Behavioral and psychosocial cancer research. Building on the past, preparing for the future.

abstract：BACKGROUND:The goal of this study was to examine the clinical significance of ZNF217 amplification and assess whether ZNF217 could be a potential therapeutic target in ovarian clear cell carcinoma (OCCC). METHODS:ZNF217 expression and amplification in OCCC was assessed by immunohistochemistry, fluorescence in situ hyb...

journal_title：Cancer

authors： Rahman MT,Nakayama K,Rahman M,Nakayama N,Ishikawa M,Katagiri A,Iida K,Nakayama S,Otsuki Y,Shih IeM,Miyazaki K

更新日期：2012-06-01 00:00:00

abstract：BACKGROUND:Benign and malignant pancreatic mucinous tumors differ in proliferative activity, production of tumor markers, and expression of growth factors. DNA ploidy is a useful index of aggressiveness and poor survival in ductal adenocarcinoma, but has not been studied in pancreatic cystic tumors. METHODS:The DNA pl...

journal_title：Cancer

authors： Southern JF,Warshaw AL,Lewandrowski KB

更新日期：1996-01-01 00:00:00

abstract：BACKGROUND:A positive influence of anticoagulant treatment in small cell lung cancer (SCLC) has been suggested by experimental and clinical data. METHODS:In a multicenter clinical trial, 277 patients with SCLC were randomized either to receive or not to receive subcutaneous heparin injections for 5 weeks at effective ...

journal_title：Cancer

authors： Lebeau B,Chastang C,Brechot JM,Capron F,Dautzenberg B,Delaisements C,Mornet M,Brun J,Hurdebourcq JP,Lemarie E

更新日期：1994-07-01 00:00:00

abstract：:Seven adults had a distinct clinicopathologic type of lymphoproliferative disorder of the bone marrow. All patients presented with weakness and pancytopenia; no evidence of gross extramedullary involvement was found. In 5 cases severe and prolonged bone marrow hypoplasia was associated with combination chemotherapy; 1...

journal_title：Cancer

authors： Barton JC,Conrad ME,Vogler LB,Parmley RT

更新日期：1980-10-15 00:00:00

abstract：:Congenital self-healing histiocytosis (CSHH) is a rare primary histiocytic skin disorder. Only a few cases have been studied by ultrastructure and immunohistochemistry. Here we report a new case that was investigated using an electron microscope and a panel of monoclonal (MCA) and polyclonal (PCA) antibodies. CSHH cel...

journal_title：Cancer

authors： Kanitakis J,Zambruno G,Schmitt D,Cambazard F,Jacquemier D,Thivolet J

更新日期：1988-02-01 00:00:00

abstract：BACKGROUND:Tamoxifen and aminoglutethimide are two hormone therapies reported to be effective palliative approaches for patients with metastatic breast cancer. The current trial was designed to evaluate their relative therapeutic effectiveness. METHODS:Two hundred forty-nine postmenopausal women with advanced breast c...

journal_title：Cancer

authors： Gale KE,Andersen JW,Tormey DC,Mansour EG,Davis TE,Horton J,Wolter JM,Smith TJ,Cummings FJ

更新日期：1994-01-15 00:00:00

abstract：:The kinetic perturbations induced by vincristine, cyclophosphamide, and adriamycin were studied in the bone marrow of a patient with neuroblastoma. Serial marrow samples were studied by dual parameter (Coulter volume and DNA content), flow cytometry, and radioautography, and findings were correlated with cytomorpholog...

journal_title：Cancer

authors： Shackney SE,Bunn PA,Ford SS,Erickson B,Ross WE,Levine AS

更新日期：1980-03-01 00:00:00

abstract：BACKGROUND:Cytogenetics and multicolor flow cytometry (MFC) are useful tools for monitoring outcome of treatment in acute myeloid leukemia (AML). However, no data are available regarding the meaning of results when the 2 tests do not agree. METHODS:The authors of this report analyzed 1464 pairs of concurrent cytogenet...

journal_title：Cancer

authors： Fang M,Storer B,Wood B,Gyurkocza B,Sandmaier BM,Appelbaum FR

更新日期：2012-05-01 00:00:00

abstract：:This study delineates the temporal relationship between immune complex formation and tumor growth, and provides one possible explanation for host immunosuppression during tumor growth. The authors have studied serial circulating immune complex (CIC) levels and interleukin (IL) elaboration by peripheral blood cells (IL...

journal_title：Cancer

authors： Ravikumar T,Steele G Jr,Rodrick M,Ross D,Wilson R,Lahey S,Wright D,Munroe A,King V

更新日期：1984-03-15 00:00:00

abstract：BACKGROUND:A rare occurrence, about 1500 men in the United States develop breast carcinoma each year. Little is known about survival patterns at the population level, particularly about racial/ethnic variation. METHODS:Using data from the Surveillance, Epidemiology, and End Results Program, we examined survival rates ...

