Low-molecular weight forms of cyclin E differentiate ovarian carcinoma from cells of mesothelial origin and are associated with poor survival in ovarian carcinoma.

abstract：:Despite proven benefits of neoadjuvant chemotherapy in patients with locally advanced, invasive breast cancer, no regimen is recommended as the treatment of choice. Neoadjuvant chemotherapy regimens encompass single-agent and combination therapy and sequential treatment. For this report, the author reviewed the litera...

journal_title：Cancer

authors： Buzdar AU

更新日期：2007-12-01 00:00:00

abstract：BACKGROUND:The association of Langerhans cell histiocytosis (LCH) with a malignant neoplasm is rare and generally has been the subject of isolated case reports. METHODS:A recent case of LCH seen at the University of Minnesota in combination with acute lymphoblastic leukemia led the authors to review their own charts f...

journal_title：Cancer

authors： Egeler RM,Neglia JP,Puccetti DM,Brennan CA,Nesbit ME

更新日期：1993-02-01 00:00:00

abstract：BACKGROUND:Patients with Stage I Grade 1 endometrial carcinoma have an excellent prognosis and a 10-year survival rate of more than 90%. In every clinical series, however, a few patients in this group have recurrence and die of their disease. METHODS:The authors reviewed 80 patients with Stage I Grade 1 endometrial ca...

journal_title：Cancer

authors： Tornos C,Silva EG,el-Naggar A,Burke TW

更新日期：1992-08-15 00:00:00

abstract：BACKGROUND:In a recently reported, randomized trial, it was found that a regimen of irinotecan once every 3 weeks for patients with advanced colorectal carcinoma was associated with a lower incidence of severe diarrhea compared with weekly treatment, and both regimens had similar efficacy. METHODS:Resource utilization...

journal_title：Cancer

authors： Earle CC,Kwok A,Gazelle GS,Fuchs CS

更新日期：2004-12-01 00:00:00

abstract：BACKGROUND:Preclinical studies have demonstrated that the inhibition of the PI3K/Akt/mTOR pathway restores gefitinib sensitivity in resistant cancer cell lines. A phase 1 study was conducted of the combination of everolimus, an mTOR inhibitor, and gefitinib to determine a daily dose of everolimus with gefitinib in pati...

journal_title：Cancer

authors： Milton DT,Riely GJ,Azzoli CG,Gomez JE,Heelan RT,Kris MG,Krug LM,Pao W,Pizzo B,Rizvi NA,Miller VA

更新日期：2007-08-01 00:00:00

abstract：BACKGROUND:In various neoplasms expression of the proliferation-related Ki-67 antigen has successfully been linked with parameters of progression of disease. While a definite grading scheme for oligodendrogliomas has still not been agreed upon, any parameter of tumor proliferation that might be helpful in predicting cl...

journal_title：Cancer

authors： Kros JM,Hop WC,Godschalk JJ,Krishnadath KK

更新日期：1996-09-01 00:00:00

abstract：BACKGROUND:The sensitivity of the intraoperative diagnosis of sentinel lymph node (SLN) micrometastases and the metastases of invasive lobular carcinoma (ILC) is low. The goal of the current study was to assess whether the use of intraoperative, rapid immunohistochistochemistry (IHC) enhances the intraoperative detecti...

journal_title：Cancer

authors： Leikola JP,Toivonen TS,Krogerus LA,von Smitten KA,Leidenius MH

更新日期：2005-07-01 00:00:00

abstract：:Based on the independent activity of cisplatin, vinblastine, and dimethyl-triazeno-imidazole-carboxamide (DTIC) (CVD), a combination of these agents was used in the treatment of patients with advanced melanoma. Vinblastine was used in a dose of 1.6 mg/m2/d for 5 days, DTIC was used in a dose of 800 mg/m2 intravenously...

journal_title：Cancer

authors： Legha SS,Ring S,Papadopoulos N,Plager C,Chawla S,Benjamin R

更新日期：1989-11-15 00:00:00

abstract：BACKGROUND:It has previously been shown that heparanase-1 (HPR1), an endoglycosidase, is up-regulated in pancreatic carcinoma. The purpose of this study was to test whether serum HPR1 levels in pancreatic carcinoma patients are elevated, and whether higher serum HPR1 levels are associated with a shortened survival. ME...

journal_title：Cancer

authors： Quiros RM,Rao G,Plate J,Harris JE,Brunn GJ,Platt JL,Gattuso P,Prinz RA,Xu X

更新日期：2006-02-01 00:00:00

abstract：BACKGROUND:Early stage lung cancer has a variable prognosis, and there are currently no markers that predict which patients will recur. This study examined the relation between tumor-regulatory T (Treg) cells and total tumor-infiltrating T-cell lymphocytes (TIL) to determine whether they correlated with recurrence. ME...

