Association between mammographic parenchymal pattern classification and incidence of breast cancer.

Abstract:

:Wolfe has suggested that the mammographic parenchymal patterns can be used to identify a group with high incidence of breast cancer. To evaluate this claim, mammograms of women with breast cancer that was detected at the University of Michigan Breast Cancer Detection Demonstration Project have been classified and compared with a randomly selected control group from the same project. The basic mammographic classifications as defined by Wolfe were used with further refinements made in the DY and QDY groups. The mammographic classifications have been grouped according to the degree of density and age. For all ages combined, our dense classifications (DY1, DY2, DYC-, QDY2) show a higher incident rate, 22/1000,than the lucent classification (N1, P1, and QDY1),9/1000,(P less than .01), although not to the degree suggested by Wolfe. This difference is statistically significant (P less than .01); the higher risk is markedly increased for women under 50 years of age (P less than .005). After age 50 the higher risk associated with the dense breast seems to disappear (P less than .13). However, this might be a consequence of women who were in a dense classification at an earlier age who subsequently changed to a lucent classification later in life. Because the percentage of lucent breasts increases with age there is a higher absolute number of cancers (55%) in this group of women past 50; these women cannot be neglected in screening. Our results suggest the following guidelines for clinical evaluation: (1) Careful mammographic and clinical follow-up for any woman with a dense breast at any age. (2) Careful mammographic and clinical follow-up past 50 regardless of breast classification. (3) Women with lucent breasts under age 50 represent a low risk category and may not require as frequent a follow-up as the other mammographic types.

journal_name

Cancer

journal_title

Cancer

authors

Threatt B,Norbeck JM,Ullman NS,Kummer R,Roselle P

doi

10.1002/1097-0142(19800515)45:10<2550::aid-cncr282

subject

Has Abstract

pub_date

1980-05-15 00:00:00

pages

2550-6

issue

10

eissn

0008-543X

issn

1097-0142

journal_volume

45

pub_type

杂志文章

相关文献

CANCER文献大全
  • The added value of geriatric screening and assessment for predicting overall survival in older patients with cancer.

    abstract:BACKGROUND:The aim of this study was to determine and compare the added prognostic value of screening tools, geriatric assessment (GA) components, and GA summaries to clinical information for overall survival (OS) in older patients with cancer. METHODS:A screening and a 10-item GA were systematically performed in pati...

    journal_title:Cancer

    pub_type: 杂志文章,多中心研究

    doi:10.1002/cncr.31581

    authors: Kenis C,Baitar A,Decoster L,De Grève J,Lobelle JP,Flamaing J,Milisen K,Wildiers H

    更新日期:2018-09-15 00:00:00

  • The influence of histologic type on survival in non-Hodgkin's lymphoma.

    abstract::Histologic groups in 231 cases of malignant lymphoma were correlated with survival data at 100 months from the time of initiation of the study. Patients in the first two decades of life fared comparably with adults, but those over 60 years of age showed a poorer survival trend. Seven favorable and four unfavorable his...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19810615)47:12<2894::aid-cncr282

    authors: Barcos M,Herrmann R,Pickren JW,Naeher C,Han T,Stutzman L,Henderson ES

    更新日期:1981-06-15 00:00:00

  • Long survival in patients with acquired immune deficiency syndrome-related primary central nervous system lymphoma.

    abstract:BACKGROUND:Primary central nervous system lymphoma (PCNSL) is the most common brain tumor occurring in patients with acquired immune deficiency syndrome (AIDS). After diagnosis of PCNSL, the median survival time is 2-5 months with treatment with whole brain irradiation (WBI). METHODS:Four (of approximately 40) patient...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19940315)73:6<1728::aid-cncr2820

    authors: Chamberlain MC

    更新日期:1994-03-15 00:00:00

  • EphA2 overexpression is associated with angiogenesis in ovarian cancer.

