-01 00:00:00