Abstract:
:Few epidemiologic studies have been undertaken to investigate the etiology of cancer of the vulva. To identify risk factors associated with this cancer, a case-control study was conducted in 149 patients with histologically proven vulvar carcinoma and the same number of control patients matched for age, race, marital status, and hospital from five U.S. metropolitan areas. As previously suspected, we found prior histories of leukoplakia of the vulva, inflammation of the vulva or vagina, and urogenital cancer to be significantly associated with vulvar cancer. In addition, we found moderately high odds ratios associated with occupational histories of private household maids and servants, and work in laundry, cleaning, and other garment services. A slightly increased odds ratio was associated with coffee consumption and a dose-response effect was demonstrated. The findings suggest that environmental exposures may play a role in vulvar carcinogenesis.
journal_name
Cancerjournal_title
Cancerauthors
Mabuchi K,Bross DS,Kessler IIdoi
10.1002/1097-0142(19850415)55:8<1843::aid-cncr2820subject
Has Abstractpub_date
1985-04-15 00:00:00pages
1843-8issue
8eissn
0008-543Xissn
1097-0142journal_volume
55pub_type
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