Abstract:
BACKGROUND:A rare occurrence, about 1500 men in the United States develop breast carcinoma each year. Little is known about survival patterns at the population level, particularly about racial/ethnic variation. METHODS:Using data from the Surveillance, Epidemiology, and End Results Program, we examined survival rates in 1979 men diagnosed with primary invasive breast carcinoma between 1973 and 1997. Race was defined as non-Hispanic white, non-Hispanic black, and other race/ethnicity (predominantly Asian/Pacific Islander and Hispanic). The two outcomes were all-cause and breast carcinoma- specific mortality. Survival curves were drawn using Kaplan-Meier estimates and Cox regression was used to estimate the risk of death with hazard ratios and 95% confidence intervals. For both outcomes, the racial/ethnic survival curves differed significantly when the log rank test was used. Therefore, separate models were run for each racial/ethnic group. Covariates included age, stage, histology, surgery, radiation therapy, and year of diagnosis. Estrogen and progesterone receptor status were available for 616 men. RESULTS:Survival rates differed significantly by race/ethnicity. Overall, 5-year survival rates were 66% for whites, 57% for blacks, and 75% for men of other race/ethnicity. Blacks presented with more advanced disease. By stage, whites and blacks had worse survival rates compared with men of other race/ethnicity. The effects of prognostic factors such as age, surgery type, and radiation were similar, but not always significant, for all groups. Diagnosis year and estrogen receptor status did not affect survival. CONCLUSIONS:Survival following male breast carcinoma differed by race/ethnicity, whereas the prognostic factors associated with survival were similar.
journal_name
Cancerjournal_title
Cancerauthors
O'Malley CD,Prehn AW,Shema SJ,Glaser SLdoi
10.1002/cncr.10521subject
Has Abstractpub_date
2002-06-01 00:00:00pages
2836-43issue
11eissn
0008-543Xissn
1097-0142journal_volume
94pub_type
杂志文章相关文献
CANCER文献大全abstract:BACKGROUND:The authors conducted this study to update their experience with patients who have ovarian serous borderline tumors with noninvasive peritoneal implants, with the objectives of gaining additional insight into the biologic behavior of these tumors and understanding better the effects of postoperative treatmen...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/(sici)1097-0142(19981115)83:10<2157::aid-c
更新日期:1998-11-15 00:00:00
abstract:BACKGROUND:To evaluate the immunologic activity of regional lymph nodes, the phenotype of lymphocytes and the functional expression of cell adhesion molecules (CAMs) on lymph node lymphocytes (LNL-: uninvolved, LNL+: involved) were investigated in patients with gastrointestinal carcinoma. METHODS:The lymphocyte subpop...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/(sici)1097-0142(19961015)78:8<1677::aid-cn
更新日期:1996-10-15 00:00:00
abstract:BACKGROUND:Lymphocyte-predominant Hodgkin lymphoma (LPHL) is a rare, CD20-positive, good prognostic lymphoma in children. Patients with early-stage LPHL who underwent successful surgical lymph node resection alone have been reported. To clarify the optimum treatment strategy in children, European study groups were aske...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.22762
更新日期:2007-07-01 00:00:00
abstract::The ultrastructure of a human pineoblastoma is described. Tumor cells formed nests, palisading row and rosettes. Cells within nests were undifferentiated. Palisade and rosette forming cells had polarized cytoplasms and showed signs of differentiation and surface membrane specialization which included surface end-bulb-...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(197911)44:5<1692::aid-cncr282044
更新日期:1979-11-01 00:00:00
abstract:BACKGROUND:Previous research has demonstrated that many lung cancer survivors report difficulties with symptom control and experience a poor quality of life (QOL). Although recent studies have suggested a relationship of single nucleotide polymorphisms (SNPs) in several cytokine genes with cancer susceptibility and pro...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.25255
更新日期:2010-09-01 00:00:00
abstract:BACKGROUND:Infection is a significant cause of death in patients with aplastic anemia (AA). However, few recent studies have examined infectious complications in patients with AA. METHODS:The authors retrospectively evaluated the type of infections, associated pathogens, and outcome of infectious episodes (IEs) in pat...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.11478
更新日期:2003-07-01 00:00:00
abstract:BACKGROUND:African Americans are diagnosed more frequently with colorectal carcinoma at a later stage compared with Caucasians. One potential reason for the disparity is a lower rate of screening examinations. METHODS:Using Outpatient and Physician-Supplier claims for all Medicare beneficiaries age > or = 65 years in ...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.20014
