Two schedules of second-line irinotecan for metastatic colon carcinoma.

abstract：:Seven patients with advanced locoregional or metastatic squamous cell carcinoma of the skin were treated with cis-daimminedichloroplatin (cisplatin) and 5-fluorouracil (5-FU). Responses were seen in six of seven patients (three partial responses [PR] and three complete responses [CR]). One patient is alive and disease...

journal_title：Cancer

authors： Khansur T,Kennedy A

更新日期：1991-04-15 00:00:00

abstract：BACKGROUND:The development of novel therapies for the myelodysplastic syndromes (MDS) is hampered by inadequate trial recruitment. Factors contributing to low trial accrual are incompletely understood. METHODS:This study analyzed a pooled patient database from institutions of the US MDS Clinical Research Consortium to...

journal_title：Cancer

authors： Brierley CK,Zabor EC,Komrokji RS,DeZern AE,Roboz GJ,Brunner AM,Stone RM,Sekeres MA,Steensma DP

更新日期：2020-11-01 00:00:00

abstract：:A case of primary leptomeningeal B-cell lymphoma in an 8-year-old, previously healthy child is described. The child was found to have hypogammaglobulinemia, and the Epstein-Barr virus genome was identified in cultured tumor cells despite blood serology being negative for the virus. The patient was treated with cycloph...

journal_title：Cancer

authors： Hayani A,Venger BH,Rouah E,Laurent JP,Mahoney DH,McClain KL

更新日期：1990-10-15 00:00:00

abstract：BACKGROUND:Patients with invasive breast carcinoma who are ages 35-40 years or younger at the time of diagnosis have been found in several studies to have worse prognosis and higher local failure rates after breast-conserving therapy (BCT) compared with older patients. However, it is uncertain whether specific clinical...

journal_title：Cancer

authors： Zhou P,Recht A

更新日期：2004-09-15 00:00:00

abstract：:The case of a 41-year-old man with testicular mixed germ cell-sex cord stroma tumor is reported. The patient noticed a gradual, painless, right-sided testicular enlargement 4 years before being treated by radical orchiectomy. The testis contained a centrally located tumor. There was no evidence of metastases. An histo...

journal_title：Cancer

authors： Matoŝka J,Talerman A

更新日期：1989-11-15 00:00:00

abstract：:Few epidemiologic studies have been undertaken to investigate the etiology of cancer of the vulva. To identify risk factors associated with this cancer, a case-control study was conducted in 149 patients with histologically proven vulvar carcinoma and the same number of control patients matched for age, race, marital ...

journal_title：Cancer

authors： Mabuchi K,Bross DS,Kessler II

更新日期：1985-04-15 00:00:00

abstract：BACKGROUND:There are few reports comparing the clinicopathologic features of sarcomas of the aorta (SA), sarcomas of the inferior vena cava (SIVC), and sarcomas of the pulmonary artery (SPA). METHODS:The authors retrospectively reviewed 11 SA, 16 SIVC, and 16 SPA, and compared clinical, pathologic, and immunohistochem...

journal_title：Cancer

authors： Burke AP,Virmani R

更新日期：1993-03-01 00:00:00

abstract：:A case of thymoma in a 12-year-old boy is presented. The patient had a history of thymic irradiation in infancy, and a family history of leukemia. The mass was readily resected and the patient is well 10 years later. The tumor contained an unusual admixture of normal thymic tissue with the neoplastic epithelial elemen...

journal_title：Cancer

authors： Chatten J,Katz SM

更新日期：1976-02-01 00:00:00

abstract：BACKGROUND:The delivery of effective treatment for pediatric solid tumors poses a particular challenge to centers in middle-income countries (MICs) that already are vigorously addressing pediatric cancer. The objective of this study was to improve the current understanding of barriers to effective treatment of pediatri...

journal_title：Cancer

authors： Friedrich P,Ortiz R,Fuentes S,Gamboa Y,Ah Chu-Sanchez MS,Arambú IC,Montero M,Báez F,Rodríguez-Galindo C,Antillón-Klussmann F,Central American Association of Pediatric Hematologists and Oncologists (AHOPCA).