journal_title：Cancer

authors： Petersen RP,Campa MJ,Sperlazza J,Conlon D,Joshi MB,Harpole DH Jr,Patz EF Jr

更新日期：2006-12-15 00:00:00

abstract：:The case of a 41-year-old man with testicular mixed germ cell-sex cord stroma tumor is reported. The patient noticed a gradual, painless, right-sided testicular enlargement 4 years before being treated by radical orchiectomy. The testis contained a centrally located tumor. There was no evidence of metastases. An histo...

journal_title：Cancer

authors： Matoŝka J,Talerman A

更新日期：1989-11-15 00:00:00

abstract：:A series of eight plasma cell granulomas of the lung were examined. Their clinical, pathologic, and immunohistochemical characteristics as well as the ultrastructural features of one case are in agreement with those found in the literature. One patient died after a surgical intervention complicated by invasion of pulm...

journal_title：Cancer

authors： Warter A,Satge D,Roeslin N

更新日期：1987-02-01 00:00:00

abstract：:The introduction of trimodal combination therapy (surgery + radiation + intraarterial infusion) for maxillary carcinoma resulted in a change in the sites of recurrence and no satisfactory improvement in the local control rate. To examine the cause of these phenomena, external carotid angiography was performed on 51 pa...

journal_title：Cancer

authors： Shibuya H,Suzuki S,Horiuchi J,Takagi M,Okuyama T,Suzuki H,Takeda M

更新日期：1982-12-15 00:00:00

abstract：:Twenty-one patients with bilateral Wilms' tumor are reviewed and the details of diagnosis, therapy, and survival presented. All patients had an abdominal mass at the time of diagnosis. Associated findings included hypertension, aniridia, and genitourinary anomalies. Favorable histologic features were found in all simu...

journal_title：Cancer

authors： Asch MJ,Siegel S,White L,Fonkalsrud E,Hays D,Isaacs H

更新日期：1985-11-15 00:00:00

abstract：BACKGROUND:The current analysis of outcomes in a large series of adult patients with intracranial ependymal tumors contributes to the characterization of the primary prognostic factors and to the therapeutic management of this rare disease, for which limited information is available in the literature. METHODS:The auth...

journal_title：Cancer

authors： Reni M,Brandes AA,Vavassori V,Cavallo G,Casagrande F,Vastola F,Magli A,Franzin A,Basso U,Villa E

更新日期：2004-03-15 00:00:00

abstract：BACKGROUND:Compared with free drug, sterically stabilized liposomal drug has prolonged circulation time and, thereby, higher tumor selectivity and antitumor activity. The stability in plasma is an important consideration in the formulation of clinically useful liposomal drug. A Phase I study of a stable liposomal doxor...

journal_title：Cancer

authors： Hong RL,Tseng YL

更新日期：2001-05-01 00:00:00

abstract：:Lymphoid cells from two patients with hand-mirror variant of acute lymphoblastic leukemia (ALL) were studied with various monoclonal antibodies in attempts to determine their derivation and differentiation. The predominant feature of the malignant bone marrow cells was strong reactivity with antibody 3A1, which stains...

journal_title：Cancer

authors： Gramatzki M,Strong DM,Duval-Arnould B,Morstyn G,Schumacher HR

更新日期：1985-01-01 00:00:00

abstract：:The prognostic importance of various factors was analyzed for 347 patients registered by the Mycosis Fungoides Cooperative Group (MFCG). Extent of skin involvement at the time of registration and number of sites of clinically enlarged lymph nodes were clearly the most important prognostic variables, and were combined ...

journal_title：Cancer

authors： Green SB,Byar DP,Lamberg SI

更新日期：1981-06-01 00:00:00

abstract：:Combined modality therapy consisting of CHOP-Bleo (cyclophosphamide, Adriamycin [doxorubicin], vincristine (Oncovin), prednisone, and bleomycin) and limited-field radiotherapy was given to 47 patients with Stage III and IIIE diffuse large cell lymphomas. Overall 5-year survival and disease-free survival figures are 64...

journal_title：Cancer

authors： Velasquez W,Fuller LM,Oh KK,Hagemeister FB,Sullivan JA,Manning JT,Shullenberger CC

更新日期：1984-04-01 00:00:00

abstract：:A 55-year-old man is reported who initially developed chronic lymphocytic leukemia. Seven years later, after chemotherapy with chlorambucil, chronic myelogenous leukemia was diagnosed in addition to the chronic lymphocytic leukemia. Four previously reported cases with the same sequence of events are reviewed as well a...

journal_title：Cancer

authors： Schreiber ZA,Axelrod MR,Abebe LS

更新日期：1984-08-15 00:00:00

abstract：BACKGROUND:From 1973 to 1991, the incidence of kidney cancer in the United States increased by 35.4%. METHODS:A multicenter, hospital-based case-control study was conducted from 1977 to 1993 through an interview of 788 patients with renal cell carcinoma and 779 control subjects. RESULTS:Compared with those who never ...