更新日期:2004-01-15 00:00:00
abstract:BACKGROUND:Previous studies have suggested that the prognosis in patients with extremity soft-tissue sarcomas (ESTS) with isolated lymph node (LN) metastases (stage IV) is comparable to that of patients with high-risk ESTS without metastases (stage III). This study was performed to determine the outcomes of patients wh...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.23363
更新日期:2008-04-15 00:00:00
abstract:BACKGROUND:Endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) biopsy allows the detailed imaging and FNA not only of both intramural and extramural structures and lesions of the gastrointestinal (GI) tract but also of various intraabdominal organs. Thus, EUS-FNA biopsy offers a novel opportunity to evaluate ...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.20498
更新日期:2004-10-25 00:00:00
abstract:BACKGROUND:Several investigators have reported the ability to establish xenografts in nude mice from children with neuroblastomas, but a correlation of prognosis with this establishment and the growth patterns of the neuroblastomas has not been reported. METHODS:Tumor specimens from 58 children with neuroblastomas wer...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19931201)72:11<3331::aid-cncr282
更新日期:1993-12-01 00:00:00
abstract::For women who are candidates for menopausal hormone therapy (MHT), estrogen can provide relief from symptomatic menopause, decrease rates of chronic illnesses, and improve health-related quality of life. However, confusion surrounds the evidence regarding the impact of exogenous estrogen and progesterone on the breast...
journal_title:Cancer
pub_type: 杂志文章,评审
doi:10.1002/cncr.31911
更新日期:2019-02-15 00:00:00
abstract::There is justifiable excitement about the recent introduction of prophylactic vaccines against human papillomavirus (HPV) types 16 (HPV-16) and HPV-18. Preventing these infections theoretically could avert approximately 70% of cervical cancer cases worldwide. In the U.S., numerous influential advocates are calling for...
journal_title:Cancer
pub_type: 杂志文章,评审
doi:10.1002/cncr.22751
更新日期:2007-06-25 00:00:00
abstract:BACKGROUND:Poor prognosis of Stage IV breast cancer patients have at best a 10% 3-year survival rate with conventional chemotherapy. Dose-intensive chemotherapy improved survival rates for some of these patients. METHODS:All patients were Stage IV estrogen receptor-negative or estrogen receptor-positive hormonal refra...
journal_title:Cancer
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1002/1097-0142(19940415)73:8<2157::aid-cncr2820
更新日期:1994-04-15 00:00:00
abstract::A clinicopathologic study of 79 patients with parosteal osteogenic sarcoma revealed that more females than males were affected and that most of the patients were in the second to the fourth decades of life. Sixty-eight percent of the patients had involvement of the posterior aspect of the lower femoral shaft. The roen...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(197605)37:5<2466::aid-cncr282037
更新日期:1976-05-01 00:00:00
abstract:BACKGROUND:The purpose of this study was to examine local definitive therapy for nonmetastatic breast cancer with the Patterns of Care Breast and Prostate Cancer (POCBP) study of the National Program of Cancer Registries (Centers for Disease Control and Prevention). METHODS:POCBP medical record data were re-abstracted...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.29092
更新日期:2015-03-01 00:00:00
abstract:BACKGROUND:Recent advances in the early detection of prostatic adenocarcinoma have stimulated interest in the development of techniques for determining metastatic potential. METHODS:One hundred cases of adenocarcinoma, including 66 biopsy and radical prostatectomy specimens; 20 biopsies alone; and 14 transurethral res...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19931115)72:10<3020::aid-cncr282
更新日期:1993-11-15 00:00:00
abstract:BACKGROUND:The authors recently reported on the role of cyclin E in differentiating ovarian/primary peritoneal carcinoma from malignant peritoneal mesothelioma using gene expression arrays. In the current study, they analyzed the expression of low-molecular weight (LMW) forms of cyclin E in ovarian carcinoma, malignant...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.22918
更新日期:2007-09-15 00:00:00
abstract::Spindle cell lipoma is a specific type of lipoma that is easily mistaken for a liposarcoma. An analysis of 114 cases of this tumor from the files of the Armed Forces Institute of Pathology reveals that is occurs chiefly in male patients between 45 and 70 years of age and affects the regions of the shoulder and posteri...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(197511)36:5<1852::aid-cncr282036
更新日期:1975-11-01 00:00:00
