Cost effectiveness of proton therapy compared with photon therapy in the management of pediatric medulloblastoma.

abstract：:In 1963 an electron beam became available, making irradiation of the chest wall technically easy. In addition to peripheral lymphatic irradiation in patients with positive axillary nodes and/or the tumor in the inner quadrants or centrally located, patients with tumor larger than 5 cm or with grave signs and/or a sign...

journal_title：Cancer

authors： Tapley ND,Spanos WJ Jr,Fletcher GH,Montague ED,Schell S,Oswald MJ

更新日期：1982-03-15 00:00:00

abstract：:A case of fatal acute hepatic vein thrombosis occurred during treatment for Hodgkin's disease. At necropsy no evidence of Hodgkin's disease or obliterative venoocclusive disease of the liver was found. We speculate that Adriamycin, DTIC and/or vinblastine may have been responsible for this unusual disorder. ...

journal_title：Cancer

authors： Houghton AN,Shafi N,Rickles FR

更新日期：1979-12-01 00:00:00

abstract：:Between September 1976 and May 1980, 135 patients with operable breast cancer and positive axillary nodes received l-phenylalanine mustard, adjunct to surgery, 0.15 mg/kg for five days, six weekly, and were randomised prospectively to levamisole 150 mg for three days, two weekly, or a placebo. Treatment was continued ...

journal_title：Cancer

authors： Kay RG,Mason BH,Stephens EJ,Arthur JF,Hitchcock GC,Trindall PL,Rodgers R,Mullins P

更新日期：1983-06-01 00:00:00

abstract：:The antitumor effect of human leukocyte interferon was investigated on ten patients with malignant brain tumor. In eight cases of primary tumor, IFN alone was administered when their recurrent sign was evident. A dose of 3 X 10(6) IU or 1 X 10(6) IU of IFN was injected intramuscularly two or three times a week in high...

journal_title：Cancer

authors： Hirakawa K,Ueda S,Nakagawa Y,Suzuki K,Fukuma S,Kita M,Imanishi J,Kishida T

更新日期：1983-06-01 00:00:00

abstract：:Almost all patients with prostatic cancer will eventually escape the control of the first-line endocrine therapy and relapse. This escape is attributed to selecting and/or cloning preexisting or de novo appearing hormone-independent or resistant cell lines and occurs in most patients after a median time of 12 to 18 mo...

journal_title：Cancer

authors： Mahler C,Denis L

更新日期：1992-07-01 00:00:00

abstract：:109 cases of breast cancer were treated by tumorectomy and radiotherapy or radiotherapy alone. Almost 30% with small tumors (T1, T2) were considered inoperable for medical reasons and 70% refused mastectomy. Over the past five years the number of patients refusing mastectomy has definitely increased. 59 cases of surgi...

journal_title：Cancer

authors： Alpert S,Ghossein NA,Stacey P,Migliorelli FA,Efron G,Krishnaswamy V

更新日期：1978-10-01 00:00:00

abstract：:In a 3 1/2 year cytogenetic study of 107 leukemia patients diagnosed in childhood and adloescence, 8 presented with chronic myelogenous leukemia (CML). Seven of the 8 had chromosomal abnormalities. Six had the Ph1 chromosome; 5 had the usual 9;22 translocation. Two patients had involvement with chromosome 15; one had ...

journal_title：Cancer

authors： Hays T,Morse H,Peakman D,Rose B,Robinson A

更新日期：1979-07-01 00:00:00

abstract：BACKGROUND:Clips are often placed to mark axillary nodes with biopsy-confirmed metastases in patients with breast cancer. The evaluation of clipped nodes after chemotherapy can identify patients who have eradication of nodal disease. The goal of this study was to determine whether preoperative fine-needle aspiration (F...

journal_title：Cancer

authors： Caudle AS,Kuerer HM,Krishnamurthy S,Shin K,Hobbs BP,Ma J,Mittendorf EA,Washington AC,DeSnyder SM,Black DM,Hunt KK,Yang WT

更新日期：2019-02-01 00:00:00

abstract：:Since June 1978, 57 patients with primary osteogenic sarcoma of an extremity were treated with high-dose methotrexate (HDMTX) and citrovorum factor rescue (CFR), Adriamycin, and the combination of bleomycin, cyclophosphamide and dactinomycin (BCD) given for 4-16 weeks prior to definitive surgery. Histologic examinatio...

journal_title：Cancer

authors： Rosen G,Caparros B,Huvos AG,Kosloff C,Nirenberg A,Cacavio A,Marcove RC,Lane JM,Mehta B,Urban C

更新日期：1982-03-15 00:00:00

abstract：:A single dose of N-nitrosobis(2-oxopropyl)amine, a carcinogen for hamster pancreas, was administered to hamsters with regenerating pancreas 60 hours after initiation of regeneration when the maximum number of acinar cells are in S phase of the cell cycle. This led to nucleolar segregation and mitotic abnormalities fro...

