Primary leptomeningeal B-cell lymphoma in a 8-year-old child.

Abstract:

:A case of primary leptomeningeal B-cell lymphoma in an 8-year-old, previously healthy child is described. The child was found to have hypogammaglobulinemia, and the Epstein-Barr virus genome was identified in cultured tumor cells despite blood serology being negative for the virus. The patient was treated with cyclophosphamide, doxorubicin, vincristine, and dexamethasone, plus intrathecal methotrexate, and initially improved. Before the initiation of craniospinal radiation, the patient developed progressive disease, deteriorated, and died 9 months after the onset of symptoms.

journal_name

Cancer

journal_title

Cancer

authors

Hayani A,Venger BH,Rouah E,Laurent JP,Mahoney DH,McClain KL

doi

10.1002/1097-0142(19901015)66:8<1856::aid-cncr2820

subject

Has Abstract

pub_date

1990-10-15 00:00:00

pages

1856-60

issue

8

eissn

0008-543X

issn

1097-0142

journal_volume

66

pub_type

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