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Patients with renal masses are at risk for having or developing chronic kidney disease (CKD) stage 3 (glomerular filtration rate [GFR] <60 mL per minute/1.73 m2). In this study, the authors investigated whether the Screening for Occult Renal Disease (SCORED) model could identify patients with renal masses wh...

journal_title：Cancer

authors： Lucas SM,Nuss G,Stern J,Lotan Y,Sagalowsky AI,Cadeddu JA,Raj GV

更新日期：2008-11-15 00:00:00

abstract：:Extracardiac rhabdomyomas are rare benign neoplasms that in the past have been divided by histologic criteria into adult and fetal types. In this series, 15 previously unpublished cases are presented and analyzed in combination with 51 acceptable cases from the literature. The adult type of rhabdomyoma occurs almost e...

journal_title：Cancer

authors： Di Sant'Agnese PA,Knowles DM 2nd

更新日期：1980-08-15 00:00:00

abstract：BACKGROUND:Endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) biopsy allows the detailed imaging and FNA not only of both intramural and extramural structures and lesions of the gastrointestinal (GI) tract but also of various intraabdominal organs. Thus, EUS-FNA biopsy offers a novel opportunity to evaluate ...

journal_title：Cancer

authors： Jhala NC,Jhala D,Eloubeidi MA,Chhieng DC,Crowe DR,Roberson J,Eltoum I

更新日期：2004-10-25 00:00:00

abstract：:Three hundred fifteen radioisotopic bone scans ranging from initial scan only to nine scans per patient, performed on 114 patients with adenocarcinoma of the prostate between 1979 and 1984, were reviewed. Seventeen patients had positive scans, ten on initial scan and seven at follow-up. Nine patients had bone pain at ...

journal_title：Cancer

authors： Corrie D,Timmons JH,Bauman JM,Thompson IM

更新日期：1988-06-15 00:00:00

abstract：:The DNA content of human plasma cells from myeloma patients relative to that of leukocytes was determined by flow and microscopic cytofluorometry after propidium iodide and fluorescent Feulgen staining, respectively. Mononucleated myeloma plasma cells from all of the 17 patients studied contained more DNA (17 to 58%) ...

journal_title：Cancer

authors： Brox L,Mowles D,Pollock B,Belch A

更新日期：1981-05-15 00:00:00

abstract：:Between September 21, 1973 and May 9, 1975, 36 patients with metastatic cervical adenopathy from cancers primarily arising in the pharynx or oral cavity, including six with bilateral cervical involvement, received fast neutron teletherapy at the University of Washington. At the conclusion of treatment, the masses were...

journal_title：Cancer

authors： Berry HC,Parker RG,Gerdes AJ

更新日期：1976-06-01 00:00:00

abstract：BACKGROUND:Many trials submitted to scientific meetings are not reported in peer-reviewed journals. Results may vary substantially and the lack of final publication constitutes a form of reporting bias. The authors sought to determine the presentation and publication rates of Phase I trials submitted to a major oncolog...

journal_title：Cancer

authors： Camacho LH,Bacik J,Cheung A,Spriggs DR

更新日期：2005-10-01 00:00:00

abstract：:A number of problems inherent to quality of care evaluation have been described above. Although issues such as limited resources and clinical staff resistance may not be specific to cancer care, they certainly impact on the evaluation of the quality of care offered to cancer patients. Other issues such as complexity o...

journal_title：Cancer

authors： Miransky LJ

更新日期：1989-07-01 00:00:00

abstract：:Studies of chemotherapy in advanced or recurrent gynecologic cancer have focussed on ovarian, cervical, and endometrial carcinoma. For celomic epithelial carcinomas of the ovary, a large number of cytotoxic agents have been shown to be active. Dramatic improvement in frequency of response with lesser improvement in su...

journal_title：Cancer

authors： Thigpen T,Vance R,Lambuth B,Balducci L,Khansur T,Blessing J,McGehee R

更新日期：1987-10-15 00:00:00

abstract：BACKGROUND:Based on prior experience with dacarbazine (DTIC) and an outpatient interleukin-2 (IL-2) regimen, the current study was conducted to improve the antitumor efficacy and assess the immunologic interactions between chemotherapy and IL-2. METHODS:Thirty-two patients were registered onto a treatment program, whi...

journal_title：Cancer

authors： Flaherty LE,Robinson W,Redman BG,Gonzalez R,Martino S,Kraut M,Valdivieso M,Rudolph AR

更新日期：1993-06-01 00:00:00

abstract：:This article documents the study of 383 cases of lung cancer in uranium miners and presents for the first time the relationship of radioactive radon gas and cigarette smoking. There is evidence that alpha radiation from radon gas at exposure levels above 465 working level months (WLM) is a strong contributor to the de...

journal_title：Cancer

authors： Saccomanno G,Huth GC,Auerbach O,Kuschner M

更新日期：1988-10-01 00:00:00

abstract：:The ultrastructure of a human pineoblastoma is described. Tumor cells formed nests, palisading row and rosettes. Cells within nests were undifferentiated. Palisade and rosette forming cells had polarized cytoplasms and showed signs of differentiation and surface membrane specialization which included surface end-bulb-...