    abstract:BACKGROUND:EphA2 is overexpressed in the majority of ovarian cancers and predicts poor clinical outcome. Based on EphA2's emerging role in angiogenesis, we hypothesized that tumors overexpressing EphA2 demonstrate greater microvessel density (MVD) and matrix metalloproteinase (MMP) expression. METHODS:After Institutio...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.22415

    authors: Lin YG,Han LY,Kamat AA,Merritt WM,Landen CN,Deavers MT,Fletcher MS,Urbauer DL,Kinch MS,Sood AK

    更新日期:2007-01-15 00:00:00

  • A tool for predicting breast carcinoma mortality in women who do not receive adjuvant therapy.

    abstract:BACKGROUND:Among the several proposed risk classification schemes for predicting survival in women with breast carcinoma, one of the most commonly used is the Nottingham Prognostic Index (NPI). The goal of the current study was to use a continuous prognostic model (similar to those that have already been demonstrated t...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.20635

    authors: Kattan MW,Giri D,Panageas KS,Hummer A,Cranor M,Van Zee KJ,Hudis CA,Norton L,Borgen PI,Tan LK

    更新日期:2004-12-01 00:00:00

  • Evaluation of cell proliferation in breast carcinoma. Comparison of Ki-67 immunohistochemical study, DNA flow cytometric analysis, and mitotic count.

    abstract::Growth kinetics of 102 breast carcinomas were studied by immunohistochemical analysis with the monoclonal antibody Ki-67, which reacts with a nuclear antigen in proliferating cells. The results were correlated with ploidy and S-phase fraction (SPF) analyzed by DNA flow cytometric study and with mitotic count analyzed ...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19900301)65:5<1180::aid-cncr2820

    authors: Isola JJ,Helin HJ,Helle MJ,Kallioniemi OP

    更新日期:1990-03-01 00:00:00

  • Commonly cited website quality criteria are not effective at identifying inaccurate online information about breast cancer.

    abstract:BACKGROUND:Consumers increasingly consult the Internet for breast cancer information. Concerned about accuracy, multiple organizations developed quality criteria for online content. However, the effectiveness of these tools is unknown. The authors determined whether existing quality criteria can identify inaccurate bre...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.23308

    authors: Bernstam EV,Walji MF,Sagaram S,Sagaram D,Johnson CW,Meric-Bernstam F

    更新日期:2008-03-15 00:00:00

  • Contemporary prevalence of pretreatment urinary, sexual, hormonal, and bowel dysfunction: Defining the population at risk for harms of prostate cancer treatment.

    abstract:BACKGROUND:The authors investigated the prevalence of pretreatment urinary, sexual, hormonal, and bowel dysfunction in a contemporary, population-based prostate cancer cohort. They also explored the associations between baseline function and age, comorbidity, and timing of baseline survey completion with respect to tre...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.28563

    authors: Resnick MJ,Barocas DA,Morgans AK,Phillips SE,Chen VW,Cooperberg MR,Goodman M,Greenfield S,Hamilton AS,Hoffman KE,Kaplan SH,Paddock LE,Stroup AM,Wu XC,Koyama T,Penson DF

    更新日期:2014-04-15 00:00:00

  • Alternating noncross-resistant combination chemotherapy and active nonspecific immunotherapy with BCG or MER-BCG for advanced breast carcinoma.

    abstract::One hundred fifty-six evaluable patients with metastatic breast cancer were treated with vincristine, Adriamycin and cyclophosphamide alternating at fixed intervals with 5-FU and methotrexate. Immunotherapy with BCG or MER-BCG was administered to all patients in two consecutive treatment programs. Overall objective re...

    journal_title:Cancer

    pub_type: 临床试验,杂志文章

    doi:10.1002/1097-0142(19800215)45:4<742::aid-cncr28204

    authors: Blumenschein GR,Hortobagyi GN,Richman SP,Gutterman JU,Tashima CK,Buzdar AU,Burgess MA,Livingston RB,Hersh EM

    更新日期:1980-02-15 00:00:00

  • Basaloid squamous cell carcinoma of floor of mouth.

