Absence of correlation between nuclear morphometry and survival in stage I non-small cell lung carcinoma.

abstract：BACKGROUND:Despite recent improvements in the treatment of acute lymphoblastic leukemia (ALL), adult patients still have an overall poor outcome. The future of ALL management relies on the introduction of novel targeted therapies. The authors sought to assess if protein kinases (PKs), frequently deregulated in cancer, ...

journal_title：Cancer

authors： Messina M,Chiaretti S,Tavolaro S,Peragine N,Vitale A,Elia L,Sica S,Levis A,Guarini A,Foà R

更新日期：2010-07-15 00:00:00

abstract：:This report identifies five general conclusions that emerged from the Second Workshop on Methodology in Behavioral and Psychosocial Cancer Research. These conclusions address diverse topics, including a focus on areas other than methodology; an emphasis on the transfer of technology and knowledge to applied settings; ...

journal_title：Cancer

authors： Burish TG

更新日期：1991-02-01 00:00:00

abstract：:The medical records of 243 patients admitted over a five-year period with a diagnosis of carcinoma of the cervix were reviewed to determine (1) the frequency of pulmonary metastasis, (2) the relationship between the stage of the primary lesion and the incidence of pulmonary metastasis, and (3) the relationship between...

journal_title：Cancer

authors： Tellis CJ,Beechler CR

更新日期：1982-04-15 00:00:00

abstract：:Karyotypes from seven patients with thyroid lymphoma were studied before treatment. When the cytogenetic results were correlated with the clinical data, it became evident that there are two distinct groups of patients with thyroid lymphoma. In a group of patients with solely numerical abnormalities the disease is asso...

journal_title：Cancer

authors： Taniwaki M,Nishida K,Misawa S,Takino T,Abe T,Aozasa K,Katagiri S,Yonezawa T,Matsuzuka F,Kuma K

更新日期：1989-03-01 00:00:00

abstract：BACKGROUND:Combined transperineal prostate brachytherapy and external beam radiation therapy (EBRT) is widely used for treatment of prostate cancer. Long-term efficacy and toxicity results of a multicenter phase 2 trial assessing combination of EBRT and transperineal prostate brachytherapy boost with androgen deprivati...

journal_title：Cancer

authors： Hurwitz MD,Halabi S,Archer L,McGinnis LS,Kuettel MR,DiBiase SJ,Small EJ

更新日期：2011-12-15 00:00:00

abstract：:The present overview of advanced prostate cancer required the identification of randomized clinical trials studying the question of maximal androgen blockade versus the classic castration therapy. The heterogeneity of the trials concerned the type of castration (surgical or chemical) and the type of antiandrogen (flut...

journal_title：Cancer

authors： Suciu S,Sylvester R,Iversen P,Christensen I,Denis L

更新日期：1993-12-15 00:00:00

abstract：BACKGROUND:Most relapses of Hodgkin's disease (HD) occur within the first 2 years after diagnosis, but they may develop after a longer observation period. The aim of this study was to define the incidence, clinical course, and prognostic factors for late relapse (LR) of Hodgkin's disease. For this purpose, the authors ...

journal_title：Cancer

authors： Garcia-Carbonero R,Paz-Ares L,Arcediano A,Lahuerta J,Bartolome A,Cortes-Funes H

更新日期：1998-08-01 00:00:00

abstract：:This is a statistical analysis of the use of mammography in the symptomatic patient. Eighty-eight percent of women older than 50 years who had a palpable cancer of the breast had a positive mammogram; only 57% of women younger than 51 years of age had a positive mammogram. When the cancer presented as nipple discharge...

journal_title：Cancer

authors： Edeiken S

更新日期：1989-04-01 00:00:00

abstract：:Radiation-induced small bowel injury is a limiting factor to postoperative tumoricidal pelvic doses exceeding 4500 to 5000 cGy. Data from a review of the literature showed the inadequacy of medical measures and the bad reproducibility of radiation therapeutic attempts to decrease small intestine damage. Recent studies...

journal_title：Cancer

authors： Rodier JF,Janser JC,Rodier D,Dauplat J,Kauffmann P,Le Bouedec G,Giraud B,Lorimier G

更新日期：1991-12-15 00:00:00

abstract：BACKGROUND:The degree of response and the duration of survival of patients treated with mitogen-activated protein kinase (MAPK) inhibitors are highly variable. Whether baseline clinicopathologic factors can predict the clinical course with treatment is largely unknown. METHODS:For 142 consecutive immunotherapy- and MA...

journal_title：Cancer

authors： Menzies AM,Wilmott JS,Drummond M,Lo S,Lyle M,Chan MM,Thompson JF,Guminski A,Carlino MS,Scolyer RA,Kefford RF,Long GV

更新日期：2015-11-01 00:00:00

abstract：BACKGROUND:Colorectal carcinoma (CRC) may be the most frequent form of hereditary cancer. Genetic counseling and testing for heritable CRC is a promising approach for reducing the high incidence and mortality rates associated with the disease. Patients with CRC or those with at least one family member with the disease ...

journal_title：Cancer

authors： Kinney AY,DeVellis BM,Skrzynia C,Millikan R

更新日期：2001-01-01 00:00:00

abstract：:Breast cancer is serious public health problem in countries of all resource levels. Although major advances in the detection and treatment of the disease have occurred in higher income settings, similar progress has been slow or scarce in most low- and middle-income countries (LMCs). The poorer outcomes in LMCs may re...

journal_title：Cancer

authors： Harford J,Azavedo E,Fischietto M,Breast Health Global Initiative Healthcare Systems Panel.

