Abstract:
:A case of primary leptomeningeal B-cell lymphoma in an 8-year-old, previously healthy child is described. The child was found to have hypogammaglobulinemia, and the Epstein-Barr virus genome was identified in cultured tumor cells despite blood serology being negative for the virus. The patient was treated with cyclophosphamide, doxorubicin, vincristine, and dexamethasone, plus intrathecal methotrexate, and initially improved. Before the initiation of craniospinal radiation, the patient developed progressive disease, deteriorated, and died 9 months after the onset of symptoms.
journal_name
Cancerjournal_title
Cancerauthors
Hayani A,Venger BH,Rouah E,Laurent JP,Mahoney DH,McClain KLdoi
10.1002/1097-0142(19901015)66:8<1856::aid-cncr2820subject
Has Abstractpub_date
1990-10-15 00:00:00pages
1856-60issue
8eissn
0008-543Xissn
1097-0142journal_volume
66pub_type
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