The practice patterns of adult oncologists' care of pediatric oncology patients.

abstract：BACKGROUND:Despite recent improvements in the treatment of acute lymphoblastic leukemia (ALL), adult patients still have an overall poor outcome. The future of ALL management relies on the introduction of novel targeted therapies. The authors sought to assess if protein kinases (PKs), frequently deregulated in cancer, ...

journal_title：Cancer

authors： Messina M,Chiaretti S,Tavolaro S,Peragine N,Vitale A,Elia L,Sica S,Levis A,Guarini A,Foà R

更新日期：2010-07-15 00:00:00

abstract：BACKGROUND:The aim of this study was to determine and compare the added prognostic value of screening tools, geriatric assessment (GA) components, and GA summaries to clinical information for overall survival (OS) in older patients with cancer. METHODS:A screening and a 10-item GA were systematically performed in pati...

journal_title：Cancer

authors： Kenis C,Baitar A,Decoster L,De Grève J,Lobelle JP,Flamaing J,Milisen K,Wildiers H

更新日期：2018-09-15 00:00:00

abstract：BACKGROUND:Ovarian dysplasia has been defined by histologic and morphometric studies focusing on architectural and nuclear profile changes. A new technique is used to enhance the accuracy of this diagnosis by a quantitative evaluation of the nuclear texture that represents the nuclear chromatin pattern on which convent...

journal_title：Cancer

authors： Deligdisch L,Miranda C,Barba J,Gil J

更新日期：1993-12-01 00:00:00

abstract：BACKGROUND:Despite the widespread use of oxaliplatin-based regimens for colorectal and other gastrointestinal cancers, there is surprisingly little information regarding their empiric use for the treatment of carcinoma of unknown primary site (CUP). In the current study, the combination of oxaliplatin and capecitabine ...

journal_title：Cancer

authors： Hainsworth JD,Spigel DR,Burris HA 3rd,Shipley D,Farley C,Macias-Perez IM,Barton J,Greco FA

更新日期：2010-05-15 00:00:00

abstract：:Surgery is the most effective treatment for thyroid cancer; however, in some subsets of patients, the role of radiotherapy (RT) is important. The main indication for external-beam RT is incomplete surgery. When neoplastic tissue is left behind at operation, RT must be considered, but only if an experienced surgeon fee...

journal_title：Cancer

authors： Tubiana M,Haddad E,Schlumberger M,Hill C,Rougier P,Sarrazin D

更新日期：1985-05-01 00:00:00

abstract：BACKGROUND:A considerable body of evidence supports the concept that a significant number of cutaneous malignant melanomas progress through a precursor lesion or dysplastic melanocytic nevi (DN). Tumor angiogenesis likely plays a critical role in early development of melanoma, and intermediate biomarkers of angiogenesi...

journal_title：Cancer

authors： Einspahr JG,Thomas TL,Saboda K,Nickolof BJ,Warneke J,Curiel-Lewandrowski C,Ranger-Moore J,Duckett L,Bangert J,Fruehauf JP,Alberts DS

更新日期：2007-12-01 00:00:00

abstract：BACKGROUND:The MAGE, BAGE, and GAGE gene families code for distinct, tumor specific antigens that are recognized by cytotoxic T lymphocytes in the context of HLA molecules. The purpose of this study was to analyze MAGE, BAGE, and GAGE gene expression in the two major histologic types of esophageal carcinoma, squamous c...

journal_title：Cancer

authors： Zambon A,Mandruzzato S,Parenti A,Macino B,Dalerba P,Ruol A,Merigliano S,Zaninotto G,Zanovello P

更新日期：2001-05-15 00:00:00

abstract：BACKGROUND:Despite optimal therapy with surgery and radiotherapy, the prognosis of patients with glioblastomas remains poor. Stereotactic brachytherapy involves the accurate placement of radioactive isotopes within brain tumors, significantly increasing the dose of radiation that can be delivered to the tumor bed witho...

journal_title：Cancer

authors： Wen PY,Alexander E 3rd,Black PM,Fine HA,Riese N,Levin JM,Coleman CN,Loeffler JS

更新日期：1994-06-15 00:00:00

abstract：:Ovarian cancer disproportionately affects women 65 years of age and older who are likely to have concomitant changes in physical ability, physiological functioning, and other chronic conditions associated with advancing age. The National Institute on Aging, National Cancer Institute, and the American Cancer Society co...

journal_title：Cancer

authors： Yancik R,Moore TD,Martin G,Obrams GI,Reed E

更新日期：1993-01-15 00:00:00

abstract：:This article documents the study of 383 cases of lung cancer in uranium miners and presents for the first time the relationship of radioactive radon gas and cigarette smoking. There is evidence that alpha radiation from radon gas at exposure levels above 465 working level months (WLM) is a strong contributor to the de...