更新日期：2008-10-15 00:00:00

abstract：:Immunoblastic sarcoma is a malignancy of transformed lymphocytes with a high association of occurrence in patients with immune disorders. The youngest previously reported case occurred in a 6-year-old child with immunoblastic lymphadenopathy. The authors report the finding of immunoblastic sarcoma of B-cells in a prev...

journal_title：Cancer

authors： Larson T,Katz DA,Mailliard JA

更新日期：1984-11-01 00:00:00

abstract：BACKGROUND:Smoking and alcoholic beverage drinking habits as well as a family history of cancer are well known risk factors for the multifocal occurrence of squamous cell carcinoma of the esophagus and the head and neck region. However, the role of these risk factors in multiple gastric carcinoma remains to be clarifie...

journal_title：Cancer

authors： Morita M,Kuwano H,Baba H,Taketomi A,Kohnoe S,Tomoda H,Araki K,Saeki H,Kitamura K,Sugimachi K

更新日期：1998-10-01 00:00:00

abstract：:The various radiologic methods used in the detection of hepatic lesions in the oncologic patient are discussed. The advantages and disadvantages of each imaging technique as well as a new diagnostic approach are also discussed. With the rapid technological advances made in cross-sectional imaging, the authors believe ...

journal_title：Cancer

authors： Bernardino ME,Lewis E

更新日期：1982-12-01 00:00:00

abstract：BACKGROUND:Although delay to diagnosis after a breast screening abnormality causes anxiety, its effect on prognosis is unknown. METHODS:Using pooled data from five Canadian organized breast cancer screening programs, the authors used unconditional logistic regression to evaluate the effect of delay to diagnosis on pro...

journal_title：Cancer

authors： Olivotto IA,Gomi A,Bancej C,Brisson J,Tonita J,Kan L,Mah Z,Harrison M,Shumak R

更新日期：2002-04-15 00:00:00

abstract：:Balloon-mesh cytologic screening for esophageal cancer done in 255 asymptomatic high-risk United States veterans (age greater than 40 years, ethanol abuse for greater than 20 years, and cigarette smoking greater than 20 pack years) identified 37 patients with squamous cell dysplasia. Of the 37 patients with dysplasia,...

journal_title：Cancer

authors： Jacob P,Kahrilas PJ,Desai T,Hidvegi D,Walloch J,Yokoo H,Gurley AM,Ostrow JD

更新日期：1990-06-15 00:00:00

abstract：:Light microscopic, immunocytochemical and ultrastructural studies were performed on chondrosarcomas which contained a second, noncartilagenous mesenchymal component. Attention was focused on the nonchondroid portion of each tumor in an attempt to elucidate the histogenesis of this mixed variant of chondrosarcoma. The ...

journal_title：Cancer

authors： Têtu B,Ordóñez NG,Ayala AG,Mackay B

更新日期：1986-07-15 00:00:00

abstract：BACKGROUND:In a previous phase 2 trial, axitinib was active and well tolerated in patients with advanced thyroid cancer. In this second phase 2 trial, the efficacy and safety of axitinib were evaluated further in this population, and pharmacokinetic/pharmacodynamic relationships and patient-reported outcomes were asses...

journal_title：Cancer

authors： Locati LD,Licitra L,Agate L,Ou SH,Boucher A,Jarzab B,Qin S,Kane MA,Wirth LJ,Chen C,Kim S,Ingrosso A,Pithavala YK,Bycott P,Cohen EE

更新日期：2014-09-01 00:00:00

abstract：BACKGROUND:Aberrant methylation is a known cause of cancer initiation and/or progression. There are scant data on the genome-wide methylation pattern of nonfunctioning pancreatic neuroendocrine tumors (NFPanNETs) and sporadic and hereditary NFPanNETs. METHODS:Thirty-three tissue samples were analyzed: they included sa...

journal_title：Cancer

authors： Tirosh A,Mukherjee S,Lack J,Gara SK,Wang S,Quezado MM,Keutgen XM,Wu X,Cam M,Kumar S,Patel D,Nilubol N,Tyagi MV,Kebebew E

