Reticulum cell sarcomas (large cell lymphomas) presenting in the skin. High frequency of true histiocytic lymphoma.

Abstract:

:The clinical and histologic data from 12 patients with "reticulum cell sarcoma" (large cell lymphoma) presenting in the skin were reviewed. Moreover, when appropriate material was available additional immunological, cytochemical and ultrastructural techniques were used to define the nature of the neoplastic cells. Eight tumors were found to be of true histiocytic origin (histiocytic sarcoma), three of B-cell origin (two B-immunoblastic lymphomas and one centroblastic or large noncleaved follicle center cell lymphoma) and one case could not be classified. Possible explanations for the discrepancy between the current report and other studies as to the frequency of true histiocytic tumors will be discussed. The differentiation into T-cell, B-cell and true histiocytic lymphomas appears to be important, not only because of different clinical behaviour, but possibly also from a therapeutical point of view.

journal_name

Cancer

journal_title

Cancer

authors

Willemze R,Ruiter DJ,Van Vloten WA,Meijer CJ

doi

10.1002/1097-0142(19821001)50:7<1367::aid-cncr2820

subject

Has Abstract

pub_date

1982-10-01 00:00:00

pages

1367-79

issue

7

eissn

0008-543X

issn

1097-0142

journal_volume

50

pub_type

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