journal_title：Cancer

authors： O'Malley CD,Prehn AW,Shema SJ,Glaser SL

更新日期：2002-06-01 00:00:00

abstract：BACKGROUND:The efficacy of postoperative radiotherapy (PORT) for thymic epithelial tumors is still controversial. Using the Japanese Association for Research on the Thymus (JART) database, this study was aimed at clarifying the efficacy of PORT for Masaoka stage II and III thymic carcinoma and thymoma. METHODS:The JAR...

journal_title：Cancer

authors： Omasa M,Date H,Sozu T,Sato T,Nagai K,Yokoi K,Okamoto T,Ikeda N,Tanaka F,Maniwa Y,Japanese Association for Research on the Thymus.

更新日期：2015-04-01 00:00:00

abstract：:A Phase I/II accelerated fractionation study for high-grade cerebral astrocytomas began in October 1987. Forty-two patients, 25 men and 17 women, were entered in the study. Median age was 58.5 years of age (range, 32 to 78 years). Performance status was 0, 1, 2, and 3 on Eastern Cooperative Oncology Group (ECOG) scale...

journal_title：Cancer

authors： Shenouda G,Souhami L,Freeman CR,Hazel J,Lehnert S,Joseph L

更新日期：1991-05-01 00:00:00

abstract：:The natural history of the development of neoplasia in experimental systems may be separated into at least three different stages, those of initiation, promotion and progression. Evidence for such distinct stages has been demonstrated in at least half a dozen different experimental systems. The stage of promotion is t...

journal_title：Cancer

authors： Pitot HC

更新日期：1982-03-15 00:00:00

abstract：:Distant nontraumatic clostridial myonecrosis in association with malignancy is an uncommon disorder, with only 14 well-documented cases previously reported in the English literature. Clostridium perfringens and C. septicum are the most common organisms, usually gaining access to the circulation through an ulcerated le...

journal_title：Cancer

authors： Kaiser CW,Milgrom ML,Lynch JA

更新日期：1986-02-15 00:00:00

abstract：:The authors retrospectively reviewed the clinicopathologic and immunologic features of 65 consecutive cases of childhood lymphoma reported between 1980 and 1989. Southern blot hybridization was also performed in 23 cases to study their association with Epstein-Barr virus (EBV) and human T-cell leukemia virus type 1 (H...

journal_title：Cancer

authors： Lee SH,Su IJ,Chen RL,Lin KS,Lin DT,Chuu WM,Lin KS

更新日期：1991-11-01 00:00:00

abstract：BACKGROUND:There is limited understanding of the association between barriers to care and clinical outcomes within patient navigation programs. METHODS:Secondary analyses of data from the intervention arms of the Patient Navigation Research Program were performed, which included navigated participants with abnormal br...

journal_title：Cancer

authors： Ramachandran A,Snyder FR,Katz ML,Darnell JS,Dudley DJ,Patierno SR,Sanders MR,Valverde PA,Simon MA,Warren-Mears V,Battaglia TA,Patient Navigation Research Program Investigators.

更新日期：2015-11-15 00:00:00

abstract：BACKGROUND:To optimize fotemustine chemotherapy, the authors considered how to combine independent Phase II trials to predict the risk of first occurrence of severe toxicity as a function of initial patient characteristics. METHODS:Clinical data from six Phase II trials were collected. Of the 478 patients enrolled 442...

journal_title：Cancer

authors： Raymond E,Haon C,Boaziz C,Coste M

更新日期：1996-11-01 00:00:00

abstract：:Sixty-two patients with breast cancer treated with Adriamycin-containing adjuvant chemotherapy developed recurrent disease. Four patients refused to take any form of systemic therapy at the time of relapse. Fifty-eight patients were managed with various treatment modalities, and of these 33 (57%) achieved on objective...

journal_title：Cancer

authors： Buzdar AU,Legha SS,Hortobagyi GN,Yap HY,Wiseman CL,Distefano A,Schell FC,Barnes BC,Campos LT,Blumenschein GR

更新日期：1981-06-15 00:00:00

abstract：BACKGROUND:The objective of this study was to discover molecular biomarkers associated with the recurrence of esophageal squamous cell carcinoma (ESCC). METHODS:The authors retrospectively analyzed the hypermethylation status of 11 genes using methylation-specific polymerase chain reaction (PCR) and the expression of ...

journal_title：Cancer

authors： Lee E,Lee BB,Ko E,Kim Y,Han J,Shim YM,Park J,Kim DH

更新日期：2013-05-01 00:00:00

abstract：BACKGROUND:The use of adjuvant tamoxifen to treat postmenopausal breast carcinoma patients as an adjunct to primary surgery is well established. The current study reports the long term results for a low risk stratum in a randomized trial of adjuvant tamoxifen. The main focus of this analysis was to determine whether ta...