journal_title：Cancer

authors： Scarpelli DG,Rao MS

更新日期：1981-03-15 00:00:00

abstract：BACKGROUND:9-Aminocamptothecin (9AC) and its parent compound, camptothecin, have shown outstanding preclinical activity against colorectal carcinoma. Irinotecan (CPT-11), another camptothecin derivative, has demonstrated clinical activity in patients with 5-fluorouracil (5-FU)-refractory colorectal carcinoma. METHODS:...

journal_title：Cancer

authors： Saltz LB,Kemeny NE,Tong W,Harrison J,Berkery R,Kelsen DP

更新日期：1997-11-01 00:00:00

abstract：:Breast cancer is serious public health problem in countries of all resource levels. Although major advances in the detection and treatment of the disease have occurred in higher income settings, similar progress has been slow or scarce in most low- and middle-income countries (LMCs). The poorer outcomes in LMCs may re...

journal_title：Cancer

authors： Harford J,Azavedo E,Fischietto M,Breast Health Global Initiative Healthcare Systems Panel.

更新日期：2008-10-15 00:00:00

abstract：:Levamisole, used in vitro at therapeutic concentrations, was found able to restore the defective Fc-receptor activity of cancer patient neutrophils. In addition, the drug prevented the inhibition of normal neutrophils Fc-receptor function by cancer patient sera. The neutrophil Fc-receptor function was also restored in...

journal_title：Cancer

authors： Patrone F,Dallegri F,Pistoia V,Ghio R,Sacchetti C

更新日期：1985-04-15 00:00:00

abstract：BACKGROUND:Despite significant advances in understanding the biology of renal cell carcinoma (RCC) during the past decade, metastatic disease remains nearly incurable and a major medical challenge. Because RCC is known to be immunogenic, immunotherapeutic agents such as recombinant human interleukin-2 (rIL-2) and inter...

journal_title：Cancer

authors： Bukowski RM

更新日期：1997-10-01 00:00:00

abstract：:Sixty percent of all cancer occurs in persons aged > or =65 years. This article provides an overview of aspects of the burden of cancer in the elderly, highlighting certain demographic and epidemiologic data. It served as a frame of reference for participants in the Oncology Geriatric Education Retreat, San Juan, Puer...

journal_title：Cancer

authors： Yancik R

更新日期：1997-10-01 00:00:00

abstract：BACKGROUND:A rare occurrence, about 1500 men in the United States develop breast carcinoma each year. Little is known about survival patterns at the population level, particularly about racial/ethnic variation. METHODS:Using data from the Surveillance, Epidemiology, and End Results Program, we examined survival rates ...

journal_title：Cancer

authors： O'Malley CD,Prehn AW,Shema SJ,Glaser SL

更新日期：2002-06-01 00:00:00

abstract：BACKGROUND:Angiotropic large cell lymphoma (ALCL) is characterized by the intravascular proliferation of malignant lymphoid cells in small and medium-sized blood vessels. In the current study, the authors report an unusual case in which the initial presentation of the ALCL was that of superior vena cava (SVC) syndrome....

journal_title：Cancer

authors： Savarese DM,Zavarin M,Smyczynski MS,Rohrer MJ,Hutzler MJ

更新日期：2000-12-15 00:00:00

abstract：BACKGROUND:African-American (AA) and white patients with early-stage disease who were treated with breast conservation therapy (BCT) were examined to detect differences in clinicopathologic features and outcomes as a function of race. METHODS:Clinical data from the charts of 2164 white and 207 AA patients treated with...

journal_title：Cancer

authors： Moran MS,Yang Q,Harris LN,Jones B,Tuck DP,Haffty BG

更新日期：2008-11-01 00:00:00

abstract：BACKGROUND:Reliable predictive biomarkers are required to address the challenge of disease recurrence after thyroid cancer surgery. For this study, the authors assessed the association of cellular-based and serum-based immunologic mediators with thyroid cancer recurrence. METHODS:Leukocyte subset counts and immune reg...

journal_title：Cancer

authors： Owonikoko TK,Hossain MS,Bhimani C,Chen Z,Kim S,Ramalingam SS,Sun SY,Shin DM,Waller EK,Khuri FR

更新日期：2013-04-15 00:00:00

abstract：:Numerous morphologic features have been described in bone marrow and peripheral blood in myelodysplastic syndrome (MDS). We draw attention to a high incidence of a subtle morphologic feature, internuclear bridging (INB), not previously recognized as a morphologic feature in MDS. The occurrence of INB in MDS suggests a...