journal_title：Cancer

authors： Saccomanno G,Huth GC,Auerbach O,Kuschner M

更新日期：1988-10-01 00:00:00

abstract：:The development of monoclonal antibodies has led to renewed interest in the use of antibodies to treat malignant disease. Unfortunately, treatment with unmodified antibodies has been disappointing. Therapy with unmodified antibodies has been limited by the failure of host effector mechanisms to eliminate antibody-coat...

journal_title：Cancer

authors： Badger CC,Bernstein ID

更新日期：1986-07-15 00:00:00

abstract：BACKGROUND:Seminal vesicle (SV) invasion at the time of radical prostatectomy (RP) generally is considered to be indicative of poor outcome. The authors examined whether there was a subset of men with SV invasion who had long-term prostate-specific antigen (PSA) progression-free survival. METHODS:Data were examined fr...

journal_title：Cancer

authors： Freedland SJ,Aronson WJ,Presti JC Jr,Amling CL,Terris MK,Trock B,Kane CJ

更新日期：2004-04-15 00:00:00

abstract：:In a 3 1/2 year cytogenetic study of 107 leukemia patients diagnosed in childhood and adloescence, 8 presented with chronic myelogenous leukemia (CML). Seven of the 8 had chromosomal abnormalities. Six had the Ph1 chromosome; 5 had the usual 9;22 translocation. Two patients had involvement with chromosome 15; one had ...

journal_title：Cancer

authors： Hays T,Morse H,Peakman D,Rose B,Robinson A

更新日期：1979-07-01 00:00:00

abstract：:As part of epidemiologic studies of human T-lymphotropic virus (HTLV)-I-associated malignancies in Jamaica, the authors evaluated 26 patients with non-Hodgkin's lymphoma for the presence of integrated HTLV-I provirus in their malignant cells. Fifteen of 26 patients had integrated provirus. All 15 also were HTLV-I anti...

journal_title：Cancer

authors： Clark JW,Gurgo C,Franchini G,Gibbs WN,Lofters W,Neuland C,Mann D,Saxinger C,Gallo RC,Blattner WA

更新日期：1988-04-01 00:00:00

abstract：:Flow cytometric analysis of nuclear DNA content was performed on excised malignant tissue of the esophagus. The DNA ploidy pattern was compared with a variety of histologic parameters and the subsequent clinical course to determine whether or not this pattern is associated with the mode of malignant potentiality. Of t...

journal_title：Cancer

authors： Kaketani K,Saito T,Kobayashi M

更新日期：1989-08-15 00:00:00

abstract：:Eleven patients with advanced soft tissue sarcoma were treated with whole body hyperthermia (41.8 degrees C-43.0 degrees C) for 2 hours, doxorubicin (45 mg/m2) at the beginning of peak temperature and cyclophosphamide (1000 mg/m2) 6 hours after doxorubicin. Warming was accomplished with a nylon and vinyl mesh water pe...

journal_title：Cancer

authors： Gerad H,van Echo DA,Whitacre M,Ashman M,Helrich M,Foy J,Ostrow S,Wiernik PH,Aisner J

更新日期：1984-06-15 00:00:00

abstract：BACKGROUND:Immune checkpoint inhibitors (ICIs) represent an appealing treatment for patients with advanced urothelial cancer (aUC) and a poor performance status (PS). However, the benefit of ICIs for patients with a poor PS remains unknown. It was hypothesized that a poor Eastern Cooperative Oncology Group (ECOG) PS (≥...

journal_title：Cancer

authors： Khaki AR,Li A,Diamantopoulos LN,Bilen MA,Santos V,Esther J,Morales-Barrera R,Devitt M,Nelson A,Hoimes CJ,Shreck E,Assi H,Gartrell BA,Sankin A,Rodriguez-Vida A,Lythgoe M,Pinato DJ,Drakaki A,Joshi M,Isaacsson Velho P

更新日期：2020-03-15 00:00:00

abstract：:Renal cell carcinoma (RCC) evokes an immune response, which occasionally has resulted in spontaneous and dramatic remissions. In an attempt to reproduce or accentuate this response, various immunotherapeutic strategies have been studied. The most consistent antitumor activity has been reported with interferon-alpha (I...

journal_title：Cancer

authors： McDermott DF

更新日期：2009-05-15 00:00:00

abstract：BACKGROUND:Primary and metastatic malignancies that originate in the sinonasal tract are rare and histologically diverse. The role of fine-needle aspiration biopsy (FNAB) and the cytomorphologic features of these tumors have not been specifically addressed. METHODS:The authors reviewed 22 cytology cases (20 FNABs, 1 s...

journal_title：Cancer

authors： Helsel JC,Bardales RH,Mukunyadzi P

更新日期：2003-04-25 00:00:00

abstract：:The pathologic features, clinical presentation and natural history of hepatocellular carcinoma (HCC) developing in the noncirrhotic liver were studied in 61 patients against a background of 63 patients seen concurrently with HCC complicating cirrhosis. Noncirrhotic HCC had a bimodal age distribution, with females pred...

