Epidemiology of cancer of the vulva. A case-control study.

Abstract:

:Few epidemiologic studies have been undertaken to investigate the etiology of cancer of the vulva. To identify risk factors associated with this cancer, a case-control study was conducted in 149 patients with histologically proven vulvar carcinoma and the same number of control patients matched for age, race, marital status, and hospital from five U.S. metropolitan areas. As previously suspected, we found prior histories of leukoplakia of the vulva, inflammation of the vulva or vagina, and urogenital cancer to be significantly associated with vulvar cancer. In addition, we found moderately high odds ratios associated with occupational histories of private household maids and servants, and work in laundry, cleaning, and other garment services. A slightly increased odds ratio was associated with coffee consumption and a dose-response effect was demonstrated. The findings suggest that environmental exposures may play a role in vulvar carcinogenesis.

journal_name

Cancer

journal_title

Cancer

authors

Mabuchi K,Bross DS,Kessler II

doi

10.1002/1097-0142(19850415)55:8<1843::aid-cncr2820

subject

Has Abstract

pub_date

1985-04-15 00:00:00

pages

1843-8

issue

8

eissn

0008-543X

issn

1097-0142

journal_volume

55

pub_type

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