journal_title：Cancer

authors： Head DR,Kopecky K,Bennett JM,Grenier K,Morrison FS,Miller KB,Grever MR

更新日期：1989-12-01 00:00:00

abstract：BACKGROUND:The reliability of fine-needle aspiration cytology (FNAC) of breast masses in males could be compromised by lack of experience because breast carcinoma is rare in males and FNAC is not often used. In addition, FNAC of the more often encountered gynecomastia may lead to overdiagnosis. Therefore, in the curren...

journal_title：Cancer

authors： Westenend PJ,Jobse C

更新日期：2002-04-25 00:00:00

abstract：:Disease that is known to have extended beyond the prostatic capsule is unlikely to be cured by radical surgical excision, although the primary tumor may be controlled by external irradiation. The development of progressive (metastatic) disease is common and may be retarded by hormonal therapy. The timing of such treat...

journal_title：Cancer

authors： Smith PH

更新日期：1993-02-01 00:00:00

abstract：BACKGROUND:Previous studies have indicated that the incidence and mortality rates for multiple myeloma have increased in the United States. The authors reported on the incidence of multiple myeloma in Olmsted County, Minnesota, between 1991 and 2001 and on trends in multiple myeloma incidence over the last 56 years. M...

journal_title：Cancer

authors： Kyle RA,Therneau TM,Rajkumar SV,Larson DR,Plevak MF,Melton LJ 3rd

更新日期：2004-12-01 00:00:00

abstract：BACKGROUND:Bortezomib has preclinical and clinical in B-cell lymphomas, both alone and in combination with other agents. A phase 1 evaluation was conducted of bortezomib with rituximab plus cyclophosphamide, doxorubicin, vincristine, and prednisone (R-CHOP) in patients with untreated diffuse large B-cell lymphoma (DLBC...

journal_title：Cancer

authors： Furman RR,Martin P,Ruan J,Cheung YK,Vose JM,LaCasce AS,Elstrom R,Coleman M,Leonard JP

更新日期：2010-12-01 00:00:00

abstract：BACKGROUND:Antibacterial prophylaxis with quinolone antibiotics has resulted in an increase in streptococcal infections among bone marrow transplantation (BMT) recipients with myelosuppression. Oral ulceration (mucositis), which frequently occurs as a consequence of chemotherapy, has been implicated as a significant po...

journal_title：Cancer

authors： Ruescher TJ,Sodeifi A,Scrivani SJ,Kaban LB,Sonis ST

更新日期：1998-06-01 00:00:00

abstract：:The relationship between cytogenetic findings and prognosis in 51 pediatric patients with neuroblastoma is described. Patients were classified into the following four groups based on karyotypic findings: (1) near diploidy, 42 to 47 chromosomes (n = 11); (2) hyperdiploidy, 50 to 56 chromosomes (n = 4); (3) near triploi...

journal_title：Cancer

authors： Hayashi Y,Kanda N,Inaba T,Hanada R,Nagahara N,Muchi H,Yamamoto K

更新日期：1989-01-01 00:00:00

abstract：:A 78-year-old Japanese man with chronic liver disease developed hypervascular liver tumors accompanied by marked elevation of alphafetoprotein value (the highest level; 26200 ng/ml) and pathologic fracture of the femur. After an operation for the fracture followed by gastrointestinal bleeding and repeated transfusions...

journal_title：Cancer

authors： Sato Y,Fujiwara K,Nakagawa S,Kanishima S,Ohta Y,Oka Y,Hayashi S,Oka H

更新日期：1985-08-01 00:00:00

abstract：:Oral submucous fibrosis (OSF) is a chronic disease of the oral mucosa characterized by inflammation and a progressive fibrosis of the lamina propria and deeper connective tissues. It is a condition predominantly seen among people of Indian origin, and an epidemiologic survey done a decade ago showed no less than 250,0...

journal_title：Cancer

authors： Pillai R,Balaram P,Reddiar KS

更新日期：1992-04-15 00:00:00

abstract：BACKGROUND:Prognostic implications of overexpression of the HER-2 gene in nonsmall cell lung carcinoma (NSCLC) are a matter of controversy. Many conflicting results have been reported from different laboratories. METHODS:A metaanalysis of published studies was performed for this quantitative review of the effects of H...

journal_title：Cancer

authors： Nakamura H,Kawasaki N,Taguchi M,Kabasawa K

更新日期：2005-05-01 00:00:00

abstract：:Primary malignant lymphomas of the breast (PBL) are uncommon. The authors report the clinical, histologic, and immunoperoxidase findings on 20 cases recorded at the Alberta Cancer Registry over the last 23 years. These cases were then added to material on 257 cases abstracted from the literature and analyzed. It was f...

journal_title：Cancer

authors： Hugh JC,Jackson FI,Hanson J,Poppema S

更新日期：1990-12-15 00:00:00