journal_title：Cancer

authors： Smalley SR,Moertel CG,Hilton JF,Weiland LH,Weiand HS,Adson MA,Melton LJ 3rd,Batts K

更新日期：1988-10-01 00:00:00

abstract：BACKGROUND:Most commercial fecal occult blood tests (FOBT) used for colorectal carcinoma screening of Western populations are guaiac-based, manually developed, subjective, and sensitive to dietary components. Preliminary studies demonstrated the unsuitability of these tests for screening a Chinese population. The goal ...

journal_title：Cancer

authors： Wong WM,Lam SK,Cheung KL,Tong TS,Rozen P,Young GP,Chu KW,Ho J,Law WL,Tung HM,Choi HK,Lee YM,Lai KC,Hu WH,Chan CK,Yuen MF,Wong BC

更新日期：2003-05-15 00:00:00

abstract：BACKGROUND:Studies postulate that certain religious beliefs related to medical care influence the end-of-life (EOL) medical decision making and care of patients with advanced cancer. Because to the best of the authors' knowledge no current measure explicitly assesses such beliefs, in the current study the authors intro...

journal_title：Cancer

authors： Balboni TA,Prigerson HG,Balboni MJ,Enzinger AC,VanderWeele TJ,Maciejewski PK

更新日期：2019-05-01 00:00:00

abstract：:Results of remission induction therapy in refractory acute nonlymphocytic leukemia (ANLL) has been improved since the introduction of high-dose cytosine arabinoside. However, the toxicity of these regimens attributes to an early death rate of about 20% to 30%. The authors treated 37 poor-risk patients with ANLL with i...

journal_title：Cancer

authors： Dekker AW,Nieuwenhuis HK,Verdonck LF

更新日期：1990-05-01 00:00:00

abstract：BACKGROUND:The current study was conducted to evaluate the Patient-Reported Outcomes Measurement Information System Depression Short Form (PROMIS-D-SF) as a screening measure for young adult cancer survivors (YACS) compared with a structured diagnostic interview. METHODS:A total of 249 YACS (aged 18-40 years) complete...

journal_title：Cancer

authors： Recklitis CJ,Blackmon JE,Chang G

更新日期：2020-04-01 00:00:00

abstract：BACKGROUND:Malignant fibrous histiocytoma (MFH) is a neoplasm of late adult life and often is reported in the pediatric population. It is thought to behave more benignly in children than in adults. METHOD:Clinical and pathologic features, treatment, and outcome of nine pediatric patients seen at British Columbia's Chi...

journal_title：Cancer

authors： Cole CH,Magee JF,Gianoulis M,Rogers PC

更新日期：1993-06-15 00:00:00

abstract：:Of 55 patients with Ollier's disease seen at the Mayo Clinic between 1907 and 1985, 16 had malignant bone neoplasms: 12 chondrosarcomas, two dedifferentiated chondrosarcomas, one chordoma, and one osteosarcoma. One patient had a chondrosarcoma in two different bones. These findings suggest that approximately 30% of pa...

journal_title：Cancer

authors： Liu J,Hudkins PG,Swee RG,Unni KK

更新日期：1987-04-01 00:00:00

abstract：:Research trends on quality of life outcomes for cancer survivors are discussed. Epidemiologic data indicate that female cancer survivors, coming primarily from patient groups with gynecologic, breast, and colorectal cancers, will outnumber male survivors 3 to 1. Male survivors will come from the ranks of patient group...

journal_title：Cancer

authors： Andersen BL

更新日期：1994-08-15 00:00:00

abstract：:Transgenic model systems provide tools for obtaining information that clarifies important relationships between genetic alterations and carcinogenesis. One such relationship is the induction of specific growth factor activities by dominantly acting oncogenes. Using a "transgenic organ" model referred to as mouse prost...

journal_title：Cancer

authors： Thompson TC,Truong LD,Timme TL,Kadmon D,McCune BK,Flanders KC,Scardino PT,Park SH

更新日期：1993-02-01 00:00:00

abstract：:A 54-year-old man with hepatocellular carcinoma (HCC) of the typical trabecular pattern exhibiting unusual histologic features, both osteoid and bone formations, is reported. The tumor was associated with well-developed cirrhosis; thus, this may be different from mixed hepatic tumors of adults with bone formations bec...

journal_title：Cancer

authors： Maeda M,Kanayama M,Uchida T,Hasumura Y,Takeuchi J

更新日期：1986-01-01 00:00:00

abstract：:Associations were sought between specific histocompatibility antigens (HLA) of the human major histocompatibility complex and the incidence of head and neck squamous cell carcinoma (SqCC). Seventy sequential patients with SqCC and 217 control subjects from the same geographic region were typed for HLA-A, HLA-B, and HL...

journal_title：Cancer

authors： Houck JR,Romano PJ,Bartholomew M,Smith PJ,Kloszewski F,Vesell ES

更新日期：1992-05-01 00:00:00