更新日期：2019-04-15 00:00:00

abstract：BACKGROUND:Assessment of the responses of osteosarcoma patients to preoperative chemotherapy is of clinical importance. The purpose of this study was to estimate the accuracy of angiography and thallium-201 scintigraphy, compared with histology, in assessing the responses of patients with osteosarcoma to preoperative c...

journal_title：Cancer

authors： Kunisada T,Ozaki T,Kawai A,Sugihara S,Taguchi K,Inoue H

更新日期：1999-09-15 00:00:00

abstract：:Although training programs exist in both medical oncology and geriatrics (approved by the American Board of Internal Medicine), neither is adequate to ensure an appropriate supply of physicians to assume a leadership role in the treatment of the increasing number of geriatric patients who have or will develop a malign...

journal_title：Cancer

authors： Bennett JM,Sahasrabudhe DM,Hall WJ

更新日期：1997-10-01 00:00:00

abstract：BACKGROUND:The combination of paclitaxel with cisplatin or carboplatin has become the preferred chemotherapy regimen in the treatment of epithelial ovarian carcinoma. Anthracyclines also have activity in this disease. We conducted a Phase II study by using the combination of paclitaxel, cisplatin, and epirubicin for th...

journal_title：Cancer

authors： Papadimitriou CA,Moulopoulos LA,Vlahos G,Voulgaris Z,Kiosses E,Georgoulias N,Gika D,Diakomanolis E,Michalas S,Dimopoulos MA

更新日期：2000-10-01 00:00:00

abstract：BACKGROUND:Alpha-interferon and dexamethasone are each effective in patients with multiple myeloma and have a combined inhibitory effect on the in vitro growth of myeloma colonies. The effect of combined therapy in newly diagnosed patients is unknown. METHODS:Fifty-one consecutive patients with previously untreated mu...

journal_title：Cancer

authors： Dimopoulos MA,Weber D,Delasalle KB,Alexanian R

更新日期：1993-11-01 00:00:00

abstract：BACKGROUND:Nonsmall cell lung carcinomas (NSCLCs) are associated with very dismal prognoses, and adjuvant chemotherapy, including irinotecan, taxanes, platin, and vinca alkaloid derivatives, offer patients only slight clinical benefits. Part of the chemoresistance of NSCLC results from the expression in NSCLC cells of ...

journal_title：Cancer

authors： Mathieu A,Remmelink M,D'Haene N,Penant S,Gaussin JF,Van Ginckel R,Darro F,Kiss R,Salmon I

更新日期：2004-10-15 00:00:00

abstract：BACKGROUND:The demonstration of the monoclonality of immunoglobulin heavy chain (IgH) gene rearrangement is an indispensable method for the diagnosis of B-cell lymphoma as well as histocytochemical analysis. For the detection of IgH gene rearrangement, the extraction of DNA from a homogenous cell population is necessar...

journal_title：Cancer

authors： Orba Y,Tanaka S,Nishihara H,Kawamura N,Itoh T,Shimizu M,Sawa H,Nagashima K

更新日期：2003-08-25 00:00:00

abstract：BACKGROUND:The appearance of p53 mutations in colorectal carcinoma was determined, independent of differentiation and tumor stage of the primary tumors, in relation to the survival of patients who were scheduled to undergo liver resection. METHODS:Tumor material was analyzed for p53 mutations in primary colorectal tum...

journal_title：Cancer

authors： Yang Y,Forslund A,Remotti H,Lönnroth C,Andersson M,Brevinge H,Svanberg E,Lindnér P,Hafström L,Naredi P,Lundholm K

更新日期：2001-02-15 00:00:00

abstract：LAY SUMMARY:During the coronavirus disease 2019 (COVID-19) pandemic, cancer screening decreased precipitously; home screening for colorectal cancer diminished less than that for colonoscopy and breast and cervical cancer screening. The authors have highlighted approaches for home cancer screening in addition to telemed...

journal_title：Cancer

authors： Gorin SNS,Jimbo M,Heizelman R,Harmes KM,Harper DM

更新日期：2021-02-15 00:00:00

abstract：:A large lipoma and a large angiomyolipoma of the liver, one case each, are described. In the first case, a 24 X 14-cm homogeneous mass demonstrated a fatty density (-96H) on computed tomography (CT), echogenicity on sonography, and fine neovascular vessels on angiography in the right lobe of the liver. Histopathologic...

journal_title：Cancer

authors： Takayasu K,Shima Y,Muramatsu Y,Moriyama N,Yamada T,Makuuchi M,Hirohashi S

更新日期：1987-03-01 00:00:00

abstract：:Breast fluid was collected from 244 nonlactating Finnish women with no known breast disease and analyzed with respect to various epidemiologic and hormonal parameters commonly associated with breast cancer risk. The data obtained permit characterization of women with breast secretory ability and provide fundamental in...

journal_title：Cancer

authors： Wynder EL,Hill P,Laakso K,Littner R,Kettunen K

更新日期：1981-03-15 00:00:00