abstract::On the basis of previous findings at this institution, VM-26 and Cytosine Arabinoside (ara-C) were used in combination to treat 33 children with refractory acute lymphocytic leukemia (ALL). Chemotherapy was given by vein twice a week for four weeks at dosage of 300 mg/m2 for ara-C and 50, 75, 110, 165, or 200 mg/m2 fo...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19800315)45:6<1284::aid-cncr2820
更新日期:1980-03-15 00:00:00
abstract:BACKGROUND:The recurrence or mortality rate of axillary lymph node-negative invasive breast cancer has been associated with the tumor S-phase fraction, which is measured by DNA flow cytometry. Because many of the studies that established this association were performed using frozen, pulverized tumor specimens, this ass...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19930915)72:6<1926::aid-cncr2820
更新日期:1993-09-15 00:00:00
abstract:BACKGROUND:Current salvage therapy for recurrent high-risk neuroblastoma is rarely curative. Assessment of the effectiveness of new, primarily cytostatic agents requires the redefinition of study endpoints to reflect disease stabilization rather than tumor response or regression. The intervals of disease control in the...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.23507
更新日期:2008-06-15 00:00:00
abstract::In a clinical trial, 42 patients with abdominal Burkitt's lymphoma (BL) were treated with a combination regimen, code-named CVA, consisting of cyclophosphamide (CTX), vincristine, and cystosine arabinoside. In addition, intrathecal methotrexate (i.t. MTX) was administered as prophylaxis against subsequent central nerv...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(197710)40:4<1410::aid-cncr282040
更新日期:1977-10-01 00:00:00
abstract:BACKGROUND:Recent clinical studies have demonstrated that tumor angiogenesis is a potent prognostic indicator for breast cancer patients. The quantitation of endothelial growth factors is thought to be useful to assess angiogenic phenotype in the tumor. Among the many new endothelial growth factors, vascular endothelia...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/(sici)1097-0142(19960315)77:6<1101::aid-cn
更新日期:1996-03-15 00:00:00
abstract:BACKGROUND:Melanoma vaccine treatment appears to slow the progression of melanoma in some patients, particularly in patients in whom it stimulates cellular antimelanoma immune responses. The relationship of vaccine-induced antibody responses to clinical outcome is less clear. The purpose of this study was to investigat...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19950115)75:2<495::aid-cncr28207
更新日期:1995-01-15 00:00:00
abstract:BACKGROUND:There has been increasing interest in the primary surgical treatment of patients with early T classification (T1-T2) oropharyngeal squamous cell carcinoma (OPSCC), with the stated goal of de-escalating or avoiding adjuvant treatment. Herein, the authors sought to determine the degree to which this interest h...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.29938
更新日期:2016-05-15 00:00:00
abstract::Epithelioid sarcoma is an uncommon tumor characterized by its appearance in the distal extremities (especially the forearm, wrist, and ankle), the tendency to recur locally, and high probability of spread to regional lymph nodes. Most patients have been treated surgically, and the potential role of radiation therapy a...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19830915)52:6<1022::aid-cncr2820
更新日期:1983-09-15 00:00:00
abstract:BACKGROUND:Hemangiopericytomas and malignant solitary fibrous tumors (HPC/SFT) are rare, closely related sarcomas with unpredictable behavior that respond infrequently to chemotherapy. An optimal systemic treatment strategy for advanced HPC/SFT has not yet been identified. METHODS:We retrospectively analyzed the recor...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.26098
更新日期:2011-11-01 00:00:00
abstract:BACKGROUND:The objective of this study was to investigate the potential of virtual microscopy (VM) as an avenue for the delivery of mandatory cytology proficiency tests). METHODS:Three senior cytotechnologists and 2 board-certified cytopathologists participated in 3 virtual proficiency tests. Each set consisted of 10 ...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.22766
更新日期:2007-08-25 00:00:00
abstract::Interleukin-6 (IL-6) plays a major role in the response to injury or infection and is involved in the immune response, inflammation, and hematopoiesis. Its deregulation impacts numerous disease states, including many types of cancer. Consequently, modulating IL-6 may be an innovative therapeutic strategy in several di...
journal_title:Cancer
pub_type: 杂志文章,评审
doi:10.1002/cncr.22999
更新日期:2007-11-01 00:00:00
abstract:BACKGROUND:The authors purpose in this study was to clarify the difference in terms of clinicopathologic features between gastric cancer (GC) with high numbers of DNA methylated genes and CpG island methylator phenotype (CIMP)-positive GC as originally defined. METHODS:We analyzed DNA methylation of 12 tumor-related g...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.21754
更新日期:2006-03-15 00:00:00