Expression of vascular endothelial growth factor in early cutaneous melanocytic lesion progression.

abstract：BACKGROUND:Colorectal cancer (CRC) develops through the alteration of several critical pathways. This study was aimed at evaluating the influence of critical pathways on survival outcomes for patients with CRC. METHODS:Targeted next-generation sequencing of 40 genes included in the 5 critical pathways of CRC (WNT, P53...

journal_title：Cancer

authors： Lee DW,Han SW,Cha Y,Bae JM,Kim HP,Lyu J,Han H,Kim H,Jang H,Bang D,Huh I,Park T,Won JK,Jeong SY,Park KJ,Kang GH,Kim TY

更新日期：2017-09-15 00:00:00

abstract：:Fibronectin, a high molecular weight glycoprotein component of the extracellular matrix, was localized extracellularly and intracellularly in the nuclei and the cytoplasm of hepatocellular carcinomas (HCC) by the use of the biotin-avidin method on paraffin-embedded, pepsin-treated tissue. The specificity of the staini...

journal_title：Cancer

authors： Jagirdar J,Ishak KG,Colombo M,Brambilla C,Paronetto F

更新日期：1985-10-01 00:00:00

abstract：BACKGROUND:Recently, a highly sensitive fluorescent imaging technique was developed for the real-time identification of hepatic tumors. The authors applied this procedure for the intraoperative detection of radiographically occult hepatic micrometastases from pancreatic cancer. METHODS:Forty-nine consecutive patients ...

journal_title：Cancer

authors： Yokoyama N,Otani T,Hashidate H,Maeda C,Katada T,Sudo N,Manabe S,Ikeno Y,Toyoda A,Katayanagi N

更新日期：2012-06-01 00:00:00

abstract：:Two cases of primary linitis plastica of the large intestine will be presented and discussed. Characteristic clinical features of this type of adenocarcinoma of the large intestine include younger age of presentation, low incidence of hepatic metastasis and a high incidence of ovarian, lymph node and peritoneal metast...

journal_title：Cancer

authors： Amorn Y,Knight WA Jr

更新日期：1978-06-01 00:00:00

abstract：BACKGROUND:Endometrial carcinoma is one of the most frequent malignancies in the female genital tract, and its incidence has been increasing in Japan. Histologic grade is an important factor for organizing treatment strategies, including hormone therapy, and for predicting the prognosis of the patient. The objective of...

journal_title：Cancer

authors： Nishimura Y,Watanabe J,Jobo T,Hattori M,Arai T,Kuramoto H

更新日期：2005-02-25 00:00:00

abstract：BACKGROUND:To enhance the efficacy of chemotherapy for medullary thyroid carcinoma (MTC), we evaluated the effect of combining radioimmunotherapy (RAIT) with 90Y-anticarcinoembryonic antigen (CEA) monoclonal antibody MN-14 and chemotherapy in nude mice bearing human MTC xenografts. A preliminary study evaluated doxorub...

journal_title：Cancer

authors： Stein R,Chen S,Reed L,Richel H,Goldenberg DM

更新日期：2002-01-01 00:00:00

abstract：:Previous studies and those of the authors have reported about raised levels of lipid-bound sialic acid (LSA) in sera of patients with various neoplasms. Most authors have used the method of Katopodis and Stock for isolating serum LSA. Because of the discrepancy of the amount of extracted LSA with the content of pure g...

journal_title：Cancer

authors： Voigtmann R,Pokorny J,Meinshausen A

更新日期：1989-12-01 00:00:00

abstract：BACKGROUND:Despite published reports regarding the association of elevated circulating CD44 and CD54 levels with unfavorable outcome in non-Hodgkin lymphoma (NHL) and chronic lymphocytic leukemia (CLL), little is known about therapy-related changes in either adhesion molecule. In an attempt to evaluate the effect of in...

journal_title：Cancer

authors： Beksaç M,Arat M,Akan H,Koç H,Ilhan O,Ozcan M

更新日期：2000-10-01 00:00:00

abstract：:Three children with nonlymphoblastic, non-Hodgkin's lymphomas, showed morphologic features that suggested nonlymphoblastic T-cell origin. Tissue for immunologic study was available from two of the three patients; both showed immunophenotypes of T-cells. Although nearly all T-cell lymphomas in children are lymphoblasti...

journal_title：Cancer

authors： Bitter MA,Nachman J,Jones N,Franklin WA,Le Beau MM,Vardiman JW

更新日期：1987-06-15 00:00:00

abstract：:Serum ferritin levels were monitored in nine patients with acute lymphoblastic leukemia (ALL), nine patients with acute nonlymphoblastic leukemia (ANLL), four patients with chronic myelogenous leukemia (CML), three patients with non-Hodgkin's lymphoma (NHL), and three patients with severe aplastic anemia (SAA) undergo...

