Evaluation of cell proliferation in breast carcinoma. Comparison of Ki-67 immunohistochemical study, DNA flow cytometric analysis, and mitotic count.

abstract：BACKGROUND:Molecular genetic studies of ovarian cancer have been limited by the inaccessible location of the ovary, the advanced stage of tumors available for analysis, and the lack of a well-defined precursor lesion. However, genetic alterations important in ovarian tumorigenesis have been identified recently. METHOD...

journal_title：Cancer

authors： Gallion HH,Pieretti M,DePriest PD,van Nagell JR Jr

更新日期：1995-11-15 00:00:00

abstract：BACKGROUND:Hepatic artery administration of iodine-131-Lipiodol serves as a modality that delivers targeted radiation therapy to hepatocellular carcinoma. Its efficacy has been promising according to trials conducted in the adjuvant setting after hepatic resection. Further investigation of its role in the palliative se...

journal_title：Cancer

authors： Chua TC,Chu F,Butler SP,Quinn RJ,Glenn D,Liauw W,Morris DL

更新日期：2010-09-01 00:00:00

abstract：BACKGROUND:Increased soluble human epidermal growth factor receptor 2 (sHER2) is an indicator of a poor prognosis in HER2-positive metastatic breast cancer. In this study, the authors evaluated levels of sHER2 during treatment and at the time of disease recurrence in the adjuvant North Central Cancer Treatment Group N9...

journal_title：Cancer

authors： Moreno-Aspitia A,Hillman DW,Dyar SH,Tenner KS,Gralow J,Kaufman PA,Davidson NE,Lafky JM,Reinholz MM,Lingle WL,Kutteh LA,Carney WP,Dueck AC,Perez EA

更新日期：2013-08-01 00:00:00

abstract：:The ability to noninvasively discriminate the most common types of renal cell carcinoma (RCC) based on their magnetic resonance imaging (MRI) appearances or their magnetic resonance phenotypes is achievable. Intracellular lipids, a histologic characteristic of the clear cell RCC, can be identified on chemical shift MR...

journal_title：Cancer

authors： Pedrosa I,Alsop DC,Rofsky NM

更新日期：2009-05-15 00:00:00

abstract：:To determine whether the referral of lung cancer patients to university cancer centers was related to nonclinical factors, the medical charts were reviewed for almost all lung cancer patients diagnosed during the period of 1973-1976 in New Hampshire and Vermont. Greater distance from a cancer center, lower functional ...

journal_title：Cancer

authors： Greenberg ER,Dain B,Freeman D,Yates J,Korson R

更新日期：1988-10-15 00:00:00

abstract：:A primitive neuroectodermal tumor of peripheral nerve origin was examined by light and electron microscopy. The lesion arose in association with the S1 nerve root of the lumbosacral plexus in a 22-year-old female. Following a surgical biopsy, the patient received systemic chemotherapy; however, approximately one-and-a...

journal_title：Cancer

authors： Bolen JW,Thorning D

更新日期：1980-12-01 00:00:00

abstract：BACKGROUND:Among the several proposed risk classification schemes for predicting survival in women with breast carcinoma, one of the most commonly used is the Nottingham Prognostic Index (NPI). The goal of the current study was to use a continuous prognostic model (similar to those that have already been demonstrated t...

journal_title：Cancer

authors： Kattan MW,Giri D,Panageas KS,Hummer A,Cranor M,Van Zee KJ,Hudis CA,Norton L,Borgen PI,Tan LK

更新日期：2004-12-01 00:00:00

abstract：:Demonstration of malignant cells in blood specimens collected during transurethral resection of the prostate (TURP) has implicated TURP in the dissemination of prostatic cancer. Of 153 patients who underwent radiation therapy for prostate cancer between January 1977 and June 1990 and were retrospectively analyzed, 93 ...

journal_title：Cancer

authors： Pansadoro V,Sternberg CN,DePaula F,Florio A,Giannarelli D,Arcangeli G

更新日期：1991-11-01 00:00:00

abstract：BACKGROUND:To the authors' knowledge, the empiric identification of agents and interventions to mitigate chemotherapy-induced peripheral neuropathy (CIPN) has resulted in only 1 agent that modestly mitigates it and no agents or interventions that prevent its development. This speaks to the need for a mechanistic unders...

journal_title：Cancer

authors： St Germain DC,O'Mara AM,Robinson JL,Torres AD,Minasian LM

更新日期：2020-10-15 00:00:00

abstract：BACKGROUND:It is unclear whether patients with Stage II colon carcinoma should be offered adjuvant chemotherapy. Therefore, the authors analyzed the risk factors of these patients to identify high-risk subgroups who may benefit from such treatment. METHODS:The data from 305 patients with Stage II colon carcinoma docum...