    abstract:BACKGROUND:Only five cases of basaloid squamous cell carcinoma (BSCC), a rare tumor of head and neck, have been reported to involve the floor of mouth. METHODS:Clinicopathologic and immunohistochemical features of eight BSCC of floor of mouth were studied to evaluate the significance of the basaloid features. RESULTS...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19931015)72:8<2299::aid-cncr2820

    authors: Coppola D,Catalano E,Tang CK,Elfenbein IB,Harwick R,Mohr R

    更新日期:1993-10-15 00:00:00

  • Nutrition and diet in the etiology of endometrial cancer.

    abstract::The risk of endometrial cancer in relation to nutrition and frequency of consumption of a few selected dietary items was evaluated in a case-control study of 206 patients with endometrial cancer and 206 control subjects with acute conditions unrelated to any of the established or potential risk factors for endometrial...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19860315)57:6<1248::aid-cncr2820

    authors: La Vecchia C,Decarli A,Fasoli M,Gentile A

    更新日期:1986-03-15 00:00:00

  • Immunotherapy with levamisole: early decrease of cAMP levels in lymphocytes from treated cancer patients.

    abstract::Lymphocyte cyclic nucleotide content was studied before and after Levamisole administration to cancer patients. Twelve patients with disseminated cancer received 100 mg/m2 on two consecutive days; nine comparable patients with disseminated cancer served as controls. Endogenous cyclic adenosine monophosphate (cAMP) and...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(197910)44:4<1280::aid-cncr282044

    authors: Lewinski UH,Mavligit GM,Thompson WJ,Hersh EM,Ortez RA

    更新日期:1979-10-01 00:00:00

  • Oncocytic neoplasms of salivary glands: a report of fifteen cases including two malignant oncocytomas.

    abstract::Fifteen oncocytic (oxyphilic granular cell) neoplasms of the salivary glands collected from three large university medical centers are presented. The histologic and ultrastructural criteria that characterize oncocytes are presented and electron micrographs of two of our cases are discussed. Included in the series are ...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(197609)38:3<1306::aid-cncr282038

    authors: Gray SR,Cornog JL Jr,Seo IS

    更新日期:1976-09-01 00:00:00

  • Evaluation of dietetic intervention in children with medulloblastoma or supratentorial primitive neuroectodermal tumors.

    abstract:BACKGROUND:Malnutrition is a common complication of cancer treatment; it can affect energy levels and, as a consequence, quality of life. The goal of the current study was to evaluate the effect of dietetic intervention in a cohort of children treated for medulloblastoma and supratentorial primitive neuroectodermal tum...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.11598

    authors: Bakish J,Hargrave D,Tariq N,Laperriere N,Rutka JT,Bouffet E

    更新日期:2003-09-01 00:00:00

  • Effect of chemotherapy on resting energy expenditure in patients with non-Hodgkin's lymphoma. Results of a sequential study.

    abstract::This study compared the resting energy expenditure (REE) modifications observed during successive intensive identical chemotherapy courses in non-Hodgkin's lymphoma patients to assess indirectly the metabolic changes induced by the cytotoxic effect of drugs on the tumor. With this therapeutic regimen, reduction of tum...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19900601)65:11<2455::aid-cncr282

    authors: Delarue J,Lerebours E,Tilly H,Rimbert A,Hochain P,Guedon C,Piguet H,Colin R

    更新日期:1990-06-01 00:00:00

  • Behavioral and psychosocial cancer research. Building on the past, preparing for the future.

    abstract::This report identifies five general conclusions that emerged from the Second Workshop on Methodology in Behavioral and Psychosocial Cancer Research. These conclusions address diverse topics, including a focus on areas other than methodology; an emphasis on the transfer of technology and knowledge to applied settings; ...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19910201)67:3+<865::aid-cncr2820

    authors: Burish TG

    更新日期:1991-02-01 00:00:00

  • Pediatric cancer mortality and survival in the United States, 2001-2016.

    abstract:BACKGROUND:Although pediatric cancer mortality and survival have improved in the United States over the past 40 years, differences exist by age, race/ethnicity, cancer site, and economic status. To assess progress, this study examined recent mortality and survival data for individuals younger than 20 years. METHODS:Ag...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.33080

    authors: Siegel DA,Richardson LC,Henley SJ,Wilson RJ,Dowling NF,Weir HK,Tai EW,Buchanan Lunsford N