journal_title：Cancer

authors： Kline KT,Damjanov I,Katz SM,Schmidek H

更新日期：1979-11-01 00:00:00

abstract：BACKGROUND:Expression of oncofetal fibronectin (oncFN) and normal fibronectin (norFN) in colorectal cancer specimens was examined to investigate the correlation between fibronectin localization and histologic grade, liver metastasis, and prognosis. METHODS:Immunohistochemical staining of oncFN and norFN was performed ...

journal_title：Cancer

authors： Inufusa H,Nakamura M,Adachi T,Nakatani Y,Shindo K,Yasutomi M,Matsuura H

更新日期：1995-06-15 00:00:00

abstract：BACKGROUND:The Ets-1 transcription factor has been proposed to play an important role in the invasive process of tumor cells through the induction of urokinase-type plasminogen activator (u-PA). METHODS:Because meningiomas are potentially invasive tumors, irrespective of their malignancy grades, the authors immunohist...

journal_title：Cancer

authors： Kitange G,Tsunoda K,Anda T,Nakamura S,Yasunaga A,Naito S,Shibata S

更新日期：2000-12-01 00:00:00

abstract：:Two human Burkitt's lymphoma cell lines (HBL-4 and HBL-5) were established individually from two patients with small noncleaved cell lymphoma (Burkitt's type). The HBL-4 cell line is Epstein-Barr virus (EBV)-negative, and the HBL-5 cell line is EBV-positive. Cytogenetically, both cell lines had the same chromosomal tr...

journal_title：Cancer

authors： Abe M,Tasaki K,Tominaga K,Fukuhara S,Imai S,Osato T,Wakasa H

更新日期：1992-02-01 00:00:00

abstract：:This study compared the resting energy expenditure (REE) modifications observed during successive intensive identical chemotherapy courses in non-Hodgkin's lymphoma patients to assess indirectly the metabolic changes induced by the cytotoxic effect of drugs on the tumor. With this therapeutic regimen, reduction of tum...

journal_title：Cancer

authors： Delarue J,Lerebours E,Tilly H,Rimbert A,Hochain P,Guedon C,Piguet H,Colin R

更新日期：1990-06-01 00:00:00

abstract：:The close observation of patients treated for testicular cancer led to the suspicion of intrathoracic and/or mediastinal metastases on radiologic examination in a number of patients without other evidence of relapse. This report presents two patients with combined seminomatous and nonseminomatous germ cell tumors with...

journal_title：Cancer

authors： Looijen R,Hoekstra HJ,Sleijfer DT,Postmus P,Oosterhuis JW,de Boer WJ,Schraffordt Koops H

更新日期：1990-11-15 00:00:00

abstract：:111Indium-Bleomycin (111In-Blm), a new radiopharmaceutical, was administered intravenously to 37 patients with benign and malignant breast lesions. Early and delayed images of both the breasts and axillae were made, and results were correlated with physical examination, histopathology of the excised lesion, mammograph...

journal_title：Cancer

authors： Silverstein MJ,Verma RC,Greenfield L,Morton DL

更新日期：1976-01-01 00:00:00

abstract：BACKGROUND:It has been established that comparative genomic hybridization (CGH) on Papanicolaou-stained cervical smears can be used to identify chromosomal imbalances. METHODS:In this study, the authors identified normal and dysplastic squamous epithelial cells cytologically, eliminated surrounding bacteria or leukocy...

journal_title：Cancer

authors： Aubele M,Zitzelsberger H,Schenck U,Walch A,Höfler H,Werner M

更新日期：1998-12-25 00:00:00

abstract：BACKGROUND:Wild-type p53 protein activates the WAF1/CIP-1 (p21) gene, leading to G1 arrest after DNA damage. The authors investigated the relation of p21 and p53 expression in pancreatic adenocarcinomas to disease stage, overall patient survival, and survival when chemotherapy or radiation therapy was given. METHODS:P...

journal_title：Cancer

authors： Dergham ST,Dugan MC,Joshi US,Chen YC,Du W,Smith DW,Arlauskas P,Crissman JD,Vaitkevicius VK,Sarkar FH

更新日期：1997-08-01 00:00:00

abstract：BACKGROUND:Various methods of detecting cancer with fluorescence have been developed. One type of fluorescence is based on the tumor-localizing properties of certain dyes. However, the phototoxicity of most known tumor-localizing dyes hinders the safe use of such diagnostic methods. The authors have developed a fluores...

journal_title：Cancer

authors： Lazarev VV,Roth RA,Kazakevich Y,Hang J

更新日期：1999-04-01 00:00:00