journal_title：Cancer

authors： Merkel S,Wein A,Günther K,Papadopoulos T,Hohenberger W,Hermanek P

更新日期：2001-09-15 00:00:00

abstract：:Eight hundred sixty-five patients with a microscopically curative resection for carcinoma of the lung were accepted for study, none of whom were excluded from analysis. Adjuvant therapy was randomly assigned about the tenth to 14th postoperative day; 432 patients (treated) were to receive CCNU and hydroxyurea for one ...

journal_title：Cancer

authors： Shields TW,Higgins GA Jr,Humphrey EW,Matthews MJ,Keehn RJ

更新日期：1982-11-01 00:00:00

abstract：BACKGROUND:Squamous cell carcinoma of the esophagus is endemic in parts of South Africa. Previous case-control studies have shown many associations but no clear etiologic pathway has been established. METHODS:A case-control study of dietary and social factors was performed for 130 patient/control pairs matched for age...

journal_title：Cancer

authors： Sammon AM

更新日期：1998-08-01 00:00:00

abstract：:The current results of trials testing combined surgery and chemotherapy in patients with breast cancer is reviewed. Information concerning eight trials utilizing nine single-agent regimens was obtained. The results at this time are conflicting. There appear to be differences among the regimens utilized in the various ...

journal_title：Cancer

authors： Tormey DC

更新日期：1975-09-01 00:00:00

abstract：BACKGROUND:Cisplatin and carboplatin are essential to management of advanced-stage epithelial ovarian carcinoma. No published data exist regarding carboplatin dose intensity importance in ovarian cancer, nor are there data for the effect of age on the ability to deliver dose-intensive carboplatin. METHODS:Retrospectiv...

journal_title：Cancer

authors： Cornelison TL,Reed E

更新日期：1993-01-15 00:00:00

abstract：:Major findings are presented from a workshop on Quality of Life Assessment in Cancer Symptom Management Trials, sponsored by the National Cancer Institute. Data-driven research reports focused on 3 topics, 1) the rationale and utility of health-related quality of life (HRQOL) assessment, 2) conceptual models, and 3) m...

journal_title：Cancer

authors： Buchanan DR,O'Mara AM,Kelaghan JW,Sgambati M,McCaskill-Stevens W,Minasian L

更新日期：2007-10-01 00:00:00

abstract：:Thirty-six patients were evaluated between 1965 and 1983 for glioma of the optic nerves and/or chiasm. Median follow-up was 10.2 years. Pathologic verification was obtained in 32 patients. Tumor initially confined to the optic nerve recurred in one of five patients after complete resection. The actuarial survival for ...

journal_title：Cancer

authors： Flickinger JC,Torres C,Deutsch M

更新日期：1988-02-15 00:00:00

abstract：BACKGROUND:Fine-needle aspiration biopsy (FNA) has been successful in diagnosing epithelial lesions of the breast. Its role in the evaluation of spindle cell and mesenchymal lesions of the breast, which include a variety of benign and malignant conditions, is less clear. This article discusses the cytologic features an...

journal_title：Cancer

authors： Chhieng DC,Cangiarella JF,Waisman J,Fernandez G,Cohen JM

更新日期：1999-12-25 00:00:00

abstract：:Forty-five patients with advanced non-small cell lung cancer (NSCLC), with progressive inoperable tumors were treated. Twenty-three patients were of "limited" stage. Six patients had received previous thoracic radiotherapy. Patients with central nervous system (CNS) metastases, Karnofsky scores of less than 30 or more...

journal_title：Cancer

authors： Thatcher N,Smith DB,Lind MJ,Anderson H,Barclay J,Chopra MP,Fitzgerald MD

更新日期：1988-01-01 00:00:00

abstract：BACKGROUND:Despite the characteristic histopathologic appearance of alveolar soft-part sarcoma (ASPS), its histogenesis remains unclear, and cytogenetic analysis of ASPS is limited to eight cases so far because of the extreme rarity of this disease. METHODS:The authors document a cytogenetic study of a primary case of...

journal_title：Cancer

authors： Joyama S,Ueda T,Shimizu K,Kudawara I,Mano M,Funai H,Takemura K,Yoshikawa H

更新日期：1999-10-01 00:00:00

abstract：:To evaluate the utility of nuclear morphometry as a prognostic indicator in lung cancer, 5-year follow-up information was obtained in 46 cases of surgically resected Stage I non-small cell lung cancer (NSCLC). Nuclear area, perimeter, major diameter, minor diameter, and nuclear shape factor were determined from repres...

journal_title：Cancer

authors： Cagle PT,Langston C,Fraire AE,Roggli VL,Greenberg SD

更新日期：1992-05-15 00:00:00

abstract：BACKGROUND:To the authors' knowledge there are few data that correlate the expression of the epidermal growth factor receptor (EGFR) with the outcome of patients who have breast carcinoma and are treated with anthracycline chemotherapy. METHODS:Pretreatment tumor tissue samples were available from 82 patients who had ...