    更新日期:2020-10-01 00:00:00

  • Comparison of estrogen receptor determinations by a biochemical ligand-binding assay and immunohistochemical staining with monoclonal antibody ER1D5 in females with lymph node positive breast carcinoma entered on two prospective clinical trials.

    abstract:BACKGROUND:The measurement of estrogen receptors (ER) in breast cancer specimens has traditionally been assessed with a dextran-coated charcoal assay (DCCA). More recently the immunohistochemical staining (IHC) method has gained increasing popularity because of its ability to use fixed tissue, assess needle biopsies, a...

    journal_title:Cancer

    pub_type: 杂志文章,多中心研究

    doi:10.1002/(SICI)1097-0142(19960815)78:4<764::AID-CNC

    authors: Alberts SR,Ingle JN,Roche PR,Cha SS,Wold LE,Farr GH Jr,Krook JE,Wieand HS

    更新日期:1996-08-15 00:00:00

  • The use of a tumor colony assay in predicting chemotherapeutic drug response in murine bladder cancer.

    abstract::A tumor colony assay (TCA) was evaluated for its ability to predict anticancer drug responses in an N-[4-(5-nitro-2-furyl)-2-thiazolyl]-formamide (FANFT)-induced murine bladder tumor (MBT) model. Ten anticancer drugs were evaluated in vivo and in vitro using four MBT cell lines (40 drug responses). Using the optimum c...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19830815)52:4<619::aid-cncr28205

    authors: Niell HB,Soloway MS,Wood CA,McCallum LW,Webster K

    更新日期:1983-08-15 00:00:00

  • Sites of primary malignancies in patients presenting with cerebral metastases. A review of 120 cases.

    abstract::A retrospective study is reported of 120 consecutive cases of patients presenting with brain metastases as the primary sign of their malignancy. Primary site was found in 62 patients (53 while alive and 9 at postmortem examination) and remained unknown in 58. Lung was the most frequent primary site (45% of known sites...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19850815)56:4<880::aid-cncr28205

    authors: Le Chevalier T,Smith FP,Caille P,Constans JP,Rouesse JG

    更新日期:1985-08-15 00:00:00

  • Colon carcinoma in children and adolescents. A review of 30 cases.

    abstract::Carcinoma of the large bowel is rare in persons under the age of 30, and generally presents with advanced stages of disease. From 1964 to 1984, 30 patients presented with nonfamilial large bowel malignancies. Seventeen patients were male, and 13 female (age range, 8-25 years). In 15 patients the primary was in the rig...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19850315)55:6<1322::aid-cncr2820

    authors: Rao BN,Pratt CB,Fleming ID,Dilawari RA,Green AA,Austin BA

    更新日期:1985-03-15 00:00:00

  • Soluble human epidermal growth factor receptor 2 (HER2) levels in patients with HER2-positive breast cancer receiving chemotherapy with or without trastuzumab: results from North Central Cancer Treatment Group adjuvant trial N9831.

    abstract:BACKGROUND:Increased soluble human epidermal growth factor receptor 2 (sHER2) is an indicator of a poor prognosis in HER2-positive metastatic breast cancer. In this study, the authors evaluated levels of sHER2 during treatment and at the time of disease recurrence in the adjuvant North Central Cancer Treatment Group N9...

    journal_title:Cancer

    pub_type: 杂志文章,随机对照试验

    doi:10.1002/cncr.28130

    authors: Moreno-Aspitia A,Hillman DW,Dyar SH,Tenner KS,Gralow J,Kaufman PA,Davidson NE,Lafky JM,Reinholz MM,Lingle WL,Kutteh LA,Carney WP,Dueck AC,Perez EA

    更新日期:2013-08-01 00:00:00

  • Combination hyperthermia and radiation therapy for malignant melanoma.

