Abstract:
:Demonstration of malignant cells in blood specimens collected during transurethral resection of the prostate (TURP) has implicated TURP in the dissemination of prostatic cancer. Of 153 patients who underwent radiation therapy for prostate cancer between January 1977 and June 1990 and were retrospectively analyzed, 93 were evaluable. Fifty-nine patients required TURP before radiation therapy for prostatic obstruction (BPH and/or cancer); the remaining 34 patients underwent radiation therapy after fine-needle aspiration biopsy. No statistically significant difference in failure rate could be detected between these groups, with a failure rate of 47% (28 of 59 patients) at a median follow-up time of 49 months (range, 8 to 146 months) in the TURP group versus a failure rate of 47% (16 of 34 patients) at a median follow-up time of 50 months (range, 3 to 122 months) in the group who underwent biopsy only (Fisher's exact test, P = 0.23). Within the confines of this retrospective study, it appeared that TURP did not enhance the development of metastatic disease.
journal_name
Cancerjournal_title
Cancerauthors
Pansadoro V,Sternberg CN,DePaula F,Florio A,Giannarelli D,Arcangeli Gdoi
10.1002/1097-0142(19911101)68:9<1895::aid-cncr2820subject
Has Abstractpub_date
1991-11-01 00:00:00pages
1895-8issue
9eissn
0008-543Xissn
1097-0142journal_volume
68pub_type
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