journal_title：Cancer

authors： Dalberg K,Johansson H,Johansson U,Rutqvist LE

更新日期：1998-06-01 00:00:00

abstract：:The aims of this study were as follows: to confirm that the presence of estrogen (ER) and progesterone (PgR) receptors is an indicator of clinical behavior of human breast cancer independent of other known prognostic factors; to seek clinical correlates of those receptor values that best predict the overall disease ev...

journal_title：Cancer

authors： Vollenweider-Zerargui L,Barrelet L,Wong Y,Lemarchand-Béraud T,Gómez F

更新日期：1986-03-15 00:00:00

abstract：BACKGROUND:Systemic, high-dose interferon-alpha treatment given three times per week subcutaneously induces tumor regression in approximately 30% of patients with inoperable hepatocellular carcinoma (HCC). The objective of the current study was to determine the efficacy and safety of transcatheter arterial interferon e...

journal_title：Cancer

authors： Yuen MF,Ooi CG,Hui CK,Wong WM,Wong BC,Chan AO,Lai CL

更新日期：2003-06-01 00:00:00

abstract：BACKGROUND:Failure to obtain the requisite follow-up of patients with abnormal mammograms may delay cancer diagnosis and impact outcome. Up to 20% of women do not receive timely recommended follow-up. The current study tested the accuracy of the linkage of payer claims and clinical data to identify the appropriate trea...

journal_title：Cancer

authors： Eberl MM,Watroba N,Reinhardt M,Pomerantz J,Serghany J,Broffman G,Fox CH,Mahoney MC,Edge SB

更新日期：2007-08-01 00:00:00

abstract：:This article reviews the clinicopathologic features and the biological behavior of 24 cases of synovial sarcoma that took origin from the cervical prevertebral connective tissue space and manifested as a retropharyngeal tumor or as a palpable mass in the anterior or posterior cervical triangle. The age of the 24 patie...

journal_title：Cancer

authors： Roth JA,Enzinger FM,Tannenbaum M

更新日期：1975-04-01 00:00:00

abstract：:To investigate the utility of thallium 201 (Tl-201) thyroid scintigraphy for the detection of thyroid malignancies, early and delayed Tl-201 scintigraphy was done in 70 consecutive patients with a clinically solitary cold (Iodine 123 [I-123]) nodule. Early Tl-201 scintigraphy had a sensitivity of 100% and a specificit...

journal_title：Cancer

authors： Bleichrodt RP,Vermey A,Piers DA,de Langen ZJ

更新日期：1987-12-01 00:00:00

abstract：BACKGROUND:Ideally, screening detects cancer at a more curable stage and, as a result, decreases the rate of subsequent diagnosis at a late stage. Although it is suggested that some cancer screening tests have led to substantial increases in early-stage incidence with only marginal reductions in late-stage incidence (e...

journal_title：Cancer

authors： Yang DX,Gross CP,Soulos PR,Yu JB

更新日期：2014-09-15 00:00:00

abstract：:Results of cytogenetic studies of a patient with acute granulocytic leukemia are described. The modal number of chromosomes in cells from bone marrow samples was 43; the karyotype was characterized by missing chromosomes in groups B, C, and E. According to successive studies of the same metaphases by fluorescent stain...

journal_title：Cancer

authors： Sofuni T,Okada H

更新日期：1975-02-01 00:00:00

abstract：:This study describes the inheritance of a defect in pyrimidine catabolism and its association with drug-induced toxicity in a patient receiving 5-fluorouracil (FUra) as adjuvant chemotherapy for breast carcinoma. The study population included the affected patient (proband), nine of her blood relatives, and seven healt...

journal_title：Cancer

authors： Harris BE,Carpenter JT,Diasio RB

更新日期：1991-08-01 00:00:00

abstract：:The incidence of gastric cancer has declined markedly in Finland during the last 4 decades. To document the changes caused by that in the ratio of the intestinal type (IT) to the diffuse type (DT) of gastric carcinoma we compared the 367 cases diagnosed from southwestern Finland at the Department of Pathology, Turku U...

journal_title：Cancer

authors： Laurén PA,Nevalainen TJ

更新日期：1993-05-15 00:00:00

abstract：:Spleen from nine patients with hairy-cell leukemia (HCL) were studied for ultrastructural alterations. In all cases, hairy cells with typical ultrastructural characteristics were observed within splenic cords and sinuses. Hairy cells had numerous cytoplasmic processes that interdigitated with cytoplasmic processes of ...

journal_title：Cancer

authors： Pilon VA,Davey FR,Gordon GB,Jones DB

更新日期：1982-04-15 00:00:00