Abstract:
:This report is based on 903 patients with resections for gastric carcinoma between October 1957, and July 1969, entered in controlled trials of adjuvant therapy with Thio-TEPA and FUDR. Neither Thio-TEPA nor FUDR, as administered, prolonged survival. The extent of disease at the time of curative surgery is related to survival for the first 36 months postoperatively. Involvement of lymph nodes, resection of the esophagus, and serosal penetration are predictive of recurrence up to 36 months. There appear to be three groups of patients: 1) Cured (26%); 2) Slowly growing tumor--23% (median survival, 25 months); and 3) Rapidly growing tumor--51% (median survival, eight months). The absence of blood-vessel invasion, lymphatic invasion, lymph-node involvement, and serosal penetration characterize those patients in Group A.
journal_name
Cancerjournal_title
Cancerauthors
Serlin O,Keehn RJ,Higgins GA Jr,Harrower HW,Mendeloff GLdoi
10.1002/1097-0142(197709)40:3<1318::aid-cncr282040subject
Has Abstractpub_date
1977-09-01 00:00:00pages
1318-29issue
3eissn
0008-543Xissn
1097-0142journal_volume
40pub_type
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