journal_title：Cancer

authors： Or R,Matzner Y,Konijn AM

更新日期：1987-09-01 00:00:00

abstract：:Twenty-four patients with metastatic cancer of the choroid were seen in the Department of Therapeutic Radiology, Rush-Presbyterian--St. Luke's Medical Center, Chicago, between 1964 and 1975. One fourth of the patients had involvement in both eyes, for a total of 30 eyes involved with metastatic cancer. The most common...

journal_title：Cancer

authors： Reddy S,Saxena VS,Hendrickson F,Deutsch W

更新日期：1981-02-15 00:00:00

abstract：BACKGROUND:Transitional cell carcinoma (TCC) is rare in the female genital tract. Although it is most common in the ovary, small series of cases in the cervix have been reported, with isolated cases described in the fallopian tube, adnexa uteri, and endometrium. METHODS:Eight cases of primary TCC involving the endomet...

journal_title：Cancer

authors： Lininger RA,Ashfaq R,Albores-Saavedra J,Tavassoli FA

更新日期：1997-05-15 00:00:00

abstract：:One hundred fifty-six evaluable patients with metastatic breast cancer were treated with vincristine, Adriamycin and cyclophosphamide alternating at fixed intervals with 5-FU and methotrexate. Immunotherapy with BCG or MER-BCG was administered to all patients in two consecutive treatment programs. Overall objective re...

journal_title：Cancer

authors： Blumenschein GR,Hortobagyi GN,Richman SP,Gutterman JU,Tashima CK,Buzdar AU,Burgess MA,Livingston RB,Hersh EM

更新日期：1980-02-15 00:00:00

abstract：BACKGROUND:The question of whether manual dissection when searching for metastatic lymph nodes from rectal cancer (less than 5 mm) is a reliable method remains controversial. METHODS:We examined 50 consecutive cases of primary adenocarcinoma of the rectum treated with a sphincter-sparing total rectum resection, total ...

journal_title：Cancer

authors： Andreola S,Leo E,Belli F,Bufalino R,Tomasic G,Lavarino C,Baldini MT,Meroni E

更新日期：1996-02-15 00:00:00

abstract：BACKGROUND:The delivery of effective treatment for pediatric solid tumors poses a particular challenge to centers in middle-income countries (MICs) that already are vigorously addressing pediatric cancer. The objective of this study was to improve the current understanding of barriers to effective treatment of pediatri...

journal_title：Cancer

authors： Friedrich P,Ortiz R,Fuentes S,Gamboa Y,Ah Chu-Sanchez MS,Arambú IC,Montero M,Báez F,Rodríguez-Galindo C,Antillón-Klussmann F,Central American Association of Pediatric Hematologists and Oncologists (AHOPCA).

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Interactions between bone marrow-derived cytokines, growth factors, and tumors play a critical role in both the homing of tumors to the bone and the development of bone metastasis. Bone is a storehouse of latent growth factors produced by stromal cells and osteoblasts that, when activated during osteoclastic...

journal_title：Cancer

authors： David Roodman G

更新日期：2003-02-01 00:00:00

abstract：:From November 1973 to May 1986, 50 patients with Stage I epithelial ovarian cancer were treated at the University of Kentucky Medical Center (Lexington, KY) with oral Alkeran (melphalan) chemotherapy after primary surgery. Twenty-two patients had Grade 1 tumors, 23 patients had Grade 2 tumors, and five patients had Gr...

journal_title：Cancer

authors： Gallion HH,van Nagell JR,Donaldson ES,Higgins RV,Powell DE,Kryscio RJ

更新日期：1989-03-15 00:00:00

abstract：:Diagnostic advances currently have exceeded therapeutic gain. The present, however, is a transition phase. Chemotherapy, for example, has become curative for some tumors in recent years, rather than merely palliative, due to the precision permitted by advances in molecular biology. At this time, acceleration in the ba...

journal_title：Cancer

authors： Gusberg SB

更新日期：1987-10-15 00:00:00

abstract：BACKGROUND:The majority of colorectal carcinomas, if not all, arise from a benign adenoma. The DNA of the carcinomatous cells frequently has mutations in several genes. However, it is not exactly clear when during the neoplastic process each mutation develops. An adenoma with an area of in situ carcinoma provides an op...

journal_title：Cancer

authors： Zauber NP,Sabbath-Solitare M,Marotta SP,Bishop DT

更新日期：1999-07-01 00:00:00

abstract：BACKGROUND:Lysosomal proteases are implicated in cancer progression and metastasis. In the current study, using subtraction cloning for genes that are differentially expressed in metastasis, the authors isolated a clone encoding ceroid lipofuscinosis, neuronal 2 (CLN2), which is a lysosomal serine protease defective in...

