Transurethral resection of the prostate and metastatic prostate cancer.

Abstract:

:Demonstration of malignant cells in blood specimens collected during transurethral resection of the prostate (TURP) has implicated TURP in the dissemination of prostatic cancer. Of 153 patients who underwent radiation therapy for prostate cancer between January 1977 and June 1990 and were retrospectively analyzed, 93 were evaluable. Fifty-nine patients required TURP before radiation therapy for prostatic obstruction (BPH and/or cancer); the remaining 34 patients underwent radiation therapy after fine-needle aspiration biopsy. No statistically significant difference in failure rate could be detected between these groups, with a failure rate of 47% (28 of 59 patients) at a median follow-up time of 49 months (range, 8 to 146 months) in the TURP group versus a failure rate of 47% (16 of 34 patients) at a median follow-up time of 50 months (range, 3 to 122 months) in the group who underwent biopsy only (Fisher's exact test, P = 0.23). Within the confines of this retrospective study, it appeared that TURP did not enhance the development of metastatic disease.

journal_name

Cancer

journal_title

Cancer

authors

Pansadoro V,Sternberg CN,DePaula F,Florio A,Giannarelli D,Arcangeli G

doi

10.1002/1097-0142(19911101)68:9<1895::aid-cncr2820

subject

Has Abstract

pub_date

1991-11-01 00:00:00

pages

1895-8

issue

9

eissn

0008-543X

issn

1097-0142

journal_volume

68

pub_type

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