    abstract::Since 1975, clinical studies have been carried out to determine whether radiation when combined with localized hyperthermia evokes improved tumor control compared to that achieved with radiation alone. Local tumor hyperthermia was achieved using radiofrequency inductive heating at 27.12 MHz. In bulky lesions (greater ...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19820801)50:3<478::aid-cncr28205

    authors: Kim JH,Hahn EW,Ahmed SA

    更新日期:1982-08-01 00:00:00

  • Weight gain with breast cancer adjuvant treatment.

    abstract::Available information suggests that individuals with breast cancer gain weight during adjuvant treatment and that this weight gain may be associated with poor prognosis. Exploration of the factors which affect weight gain may aid in developing weight control interventions for these patients. To determine the factors w...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19910401)67:7<1954::aid-cncr2820

    authors: Levine EG,Raczynski JM,Carpenter JT

    更新日期:1991-04-01 00:00:00

  • Laboratory aids to diagnosis--enzymes.

    abstract::A summary is presented of those organ specific enzyme assays traditionally used in evaluation of the patient with cancer. In addition, the use of certain serum enzymes such as gamma-glutamyl transpeptidase, phosphohexose isomerase or 5'-nucleotidase as aids in following the course of the disease, particularly in patie...

    journal_title:Cancer

    pub_type: 杂志文章,评审

    doi:10.1002/1097-0142(197601)37:1+<542::aid-cncr282037

    authors: Schwartz MK

    更新日期:1976-01-01 00:00:00

  • Marrow neutrophil reserve after adjuvant chemotherapy for carcinoma of the breast.

    abstract::The hematologic factors of 16 female patients with breast carcinoma who had received adjuvant chemotherapy with L-phenylalanine-based programs for two years were compared with those for 13 normal female volunteers of similar age. The findings include significant suppression of the mean hemoglobin level, of leukocyte c...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19820615)49:12<2455::aid-cncr282

    authors: Corder MP,Jochimsen PR

    更新日期:1982-06-15 00:00:00

  • Preoperative chemotherapy treatment of breast cancer--a review.

    abstract::Despite proven benefits of neoadjuvant chemotherapy in patients with locally advanced, invasive breast cancer, no regimen is recommended as the treatment of choice. Neoadjuvant chemotherapy regimens encompass single-agent and combination therapy and sequential treatment. For this report, the author reviewed the litera...

    journal_title:Cancer

    pub_type: 杂志文章,评审

    doi:10.1002/cncr.23083

    authors: Buzdar AU

    更新日期:2007-12-01 00:00:00

  • Inhibitors against factor VIII in patients with cancer. Analysis of 41 patients.

    abstract:BACKGROUND:The spontaneous formation of neutralizing antibodies (inhibitors) to factor VIII (FVIII) in patients with cancer is a well known phenomenon. However, to the authors' knowledge there is lack of information in the literature with respect to the clinical course of these patients and the nature of the associatio...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(20010315)91:6<1067::aid-cncr1101

    authors: Sallah S,Wan JY

    更新日期:2001-03-15 00:00:00

  • Expression of c-myc oncogene product and ras family oncogene products in various human malignant lymphomas defined by immunohistochemical techniques.

    abstract::The authors studied the expression of c-myc and ras family oncogene products in 43 cases of malignant lymphoma (ML) using the immunoperoxidase method. Unfixed frozen sections of lymph nodes from four patients with Hodgkin's disease and 39 with non-Hodgkin's lymphoma, together with normal lymph nodes, were studied by t...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19881115)62:10<2085::aid-cncr282

    authors: Mitani S,Sugawara I,Shiku H,Mori S

    更新日期:1988-11-15 00:00:00

  • Is axillary lymph node dissection necessary in elderly patients with breast carcinoma who have a clinically uninvolved axilla?

    abstract:BACKGROUND:Axillary dissection in elderly patients with early-stage breast carcinoma who do not have palpable axillary lymph nodes is controversial because of the associated morbidity of the surgery, reduced life expectancy of the patients, and efficacy of hormone therapy in preventing recurrences and axillary events. ...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.11173

    authors: Martelli G,Miceli R,De Palo G,Coradini D,Salvadori B,Zucali R,Galante E,Marubini E

    更新日期:2003-03-01 00:00:00