journal_title：Cancer

authors： Muscat JE,Hoffmann D,Wynder EL

更新日期：1995-05-15 00:00:00

abstract：BACKGROUND:Socioeconomic status represents an established barrier to health care access. Age, sex, and race may also play a role. The authors examined whether these affect the access to high-volume hospitals for uro-oncologic procedures in the United States. METHODS:Within the Nationwide Inpatient Sample (NIS), the au...

journal_title：Cancer

authors： Trinh QD,Sun M,Sammon J,Bianchi M,Sukumar S,Ghani KR,Jeong W,Dabaja A,Shariat SF,Perrotte P,Agarwal PK,Rogers CG,Peabody JO,Menon M,Karakiewicz PI

更新日期：2012-09-15 00:00:00

abstract：:A case-control study was conducted to assess the risk factors associated with the development of a contralateral primary breast cancer among women who had had a first primary breast cancer. Hospital records were reviewed for 292 women with an incident contralateral breast cancer, diagnosed in one of eight hospitals be...

journal_title：Cancer

authors： Horn PL,Thompson WD

更新日期：1988-07-15 00:00:00

abstract：BACKGROUND:In the United States, neoadjuvant chemoradiotherapy (NACRT) is widely accepted as the standard of care in the treatment of patients with locally advanced rectal cancer. In the current study, the authors attempted to examine patterns of treatment in the United States over the past decade. METHODS:Using the N...

journal_title：Cancer

authors： Sineshaw HM,Jemal A,Thomas CR Jr,Mitin T

更新日期：2016-07-01 00:00:00

abstract：BACKGROUND:This article reviews the salient pathologic and clinical features of 171 patients with Stage III-IV disease who were 60 years of age or older who were treated on four Hodgkin disease (HD) protocols from 1969 to 1988. METHODS:Pretherapy sections were reviewed centrally for correlation of the histologic class...

journal_title：Cancer

authors： Mir R,Anderson J,Strauchen J,Nissen NI,Cooper MR,Rafla S,Canellos GP,Bloomfield CD,Gottlieb AJ,Peterson B

更新日期：1993-03-01 00:00:00

abstract：BACKGROUND:A phase II prospective trial was carried out to study the concept of 5-fluorouracil (5-FU) dose-intensity in patients with advanced colorectal cancer. Forty patients were treated with 5-FU plus leucovorin (LV), with individually increasing doses of 5-FU. A 5-FU pharmacokinetic follow up was performed and a r...

journal_title：Cancer

authors： Gamelin EC,Danquechin-Dorval EM,Dumesnil YF,Maillart PJ,Goudier MJ,Burtin PC,Delva RG,Lortholary AH,Gesta PH,Larra FG

更新日期：1996-02-01 00:00:00

abstract：BACKGROUND:The ability to divide subsets of patients with glial neoplasms into prognostic groups currently is limited because only a few clinical and pathologic variables are available. The goal of this investigation was to identify biologic factors of potential prognostic value in patients with cerebral gliomas. METH...

journal_title：Cancer

authors： Ganju V,Jenkins RB,O'Fallon JR,Scheithauer BW,Ransom DT,Katzmann JA,Kimmel DW

更新日期：1994-08-01 00:00:00

abstract：BACKGROUND:Patients with non-Hodgkin lymphoma (NHL) have an increased risk of venous thromboembolism (VTE), particularly when they are receiving treatment. Blood or marrow transplantation (BMT) is recommended for relapsed/refractory NHL, and the risk of VTE after these patients undergo BMT is uncertain. METHODS:Patien...

journal_title：Cancer

authors： Gangaraju R,Chen Y,Hageman L,Wu J,Francisco L,Kung M,Ness E,Parman M,Weisdorf DJ,Forman SJ,Arora M,Armenian SH,Bhatia S

更新日期：2019-12-15 00:00:00

abstract：BACKGROUND:Ovarian surface epithelial cells are positionally organized as a single cell layer by a sheet of basement membrane. It is believed that the contact of the ovarian surface epithelial cells with the basement membrane regulates cell growth and ensures the organization of the epithelium. Disabled-2 (Dab2), a sig...

journal_title：Cancer

authors： Capo-Chichi CD,Smith ER,Yang DH,Roland IH,Vanderveer L,Cohen C,Hamilton TC,Godwin AK,Xu XX

更新日期：2002-10-15 00:00:00

abstract：:In a series of 25 patients with head and neck cancer who had severe pain, the type and cause of the pain were analyzed. There were two types of pain: nociceptive and non-nociceptive. Nineteen (76%) patients had nociceptive pain that could be subdivided into actual nociceptive pain (9 patients), nociceptive nerve pain ...

journal_title：Cancer

authors： Vecht CJ,Hoff AM,Kansen PJ,de Boer MF,Bosch DA

更新日期：1992-07-01 00:00:00