journal_title：Cancer

authors： Tsukamoto T,Iida J,Dobashi Y,Furukawa T,Konishi F

更新日期：2006-04-01 00:00:00

abstract：:The radionuclide, gallium-67, accumulates in a wide variety of neoplastic and inflammatory lesions. Diffuse bilateral lung localization of 67Ga occurred in two cases of interstitial pneumonitis associated with bleomycin therapy. Clinical symptoms and laboratory evaluation of pulmonary status correlated with scintigrap...

journal_title：Cancer

authors： Richman SD,Levenson SM,Bunn PA,Flinn GS,Johnston GS,DeVita VT

更新日期：1975-12-01 00:00:00

abstract：:The greatest decrease in breast cancer mortality is likely to derive from applying globally existing therapies at an earlier stage. A high priority of the World Health Organization (WHO) cancer control program is the outreach approach that promotes worldwide access to cancer therapies of proven values. Therefore, the ...

journal_title：Cancer

authors： Koroltchouk V,Stanley K,Stjernswärd J

更新日期：1990-06-15 00:00:00

abstract：:Although weight loss has an adverse impact on cancer patient survival, the ability of caloric provision via total parenteral nutrition (TPN) to favorably influence outcome in chemotherapy-treated populations is not established. In randomized trials, no significant improvement in either response or survival was associa...

journal_title：Cancer

authors： Chlebowski RT

更新日期：1985-01-01 00:00:00

abstract：:The clinical and pathologic features of 33 pseudomalignant lesions of the gastrointestinal tract with bizarre stromal cells are reported. Deceptive histologic changes were identified in ulcers of seven patients and in inflammatory polyps of 26. A misdiagnosis of malignant neoplasm was made in six of the 33 patients (t...

journal_title：Cancer

authors： Shekitka KM,Helwig EB

更新日期：1991-04-15 00:00:00

abstract：:Extensive bone marrow necrosis is an unusual histologic finding most commonly identified after autopsy. We describe a patient with poorly differentiated lymphocytic lymphoma who manifested pancytopenia and marrow necrosis. Bone marrow scanning with 99mTc-sulfur-minicolloid provided a noninvasive means to assess the ex...

journal_title：Cancer

authors： Cowan JD,Rubin RN,Kies MS,Cerezo L

更新日期：1980-11-15 00:00:00

abstract：:The monitoring utility of serial patterns of a single marker (carcinoembryonic antigen) level and multiple marker (three carbohydrates-fucose, mannose and galactose) levels in patients with small cell carcinoma of the lung was investigated using a quantitative approach. A serial multiple regression (SMR) model was for...

journal_title：Cancer

authors： Woo KB,Waalkes P,Abeloff MD,Ettinger DS,McNitt KL,Gehrke CW

更新日期：1981-10-01 00:00:00

abstract：BACKGROUND:Race is associated with patterns of presentation and survival outcomes of gastric cancer in the United States. However, the impact of race on the receipt of guideline-recommended care is not well characterized. By using current recommendations, the authors examined the association between race and guideline-...

journal_title：Cancer

authors： Al-Refaie WB,Gay G,Virnig BA,Tseng JF,Stewart A,Vickers SM,Tuttle TM,Feig BW

更新日期：2010-01-15 00:00:00

abstract：:A clinical trial was conducted at the Institut Gustave Roussy between October 1972 and December 1980 to compare mastectomy with local excision plus Cobalt-irradiation, in patients with breast cancer tumors of 20 mm in diameter or less at macroscopic examination. Low-axillary dissection and extemporaneous histologic ex...

journal_title：Cancer

authors： Sarrazin D,Lê M,Rouëssé J,Contesso G,Petit JY,Lacour J,Viguier J,Hill C

更新日期：1984-03-01 00:00:00

abstract：BACKGROUND:Single-walled carbon nanotubes (SWNTs) have remarkable physicochemical properties that may have several medical applications. The authors have discovered a novel property of SWNTs-heat release in a radiofrequency (RF) field-that they hypothesized may be used to produce thermal cytotoxicity in malignant cells...

journal_title：Cancer

authors： Gannon CJ,Cherukuri P,Yakobson BI,Cognet L,Kanzius JS,Kittrell C,Weisman RB,Pasquali M,Schmidt HK,Smalley RE,Curley SA

更新日期：2007-12-15 00:00:00

abstract：:From February 1972 to July 1975, 200 lung cancer patients were seen at the University of Rochester Cancer Center's Division of Radiation Oncology; 40% had squamous cell tumors and 87.5% had advanced disease localized to the thorax. Of the 160 patients who completed treatment, 101 were treated with continuous therapy s...

journal_title：Cancer

authors： Salazar OM,Rubin P,Brown JC,Feldstein ML,Keller BE

更新日期：1976-06-01 00:00:00