journal_title：Cancer

authors： Buchholz TA,Tu X,Ang KK,Esteva FJ,Kuerer HM,Pusztai L,Cristofanilli M,Singletary SE,Hortobagyi GN,Sahin AA

更新日期：2005-08-15 00:00:00

abstract：BACKGROUND:Natural killer (NK) cells are a group of effector cells that act nonspecifically against tumor cells. The correlation between intratumoral NK cell infiltration and clinicopathologic features remains unclear. METHODS:The authors selected 146 patients with gastric carcinoma who underwent gastrectomy at Kagosh...

journal_title：Cancer

authors： Ishigami S,Natsugoe S,Tokuda K,Nakajo A,Che X,Iwashige H,Aridome K,Hokita S,Aikou T

更新日期：2000-02-01 00:00:00

abstract：:While using the natural killer (NK) cell-associated HNK-1 antibody in a panel of hematopoietic cell markers, the authors found that metastatic tumor cells in the bone marrow of a patient with disseminated prostatic carcinoma stained strongly with this antibody using an indirect immunofluorescence technique. More than ...

journal_title：Cancer

authors： Rusthoven JJ,Robinson JB,Kolin A,Pinkerton PH

更新日期：1985-07-15 00:00:00

abstract：:Risk factors associated with local recurrences were analyzed from a series of 3445 clinical Stage I melanoma patients. In single-factor analysis, tumor thickness, ulceration, and increasing age were highly significantly predictive of recurrence (p less than 0.00001). After 5 years of follow-up, local recurrence rates ...

journal_title：Cancer

authors： Urist MM,Balch CM,Soong S,Shaw HM,Milton GW,Maddox WA

更新日期：1985-03-15 00:00:00

abstract：:This study examines the interrelationships of depth of penetration, tumor size, and the number of positive nodes in Dukes C colorectal cancer. The results indicated that depth of tumor penetration was related to both tumor size and the number of positive regional lymph nodes. Tumors with positive nodes which failed to...

journal_title：Cancer

authors： Wolmark N,Fisher ER,Wieand HS,Fisher B

更新日期：1984-06-15 00:00:00

abstract：:Parathyroid adenomas are subdivided into chief cell and oxyphil cell variants. However, the parathyroid carcinomas described thus far have been only of the chief cell type. Two cases of oxyphil cell carcinoma of the parathyroid gland are reported, with light and electron microscopic study. The patients presented appar...

journal_title：Cancer

authors： Obara T,Fujimoto Y,Yamaguchi K,Takanashi R,Kino I,Sasaki Y

更新日期：1985-04-01 00:00:00

abstract：BACKGROUND:Mortality from invasive bladder cancer is common, even with high-quality care. Thus, the best opportunities to improve outcomes may precede the diagnosis. Although screening currently is not recommended, better medical care of patients who are at risk (ie, those with hematuria) has the potential to improve o...

journal_title：Cancer

authors： Hollenbeck BK,Dunn RL,Ye Z,Hollingsworth JM,Skolarus TA,Kim SP,Montie JE,Lee CT,Wood DP Jr,Miller DC

更新日期：2010-11-15 00:00:00

abstract：BACKGROUND:Supratentorial gangliogliomas (GGs) are rare tumors of the central nervous system and are commonly associated with chronic seizures. To date, only case reports and small series of patients with short-term follow-up have been available for the assessment of the potential of GGs to recur and progress. METHODS...

journal_title：Cancer

authors： Luyken C,Blümcke I,Fimmers R,Urbach H,Wiestler OD,Schramm J

更新日期：2004-07-01 00:00:00

abstract：BACKGROUND:Gastrointestinal stromal tumors (GISTs) historically were grouped with leiomyosarcomas (LMSs) based on their morphologic similarities; however, recently, GIST was established unequivocally as a distinct type of sarcoma based on its molecular features and response to imatinib treatment. METHODS:To gain furth...

journal_title：Cancer

authors： Ylipää A,Hunt KK,Yang J,Lazar AJ,Torres KE,Lev DC,Nykter M,Pollock RE,Trent J,Zhang W

更新日期：2011-01-15 00:00:00

abstract：BACKGROUND:The prognosis of pediatric patients with nonpilocytic astrocytoma, and in particular those with anaplastic astrocytoma, is somewhat unpredictable. This study used MIB-1 monoclonal antibody, a proliferative marker that can be used in formalin fixed paraffin embedded tissues, to study nonpilocytic pediatric as...

journal_title：Cancer

authors： Ho DM,Wong TT,Hsu CY,Ting LT,Chiang H

更新日期：1998-06-15 00:00:00